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Journal of Pharmaceutical and Health Research
Published by Forum Kerjasama Pendidikan TInggi
ISSN : -     EISSN : 27210715     DOI : https://doi.org/10.47065/jharma.v3i1.1322
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Health Research memiliki bidang kajian, yaitu: 1. Bidang Gizi Klinis 2. Bidang Gizi Masyarakat 3. Pangan dan Gizi 4. Inovasi Pangan 5. Hematologi 6. Parasitologi 7. Biokimia 8. Laboratorium Kesehatan 9. Teknologi Laboratorium 10. Farmakologi 11. Farmasi 12. Keperawatan Jiwa 13. Keperawatan Anak 14. Keperawatan Maternitas 15. Keperawatan Medikal Bedah 16. Keperawatan Keluarga 17. Keperawatan Komunitas 18. Kesehatan Masyarakat 19. Teknologi Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 125 Documents
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Formulasi dan Evaluasi Fisik Sediaan Gel Antiseptik Tangan Dari Ekstrak Etanol 96% Daun Pandan Wangi (Pandanus Amaryllifolius Roxb) Siti Marina; Banu Kuncoro; Sofi Nurmay Stiani; Rahmawida Putri
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (322.168 KB) | DOI: 10.47065/jharma.v2i1.837

Abstract

Antiseptic serves to kill or inhibit the growth of bacteria that can cause the onset of disease. Antiseptics can be formulated with natural ingredients so that they are environmentally friendly. Pandan wangi leaf is a plant that is often used as a food additive leaves, as a green dye and aroma. Pandan fragrance is also one of the plants that can be used as antiseptic formulations because it has antibacterial activity and can be used as a topical preparation in the form of gels. The aim of this research is to know the difference of pandan wangi leaf extract concentration (Pandanus amaryllifolius Roxb.) Which has optimum physical properties evaluation. This research is an experimental research, maseration method used to get extract with 96% ethanol. The gel was formulated into four formulas with various extract concentrations of 10%, 20%, 30%, and 40%. Evaluation tests include: organoleptic, homogeneity, pH, dispersion, viscosity, stability, hedonic, irritation and hand antiseptic testing. The results showed that the concentration of extract had no effect on pH and homogeneity. Increased concentration of extract effect on the color change and aroma. The higher concentration of extract will be more concentrated also color. The result of stability inspection showed that texture change in F2 and aroma change in F3. A good gel preparation formula based on physical quality and hedonic test is a concentration formula of 10% (F1). Keywords: Pandanus amaryllifolius Roxb., Hand Antiseptic, Gel.
Aktivitas Antibakteri Ekstrak Etanol Daun Bandotan (Ageratum Conyzoides L.) Terhadap Bakteri Streptococcus Pyogenes Jovita Almira; Yusransyah Yusransyah; Banu Kuncoro; Rahmawida Putri; Nuriyatul Fhatonah
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.841

Abstract

The treatment of bacterial infectious diseases using a semi synthetic antibiotic can lead to resistance, so that the search is necessary to overcome it the ingredients of natural medicine from plants, one of them namely bandotan leaf extract (Ageratum conyzoides l.). This research aims to identify the chemical compounds contained in leaf bandotan and knowing his activity as antibacterial against Pseudomonas aeruginosa and s. pyogenes. The leaves are extracted in bandotan maceration using solvent ethanol 96%. The extract was tested using the method of antibacterial activity of sumuran and clear zones are measured that is formed using a caliper and triplo. The results of the identification of a compound leaf bandotan secondary metabolite showed a group of compounds alkaloids, saponins, tannins, flavonoids, phenolic, triterpenoid glycosides, steroids,. Based on a test of antibacterial activity against s. pyogenes with the concentration of 100%, 50%, 25%, 12.5%, 6.25% showed a clear zone on the concentration in a row with an average of 14.52 mm; 13.87 mm; 13.38 mm; 12.38 mm; 11.75 mm; 15.33 mm. While testing the antibacterial activity against Pseudomonas aeruginosa with the same concentrations did not show the presence of antibacterial activity of extracts of leaves of bandotan with no clear zone formation
Evaluation of Drug Use at Pasar Merah Public Health Center in Medan Ismedsyah Ismedsyah; Takarina Takarina
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.858

