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All Journal Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan Journal of Food and Pharmaceutical Science Buletin Peternakan VALENSI Jurnal Ilmu Lingkungan AL KAUNIYAH Alchemy : Journal of Chemistry Proceeding International Conference on Global Resource Conservation Elkawnie EduChemia: Jurnal Kimia dan Pendidikan Eksplorium : Buletin Pusat Pengembangan Bahan Galian Nuklir Science and Technology Indonesia Shautut Tarbiyah Al-Kimia Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Jurnal Ecolab Sulolipu: Media Komunikasi Sivitas Akademika dan Masyarakat Jurnal Riset Sains dan Kimia Terapan al Kimiya : Jurnal Ilmu Kimia dan Terapan

La Ode Sumarlin

Chemistry Study Program, Syarif Hidayatullah State Islamic University, Indonesia

Author-ID : 392007

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Antidiabetic and Antidiarrheal Activity from Extract of Namnam (Cynometra Cauliflora) Leaf Sumarlin, La Ode; Suprayogi, Agik; Rahminiwati, Min; Satyaningtijas, Aryani; Sukandar, Dede; Nugraha, Ahmad Tjahja; Amalia, Ika
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

In addition to decorate the yard, plant namnam (Cynometra cauliflora) turns out to have merit as an herbal remedy because it has biological activities such as antimicrobial, antioxidant, cytotoxic, antiviral, anti-inflammatory, antitumor and antidiabetic. It is study will add to scientific information about plants Namnam the potential to be developed as a functional food and natural herbal remedies in particular as antidiabetic agents and antidiarrheal. Ability as an antidiabetic agent tested by the ability of plants Namnam inhibit Î±-amylase. Meanwhile, antidiarrheal activity will be tested against the isolated rabbit intestine recorded on kymograph. The analysis showed that the leaf extract of plant Namnam (C. cauliflora) at a concentration of 100 mg/mL, 250 mg/mL and 300 mg/mL each is able to inhibit Î±-amylase activity by 20.68%; 70.24% and 72.59% and IC50 of 200.67 Â± 0.53 mg/mL. The study also showed that the sample tested has the ability to decrease the activity of isolated rabbit intestine in the pattern described in kymograph. Thus the plant leaves Namnam (C. cauliflora) potential to be developed as antidibetes agent and antidiarrheal.Â This may partially explain the use in traditional medicine for the treatment of diarrhea. These results support their use in folk medicine.Keywords: Antidiabetic, antidiarrheal, Â Cynometra cauliflora, Namnam

Differentiation of Bovine and Porcine Gelatin Based on Spectroscopic and Electrophoretic Analysis Hermanto, Sandra; Sumarlin, La Ode; Fatimah, Widya
Journal of Food and Pharmaceutical Sciences Vol 1, No 3 (2013): J. Food Pharm. Sci (September-December)
Publisher : Fakultas Farmasi, Universitas Gadjah Mada

This study was conducted to explore the differentiation of bovine and porcine gelatins before and after pepsin hydrolysis based on peptide pattern from spectroscopic and electrophoretic analysis due to development of the halal food products analysis. In this study, pepsin (EC 3.4.23.1)Â was used to hydrolyze the two sources of gelatin with consideration to its ability to digest up to 20% of ingested amide bonds by cleaving preferentially after the N-terminal of aromatic amino acids such as phenylalanine, tryptophan, and tyrosine. In this study, we expect to produce the fragment of gelatins with differentiation in relative molecular weights. Gelatins fragments then analyzed by UV-Vis and FTIR spectroscopy to characterize the functional groups on each source of gelatins, followed by SDS-PAGE (Sodium Duodecylsulphate Polyacrylamide Gel Electrophoresis) to identify the molecular weight of the resulting fragments. In UV-Vis spectroscopy, both gelatin source before and after hydrolysis had different absorbance at 229 nm and 240 nm showing the proportion of C=O amida and differences in two-dimensional conformation of the peptide. In terms of FTIR spectra, both gelatin have wavenumber at 3300-3400 cm-1 (NH stretching), 1600 cm-1 (C=O stretching, amida), 1500 cm-1 (C-N stretching), and at 620-767 cm-1 (OCN bending). This indicates that the relative amino acid compositions from two sources of gelatins were relatively different. In contrast, SDS-PAGE analysis does not give a real differentiation, except for porcine gelatin, that fragments which on 2 hour incubation show two peptide fragments with molecular sizes below 36,2 kDa and 28.6 kDa.

