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All Journal PHARMACON Majalah Obat Tradisional Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Jurnal Farmasi Sains dan Komunitas (JFSK) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) KACANEGARA Jurnal Pengabdian pada Masyarakat Jurnal Farmasi Indonesia Jurnal Dunia Farmasi Lombok Journal of Science Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Indonesian Journal of Pharmacy and Natural Product Prosiding SIMKESNAS Acta Holistica Pharmaciana Borneo Journal of Pharmacy

Agustina Nila Yuliawati

Sekolah Tinggi Farmasi Mahaganesha

Author-ID : 3846839

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Waktu Tunggu Pelayanan Resep di Depo Farmasi RS X Heny Dwi Arini; Agustina Nila Y.; Ari Suwastini
LOMBOK JOURNAL OF SCIENCE Vol 2 No 2 (2020): Lombok Journal of Science
Publisher : LOMBOK JOURNAL OF SCIENCE

Show Abstract | Download Original | Original Source | Check in Google Scholar

Salah satu indikator pelayanan farmasi yang diatur dalam standar pelayanan minimal (SPM) rumah sakit adalah waktu tunggu pelayanan obat jadi (non racikan) dan racikan. Menurut Peraturan Menteri Kesehatan Nomor 129 Tahun 2008 menyebutkan bahwa standar waktu tunggu pelayanan obat jadi adalah ≤30 menit, sedangkan untuk obat racikan adalah ≤60 menit. Penelitian ini bertujuan menggambarkan waktu tunggu pelayanan resep RS. X. Kemudian, membandingkan rata-rata waktu tunggu pelayanan resep dengan standard operating procedures (SOP) dan SPM rumah sakit, serta mengetahui faktor-faktor yang mempengaruhi waktu tunggu tersebut. Rancangan penelitian ini adalah cross sectional. Data penelitian dikumpulkan secara prospektif selama bulan Januari hingga Februari 2020. Sampel penelitian diambil secara acak dengan teknik simpe random sampling. Hasil penelitian menunjukan bahwa rata-rata waktu tunggu pelayanan resep non racikan adalah 21,2 menit dan obat racikan adalah 35,2 menit. Hal ini menunjukan bahwa rata-rata waktu tunggu pelayanan resep di depo farmasi rawat jalan RS.X telah sesuai dengan standar waktu tunggu pelayanan resep pada SPM, namun belum memenuhi SOP yang telah ditetapkan. Berdasarkan hasil uji one sample t-test, rata-rata waktu tunggu pelayanan resep berbeda bermakna dengan standar yang ditetapkan pada SOP dan SPM (p<0,05). Faktor-faktor yang mempengaruhi waktu tunggu pelayanan resep adalah jenis resep, jumlah sumber daya manusia (SDM), dan ketersediaan sarana prasarana

Formulation, Physical Quality Evaluation, and Antioxidant Activity of Body Butter of Ethanol Extract of Dragon Fruit (Hylocereus polyrhizus) Peel Agustina Nila Yuliawati; Kadek Duwi Cahyadi
Majalah Obat Tradisional Vol 25, No 3 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.51763

Dragon fruit (Hylocereus polyrhizus) has polyphenols as an antioxidant. It has known that the antioxidant content of dragon fruit peels was more than in the flesh, so it can be used as a source of natural antioxidants to replace synthetic antioxidants. The use of dragon fruit (Hylocereus polyrhizus) peel, especially as topical preparations in the form of body butter, was still rarely done, whereas dragon fruit peel as an antioxidant can be used as an active ingredient of cosmetics. The purpose of this study was to obtain the body butter formula of ethanol extract of dragon fruit (Hylocereus polyrhizus) peel and its physical quality evaluation, to know the antioxidant activity of ethanol extract of dragon fruit (Hylocereus polyrhizus) peel and its body butter. This research was an experimental study with the stages of research consisting of determination of native plants, making ethanol extract of dragon fruit (Hylocereus polyrhizus) peel, ensuring its activity antioxidant, performing body butter formulation procedures, carrying out physical quality evaluation such as organoleptic, homogeneity, pH, spread, protection, and adhesion ability, then antioxidant activity of its body butter. The result of this research showed that the ethanol extract of dragon fruit (Hylocereus polyrhizus) peel has a moderate level of antioxidant (Antioxidant Activity Index / AAI = 0,88). Furthermore, body butter which has contains antioxidant content of ethanol extract of dragon fruit (Hylocereus polyrhizus) peel as much as 0.5% has the best physical quality evaluation during storage and the highest AAI (0,54) among other body butter formulas.