Abstract

Evaluation of drug use is one of the clinical pharmacy services at Public Health Center. Evaluation of the drugs use must refer to the indicators of drug use.This study aimed to determine the average number of drugs in each prescription, the percentage of prescribed generic drugs, the percentage of prescribed antibiotics, the percentage of injection, and the percentage of drugs prescribed from the DOEN (List of National Essential Medicines) at Pasar Merah Public Health Center Medan. This research was a retrospective descriptive study carried out by collecting data from the available documents as well as interviews with the head of Medan Pasar Merah Public Health Center and drug management officers.Through the research, it was found that the average number of drugs in each prescription was still high, not in accordance with the prescribed standards, the percentage of generic drugs prescribed was not good, the percentage of prescribed antibiotics was quite high, the percentage of injections prescribed did not meet the percentage indicator of injection prescription, and the percentage of drugs prescribed from the DOEN at Pasar Merah Medan Public Health Center was quite good. This study concludes that the use of drugs in Pasar Merah Medan Public Health Center has not met the indicator of drug use
Formulasi Sediaan Hand Body Lotion Menggunakan Ekstrak Etanol Daging Buah Kedondong (Spondias dulcis Soland. ex Forst. fil.) Sebagai Pelembab Kulit Sudewi Sudewi; Yessi Febriani; Siti Raudah; Ira Nofriani; Nilsya Febrika Zebua
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.861

Abstract

Kedondong fruit (Spondias dulcis Soland. Ex Forst. Fil.) Is a fruit plant originating from South and Southeast Asia and spread in tropical areas. Kedondong fruit contains vitamins A, B and C, carbohydrates, protein and fat. This study aims to determine the pulp of kedondong (Spondias dulcis Soland. Ex Forst. Fil.) In the form of ethanol extract which can be formulated into a hand body lotion which at certain concentrations can provide a moisturizing effect on the skin and is not irritating. This research was conducted using experimental methods, using the test material of the pulp of the kedondong fruit (Spondias dulcis Soland. Ex Forst. Fil.). The ethanol extract of kedondong pulp (Spondias dulcis Soland. Ex Forst. Fil.) Was obtained by maceration using 96% ethanol filter, then concentrated using a rotary evaporator. The preparation is formulated into a hand body lotion with a concentration of 0.5%, 1.5%, 2.5% and 3.5%, as well as a blank. Examination of the physical quality of the preparation includes, homogeneity test, pH test, emulsion type test, stability test, irritation test and effectiveness test of the preparation in moisturizing the skin and comparing with preparations on the market using the Skin Moisturer Checker (AramÒ) and statistical data processing was carried out using the SPSS 26.00 ANOVA method. The results showed that the pulp of kedondong (Spondias dulcis Soland. Ex Forst. Fil.) In the form of ethanol extract can be formulated into a hand body lotion, a homogeneous preparation with the type of oil-in-water emulsion (M / A), has a momentary pH range. After making 6,6-7,3 and pH after 12 weeks of storage 6,3-7,0, the effectiveness test of moisture preparation at a concentration of 3.5% (Formula E) gave moisture (32%) categorized as "moist" which was statistically showed a significant difference with the comparison results, the hand body lotion that was made did not irritate the skin.
Pemanfaatan Minyak Atsiri Daun Sirih (Piper Betle Linn) Sebagai Anti Nyamuk Deki Gunawan; Rina Kurniaty
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.862

