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All Journal Jurnal Pendidikan Sains Folia Medica Indonesiana Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan Jurnal Sport Science Kinestetik : Jurnal Ilmiah Pendidikan Jasmani JMM (Jurnal Masyarakat Mandiri) Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Jurnal Sporta Saintika JOSSAE (Journal of Sport Science and Education) Jurnal Maenpo : Jurnal Pendidikan Jasmani Kesehatan dan Rekreasi Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Patriot STRADA Jurnal Ilmiah Kesehatan KORSA
Sugiharto Sugiharto
Universitas Negeri Malang
Humanities Economics, Econometrics & Finance Education Health Professions Library & Information Science Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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MEDIASI LATIHAN ANGKAT BEBAN TERHADAP PENINGKATAN EKSPRESI PGC-1α PADA REMAJA PEREMPUAN PENDERITA OBESITAS Moh. Alfino Arisandi; Desiana Merawati; Sugiharto Sugiarto
KORSA: Jurnal Kajian Ilmu Keolahragaan dan Kesehatan Vol 2, No 1 (2023): Mei
Publisher : Program Studi Ilmu Keolahragaan

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Abstract

Peroxisome proliferator activated receptor-gamma coactivator 1 (PGC-1α) is closely related to metabolic status in obese patients. This study aims to analyze the response of lifting weights to increased levels of PGC-1α as a metabolic status in obese people. This study was a true experimental study with the randomized pretest-posttest control group design using 14 female adolescents aged 20-25, body mass index (BMI) 25-30 kg/m2, normal systolic blood pressure, normal resting heart rate, Percentage of body fat ≥ 30%, and divided into 2 groups randomly, namely the control group without intervention 7 subjects and the group given weight training intervention 6 subjects. PGC-1α levels were examined using the Enzyme Link Immunosorbent Assay (ELISA) kit (Cat.No.:E-EL-H6017; Elabscience, Inc., USA). Data analysis techniques using SPSS version 21.0. The results of the analysis of the average pretest and posttest PGC-1α levels in K1 (1.19 ± 0.89 vs 1.27 ± 0.65 ng/mL, p = 0.746), and K2 (1.07 ± 0.26 vs 2.60 ± 0.40 ng/mL, p = 0.000). It is recommended for future research using male and female subjects, so that the results of the study can be generalized to both sexes.
The Increase of Brain-Derived Neurotrophic Factor Expression after Moderate-Intensity Aerobic Exercise in Obese Women Rixco Gesang Gumelar; Sugiharto Sugiharto; Desiana Merawati; Agnieszka Magdalena Nowak; Adi Pranoto
Journal of Sport Science and Education Vol 9 No 1 (2024)
Publisher : Faculty of Sport and Health Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jossae.v9n1.p28-35

Abstract

Obesity is closely related to a decrease in brain-derived neurotrophic factor (BDNF) expression, which will pose a risk for metabolic disorders. Therefore, this study aims to prove the effect of moderate-intensity aerobic exercise on increasing BDNF expression in obese women. A total of sixteen obese women were selected based on predetermined criteria and were divided into 2 groups, namely the aerobic exercise group (AE) and the control group (CN). Aerobic exercise was carried out by running on a treadmill at moderate intensity (60-70 HRmax) for 40 minutes/session with a frequency of 5x/week for 2 weeks. Blood samples were taken twice before and after exercise intervention to see BDNF expression using the Enzyme-Linked Immunosorbent Assay (ELISA-kit) method. The results of the analysis showed differences in increase between the control group (1816.66 ± 689.48 vs. 1822.86 ± 467.87 pg/mL; p = 0.974) and the intervention group (2173.81 ± 705.89 vs. 3635.01 ± 699.71 pg/mL; p = 0.013). This shows that moderate-intensity aerobic exercise carried out for 2 weeks has proven effective in increasing BDNF expression in obese women.
Changes in Serum Betatrophin Levels in Obese Women after Two-Weeks of Moderate-intensity Aerobic Exercise Nabila Ainaya Mubasyiroh; Sugiharto Sugiharto; Desiana Merawati; Nur Ezza Fazleen Mohd Fathil; Purwo Sri Rejeki; Fikri Sasongko Widyatama; Adi Pranoto
Journal of Sport Science and Education Vol 9 No 1 (2024)
Publisher : Faculty of Sport and Health Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jossae.v9n1.p1-7

Abstract

Obesity is associated with increased betatrophin levels, which can lead to fat metabolism disorders. Increased levels of betatrophin may inhibit the performance of the lipoprotein lipase (LPL) enzyme, making it difficult for triglycerides (TG) in the blood to be converted into energy and causing excessive fat accumulation in adipose tissue. Physical exercise has been reported to increase energy expenditure in obesity. This study aims to determine changes in betatrophin in obese women after moderate-intensity aerobic exercise. A total of twenty obese women aged 20-30 years took part in the study. The participants were administered into two groups: control (K1) and moderate-intensity aerobic exercise (K2). Moderate-intensity aerobic exercise (60-70% HRmax) was performed five times a week for two weeks. Pretest and posttest betatrophin levels were measured using the Enzyme-Linked Immunosorbent Assay (ELISA) Kit method. Data were analyzed using a paired samples t-test with a significance level of p ≤ 0.05. The results showed the average pretest and posttest betatrophin levels in K1 (0.44±0.14 vs 0.44±0.13 ng/mL; p=0.894), and K2 (0.41±0.05 vs 0.31±0.03 ng/mL; p=0.000). According to the study's findings, moderate-intensity aerobic exercise (60-70% HRmax) performed five times per week for two weeks positively impacted alterations in betatrophin levels in obese women.
Co-Authors - Roesdiyanto Ach. Rasyad, Ach. Adi Pranoto Agnieszka Magdalena Nowak Angga Wahyu Setya Budi Arya Dwi Prastickho Deddy Whinata Kardiyanto Desiana Merawati Dwi Anggareksa Setyo Widarto Eko Hariyanto Febry Saputra Fikri Sasongko Widyatama Firly Imaniar Hartono Hartono Ido Nur Abdulloh Khumaira Marsyahidah Badu M. E. Winarno Moch Nasmay Lupita Moh Indra Kurnia Hadiputra Moh. Alfino Arisandi Muhammad Aliffajaruddin Alfani Muhammad Aufar Adfani Irawan Nabila Ainaya Mubasyiroh Naufal Firdaus Nur Ezza Fazleen Mohd Fathil Olivia Andiana Pinton Setya Mustafa Prayogi Dwina Angga Prayogi Dwina Angga Prima Suci Ibar Wati Ningrum Purwo Sri Rejeki Purwo Sri Rejeki Rias Gesang Kinanti Rixco Gesang Gumelar Sapto Adi Septyaningrum Putri Purwoto Slamet Yulianto Supriyadi Supriyadi Supriyono Supriyono Wawan Prio Kuncoro