STUDI EFEKTIVITAS REDUKSI KADAR FORMALIN PADA TAHU DENGAN PERENDAMAN AIR KUNYIT, AIR CUKA DAN AIR GARAM DALAM UPAYA PENYEDIAAN PANGAN AMAN Kadek Duwi Cahyadi; Agustina Nila Yuliawati; Gusti Ayu Dewi Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Tofu is one type of food made from soybeans which is widely consumed and even favored by the people of Indonesia. Based on research conducted in Manado City Health Market in 2017, 92.86% of white tofu sold in the market positively contains formalin. The high content of formalin will poison the body, cause stomach irritation, allergies, are carcinogenic (causing cancer) and are mutagenic (causing changes in cell function). In this research, a simple way to reduce formalin levels in tofu will be developed, namely immersion with turmeric water, vinegar, and salt water in formalin tofu samples (simulated samples). Optimization will be carried out on the soaking time to get the most optimal conditions to reduce the levels of formalin in tofu. The simulation sample was treated with turmeric water, vinegar and salt water for 15, 30, and 60 minutes and then tested with fehling and tollens reagents. Quantitative tests were also performed using UV-VIS spectrophotometry using chromatrophic acid reagents. Qualitative test results showed a decrease in formalin levels after soaking with turmeric water, vinegar and salt water for 60 minutes. Quantitative test results, immersion of turmeric water, vinegar and salt water for 60 minutes showed a decrease in formalin concentrations by 22.56%, 25.54% and 55.33%.

ANALISIS HUBUNGAN KEPATUHAN PENGOBATAN TERHADAP KONTROL GLIKEMIK PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI RAWAT JALAN RUMAH SAKIT Ã¢â‚¬Å“XÃ¢â‚¬Â BULELENG Pande Made Desy Ratnasari; I Gusti Ayu Indira Ardeliani; Agustina Nila Yuliawati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Type 2 Diabetes mellitus (T2DM) is a chronic disease that requires long-term treatment. There were problems related to antidiabetic medication adherence. Medication adherence directly affects patientÃ¢â‚¬â„¢s blood glucose level. The aim of this study was to analyze the association between the medication adherence and glycemic control among T2DM patients. The study was an observational with cross sectional design. Participants were 90 of T2DM outpatient at Ã¢â‚¬Å“XÃ¢â‚¬Â Buleleng General Hospital in July-September 2020. T2DM patients were included if age ?18 years, received the same antidiabetic for three months before the study, sign informed consent, fill out the questionnare and have fully medical record data. Patient are excluded if having weak general condition, were pregnant or breastfeeding. Data was collected through interview using the Probabilistic Medication Adherence Scale (ProMAS) questionnaire and based on patientÃ¢â‚¬â„¢s medical records. Data were analyzed with Kruskall-Wallis test. The results showed that most of patients were male (55.6%), aged 46-65 years (61.1%), had DM for 5-10 years (46.7%), elementary school (37.8%), with comordbidities (50%) and without complications (77.8%). Majority of patients (42.2%) showed moderate-high medication adherence and the majority of patients (66.7%) has uncontrolled blood glucose. Based on statistical tests, there was no association between medication adherence with patientÃ¢â‚¬â„¢s glycemic control (p=0.168). In dispite of it, finding showed that the level of medication adherence had an impact on glycemic control. Patients with high medication adherence showed better glycemic control.