Aktivitas Antibakteri Kapang Endofit dari Tanaman Kina (Cinchona calisaya Wedd.) Zakiyah, Alfida; Radiastuti, Nani; Sumarlin, La Ode
Al-Kauniyah: Jurnal Biologi Vol 8, No 2 (2015): Al-Kauniyah Jurnal Biologi
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Endophytic microorganisms are microorganisms that live in the tissues of plant organ and not harm its host. One of them is the endophytic fungi. Endophytic fungi could produce the same compound as the host plant. The Plants produced alkaloids quinine that could potentially inhibit the bacteria Staphylococcus aureus and Escherichia coli. This study aims to test the potential of endophytic fungi produced quinine as an antibacterial. The method used to test the antibacterial is a paper disc diffusion. Results of the analysis of data using one-way ANOVA showed that there are significant differences zona between the diametre of inhibitory of the endophytic fungi extract. Endophytic fungi M16 and M33 produced the greatest inhibition zone against Staphylococcus aureus and Escherichia coli 14.9 mm and 9.2 mm respectively.

Identifikasi Potensi Enzim Lipase dan Selulase pada Sampah Kulit Buah Hasil Fermentasi La Ode Sumarlin; Dikdik Mulyadi; . Suryatna; Yoga Asmara
Jurnal Ilmu Pertanian Indonesia Vol. 18 No. 3 (2013): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.721 KB)

Fermentation is one of bioconversion to produce profitable anaerobic microbes and to produce various enzymes. Lipases and cellulases are widely used enzymes so far. Cellulases play an important role in bioconversion of organic waste cellulosic materials to glucose, single cell proteins, animal feed, and ethanol. Lipases can also degrade fatty ester bond. Therefore, both enzymes are potential to be used in industry as well as in households. Fermentation of fruit peel waste is an attempt to produce cellulase and lipase that can be carried out in a simple way. Cellulase as says was performed using DNS (3.5-dinitrosalicylic acid) and acid-base titration for analysis of lipase using cooking oil as the substrate. The results showed that the highest cellulase activity was obtained from watermelon rind mixed with citrus fruit peel of 0.036 U/mL, and mixed of banana peel and citrus fruit, which was 0.035 U/mL. The optimum lipase activity was at 30 oC, pH 7, and reaction time of 60 minutes. The highest lipase activity (1.36 U/mL) was obtained from mixture of watermelon and orange rind. Thus, the fruit peel waste is potential to produce cellulase and lipase by fermentation .

Aktivitas Antikanker dan Antioksidan Madu di Pasaran Lokal Indonesia La Ode Sumarlin; Anna Muawanah; Prita Wardhani; . Masitoh
Jurnal Ilmu Pertanian Indonesia Vol. 19 No. 3 (2014): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1947.785 KB)

Scientists have reported that honey contains several chemicals which have the function of antibacterial, anti-inflammatory, analgesic, wound healing, anticancer, antioxidant and free radical scavenging activity. In this study focuses on exploring the honey in the local market with anticancer and antioxidant activity. Methods used include BSLT method for potential of anticancer and antioxidant to DPPH (1,1-difenil-2-pikrilhidrazin) method. In addition, using Fourier Transform Infra Red (FTIR) analysis to test the functional groups in the honey. The analysis showed that the samples of honey has potential as an anticancer and antioxidant. Prameters of LC50 values obtained by the method Brine Shrimp Lethaly Test (BSLT) the highest as anticancer found in honey from Bali with a value 1.50 ppm. While the IC50 value obtained from DPPH method showed that honey derived from Papua has the potential antioxidant with IC50 value 5453.75 ppm. The results of the FTIR analysis showed that all of samples have the same in main functional groups. These results also indicate that honey was in the local market (Indonesia) is very potential to be consumed for various purposes, mainly to improve health.