Abstract

Betel leaf (Piper betle Linn) is a plant that is widely known by the people of Indonesia, contains phenolic compounds and their derivatives which reaches 30% in extracts and essential oils, and at a concentration of 100 ppm it can kill mosquito larvae based on insecticidal activity. This study aims to utilize betel leaf essential oil, which was obtained by steam distillation method in the form of a spray dosage form and to find out at what concentration the betel leaf essential oil can be used as an insect repellent. This research is a laboratory experiment, there are 3 formulas of mosquito repellent spray (F1, F2 and F3) with a concentration of 13%, 15%, and 17%. The tests carried out on the anti-mosquito spray preparation were organoleptic tests and tests the effectiveness of the preparations against ten adult mosquitoes. Anti-mosquito spray preparation with a concentration of 17% betel leaf essential oil which is more effective at repelling and killing mosquitoes. Further research can develop the use of betel leaf essential oil with variations in different concentrations, or in combination with other active ingredients as mosquito repellent
Formulasi Sediaan Lotion Dari Ekstrak Buah Alpukat (Persea Americana) dan Lidah Buaya (Aloe Vera) Untuk Kulit Kering Marlia Oktaviana; Dwi Putri Rejeki; Ria Ceriana; Rosa Mardiana; Sasmiati Farach Dita
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.896

Abstract

Skin care is needed so that the skin does not become dry, rough, and dull. The way to deal with dry skin is to use a scrub or use a moisturizer such as lotion. One of the active substances contained in lotion preparations is antioxidant compounds. Avocado and aloe vera extracts have antioxidant activity. Avocado and aloe vera have moisturizing benefits. In this study, both types of extracts were formulated into lotion preparations. Avocado and aloe vera extracts were made by maceration method using 70% ethanol as solvent. The extract was formulated with 3 variations, namely the control formula (F0), the avocado extract formula with a concentration of 5% (FI), and aloe vera with a concentration of 10% (F II). The lotion was tested for physical properties including pH, homogeneity, stability, spreadability and irritation tests. The results showed that the lotion containing avocado and aloe vera extracts with storage for two weeks was stable. Does not change shape, smell, color, and does not irritate the skin
The Evaluasi Penggunaan Antibiotik Pada Pasien Dispepsia Komplikasi Demam Tifoid di Rumkit Putri Hijau Medan 2018 Desy Natalia Siahaan; Burham Burham; Reny Ayu Zendrato
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.913

Abstract

Antibiotics are substances that are produced by microorganisms that live from fungi that can fight or can fight other types of microbes. The use of higher antibiotics can be used in the use of antibiotics that are not rational. This research aims to improve the quality and quality of antibiotic use in inpatients at Patients with dyspepsia and complications of typhoid fever at TK Hijau Putri II Hospital, Kesdam I / BB Medan in 2018.The study was conducted descriptive descriptive with cross sectional research design with retrospective data collection conducted during the 2018 period. Quantitative evaluation research used the DDD (Defined Daily Dose) method and qualitative evaluation using the Gyssens category.The results showed that of the 120 patients using antibiotics, the quality assessment of the Gyssens category obtained results of 90% category 0 (rational), 10% category IIIA (duration too long). Evaluation of the amount by the DDD method (Daily Dose Determined) obtained the use of antibiotics with a DDD value / 1000 patient-day the highest was the fluoroquinolone group (ciprofloxacin and levofloxacin) with 56.4%, while for ciprofloxacin used 1,213 DDD / 1000 Patient-day and for levofloxacin have 1,000 DDD / 1000 Patient-days. Antibiotics for the third generation cephalosporins (cefotasim and ceftriaxone) with 43.14%, while for cefotasim have 713 DDD / 1000 Patient-days and for ceftriaxone have 1,000 DDD / 1000 Patient-days.
Uji Daya Hambat Ekstrak Etanol Daun Inai (Lawsonia inermis L.) terhadap Pertumbuhan Staphylococcus aureus Sasmiati Farach Dita; Lidyawati Lidyawati; Mutiara Sampoerna
Journal of Pharmaceutical and Health Research Vol 2 No 3 (2021): Oktober 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.29 KB) | DOI: 10.47065/jharma.v2i3.982

