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Journal of Pharmaceutical and Health Research

jharma
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Published by Forum Kerjasama Pendidikan TInggi

ISSN : - EISSN : 27210715 DOI : https://doi.org/10.47065/jharma.v3i1.1322

Core Subject : Health,

Health Professions Medicine & Pharmacology Nursing Public Health

Journal of Pharmaceutical and Health Research memiliki bidang kajian, yaitu: 1. Bidang Gizi Klinis 2. Bidang Gizi Masyarakat 3. Pangan dan Gizi 4. Inovasi Pangan 5. Hematologi 6. Parasitologi 7. Biokimia 8. Laboratorium Kesehatan 9. Teknologi Laboratorium 10. Farmakologi 11. Farmasi 12. Keperawatan Jiwa 13. Keperawatan Anak 14. Keperawatan Maternitas 15. Keperawatan Medikal Bedah 16. Keperawatan Keluarga 17. Keperawatan Komunitas 18. Kesehatan Masyarakat 19. Teknologi Kesehatan

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 125 Documents

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Pengaruh Pengetahuan dan Sikap Terhadap Kepatuhan Minum Obat Pada Penderita TB Paru Ardat Ardat
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Juni 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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One type of generative disease that has been infected for a long time amid Indonesian society, which attacks the productive age group and children and is the number one killer infectious disease. Non-compliance with taking the medication regularly for TB sufferers can hinder the achievement of cure rates. The magnitude and extent of the problems caused by pulmonary TB require all parties to be able to commit and cooperate in the prevention of pulmonary TB. The purpose of this study is to determine the influence of knowledge and attitudes towards adherence to taking medication. The research design is a Cross-Sectional Study with an observational approach. The sample in this study were 39 people with pulmonary TB data collection instruments using a questionnaire. Data analysis with Che-Square analysis. The results of the study found that knowledge and attitudes had an effect on the value of p = 0,0001 and attitude had an effect on the value of p = 0.004. The conclusion of adherence is strongly influenced by the behavior and habits of one of them is knowledge

Analisis Natrium Siklamat Dalam Minuman Tebu(Saccharum Officinarum, L) Secara Spektrofotometri Lidyawati Lidyawati; Rosa Mardiana; Dwi Putri Rejeki; Jauhari Jauhari
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Sodium Cyclamate is one type of sweetener that is permitted, although being allowed to use excess sodium cyclamate can lead to cancer formation. Long-term consumption of sodium cyclamate can lead to metabolism of sodium cyclamate into cyclohexilamine compounds. The purpose of this study was to determine how much sodium cyclamate is used, whether it exceeds the maximum limit of 500 mg / kg weight of the material that has been determined. The sample used was a sample of sugarcane juice sold in Darussalam, which was then examined at the Chemical Laboratory of UIN Ar-raniry and FKIP Kimia Unsyiah Banda Aceh. The analytical method used is quantitative analysis using the UV-vis spectrophotometry method to determine the sodium cyclamate level. The results showed that the 4 samples used were negative containing sodium cyclamate with the level of Sample I = -449.8 Sample 2 = -426.4 Sample 3 = -520.6 Sample 4 = -444.8.

Faktor–Faktor Yang Berpengaruh Terhadap Kejadian Asma Bronkial Pada Anak di Puskesmas Saitnihuta Kabupaten Humbanghasundutan Winta Winta; Fransiska Fransiska; Nova Nova
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

