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All Journal Jurnal Ilmiah Farmasi Indonesian Journal of Pharmaceutical Science and Technology JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Dinamisia: Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Kreativitas PKM PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Pharmacoscript Jurnal Ilmiah Farmako Bahari Lumbung Farmasi : Jurnal Ilmu Kefarmasian Borneo Journal Of Pharmascientech Jurnal Ilmiah Pharmacy Sains Medisina GEMASSIKA: Jurnal Pengabdian kepada Masyarakat
Hafiz Ramadhan
Fakultas Farmasi - Universitas Borneo Lestari
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

 1 
Identification of Essential Oils From The Bark of Balik Angin (Alphitonia Incana (Roxb.) Teijsm. & Binn. Ex Kurz) Tika Nurjanah; Hafiz Ramadhan; Nella Faradillah; Putri Indah Sayakti; Dyera Forestryana; Nafila Nafila
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 4, No. 1 (2022)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.42498

Abstract

One of the components that make up essential oils is phenolic compounds which are widely containedin the leaves and bark of the Balik Angin plant (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz).This study aimed to identify phenolic compounds and antioxidant activity of essential oils from thebark of the Balik Angin plant. The essential oils isolation using hydrodistillation and the compoundswere analyzed using gas chromatography-mass spectroscopy (GC-MS). Qualitatively antioxidantactivity test used thin layer chromatography (TLC) and quantitatively by measuring the absorbance of2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals residue that did not react against compounds reducer.The results showed the essential oils contain major compounds which are methyl salicylate followedby methyl palmitate, 2,2-Dimethyl-1,3-dioxane-4,6-dione, and methyl 12-acetoxyoleate. Qualitativetest results of antioxidant activity with TLC there were four yellow spots on a purple background. Thescavenging activity showed the essential oils had an IC50 of 229.056 ppm, while the gallic acid as acomparative standard obtained an IC50 of 0.618 ppm. The conclusion is the essential oils of BalikAngin bark that produces very weak antioxidant activity.
Comparison of Extraction Solvents Towards Anti-Propionibacterium acnes activity of Alphitonia incana (Roxb). Teijsm. & Binn. ex Kurz Leaves Hafiz Ramadhan; Rahmi Muthia; Sari Wahyunita; Dyera Forestryana; Sherly Mar'atu Soleha; Lihimi Lihimi
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.45897

Abstract

Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz locally known as Balik Angin in Borneo Island is one of the endemic plants that have the potential to be an alternative antibacterial agent. Balik Angin leaves contain secondary metabolites that have to play a role to inhibit the growth of Gram-positive bacteria. This study aimed to compare the different extraction solvents which are methanol and ethanol on the maceration of Balik Angin leaves in producing antibacterial activity against Propionibacterium acnes. The leaves were macerated using methanol and ethanol respectively. Antibacterial assay was carried out by the Well diffusion method. The results showed minimum inhibitory concentration (MIC) of ethanol extract which is 3.2% has a diameter of clear zone of 9.475±0.311 mm. Meanwhile, the methanolic extract with a similar MIC has a lower diameter of clear zone of 2.55±0.85 mm. The results correlate with the number of secondary metabolites groups that were identified based on phytochemical screening in ethanol extract containing alkaloid, phenolic, flavonoid, tannin, saponin, and phytosteroid, however, methanol extract not containing alkaloid. The conclusion of this study is ethanol solvent more effective to extract secondary metabolites from Balik Angin leaves compare to methanol solvent, so that can produce more powerful anti-Propionibacterium acnes activity.
Co-Authors Abdul Rauf Abdurrahman Sidiq Ahmad Ridha Cahaya Rahayu Yuliani Cast Torizellia Dea Permata Rezky Duratul Baidah Duratul Baidah Dyera Forestryana Dyera Forestryana Dyera Forestryana Dyera Forestryana Dyera Forestryana Eka Fitri Susiani Fitriyanti, Fitriyanti Haryoto Haryoto Kristina Anes Yuliana Kristina Anes Yuliana Lihimi Lihimi Lisa Andina M. Andi Chandra M. Fahrul Ricky NorHavid Mahfuzah Hidayati Muhammad Arsyad Muhtadi Muhtadi Nafila Nafila Nella Faradillah Novi Puji Lestari Novi Puji Lestari Putri Indah Sayakti Putri Indah Sayakti Putri Indah Sayakti Putri Indah Sayakti Rahmayanti Fitriah Rahmi Muthia Ratna Restapaty Revita Saputri Revita Saputri Rutbatul Ulya Sari Wahyunita Satrio Wibowo Rahmatullah Satrio Wibowo Rahmatullah Sherly Mar'atu Soleha Suranto Suranto Tika Nurjanah Vebruati Vebruati Vebruati Vebruati Wahyudin Bin Jamaludin Zelita Perdani Putri Zyrzasya Sofia Nara Arsyad