Potensi Limbah Padat Kelapa Sawit sebagai Antibrowning dan Repellent Aedes Aegypti La Ode Sumarlin; . Faturrahman; Sri Yadial Chalid
Jurnal Ilmu Pertanian Indonesia Vol. 24 No. 2 (2019): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

A research was conducted to study the potential of solid oil palm waste as an antibrowning and as a repellent of Aedes aegypt. The amount of oil palm waste is increasing along with the expansion of oil palm plantation. A prevention method is needed to overcome solid, liquid, and gaseous wastes of oil palm which pollute the environment. Cellulose, hemicellulose, and lignin contained in solid waste of oil palm can be anaerobically fermented naturally to produce garbage enzyme which can be used as an antibrowning and as a repellent of Aedes aegypt. Browning index and polyphenol level were tested with UV Vis spectrophotometry while repellent level was tested using Aedes aegypti mosquito and a formula applied to the skin. The result showed that the acidity level (pH) was between 3.54-3.15. The highest antibrowning properties were found in oil palm fiber (SKS) and palm oil cake (BKS) with a browning index value of 0.037 with a relative inhibition (antibrowning) of 78%. Meanwhile, the highest repellent properties toward Aedes aegypti was showed by the on palm empty fruit bunch (TKS) + oil palm fiber (SKS) with 79.76% effective rejection percentage. There fore, fermented oil palm waste has an antibrowning effect and a repellent Aedes aegypti mosquito.

BIOAKTIVITAS EKSTRAK METANOL DAUN NAMNAM SERTA KOMBINASINYA DENGAN MADU TRIGONA La Ode Sumarlin; Agik Suprayogi; Min Rahminiwati; Achmad Tjahja; Dede Sukandar
Jurnal Teknologi dan Industri Pangan Vol. 26 No. 2 (2015): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Namnam (Cynometra cauliflora L) and trigona honey are two natural ingredients that are potential to be developed in Indonesia. However, scientific evidence of its active compounds and bioactivity is still rarely found, particularly the combination of these two materials. Therefore, this research is to explore their active ingredients of combination of these two materials such as total phenolic, flavonoids, vitamin C and β-carotene and bioactive capabilities such as antioxidant activity and antibacterial activity. The analysis showed that antibacterial activity of methanol extract of Namnam leaves (EMDN) and trigona honey either in their sole form or combined form has antioxidant and antibacterial activity. The EMDN was more sensitive to Staphylococcus aureus (23.7±3.3 mm) than to Escherichia coli, while the Trigona honey (MT) more sensitive to Escherichia coli (32.6±4.4 mm) than Staphylococcus aureus (16.6±4.1 mm). Similarly, the combination of EMDN and MT was more sensitive to Escherichia coli (23±1.9 mm) than Staphylococcus aureus (17.6±2.6 mm). Analysis of the antioxidant activity also showed that EMDN provided the highest activity (IC50 0.0048±0.000 mg/mL), a combination EMDN and MT (IC50 0.0085±0.000 mg/mL) and MT (IC50 3.736±0.112 mg/mL). Moreover, this analysis also showed thatsole samples of MT and EMDN have total phenolic content, flavonoids, and vitamin C that were higher than the combination of MT and EMDN. However, the content of β-carotene in the combined form of MT and EMDN was higher. Thus trigona honey, methanol extract of leaves Namnam (Cynometra cauliflora L) in a single form or in a combination are potential to be utilized and developed as a source of antioxidants and antibacterial in the form of functional food.