Evaluasi Rasionalitas Penggunaan Antidiabetes Oral pada Pasien Diabetes Melitus Tipe 2 Rawat Inap di Rumah Sakit Nasional di Dili Putu Dian Marani Kurnianta; Gracia Isabel Baptista Soares; Anak Agung Ngurah Putra Riana Prasetya; Agustina Nila Yuliawati
Jurnal Farmasi Indonesia Vol 19 No 1 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i1.1338

Among several types of diabetes mellitus (DM), type-2 DM seemed to demonstrate the highest prevalence. Appropriate management in type-2 DM should follow rational use of antidiabetic agents to prevent any unfavorable impacts. In fact, due to the limited guidelines and medication resources, medication process for patients with type-2 DM has not been evaluated in Timor-Leste, especially at a national hospital in Dili. This was the first study which aimed to evaluate the use of oral antidiabetic agents (OAD) in hospitalized patients with type-2 DM at a national hospital, Dili Timor-Leste.This study was conducted retrospectively under cross-sectional design to describe the rational drug use evaluation based on indicators: right patient, right dose, right indication, right drug, and cautious to adverse events according to guideline from American Diabetes Association (2020). The included patients were diagnosed as type-2 DM, hospitalized during year 2020, and received OAD. Data were calculated (%) for each indicator of rational drug use.A total number of 83 hospitalized patients with type-2 DM at a national hospital in Dili had taken metformin (62.65%), gliclazide (12.15%), and combination of both metformin and gliclazide (22.89%), respectively. The evaluation results of OAD use according to ADA guideline comprised of right indication 100%, right patient 100%, right drug 72.28%, right dose 100%, and cautious to adverse events 93.7%. Despite favorable results in rational medication, enhancement for limitation of OAD use at a national hospital in Dili, Timor-Leste is compulsory.

Knowledge and Quality of Life in Type 2 Diabetes Mellitus Patients also its Related Factors Agustina Nila Yuliawati; Pande Made Desy Ratnasari; Putri Riski Rosalina
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 12, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.68631

Knowledge is important to control blood sugar and prevent complications, and subsequently have an impact on the quality of life (QOL) of type 2 diabetes mellitus (T2DM) patients as a response to their health. This study was aimed to determine the correlation between the level of knowledge and QOL in type 2 DM (T2DM) patients, as well as its related factors. This cross-sectional study was conducted in a Public Hospitals, Buleleng, Bali on September 2020. The inclusion criteria included T2DM outpatients aged ≥ 18-year-old, getting similar therapy for at least 3 months, filling out the questionnaire completely, being able to communicate well, and not in a pregnant/breastfeeding condition. Data were obtained by medical records, questionnaires DKQ-24 (knowledge) and EQ-5D-5L (QOL). The correlation between knowledge and QOL of T2DM patients and its related factors were analyzed using bivariate statistical tests. The findings of the 150 respondents showed that the majority of the patients were ≥ 60-year-old (53.3%), female (50.7%), first educational level (64%), not working (54%), low income (49.3%), >5 years of T2DM duration (44%), no complications (75.3%), taking 4-6 item medicines (66.7%), moderate knowledge level (70.7%) with QOL based on the utility score 0.892±0.154 and VAS 59.73±20.07. Statistical tests showed there was a significant correlation between knowledge and QOL based on utility value (p=0.01), but not with VAS value (p=0.165). These was reinforced by age which has a significant correlation with knowledge (p=0.042), also employment status and complications condition which have a significant correlation with QOL (p<0.05). Patients with a higher level of knowledge have a better QOL, despite different backgrounds.

Hubungan Kepatuhan Pengobatan Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik Disertai Hipertensi dan Menjalani Hemodialisis Agustina Nila Yuliawati; Pande Made Desy Ratnasari; I Gusti Ayu Santhi Pratiwi
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 12, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.69974

End-stage renal disease (ESRD) patients undergoing hemodialysis (HD) could experience several problems, then reducing their quality of life (QOL). Medication adherence (MA), including HD is very important to improve the patient's QOL. This study aimed to analyze the correlation between MA and QOL and its related factors in ESRD patients. This cross-sectional study was conducted at a Public Hospital, Buleleng, Bali in September 2020. A sample of 89 people was obtained by the purposive sampling technique. The inclusion criteria for this study were ESRD patients aged ≥18 years, undergoing HD, filling out the questionnaire completely, and being able to communicate well. Data were collected using ERSD-AQ and EQ-5D-5L questionnaire, also medication records. Data analysis were performed by Perason’s rank correlation, Spearman’s rho, Kendall’s tau-b/c, Mann-Whitney U, or Kruskal Wallis test (CI 95%). Findings showed that mostly respondents were <60 years old (66.3%), male (71.9%), less than high school educational (68.5%), not working (69.7%), lower income (55.1%), having an ESRD duration of <3 years (67.4%), taking ≤6 item medicines (96.6%), having a mean (±SD) QOL-based on a utility value of 0.779±0.172 and a visual analog scale (VAS) of 60.79±18.04. Hence, there was no significant correlation between MA and QOL, as well as patient characteristics to MA (p>0.05).). Otherwise, patients aged <60 years, high levels of education and income, as well as the number of drug items received, tend to have a better QOL (p<0.05).

