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All Journal Jurnal Ilmiah Farmasi PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Wahyudin Bin Jamaludin
Fakultas Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia
Agriculture, Biological Sciences & Forestry Economics, Econometrics & Finance Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Pemanfaatan Bahan Alam sebagai Sumber Daya Kosmetik untuk Perawatan di Kelurahan Sungai Tiung Kecamatan Cempaka Dyera Forestryana; Wahyudin Bin Jamaludin; Ratna Restapaty; Hafiz Ramadhan
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol 6 No 5 (2021): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v6i5.2064

Abstract

Today, many cosmetic products are unhealthy and un-quality. Nowadays, the lifestyle trend of "back to nature" is increasing where people's trust in active compounds of natural materials is relatively safer than synthetic chemical compounds. Therefore, creating healthy and quality products at affordable prices is the focus of the government. Cosmetics are ingredients or preparations intended for use on the outside of the human body (epidermis, hair, nails, lips, and outer genital organs) or teeth and mucous membranes of the mouth, especially to cleanse, scent, change the appearance, and or improve body odor or protect or maintain the body in good condition. The activities that will be carried out are a demonstration of the manufacture of cosmetics of natural materials by a team of lecturers to the community in The Village of Sungai Tiung, Cempaka, Banjarbaru to improve the quality of public health knowledge and insights towards the training of cosmetic natural materials so that people can use the natural ingredients around as cosmetics and have a selling value, such as rose water, masks, and body butter. So that the cosmetic natural ingredients have the potential to be developed into natural mask ingredients for the face. It is expected that residents can use coffee, green tea, rose petals, oats, and rice as natural cosmetic ingredients for treatment and can increase their economic value as a business opportunity.
FORMULASI & EVALUASI FISIK GRANUL EFFERVESCENT KOMBINASI EKSTRAK ETANOL 70% BUNGA ROSELLA (Hibiscus sabdariffa L.) & BUNGA TELANG (Clitoria ternatea L.) SEBAGAI ANTIOKSIDAN Wahyudin Bin Jamaludin; Nadia Masytoh; Eka Fitri Susiani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 1 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i1.1065

Abstract

Rosella (Hibiscus sabdariffa L.) and telang flower (Clitoria ternatea L.) contain anthocyanins which have antioxidant, so the researchers combined to use as effervescent granules. This study aims to determine the characteristics, and the antioxidant activity of effervescent granule combination of rosella and telang flower extract. Antioxidant activity testing using DPPH. The antioxidant activity of the combined thick extract was obtained ???????? 50 7.5 ppm, after that it was made into an effervescent granule preparation in 4 formulas. The resut show that all formulas had a characteristic taste of almost uniform color, dark turquoise. In all test formulas for water content, the results obtained are 1.68%-2.82%, compressibility index 11.641%-16%, angle of repose 31.2º-34.43º, flow time 6.25-6.83 seconds, dissolving time 208 -257 seconds and pH 6.2-6.6. The results of the antioxidant activity of effervescent granules revealed ???????? 50 of 62,628 ppm (strong).
Pengaruh Perbedaan Pelarut dan Optimasi Waktu Inkubasi Bakteri Propionibacterium acnes Terhadap Ekstrak Etanol 96% Umbi Bawang Dayak (Eleutherine americana Merr.) M. Andi Chandra; Didik Rio Pambudi; Fitriyanti; Siti Kholilah; Wahyudin Bin Jamaludin
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art7

Abstract

Background: Acne (acne vulgaris) is still a major health problem. Treatment with antibiotics raises problems in the form of resistance, irritation, and immune hypersensitivity. Alternatives derived from natural ingredients are needed to avoid these problems, namely Dayak onions.Objective: To find out the activity of the ethanol extract of onion bulbs in inhibiting the growth of P. acnes based on the variation of the incubation time duration of the bacteria as well as the solvent.Method: Phytochemical screening tests looked for alkaloids, flavonoids, phenols, steroids, tannins, and saponins. Testing of the extract’s ability to inhibit bacteria was carried out with variations in the incubation times (24 and 48 hours) and solvents, namely Na-CMC and DMSO. The bacteria growth inhibition test employed the well-diffusion method, and the resulting data was analyzed using SPSS software.Results: Dayak onion extract contains alkaloids, saponins, flavonoids, and triterpenoids. Na-CMC solvent obtained the highest inhibition ability of Dayak onion extract at a concentration of 40% with an inhibition value of 10.12±1.840mm (24 hours), and 11.575±1.694 mm (48 hours) while DMSO solvent showed the highest inhibition at a concentration of 20% with inhibition values of 15.48±1.198 mm (24 hours) and 15.91±1.625 mm (48 hours). Interpretation of the results of the Wilcoxon test based on ranking showed a positive difference at 48 hours of incubation.Conclusion: The optimal incubation time of P. acnes was 48 hours with dimethyl sulfoxide (DMSO) as the best solvent. Intisari Latar belakang: Jerawat (acne vulgaris) masih menjadi masalah kesehatan utama. Penannganan dengan antibiotik memunculkan masalah berupa resistensi, iritasi hingga imunohipersensitivitas. Diperlukan alternatif yang berasal dari bahan alam untuk menghindari masalah-masalah tersebut, yaitu bawang dayak (Eleutherine americana Merr.). Tujuan: mengetahui aktivitas ekstrak etanol umbi bawang Dayak dalam menghambat pertumbuhan P. acnes berdasar variasi lama waktu inkubasi bakteri P. acnes dan variasi pelarut.Metode: Pengujian skrining fitokimia meliputi uji alkaloid, flavonoid, triterpenoid, tanin dan saponin. Pengujian aktivitas ekstrak dalam menghambat bakteri dilakukan dengan variasi waktu inkubasi yaitu 24 jam dan 48 jam, serta penggunaan pelarut yang berbeda yaitu Na-CMC dan DMSO. Uji penghambatan bakteri menggunakan metode difusi sumuran dan dilanjutkan dengan analisis data menggunakan SPSS.Hasil: Ekstrak bawang dayak mengandung alkaloid, saponin, flavonoid dan triterpenoid. Pengujian menggunakan pelarut Na-CMC didapatkan kemampuan hambat esktrak bawang dayak tertinggi pada konenstrasi 40% dengan nilai penghambatan 10,12±1,840mm (inkubasi 24jam) dan 11,575±1,694mm (inkubasi 48jam) sedangkan dengan pelarut DMSO didapatkan daya hambat tertinggi pada konsentrasi 20% dengan nilai penghambatan 15,48 ±1,198mm (inkubasi 24jam) dan 15,91±1,625mm (inkubasi 48jam). Interpretasi hasil dari uji Wilcoxon berdasarkan peringkat, menunjukkan perbedaan yang positif pada inkubasi 48 jam. Kesimpulan: Berdasarkan hasil penelitian ini diperoleh waktu inkubasi optimal dari bakteri P. acnes adalah 48 jam dengan pelarut terbaik yang dapat digunakan adalah dimetil sulfoksida (DMSO).Kata kunci: Bawang Dayak, antibakteri, DMSO, Na-CMC, waktu inkubasi
Karakterisasi dan Penetapan Kadar Fenol Total Ekstrak Etanol 96% Umbi Bawang Dayak (Eleutherine bulbosa Urb.) Berdasarkan Variasi Waktu Tumbuh Tanaman Rahmi Muthia; Kartini; Wahyudin Bin Jamaludin; Lulu Damayanti
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art9

