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All Journal Biospecies Jurnal Biologi Udayana AL KAUNIYAH Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Jurnal Biologi Universitas Andalas Jurnal Riau Biologia Jurnal Ilmiah Pertanian Jurnal Biodjati Jurnal Biologi Tropis Biosaintifika: Journal of Biology & Biology Education Bio-Lectura Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal KALANDRA
Mayta Novaliza Isda
Jurusan Biologi FMIPA Universitas Riau, Kampus Bina Widya Panam, Pekanbaru, Riau, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Social Sciences

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Journal : Biosaintifika: Journal of Biology

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The Potential of Wild Mango Leaves from Sumatera as the Immunostimulant Agent Sinaga, Patar; Roza, Rodesia Mustika; Isda, Mayta Novaliza; Fitmawati, Fitmawati; Juliantari, Erwina; Saputra, Agus
Biosaintifika: Journal of Biology & Biology Education Vol 10, No 3 (2018): December 2018
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (740.186 KB) | DOI: 10.15294/biosaintifika.v10i3.16549

Abstract

Wild Mango from Sumatera is potentially new immunostimulant. It contains mangiferin, which is potentially become the immunostimulant candidate. This study aimed to prove the immunostimulatory effect of wild mango leaves extract on white rat peritoneum fluid induced by Staphylococcus aureus bacteria. The immunostimulatory effect was determined based on the activity and capacity of macrophage phagocytosis. This study used 54 male white rats about 130 g - 290 g. Based on the results,the highest phagocytosis activity of macrophage cells was found in ethanol extract of Mangga Hutan leaves dose 2 with a percentage of phagocytosis activity was 84%. The highest phagocytosis capacity of the macrophage cells was also found in ethanol extract of Mangga Hutan leaves dose 2 with an average phagocytic capacity of 171.67 from 50 active macrophages. Results of this study indicated that wild mango leaves from Sumatera has the potential immunostimulant activity. This indicates that the wild mango have the potential for therapeutic efficacy for the prevention of degenerative diseases caused by immune deficiencies.
Co-Authors Adil Azzahwantara Adjie, Agung Purnomo Afragenia Zelfira Agung Purnomo Adjie Alzira Salsabillah Anwar, Nurhayati Appriliya Destiyana Ariya Permata Asih Rahayu Ajeng Agesti Asri Ria Lestari Ayu Azhari Chica Ollivia Fibrianti Defila Yanti Desita Salbiah DESTI ZARLI MANDARI, DESTI ZARLI Dewi, Reza Puspita Dhini Yulianti Diana Agriani Diandra Prudentia Dyah Iriani EFENDI, RANNY ARIESTA Elli Indriana Putri Elsya Desviyanti Elvianis Elvianis Ennie Chahyadi ERWINA JULIANTARI, ERWINA Fajar Nugraha Febby Ika Desyana Fitmawati Fitmawati Fitmawati Fitmawati Fitmawati Fitmawati Fitmawati Fitmawati Fitria Elysye Ningrum Fransisca Elvarina Hariono, Eko Haris Gunawan Ikhwan Taufik Ilahi, Rizky Nanda Kurnia Ismu Sodaqti Isra Fariza KHAIRIJON, KHAIRIJON Lailani Sabrina Laura Aprilia Ayu Kusuma Wahyu Priyadika M. Athallah Dzikri Alhady M. Rizqy Pratama Syah Marlina Agustina Sitinjak Maulana Ishak Maya Sari Meutia Hanum Meyla Suhendra Mimi Safitri Muhammad Asyraf Muhammad Tamyis Lutfi Hakim Nadia Kristina Najmi Fadhila Nithami Nery Sofiyanti Nia Ivanka Noto Prasetio Nurhafidha Ramadhani Nurhayati Anwar Oriza Athalia Ronald Pangeran Saud Fransisco Putri Maisarah Qintara Sahira Rafi Shadiq Alvi Rahmi Fitri Rana, Syafia Diang Ranny Wirmasari Rasyidah Ulfa Reza Puspita Dewi Riche Afrilla Riski Saputra Rizal Noor Rodesia Mustika Roza Rosmaina Rosmaina Saputra, Agus Sarah Novita Sari Umayah, Sari Savanah Zahra Sinaga, Patar Siti Fatonah Siti Fatonah Siti Fatonah SRI CAHYATI, SRI Surjawati Surjawati Syafia Diang Rana syafroni Pranata Syahrul M. Tirtha Juliana Titrawani Titrawani Vina Dwi Amanda Wahyu Lestari Wahyu Lestari Wulan refolla Yana Lisa Warni Yulia Rahmi