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All Journal Jurnal Surya Medika BIOEDUSCIENCE Jurnal Pengabdian Al-Ikhlas Journal of Engineering, Technology, and Applied Science (JETAS) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Journal of Pharmaceutical Care and Sciences Bioscientiae, Jurnal ilmu ilmu Biologi Innovative: Journal Of Social Science Research Sains Medisina Jurnal Farmasi SYIFA
Putri Vidiasari Darsono
Universitas Sari Mulia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

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AKTIVITAS ANTIBAKTERI EKSTRAK DADANGKAK (Hydrolea spinosa) TERHADAP BAKTERI Bacillus subtilis, Staphylococcus aureus DAN Escherichia coli Putri Vidiasari Darsono; M. Fajriannor T. M.
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.889 KB) | DOI: 10.36387/jiis.v5i1.398

Abstract

Hydrolea spinosa are one of the plants that grow in swamp habitat. This plant is used by the loksado hill dayak community in the area Hulu Sungai Selatan as a cure for malaria, coughing up blood, medicine for sores and ulcers and mosquito repellent. The phytochemical content of H. spinosa leaves include tannins, steroids, flavonoids, and alkaloids. Bacillus subtilis, Staphylococcus aureus is gram positive bacteria while Escherichia coli is gram negative bacteria. This study aims to determine the Antibacterial Potential of Dadangkak Ethanol Extract (Hydrolea spinosa) Against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli as local plants in South Kalimantan. The method used is disk diffusion, the stages of this research are starting from sample preparation, extraction, antibacterial screening, sterilization and media making, rejuvenation and making of bacterial suspensions, making variable concentration stock, and antibacterial test. Positive control using Amoxicillin 25 mcg and negative control using 20% ​​DMSO. Based on the results of the average inhibition zone of ethanol extract of dadangkak leaves on Bacillus subtilis with a concentration of 100 mg / ml, 300 mg / ml, 500mg / ml which is 4.3 mm, 4 mm, 5 mm, in Staphylococcus aureus with a concentration of 100 mg / ml, 300 mg / ml, 500mg / ml are 3mm, 4.6mm, 6.3mm while Escherichia coli with a concentration of 100 mg / ml, 300 mg / ml, 500mg / ml are 2.3mm, 3mm, 3.3mm. This shows that dadangkak leaf extract has antibacterial activity on gram-positive and gram-negative bacteria.
AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK BUAH MAHKOTA DEWA (Phaleria macrocarpa) DENGAN EKSTRAK HERBA MENIRAN HIJAU (Phyllantus niruri Linn.) TERHADAP PERTUMBUHAN Staphylococcus aureus Aulia Rahmah Triastanti; Putri Vidiasari Darsono; Siti Malahayati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 1 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i1.1101

Abstract

S.aureus infection was found to be around 5%-35% and cases of S.aureus resistance increased by 22.8% due to people being less compliant in treatment. One of the preventions of resistance is to return to the use of natural materials, especially plants that have been scientifically and empirically proven, one of which is Mahkota Dewa Fruit (Phaleria macrocarpa) and Green Meniran Herb (Phyllanthus niruri L.). The study was conducted using the True Experimental method using S.aureus bacteria. 3 treatment groups were used, namely positive control (Amoxicillin), negative control (DMSO), as well as Mahkota Dewa extract (Phaleria macrocarpa) and Green Meniran Extract (Phyllanthus niruri L.). Using the disc diffusion method and the dilution method to determine the magnitude of the inhibition zone, the value of MIC, and MBC. The extract of the Crown of God Fruit, The Green Meniran Herb, as well as the combination of the two extracts have successive bacterial inhibitory power with an average of 18.02 mm; 15.95 mm; and 15.09 mm against S.aureus. Testing by the dilution method obtained a KHM value of 60% (0.06g/mL) in each extract. KBM is not obtained in each extract.
Co-Authors Adriana Palimbo Ali Rakhman Hakim Anggrita Sari Aulia Rahmah Triastanti Dede Mahdiyah Dede Mahdiyah Dewi Pusparani Sinambela Dewi Pusparani Sinambela EKA RIA SAFITRI Estyqomah Estyqomah Fahrianti Fahrianti Fajriannor.TM, M. Fauzi Nurdin Hesty Wulandari I Ketut Purnama Putra Kunti Nastiti Lisnawati Lisnawati Mahdalena Mahdalena Mariatul Janah Melviani Melviani Mia Audina Mohamad Rafi Noval Noval Novalia Widiya Ningrum Novita Novita Nur Azizah Nur Syifa Rina Al Kahfi Rina Saputri Risky Amelia Rohama Rohama Rohama Rohama Romi Satria Saftia Aryzki Saftia Aryzki Siti Malahayati Siti Rahmawati Suwarni Suwarni Yulia Puteri Rahmida