The prevalence of asthma in Indonesia above <1 year 1.1%, Asthma causes a loss of 16% of school days in children. To determine the factors that affect the incidence of bronchial asthma in children. Asthma is a condition in which the airway is narrowed due to hyperactivity to certain stimuli that cause inflammation. The research method used case control study method. The diagnosis of asthma is based on anamnesis, clinical signs, additional examination. The control group were children who were not found to have asthma based on anamnesis, clinical signs, additional examination by pediatricians. The data were analyzed by univariate, bivariate, and chi square test. The result of research of risk factors influencing the incidence of asthma are sex (OR = 8,25, 95% CI, 1,252-54,364; p = 0,028), pet ownership (OR = 30,65; 95% CI; 1,538-610; (OR = 19.27; 95% CI: 2,169-171,3; p = 0.008), family illness history (OR = 8,27; 95% CI; 1,505-45,434; p = 0.015), cigarette smoke (OR = 23,13; 95% CI; 4,141-129,2; p = <0.001). The probability of individuals for bronchial asthma with all risk factors was 46.51%. Risk factors that affect the incidence of bronchial asthma are gender, pet ownership, climate change, family history, cigarette smoke. Suggestion for the public to be vigilant if any occurrence of shortness of breath to immediately contact health officer for further management.

Aktivitas Antibakteri Sediaan Gel dari Fraksi Aktif Daun Sintrong (Crassocephalum Crepidioides (Benth) S Moore) Muharni Saputri; Vriezka Mierza
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Indonesia is a tropical country that allows bacteria to easily grow and develop, especially in the skin. The drugs used are very diverse, generally from corticosteroids, which have side effects. This encourages the need for research on antimicrobial drugs from natural ingredients such as herbs that have high potency and relatively low side effects. Sintrong plants (Crassocephalum crepidioides (Benth.) S. Moore) are found in Parmeraan Village, Dolok District, North Padang Lawas Regency, North Sumatra Province. This plant is thought to contain alkaloid compounds and tannins as antimicrobials. This research method is an experimental study with the maceration method of ethanol extract and fractionation of n-hexane, ethyl acetate, phytochemical screening, making topical gels 20%, 10%, and 5% with parameters of pH, homogeneity, viscosity, dispersibility and adhesion as well as Antibacterial test against pure cultured bacteria using agar diffusion method using metal buffer, the bacteria used were gram-positive bacteria (Staphylococcus aureus ATCC 29737) and gram-negative bacteria (Escherichia coli ATCC 10536). The results showed that the ethanol extract of Sintrong leaves can be formulated in the form of a gel. The results of the evaluation that have been carried out on the methanol extract gel of Sintrong leaves show that the preparation has met the gel requirements. The formula that has the best antibacterial activity is Formula 1 which provides an inhibitory diameter of 17.10 mm and 18.75 mm for Escherichia coli and Staphylococcus aureus bacteria.

Identifikasi Formalin Pada Ikan Segar di Pelabuhan Pendaratan Ikan Idi Rayeuk Kabupaten Aceh Timur Rosa Mardiana; Lidyawati Lidyawati; Muhammad Zulfikri
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Indonesia is the second largest country after China in terms of capture fisheries production. Capture fisheries production in Indonesia in 2016 reached 6.83 million tons with a value of Rp. 125.3 trillion. The abundant fishery potential causes the fish preservation process at the fishermen level to be constrained. The limited number of preservatives that are safe for food makes formaldehyde an alternative preservative. The use of formaldehyde in food can cause poisoning to the human body.In the formaldehyde test conducted by the Integrated Supervision Team of the Aceh Marine and Fisheries Service (DKP) in 2017 it was found that the practice of using formalin as a fish preservative was still used by some fishermen and fish traders in Indonesia. Aceh. This research was conducted to determine the sustainability of the practice of using formaldehyde by fishermen and traders by identifying the formalin content in tuna and mackerel in Idi Rayeuk Fish Landing Port, East Aceh Regency. The samples used in this study were 3 tuna and 3 mackerel fish taken randomly at the Idi Rayeuk Fish Landing Site, East Aceh. The results showed that all samples tested showed negative results or the fish did not contain formaldehyde. This shows that the public and fishermen's awareness of the dangers of formaldehyde is very good.