Empowerment Program in Pesagi Village Community: Assistance in Compounding Innovative Peel-off Pain Reliever (UNO) Derived from Family Medicinal Plants Putu Dian Marani Kurnianta; Agustina Nila Yuliawati; I Komang Tri Musthika; Ni Kadek Ayu Sri Darma Putri; Ni Luh Putu Asra Dianita; Ni Putu Sudiasih; Ni Made Ayu Lestari; Ni Putu Arik Candra Wahyuni; I Putu Gede Hendra Wiarta; Powen Ester Jacqlien Fangidae; I Made Ngurah Arya Kresna Acharya Putra
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 8, No 3 (2022)
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

The abundance of family medicinal plants (TOGA) growing in the yards of the house can be utilized for one of the health products called boreh, a traditional medicine used from generation to generation by the Balinese. Boreh can be innovated into a peel-oﬀ preparation form that has some potential to increase public interest in traditional medicine. The contents of TOGA, such as ginger, turmeric, and galangal in the peel-oﬀ boreh preparation, may exhibit beneﬁcial eﬀects as a pain reliever. Therefore, the mentioned product can be used to overcome pain problems that are commonly found in the people of Pesagi Village. The ideas related to compounding certain innovative herbal preparations for overcoming health problems in Pesagi Village were carried out through community empowerment activities. A series of program activities took place during January-April 2022. The purpose of this community empowerment program was to provide training and assistance activities to the people of Pesagi Village in the practice of utilizing TOGA as an innovative boreh peel-oﬀ preparation, namely UNO, with empirical pain reliever properties. Guidance and assistance in compounding practice were based on the results of dosage formulation previously developed by the executive team in the School of Pharmacy Mahaganesha Laboratory. This empowerment program was executed through a learning-by-doing approach, integrated training, participatory practice, and guided mentoring by the executive team with knowledge and skills evaluation (pre-test and post-test, p=0.000, 95%). After the empowerment program, the community has been able to practice how to turn TOGA from the ground into a useful product. The innovative products in this empowerment program may oﬀer some potential beneﬁts to overcome certain health-related problems of the community in Pesagi Village, such as joint pain. The success of this program may encourage the sustainability of the program in the future.

Hubungan Pengetahuan dengan Kontrol Glikemik Pasien Diabetes Tipe 2 di Rumah Sakit Swasta Buleleng Bali Pande Made Desy Ratnasari; Agustina Nila Yuliawati; Mahadri Dhrik
Jurnal Dunia Farmasi Vol 6, No 3 (2022): Edisi Agustus
Publisher : Program Studi Farmasi, Fakultas Farmasi dan Kesehatan, Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdf.v6i3.5216

