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All Journal Majalah Kedokteran Bandung Medula Juke Indonesian Journal of Cancer Jurnal Aplikasi Teknologi Pangan Jurnal Pengabdian Pada Masyarakat Jurnal Aplikasi Teknologi Pangan Bioscientia Medicina : Journal of Biomedicine and Translational Research Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Jurnal Mandala Pengabdian Masyarakat MAHESA : Malahayati Health Student Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research
Asep Sukohar
Department Of Pharmacology; Faculty Of Medicine; Universitas Lampung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Promosi Gizi dan Kesehatan bagi Wanita Hamil, Wanita Menyusui, dan Ibu Balita dalam Rangka Pencegahan Stunting di Kabupaten Lampung Tengah, Lampung Sutarto Sutarto; Asep Sukohar; Ratna Dewi Puspita Sari; Winda Trijayanthi; Sofyan Musabiq Wijaya
Jurnal Pengabdian Pada Masyarakat Vol 6 No 2 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202162.572

Abstract

PROMOTION OF NUTRITION AND HEALTH FOR PREGNANT WOMEN, BREASTFEEDING WOMEN, AND MOTHERS TODDLER IN THE CONTEXT OF STUNTING PREVENTION IN LAMPUNG TENGAH REGENCY, LAMPUNG. One of the determining factors for the success of health development is nutritional status. Health promotion efforts to increase awareness, willingness and ability of both individuals, families, groups and communities to live healthy and it is necessary to increase nutrition and health promotion for pregnant women and mothers under five. This activity was carried out in the context of preventing stunting in Tanggamus and Tanggamus Regencies which was carried out by the Service Team of the Faculty of Medicine, University of Lampung. Various health promotion efforts have been made to obtain optimal results through nutrition and health promotion. This activity aims to assist in the success of national health development through improving nutritional status, through increasing public knowledge about clean and healthy living habits in household settings, a balanced nutrition menu in preventing the incidence of stunting in the family. The methods used in carrying out this activity are lectures, focus group discussions, counseling on the portion of my plate, skill practice and food serving competitions for lokal products to improve nutrition for pregnant women and toddlers. Results of nutrition and health promotion activities for pregnant women and mothers under five in the context of preventing stunting in Central Lampung and Tanggamus districts. can assist in the success of national health development through improving nutritional status.
The Ethanolic Extract of Annonaceous sp. to Inhibit Vascular Endothelial Growth Factor (VEGF) as Anticancer Modalities Muhartono Muhartono; Asep Sukohar; Khairun Nisa; Ratna Dewi Puspita Sari; Suharyani; Arli Suryawinata
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 7 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i7.331

Abstract

Introduction: Cancer has become a major public health problem worldwide, with breast cancer is the most common cancer among women and one of the most important causes of death among them. Management of breast cancer have some adverse effects, with many factorx=s shiouln be considered to ordered the therapy. Use of chemotherapy will suppress cell proliferation and trigger apoptosis, but it cannot just focus on cancer cells only, but also would affected on other cells and cause. Objective: This study aim to analyze the inhibition effect of the Annonanceous sp. ethanolic extract to Vascular Endothelial Growth Factor (VEGF) on MCF-7 cells line Material and Methods: This study is an analytic experimental study used Randomized Complete Block Design (RCBD) with three repetitions. The extract was dissolved in 1 ml of DMSO with a concentration of 0.1%. Furthermore, dilution was made with a dose of 0 µg / ml (K); 25 µg / ml (P1); 50 µg / ml (P2); 100 µg / ml (P3); 200 µg / ml (P4). MCF-7 cells line were cultured used RPMI 1640 Medium with 80 – 90% confluent. The ethanolic extract of Annonaceous sp. were exposed to MCF-7 cells for 48 hours. Analyze of VEGF level use ELISA Methods with λ=405 nm. Results: The results of ELISA analyze shows that the ethanolic extract of Annonaceous sp. have potential effect to decreased of VEGF expression on sample with treatment on some concentration (p< 0,05). Conclusion: The ethanolic extract of Annonaceous sp. has shows the potential effect to decreased of VEGF level on MCF-7 cells line
Pemanfaatan Kulit Labu (Cucurbita Moschata Durch) Sebagai Minuman Herbal Pada Masyarakat Desa Negeri Katon-Provinsi Lampung Asep Sukohar; Andi Nafisah Tendri Adjeng; Nur Fitriana Muhammad Ali; Zulpakor Oktoba; Endah Ambarwati; Ihsanti Dwi Rahayu; Afriyani Afriyani; Ramadhan Triyandi
Jurnal Mandala Pengabdian Masyarakat Vol. 3 No. 2 (2022): Jurnal Mandala pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1420.645 KB) | DOI: 10.35311/jmpm.v3i2.101

