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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Medula Berkala Kedokteran Prosiding Seminar Nasional Pakar Manuju : Malahayati Nursing Journal Jurnal Ilmu Kedokteran dan Kesehatan Acta Biochimica Indonesiana Jurnal Ilmiah Kesehatan Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Ilmu Kesehatan Indonesia (JIKSI) MAHESA : Malahayati Health Student Journal Prosiding Konferensi Nasional PKM-CSR
Evi Kurniawaty
Universitas Lampung
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Acta Biochimica Indonesiana

 1 
The effect of mangrove (Rhizophora apiculata) bark extract ethanol on histopathology pancreas of male white rats Sprague Dawley strain exposed to cigarette smoke Syazili Mustofa; W Bahagia; Evi Kurniawaty; S Rahmanisa; Kholis Abdurachim Audah
Acta Biochimica Indonesiana Vol. 1 No. 1 (2018): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.v1i1.2

Abstract

Background: Cigarette smoke is free radical that causing some pathological conditions such as inflammation, proteolysis, and oxidative stress. In previous studies, mangrove (Rhizophora apiculata) bark extract showed the potential effect as an antioxidant. Mangrove and mangrove associates are abundant plants that grow throughout Indonesian shorelines that have high pharmaceutical and food values. Objective: The purpose of this study is to explore the potential of Rhizophora apiculata bark extract in protecting pancreas of male white rat (Rattus novergicus) Sprague Dawley strain exposed to cigarette smoke. Methods: This research was an experimental study using a posttest-only control group design. Mangrove bark was extracted by using the maceration method. Cigarette smoke exposure was performed using an electric cigarette. Liver inflammation is assessed histopathologically. Results: Significant results (p <0.05) were found between the control and cigarette groups as well as the cigarette and bark extract + control groups. The results were not significant (p> 0.05) between the control and the bark extract + cigarette. Conclusion : The administration of mangrove bark extract has a potential to protect the damage of pancreatic male white rats (Rattus norvegicus) Sprague Dawley strains exposed to cigarette smoke
Ethanol extract of Bruguiera gymnorrhiza mangrove leaves and propolis activity on macroscopic healing of cuts in vivo Evi Kurniawaty; Shina Megaputri; Syazili Mustofa; Soraya Rahmanisa; Kholis Abdurachim Audah; Silvia Andriani
Acta Biochimica Indonesiana Vol. 5 No. 1 (2022): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.94

Abstract

Background: Bruguiera gymnorrhiza mangrove and propolis are often used as natural wound treatments. Its constituent is believed to promote wound healing. Objective: This study aims to explore the effect of topical administration of ethanol extract of Bruguiera gymnorrhiza mangrove leaves and propolis on wound healing activity. Methods: Twenty-four Sprague Dawley rats were randomly assigned to one of four treatment groups (n=6): aqua dest, standard wound medicine, ethanol extract of Bruguiera gymnorrhiza mangrove leaves, and propolis extract. Following the incision, treatment was given once a day for 14 days or until the wound healed. The cut area was observed by measuring the cut length using a ruler. Results: Standard wound medication took 9 days to promote healing, while the negative control (aqua dest) took 11.2 days, the ethanol extract of Bruguiera gymnorrhiza mangrove leaves took 7.3 days, and the propolis extract took 7.9 days. Conclusions: Topical administration of Bruguiera gymnorrhiza mangrove leaves ethanol extract and propolis had equal effects on the healing of wounds. Both are more effective than conventional wound ointments at healing cuts.
Co-Authors Anita Febrina Ari Wahyuni Arifaa Thalitha Z. Arifaa Thalitha Zuleikha Asep Sukohar Bainah Sari Dewi Charla Gutri Farmitali Della inike Putri Elza Wijaya Erlita Kusuma Wardani Hari Kaskoyo Hendri Busman Huzaimah Huzaimah Iffa Afiqa Khairani Irmanida Batubara Julkipli Julkipli Khairun Nisa Kholis Abdurachim Audah Kholis Abdurachim Audah Liana Sidharti Liana Sidharti Mira Kurnia Nadia Gustria Dini Natasya Hayatillah Nuning Nurcahyani Nuriah Nuriah Oktadoni Saputra Razethy Batubara Reni Zuraida S Rahmanisa Samsul Bakri Samsul Bakri Shina Megaputri Silvia Andriani Silvia Andriani Silvia Andriani Silvia Andriani Soraya Rahmanisa Soraya Rahmanisa Soraya Rahmanisa Suharyani Suharyani Syazili Mustofa T.A. Larasati Tiwuk Susantiningsih W Bahagia Winda Trijayanthi Utama, Winda Trijayanthi Yustika Pramudyawati