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All Journal MIMBAR (Jurnal Sosial dan Pembangunan) Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmiah Farmasi Farmasyifa Jurnal Riset Farmasi Bandung Conference Series: Pharmacy
Kiki Mulkiya Yuliawati
Farmasi, Universitas Islam Bandung
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences

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Penetapan Kadar Flavonoid Ekstrak Etanol Daun Sirih Merah (Piper Ornatum N.E.Br.) Giffar Abdiljabbar Najmudin; Yani Lukmayani; Kiki Mulkiya Yuliawati
Bandung Conference Series: Pharmacy Vol. 3 No. 2 (2023): Bandung Conference Series: Pharmacy
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsp.v3i2.8614

Abstract

Abstract. The red betel plant (Piper ornatum N.E.Br.) has been used empirically and has been shown to have various pharmacological activities. The red betel plant contains various chemical compounds, one of which is flavonoids. The purpose of this study was to determine the levels of red betel leaf flavonoid compounds expressed in QE (Quercetin equivalent). The extraction method used maceration with 96% ethanol as a solvent and the determination of flavonoid content of the ethanol extract of red betel leaves was carried out spectrophotometrically with AlCl3 reagent. The results of determining the levels of flavonoids showed levels of 4.07 mgQE/gram extract with flavonol type flavonoids. Abstrak. Tanaman sirih merah (Piper ornatum N.E.Br.) telah digunakan secara empiris dan terbukti memiliki berbagai macam aktivitas farmakologi. Tanaman sirih merah mengandung berbagai senyawa kimia, salah satunya flavonoid. Tujuan pada penelitian ini untuk menetapkan kadar senyawa flavonoid daun sirih merah yang dinyatakan dalam QE (Quercetin equivalent). Metode ekstraksi menggunakan maserasi dengan etanol 96% sebagai pelarut dan penetapan kadar flavonoid ekstrak etanol daun sirih merah dilakukan secara spektrofotometri dengan pereaksi AlCl3. Hasil penetapan kadar flavonoid menunjukkan kadar sebesar 4,07 mgQE/gram ekstrak dengan flavonoid jenis flavonol.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN KELOR (Moringa oleifera L.) TERHADAP BAKTERI Staphylococcus epidermidis Deva Nissyarah Effendi; Kiki Mulkiya Yuliawati; Vinda Maharani Patricia
Bandung Conference Series: Pharmacy Vol. 3 No. 2 (2023): Bandung Conference Series: Pharmacy
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstract. Moringa plants (Moringa oleifera L.) have many benefits, one of which is found in the leaves. Moringa leaves (Moringa oleifera L.) contain secondary metabolite compounds in the form of flavonoids, alkaloids, saponins and tannins. In addition, Moringa leaves (Moringa oleifera L.) are thought to inhibit bacteria. This study aims to determine the antibacterial activity of Moringa leaves ethanol extract of Moringa leaves (Moringa oleifera L.). The extract was made by maceration using 96% ethanol as solvent. Antibacterial testing in this study used the wells diffusion method with concentrations of 2%, 4%, 6%, 8% and 10% b/v. The results showed that the inhibition zone of moringa leaf ethanol extract was 4% on Staphylococcus epidermidis bacteria by 8.2 mm . So It can be concluded that ethanolic extract of Moringa leaves had the potential to inhibit Staphylococcus epidermidis. Abstrak. Tanaman kelor (Moringa oleifera L.) memiliki banyak manfaat, salah satunya terdapat pada bagian daunnya. Daun kelor (Moringa oleifera L.) mengandung senyawa metabolit sekunder berupa flavonoid, alkaloid, saponin dan tanin. Selain itu, daun kelor (Moringa oleifera L.) diduga dapat menghambat bakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak etanol daun kelor (Moringa oleifera L.). Ekstrak dibuat dengan metode maserasi menggunakan pelarut etanol 96%. Pengujian antibakteri pada penelitian ini menggunakan metode difusi sumuran dengan konsentrasi 2%, 4%, 6%, 8%, dan 10% b/v. Hasil penelitian menunjukkan bahwa zona hambat ekstrak etanol daun kelor konsentrasi 4% terhadap bakteri Staphylococcus epidermidis sebesar 8,2 mm. Sehingga dapat disimpulkan bahwa ekstrak etanol daun kelor memiliki potensi untuk menghambat Staphylococcus epidermidis
Co-Authors Aldi Elgiawan Andri Ryandi Anggrilina Fitria Atrie Cahya Ramdhani Bertha Rusdi Deva Nissyarah Effendi Eky Bagus Wahyudi Esti Rachmawati Sadiyah Fatia Asy-Syahidah Al-Haq Fika Nurul Hafidzoh Geofanny Mozataufika Giffar Abdiljabbar Najmudin Indra Topik Maulana Jihan Fadillah Jihan Hana Fauziah Laroyba Tresna Fauzi Livia Syafnir Miaranti Tia Azhariani Nisvia Azahra Aulya Reza Abdul Kodir Riski Solehati Rodhiatul Jurdillah Salma Azizah Salma Fadhilah Azhar Selyatul Amaliah Sri Nur Azizah Suwendar Suwendar Vinda Maharani Patricia Yani Lukmayani