Abstract

Antioksidan berperan penting dalam melindungi tubuh akibat efek radikal bebas yang menyebabkan menurunnya sistem imun, kanker, dan penyakit degeneratif seperti diabetes dan jantung. Salah satu sumber antioksidan alami adalah kulit Labu (Cucurbita moschata Durch) namun pemanfaatannya belum optimal dan masih sering dianggap limbah. Daerah yang banyak membudidayakan tanaman Labu adalah Desa Negeri Katon Kecamatan Negeri Katon Kabupaten Pesawaran, Provinsi Lampung. Pemanfaatan limbah kulit Labu belum optimal dikarenakan masyarakat tersebut belum memahami kandungan serta manfaat yang bisa diperoleh dari kulit Labu. Kegiatan ini merupakan salah satu bentuk pengabdian yang bertujuan untuk mengoptimalkan penggunaan kulit Labu sebagai sumber antioksidan adalah dengan memanfaatkannya menjadi produk sediaan teh. Melalui Pengabdian Kepada Masyarakat Desa Binaan (PKMDB) ini masyarakat dibimbing untuk meningkatkan pemanfaatan kulit Labu berupa pengetahuan dasar mengenai manfaat kulit labu sebagai antioksidan dalam menangkal radikal bebas, penyiapan bahan baku sampel kulit Labu. Pelaksanaan Kegiatan pengabdian kepada masyarakat menggunakan metode berupa memberi penyuluhan (ceramah dan tanya jawab), Pemberian questionare untuk mengukur efektifitas pengetahuan masyarakat sebelum dan setelah penyuluhan (pre dan post-test). Setelah pemberian materi dan pendampingan pembuatan sediaan teh Kulit Labu hasil kegiatan menunjukkan bahwa pengetahuan warga meningkat saat kembali mengisi kuesioner yang sama dan berbeda cukup besar dibandingkan sebelumnya. Sehingga melalui adaanya kegiatan pengabdian masyarakat ini dapat disimpulkan bahwa Kegiatan Pengabdian Masyarakat Di Desa Negeri Katon Kecamatan Negeri Katon Kabupaten Pesawaran mampu menambah wawasan dan memberi kontribusi mengenai manfaat dan pemanfaatan kulit Labu (Cucurbita moschata Durch).
Pengaruh FKTP (Fasilitas Kesehatan Tingkat Pertama), Kesehatan Lingkungan dan Morbiditas Penyakit Berbasis Lingkungan Terhadap IPM (Indeks Pembangunan Manusia) di Provinsi Lampung dengan Metode Structural Equation Modeling (SEM) Anita Febrina; Evi Kurniawaty; Bainah Sari Dewi; Samsul Bakri; Asep Sukohar; Hari Kaskoyo
MAHESA : Malahayati Health Student Journal Vol 4, No 5 (2024): Volume 4 Nomor 5 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i5.14381