Pendahuluan: Kontrol glikemik merupakan kunci utama dalam menurunkan kejadian dan keparahan komplikasi serta mortalitas pada pasien diabetes melitus (DM) tipe 2. Pencapaian kontrol glikemik yang baik membutuhkan pengetahuan mengenai managemen terapi, penyakit dan perawatan diri. Tujuan: Penelitian bertujuan untuk menganalisis hubungan tingkat pengetahuan terhadap kontrol glikemik pasien DM tipe 2. Metode: Rancangan penelitian adalah cross-sectional yang dilaksanakan di salah satu Rumah Sakit Swasta Kabupaten Buleleng Bali pada bulan September 2020. Diperoleh 150 responden yang memenuhi kriteria inklusi diantaranya pasien DM tipe 2 rawat jalan periode Juli-September 2020, berusia ≥18 tahun, memperoleh antidiabetik yang sama minimal selama 3 bulan, serta bersedia mengisi kuesioner. Pasien dalam kondisi lemah, hamil atau menyusui tidak diikutsertakan dalam penelitian ini. Instrumen penelitian berupa lembar pengumpul data dan kuesioner pengetahuan Diabetes Knowledge Questionnaire 24 (DKQ-24). Kontrol glikemik menggunakan glukosa darah sewaktu (GDS) yang dikategorikan menjadi terkontrol dan tidak terkontrol. Hubungan tingkat pengetahuan dengan kontrol glikemik dianalisis menggunakan uji Kendall’s tau-c. Hasil: Mayoritas gambaran profil pasien berumur 40 tahun (94%), berjenis kelamin pria (51%), mengenyam pendidikan SD (34%), tidak bekerja (80,7%), mengidap DM ≤5 tahun (56%), mengidap komplikasi makrovaskuler dan penyakit penyerta hipertensi (46%) serta memperoleh antidiabetik kombinasi (74%). Sebesar 66% tingkat pengetahuan responden termasuk dalam kategori sedang dan 67,3% memiliki kontrol glikemik yang tidak terkontrol. Analisis hubungan tingkat pengetahuan dengan kontrol glikemik menunjukkan hasil yang tidak signifikan (p=0,954;r=-0,004). Kesimpulan: Pasien dengan tingkat pengetahuan yang lebih baik menunjukkan kontrol glikemik yang baik pula, maka dari itu peran edukasi di fasilitas kesehatan sangat penting untuk meningkatkan pengetahuan pasien.

Studi Pengendalian Persediaan pada Terapi Penyakit Diabetes Melitus Tipe 2 dengan Metode ABC Indeks Kritis Agustina Nila Yuliawati; Heny Dwi Arini; Pande Made Desy Ratnasari; Ni Made Dewi Jayanti; Dewa Ayu Putri Lestari Dewi
PHARMACON Vol. 11 No. 3 (2022): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Guna mendukung keberhasilan terapi penyakit diabetes melitus tipe 2 (DMT2), ketersediaan persediaan seperti obat penting untuk dikendalikan secara efektif dan efisien oleh pelayanan kesehatan seperti rumah sakit (RS) dan apotek. Penelitian ini bertujuan untuk mengkaji dan membandingkan pengendalian persediaan obat penyakit DMT2 menggunakan metode ABC indeks kritis pada suatu RS dan apotek yang ada di provinsi Bali. Jenis penelitian observasional dengan rancangan cross-sectional ini menggunakan data sekunder, meliputi data penjualan, investasi, harga jual, dan nilai kritis persediaan selama tahun 2019. Data tersebut diolah dan hasil indeks kritis (ik) pada tiap obat ditempatkan pada kelompok Aik, Bik, dan Cik. Hasil penelitian menunjukkan bahwa mayoritas persediaan obat antidiabetes pada apotek berada pada kelompok Cik (52,78%) dibandingkan kelompok Aik (30,56%), sedangkan pada RS, yaitu berada pada kelompok Aik dan Bik(38,10%). Pada praktik kefarmasian di RS dan apotek setempat, persediaan obat antidiabetes pada kelompok Aik seperti insulin dan metformin menjadi prioritas dalam perencanaannya.

Co-Authors Anak Agung Ngurah Putra Riana Prasetya Ari Suwastini Belinda Amalia Dewa Ayu Putri Lestari Dewi Elisabeth Oriana Jawa La Gracia Isabel Baptista Soares Gusti Ayu Dewi Lestari Heny Dwi Arini I Gusti Ayu Dwi Gangga Pratiwi I Gusti Ayu Indira Ardeliani I Gusti Ayu Indira Ardeliani I Gusti Ayu Santhi Pratiwi I Komang Tri Musthika I Made Ngurah Arya Kresna Acharya Putra I Putu Gede Hendra Wiarta Kadek Duwi Cahyadi Kadek Duwi Cahyadi Kadek Rani Widayanti Ketut Tia Pran Anggar Yani Mahadri Dhrik Ni Kadek Ayu Sri Darma Putri Ni Ketut Taman Ni Luh Putu Asra Dianita Ni Luh Putu Satria Maharani Ni Made Ayu Lestari Ni Made Dewi Jayanti Ni Putu Arik Candra Wahyuni Ni Putu Sudiasih Pande Made Desy Ratnasari Pande Made Desy Ratnasari Pande Made Desy Ratnasari Powen Ester Jacqlien Fangidae Putri Riski Rosalina Putu Dian Marani Kurnianta Repining Tiyas Sawiji

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