Analisis Potensi Program Studi Kimia Menuju Akreditasi Internasional oleh Royal Society Of Chemistry (RSC) La Ode Sumarlin; Ade Candra; Nurhasni Nurhasni
Shautut Tarbiyah Vol 27, No 2 (2021): Pendekatan Transdisipliner dalam Pendidikan Islam di Era 4.0
Publisher : Institut Agama Islam Negeri (IAIN) Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31332/str.v27i2.2688

Industrial Revolution 4.0 (IR 4.0) telah memberikan dorongan baru untuk transformasi pendidikan. Oleh karena itu upaya setiap Perguruan Tinggi (PT) untuk meningkatkan kualitas programnya menjadi sangat penting sehingga tetap relevan dengan perubahan zaman yang makin menantang. Salah satu upaya untuk medapatkan pengakuan terhadap kualitas pengelolaan PT melalui proses akreditasi baik secara nasional maupun internasional. Lembaga akreditasi internasional yang spesifik untuk Program Studi (PS) Kimia adalah Royal Society of Chemistry (RSC). Oleh karena itu perlu identifikasi kesiapan PS Kimia Fakultas Sain dan Teknologi UIN Syarif Hidayatullah Jakarta menuju akreditasi RSC. Data yang diperoleh berasal dari data angket yang disebarkan, wawancara langsung, studi pustaka, assesment lapangan dan Focus Group Discution (FGD). Data diolah dari berbagai sumber tersebut dan dianalisis. Hasil menunjukkan bahwa kondisi PS kimia juga dalam mengikuti perkembangan revolusi industri 4.0 juga sangat kondusif baik dari sisi dukungan sumberdaya dengan kemampuan penggunaan teknologi informasi yang baik, kriteria akreditasi RSC pada beberapa kunci persyaratan utama telah dapat dicapai oleh PS Kimia, namun demikian perlu optimalisasi dalam beberapa faktor kunci lainnya khususnya aspek kurikulum dan Benchmarking. Namun perlu dilakukan lagi berbagai proses menuju akreditasi RSC seperti Identifikasi secara rinci beberapa aspek perbaikan kurikulum dan proses pembelajaran agar memenuhi kriteria akreditasi RSC, Evaluasi Belajar dan skill mahasiswa perlu mendapat perhatian khusus terutama dalam penerapan OBE (Output Base Education) serta Evaluasi praktikum secara menyeluruh sesuai standar RSC.

Penggunaan Biokompos dalam Bioremediasi Lahan Tercemar Limbah Minyak Bumi Barokah Aliyanta; La Ode Sumarlin; Ahmad Saepul Mujab
Jurnal Kimia Valensi JURNAL Valensi Volume 2, No. 3, November 2011
Publisher : Syarif Hidayatullah State Islamic University

Penelitian ini dilakukan untuk mengetahui efektifitas biokompos, rumput gajah dan kelompok mikroba yang efektif dalam bioremediasi lahan tercemar minyak bumi yang dilakukan dalam skala laboratorium, dan bahan tambahan yang digunakan urea sebagai sumber nitrogen. Pada penelitian ini dilakukan berdasarkan rasio C/N yaitu 15, 10, dan 5. Parameter uji yang dilakukan untuk mengetahui kondisi optimal yang dicapai pada remediasi terdiri atas pH, kadar air, kadar abu, dan kemampuan ikat air/water holding capacity (WHC). Hasilnya menunjukan degradasi TPH (Total Petroleum Hidrokarbon) sebesar 91,15% dengan komposisi medium (100 g berat kering lumpur minyak bumi, 100 g berat kering biokompos, 9 g urea, rasio C/N = 5) menggunakan perlakuan dari kombinasi rumput gajah, mikroorganisme, urea dan biokompos selama 35 hari. Faktor lingkungan yang menghasilkan kondisi optimal ini dicapai pada remediasi diperoleh melalui kondisi awal pH 8,25; kadar air 49,97%; WHC 101,64%; dan kadar abu 63,76% dan kondisi akhir pH 6,25; kadar air 55,04%; kadar abu 73,39%; dan WHC 124,11%. Penambahan kompos dan urea dapat meningkatkan efisiensi degradasi TPH dan diperoleh hubungan positif antara jumlah penambahan kompos dan urea terhadap tingkat degradasi TPH. Kata kunci : biokompos, bioremediasi, degradasi, WHC, TPH