Abstract

ABSTRACT In the JKN-KIS Program, FKTP acts as a gate keeper where FKTP is responsible for providing basic health services and functioning optimally according to its competency standards. The unequal availability of health facilities and very varied geographical conditions give rise to the potential for widening inequality in health utilization. The Human Development Index (HDI) is an important indicator for measuring success in efforts to build the quality of human life (society/population), one of the elements that make up the HDI is health. Good health is supported by health facilities and good environmental health conditions so that it can reduce environmental-based morbidity rates, so that people are able to carry out productive activities. This research uses a quantitative approach with a causal design which aims to explain how the FKTP variable influences changes in mediating variables, namely environmental health and morbidity and its influence on HDI. The research was conducted in the Lampung Province area. The data source used is secondary data from BPS (Central Statistics Agency) Lampung Province and the Lampung Province Health Service for 2018-2022. The data analysis method in this research uses a path analysis model to analyze the pattern of relationships between variables. Based on the research results, there is a significant influence of FKTP on environmental health and environmental-based disease morbidity, and there is a significant influence of FKTP, environmental health and environmental-based disease morbidity on HDI in Lampung Province. Meanwhile, there is no influence of environmental health on environmental-based disease morbidity. Thus, efforts to increase the HDI in Lampung Province as a measure of community welfare can be pursued by carrying out interventions to increase FKTP, environmental health and environmental-based disease control in a representative manner, where FKTP becomes central in health efforts in the region, so that a healthy community will be able to maximum productivity to improve their welfare. Keywords: FKTP, Environmental Health, Morbidity, IPM   ABSTRAK Dalam Program Jaminan Kesehatan Nasional (yang disebut bJKN-KIS), fasilitas Kesehatan tingkat pertama (FKTP) berperan sebagai gate keeper dimana FKTP bertanggungjawab sebagai pemberi pelayanan kesehatan dasar serta berfungsi optimal sesuai standar kompetensinya. Ketidakmerataan ketersediaan fasilitas kesehatan dan kondisi geografis yang sangat bervariasi, menimbulkan potensi melebarnya ketidakadilan pemanfaatan Kesehatan. Indeks Pembangunan Manusia (IPM) merupakan indikator penting untuk mengukur keberhasilan dalam upaya membangun kualitas hidup manusia (masyarakat/penduduk), salah satu unsur yang menyusun IPM adalah kesehatan. Kesehatan yang baik didukung dengan fasilitas kesehatan dan kondisi kesehatan lingkungan yang baik sehingga mampu menekan angka kesakitan berbasis lingkungan, sehingga masyarakat mampu beraktifitas secara produktif. Penelitian ini menggunakan pendekatan kuantitatif dengan desain kausal yang bertujuan untuk menjelaskan bagaimana variable FKTP mempengaruhi atas perubahan-perubahan dalam variabel mediasi, yaitu kesehatan lingkungan dan morbiditas hingga pengaruhnya pada IPM. Penelitian dilakukan di wilayah Provinsi Lampung. Sumber data yang digunakan adalah data sekunder dari BPS (Badan Pusat Statistik) Propinsi Lampung dan Dinas Kesehatan Propinsi Lampung Tahun 2018-2022. Metode analisis data dalam penelitian ini menggunakan model path analysis (analisis jalur) digunakan untuk menganalisis pola hubungan di antara variabel. Berdasarkan hasil penelitian ada pengaruh signifikan FKTP terhadap Kesehatan lingkungan dan morbiditas penyakit berbasis lingkungan, serta ada pengaruh signifikan FKTP, Kesehatan Lingkungan dan Morbiditas Penyakit berbasis Lingkungan terhadap IPM di Propinsi Lampung. Sementara itu, tidak ada pengaruh kesehatan lingkungan terhadap morbiditas penyakit berbasis lingkungan. Dengan demikian upaya peningkatkan IPM di Provinsi Lampung sebagai tolak ukur kesejahteraan masyarakat dapat diupayakan dengan melalukan intervensi pada peningkatan FKTP, kesehatan lingkungan dan pengendalian penyakit berbasis lingkungan secara refresentatif, dimana FKTP menjadi sentral dalam upaya-upaya kesehatan di wilayahnya, sehingga masyarakat yang sehat akan mampu berproduktifitas secara maksimal untuk meningkatkan kesejahteraannya. Kata Kunci: FKTP, Kesehatan Lingkungan, Morbiditas, IPM
Co-Authors Aditya Ramadhon Islami Sakaganta Afriyani Afriyani Andi Nafisah Anita Febrina Arief B Witarto Arli Suryawinata Arli Suryawinata Aulian Mediansyah Bainah Sari Dewi Endah Ambarwati Evi Kurniawaty Fibra Nurainy Hari Kaskoyo HENING HERAWATTI, HENING Herri S. Sastramihardja Ihsanti Dwi Rahayu Josi Jeremia Manurung Muhartono Muhartono Novita Herdiana Nur Fitriana Muhammad Ali Ramadhan Triyandi Ratna Dewi Puspita Sari Samsu Udayana Nurdin Samsul Bakri Sofyan Musabiq Wijaya Suharyani Sutarto Sutarto Winda Trijayanthi Utama, Winda Trijayanthi Yofita Sulfiana Sundari Zulpakor Oktoba