Formulasi Sediaan Krim Menggunakan Kolagen Tulang Itik Air (Anas platyrhynchos domesticus) Sebagai Anti Aging Sudewi Sudewi; Nilsya Febrika Zebua; Aulia Milda
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

The collagen content in the human body decreases with age. One solution to reduce these negative effects is the application of collagen in various cosmetic and medicinal products. In the bones contain a lot of collagen and one of them is found in the water duck bone that has not been treated and is the result of waste. This study aims to make an anti- aging cream preparation resep from water duck bone collagen that can eliminate wrinkles, blemishes, shrink pores and smooth the skin. This research uses an experimental method using water duck bone test material. Stages of research include extraction of collagen from water duck bone, collagen characterization by infra red spectrophotomenter, making anti- aging cream of water duck bone with concentrations of 1%, 1. 5%, 2. 5%, 3. 5%, formulation and evaluation of cream preparations and test the ability of preparations using a skin analyzer. The results showed that the water duck bone contained collagen at wave numbers 3280- 3380 cm- 1 and 1280- 1680 cm- 1 which indicated the presence of amine and amide groups. Water duck bone collagen can be formulated into cream preparations with the evaluation results of preparations are homogeneous, stable and non- irritating preparations with a pH range of 6. 1 to 6. 4. Test results from collagen cream preparations show that the higher the concentration of collagen added to the resep, the more it will show a significant increase in effect.

Uji Skrining Fitokimia Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea Batatas L.) Lidyawati Lidyawati; Sasmiati Farach Dita; Cut Melly Agustiany
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Purple sweet potato leaf (Ipomoea batatas L.) is one of the plants that has begun to be used as a traditional or herbal medicine. This study aims to determine the content of secondary metabolites from purple sweet potato leaves. This research was conducted at the Chemistry Laboratory, Faculty of Tarbiyah, State Islamic University of Ar-Raniry Banda Aceh with laboratory testing methods. Purple sweet potato leaves were extracted by maceration using 5 L 96% ethanol for 5 days and evaporated in a vacuum rotary evaporator to form a thick extract. Furthermore, phytochemical screening tests were carried out. The test results stated that purple sweet potato leaf extract contains Alkaloids (+++), Flavonoids (+), Tannins (+), Saponins (+), Terpenoids (+), and Steroids (+).

Formulasi Sediaan Sabun Padat Dari Ekstrak Kulit Pisang Awak (Musa Balbisiana) Secara Maserasi Rosa Mardiana; Yuniati Yuniati
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Indonesia is the largest producer of bananas, along with the high productivity of bananas, the amount of banana peel waste also increases. When harvesting bananas, banana peels, stems and leaves (about 80%) are only removed without further processing. This is what causes the potential for banana peel waste to be large enough so that it is necessary to overcome the banana peel so that it has good value. The content in banana peels include carbohydrates, protein, fat, calcium, iron, phosphorus, vitamins B, C and C. Banana peel also has a cellulose content of 14.4%, an abundant amount, especially from banana peels, can be used as an efficient product. The method used in this study used the maceration method where the banana peel extract (Musa balbisiana) was made in the form of solid soap. which is heated and then the application of oil which is directly reacted with an alkaline solution at a temperature of 50˚C, so that a soap base is obtained. The solid soap preparation tests carried out in this study were organoleptic tests, pH tests and foam stability tests. The results of the evaluation of the preparation showed that the soap preparation was solid, there was no change in shape and odor, and had a pH that was in accordance with the standards for skin.