Abstract

Background: Bawang dayak (Eleutherine bulbosa Urb.) grows widely in Kalimantan. This plant can be used as a raw material for medicine and is known to contain phenolic compounds that have antibacterial, antioxidant, and anti-inflammatory properties. The quality of the raw material of a plant determines its pharmacological activity. This is, of course, related to the content of compounds or active substances. One factor that plays an important role is the age of harvest, which can affect the content of compounds both qualitatively and quantitatively.Objective: To determine the simplicia characterization and total phenol content in bulbs of bawang dayak extracted using 96% ethanol, which were harvested at the ages of 1, 2, and 3 months.Method: Bulbs of bawang dayak are used in the 1st, 2nd, and 3rd months with several testing stages, namely organoleptic tests, macroscopic tests, and microscopic tests. Further qualitative analysis used TLC with chloroform and methanol (8:2) as the mobile phases. In the quantitative test, we used a UV-Via spectrophotometer with the folin-ciocalteau reagent and the gallic acid comparison.Results: The TLC test showed a positive result for phenol, which was marked after being sprayed with 1% FeCl3, a black spot appeared. The results of the determination of total phenol content in the 1st, 2nd, and 3rd months, respectively, were 59.196 ± 0.057, 76.596 ± 0.057, and 60.63 ± 0.2 mg/g GAE. Conclusion: The data above shows that the highest total phenol content is in the second month. Intisari Latar belakang: Bawang dayak (Eleutherine bulbosa Urb.) tumbuh menyebar di wilayah Kalimantan. Tanaman ini dapat digunakan sebagai bahan baku obat dan diketahui mengandung senyawa fenol yang memiliki kemampuan sebagai antibakteri, antioksidan dan antiinflamasi. Kualitas bahan baku suatu tanaman sangat menentukan aktivitas farmakologinya. Hal ini tentunya berkaitan dengan kandungan senyawa atau zat aktif. Salah satu faktor yang berperan penting yaitu umur panen yang dapat mempengaruhi kandungan senyawa baik secara kualitatif maupun kuantitatif.Tujuan: Mengetahui karakterisasi simplisia dan kadar fenol total pada umbi bawang dayak yang diekstraksi menggunakan etanol 96% yang dipanen pada umur tanaman 1, 2 dan 3 bulan.Metode: Umbi bawang dayak yang digunakan bulan ke-1, 2 dan 3 dengan beberapa tahap pengujian yaitu uji organoleptis, uji makroskopis, serta uji mikroskopis. Selanjutnya analisis kualitatif menggunakan KLT dengan fase gerak kloroform: metanol (8:2). Pada uji kuantitatif menggunakan alat spektrofotometer UV-Vis dengan reagen folin-ciocalteau dan pembanding asam galat.Hasil: Uji KLT menunjukkan hasil positif fenol ditandai setelah disemprot dengan FeCl3 1% terdapat noda berwarna hitam. Hasil penetapan kadar fenol total bulan pertama, kedua dan ketiga berturut-turut yaitu 59,196 ± 0,057; 76,596 ± 0,057, dan 60,63 ± 0,2 mg/g GAE.Kesimpulan: Kandungan total fenol tertinggi pada ekstrak umbi bawang dayak terdapat pada bulan kedua.Kata kunci: Fenol, KLT, spektrofotometer UV-Vis
Co-Authors Didik Rio Pambudi Dyera Forestryana Eka Fitri Susiani Fitriyanti, Fitriyanti Hafiz Ramadhan Kartini Lulu Damayanti M. Andi Chandra Nadia Masytoh Rahmi Muthia Ratna Restapaty Siti Kholilah