Uji Aktivitas Antidiabetes Fraksi Etil Asetat Daun Pandan Wangi (P. amaryllifolius Roxb.) dengan Metode α-Glukosidase Dede Sukandar; La Ode Sumarlin; Hilyatuz Zahroh; Eka Rizki Amelia
Jurnal Kimia Valensi Jurnal Valensi Volume 2, No.5, November 2012
Publisher : Syarif Hidayatullah State Islamic University

Telah dilaporkan hasil penelitian untuk mengetahui aktivitas antidiabetes setiap fraksi dalam ekstrak etil asetat daun pandan wangi (Pandanus amaryllifolius Roxb.) secara in vitro menggunakan metode α-glukosidase. Ekstrak dibuat dengan cara maserasi menggunakan pelarut etil asetat dan pemisahan komponen kimia dengan kromatografi lapis tipis (KLT). Hasil KLT dengan fase gerak n-heksan:etil asetat (3:1) dan penambahan 3 tetes asam asetat glasial menghasilkan lima fraksi dengan Rf masing-masing sebesar 0,20; 0,30; 0,55; 0,60; dan 0,70. Fraksi 2 memiliki aktivitas antidiabetes tertinggi dengan nilai IC50 relatif 77,57 ppm.

Co-Authors . Faturrahman . Masitoh . Suryatna A.S. Satyaningtijas Achmad Tjachja Achmad Tjachja Nugraha Achmad Tjahja Ade Candra Agik Suprayogi Ahmad Fathoni Ahmad Fathoni Ahmad Saepul Mujab Ahmad Tjahja Nugraha, Ahmad Tjahja Alfida Zakiyah, Alfida Alfionita Octa Nur Zidni Andhi Vitaria Andriantoro Andriantoro Anna Muawanah Arif Sumantri Arif Sumantri Bagus Sediadi Bandol Utomo Barokah Aliyanta Dany Poltak Marisi Dede Sukandar Dikdik Mulyadi Dina Fransiska Eka Rizki Amelia Eka Rizki Amelia Ericka Putri Wijaya Farhan Riza Afandi Farida Ariyanti Fuady Hanief Hajar Hajar Hajar Hajar Hendrawati Hendrawati Hilyatuz Zahroh Hilyatuz Zahroh Ihya Sulthonuddin Iin Ana Rizqi Ika Amalia, Ika Jane Ratini Putri Lela Mukmillah Lia Pratiwi M. Iqbal Suryatama Manadzhir Mahalli Megga Ratnasari Pikoli Melina Hadera Meyliana Wulandari Meyliana Wulandari Meyliana Wulandari Min Rahminiwati Nadya Uswatun Hasanah Nani Radiastuti Nida Sopiah Nur Enita Nur Ernita Nur Ernita Nur Ernita Nurhasni, N. Nurul Amilia Nurul Amilia Prima Soheti Prita Wardhani Ratna Istianah Riana Octavia Rita Mukhtar S Hermanto Salih Muharam Sandra Hermanto Siti Nurbayti Sri Yadial Chalid Sri Yadial Chalid Suharyono Suharyono Syifa Fauziah Teguh Wahyono Tri Retno Dyah Larasati Widya Fatimah Yoga Asmara Yunesfi Syofyan Zakki R Mubarok

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