Uji Efek Antifungi Ekstrak Daun Biduri (Calotropis Gigantea L.) Terhadap Pertumbuhan Jamur Trichophyton Mentagrophytes Safrida Safrida; Rosa Mardiana; Nurul Husna
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

The leaf of biduri (Calotropis gigantea L.) is one of the plants that can be used as antifungal. Biduri leaves are used as antifungals based on the chemicals contained in them such as tannins, flavonoid saponins and polyphenols. The fungus Trichophyton mentagrophytes can cause a skin disease characterized by the appearance of circular and scaly patches or small bubbles known as Tinea or ringworm. This fungus has a habitat (especially in tropical and wet climates) in soil, humans and animals. This study aims to determine the effectiveness of biduri leaf extract (Calotropis gigantea L.) in inhibiting the growth of the fungus Trichophyton mentagrophytes and to determine what is the optimal concentration of biduri leaf extract (Calotropis gigantea L.) to inhibit the growth of the fungus Trichophyton mentagrophytes. This research was carried out at the Microbiology Laboratory of the Tarbiyah Faculty of UIN Ar-Raniry and the Chemical Laboratory of the Chemical Science Faculty, Syiah Kuala University, Banda Aceh, from 26 April to 21 August 2018. Biduri leaves were extracted using the maceration method which were soaked for 5 days with 2 repetitions and evaporated with using a rotary evaporator to obtain extract as much as 30 ml blackish green and thick. Inhibition test against the fungus Trichophyton mentagrophtes was carried out using the disc diffusion method on Potato Dextrose Agar (PDA) media with concentrations of 20%, 35% and 50%. Ketoconazole antifungal was made in suspension form as a positive control and aquadest as a negative control. The results showed that the diameter of the inhibition zone obtained from biduri leaf extract at a concentration of 50% of 9.16 mm was included in the medium category, at a concentration of 35% of 8.66 mm was included in the medium category, 20% concentration of 8.16 mm was included. in the medium category, 11.83 mm of ketoconazole suspension was included in the strong category and 0 mm of aquadest which had no inhibitory power.

Formulasi dan Uji Aktivitas Sediaan Masker Gel Peel Off Ekstrak Etanol 70% Daun Rambutan (Nephelium Lappaceum L.) Terhadap Propionibacterium Acnes Rahmawida Putri; Jaka Supriyanta; Dwi Afriliyani Adhil
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Rambutan Leaves (Nephelium Lappaceum L.) one of the plants that contain, alkaloids, flavonoids, tannins and saponins have antibacterial activity against Propionibacterium acnes which is a bacterium that causes acne. Rambutan leaf extract can be formulated to facilitate its use, one of which is in the form of a gel such as a peel off mask. This study aims to determine the characteristics of peel off mask preparations and to determine the antibacterial activity of ethanol extract 70% rambutan leaves (Nephelium Lappaceum L.) Peel off gel mask preparations 70% ethanol extract rambutan leaves (Nephelium Lappaceum L.) formulated into 4 formulas with a variety of extract concentrations, namely F1 (0%), F2 (10%), F3 (15%), F4 (20%). Physical evaluation tests which include: organoleptic, homogeneity, pH, viscosity, dry time, spreadability, adhesion, and irritation. And the antibacterial activity test was carried out against Propionibacterium acnes bacteria using the well method. The results showed that the physical evaluation was said to be good to meet the requirements. Antibacterial test results of gel peel off mask preparation of 70% ethanol extract of rambutan leaves (Nephelium Lappaceum L.) showed the existence of antibacterial activity against Propionibacterium acnes bacteria inhibition was the best at the concentration of F4 (20%) with an average diameter of 10.03 mm. One way ANOVA analiysis result showed that there wewre significant differences in each formula group (p<0,05).

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Home Page

OAI Link

Editorial Team

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Reviewer

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Contact Name Mesran

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Journal Mail Official mesran.skom.mkom@gmail.com

Editorial Address Jalan sisingamangaraja No 338 Medan, Indonesia

Location Kota medan, Sumatera utara INDONESIA

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Contact Name
Mesran

Contact Email
mesran.skom.mkom@gmail.com

Phone
+6282370070808

Journal Mail Official
mesran.skom.mkom@gmail.com

Editorial Address
Jalan sisingamangaraja No 338 Medan, Indonesia

Location
Kota medan,

Sumatera utara

INDONESIA