Abstract

Henna leaves are often used as traditional medicine, including as an antibacterial. Henna leaves contain several active components including phenols and flavonoids which act as antibacterial. The purpose of this study was to determine antibacterial activity of ethanol extract of henna leaves (Lowsonia inermis L.) against Staphyloccocus aureus. This research was conducted using descriptive method. In this study, ethanol extract of henna leaf was made by maceration method. Ethanol extract of henna leaves was tested against Staphylococcus aureus on Nutrient Agar (NA) medium using well diffusion method with 3 extract concentrations, namely 40%, 50% and 90%, tetracycline as positive control and aquadest as negative control with 3 repetitions each. The results of this study showed that inhibition zone diameter of henna leaves extract at a concentration of 40% was 21.29 mm, at a concentration of 50% was 23.1 mm and at a concentration of 90% was 24.4 mm, positive control was 27.93 mm and negative control did not show inhibition zone. The inhibition zone for all concentrations belongs to strong inhibition category.
Hubungan Pengawas Minum Obat dan Tipe Dukungan Keluarga Terhadap Kepatuhan Minum Obat Pasien Tuberkulosis Paru di Kota Banda Aceh Zulheri Zulheri; Fadli Syahputra; Lidyawati Lidyawati
Journal of Pharmaceutical and Health Research Vol 2 No 3 (2021): Oktober 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.021 KB) | DOI: 10.47065/jharma.v2i3.983

Abstract

Banda Aceh City is the capital of Aceh Province with the highest number of lung tuberculosis cases. This can be seen from the increase in the incidence of pulmonary tuberculosis in Banda Aceh City. The purpose of this study was to determine the relationship between the role of PMO and family support with pulmonary anti tuberculosis (OAT) drugsThis type of research is analytic descriptive with Cross Sectional Design and the object of research is 128 people with pulmonary TB in Banda Aceh City. The study was conducted for 3 months from August-November 2018 located in all Puskesmas working areas of the Banda Aceh City Health Office data analysis using logistic regression tests. Results PMO supervision, 57.8% received instrumental support, 53.1% received information support, 56.2% received valuation support, 64.0% received emotional support, 63.2% received spiritual support, 50.7% received financial support. statistical results obtained there is a PMO relationship (OR = 18.5 P-Value = 0,000) there is information support (OR = 5.4, P-value = 0.002), there is emotional support (OR = 3.54, P-Value = 0.027), there is support financial (OR = 0 .22, P-Value = 0.018), no instrumental support (OR = 2.5, P-Value = 0.050), no valuation support (OR = 1.22, P-Value = 0.664), no support spiritual (OR = 0.55, P-Value = 0.247)
Hypoglycemic Effect of Lesser Yam (DioscoreahispidaDennst) Extract on Hyperglycemic Rats in Postprandial Condition Ari Yuniastuti; Retno Sri Iswari; R Susanti; Yanuarita Tursinawati
Journal of Pharmaceutical and Health Research Vol 2 No 3 (2021): Oktober 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.009 KB) | DOI: 10.47065/jharma.v2i3.1085

Abstract

Hyperglycemia is a condition when the blood glucose levels exceed normal levels. Hyperglycemia can lead to the occurrence of Diabetes Mellitus (DM). The use of natural ingridients in lowering blood glucose levels has been carried out. However, studies on the benefits of lesser yam (Dioscorea esculenta) in reducing blood glucose levels have never been reported. This research aims to analyze the effect of administration lesser yam extract to hyperglycemic rats. Data were collected using experimental laboratoris pre-post test randomized design. Data were analysed using analysis of variance one way statistical test and advanced Tukey. Lesser yam contains Inulin as PLA (Water Soluble Polysaccharide) which serves to inhibit gastric emptying thus it can help manage a diet of people with hyperglycemic. The results obtained by the control group (not given treatment) shows no change in fasting blood glucose levels intesting as well as post prandial. The administration of lesser yam extract affects blood glucose levels to decreased in hyperglycemic rats in all groups. Significant decrease occurs in the testing conditions of first, second and third day post prandial group. The decrease is caused by the influence of the extracts after 2 hours of administration. Lesser yam (DioscoreahispidaDennst) is capable of lowering blood glucose levels of hyperglycemic rats in post prandial condition.

Page 3 of 13 | Total Record : 125

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