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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 14 Documents
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Search results for , issue "Vol 2 No 2 (2019)" : 14 Documents clear
UJI AKTIVITAS ANTIKOLESTEROL HASIL FERMENTASI ANGKAK PADA TIKUS GALUR Sprague dawley Abdul Rahman Wahid; Armiyatin Damayanti; Alvi Kusuma Wardani
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.296

Abstract

Hypercholesterolemia is a condition in which the levels of cholesterol in the blood increases and decreases in HDL cholesterol levels below the normal range. Low levels of HDL cholesterol and high levels of LDL cholesterol can increase the risk of atherosclerosis. Angkak is a fermented product from brown rice using mold Monascus purpureus. Angkak contains secondary lovastatin which functions as an anti-cholesterol. This study aims to determine the effect of the administration of brown rice Angkak to decreasing LDL levels at a dose of 15 mg/200gBB, 40 mg/200gBB, and 65 mg/200gBB in mice induced by high cholesterol feed. This type of research is true experimental laboratory withmethods pre and post test control group design. The results showed that Angkak dosages of 15 mg / 200gBB, 40 mg / 200gBB, and 65 mg / 200gBB were able to reduce levels in rats induced high cholesterol. The conclusion of this study is that red rice Angkak containing lovastatin has an anticolesterol effect on decreasing total cholesterol, LDL, and trigliseride levels in rats.
UJI FITOKIMIA DAN GC-MS BUAH API-API (Avicennia marina (FORSSK.) VIERH) Andrian Fernandes; Rahimahyuni Fatmi Noor’an
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.321

Abstract

Api-api (Avicennia marina (Forssk.) Vierh) is one of the species found in Barat Muara Kaeli Research and Education Forest. Traditionally, Api-api fruit stew water in China is used for the treatment of fever, sore throat and dysentery, while modern Api-api fruits have been used as food products. This study aims to determine the phytochemical component and predict the chemical content using GC-MS from Api-api fruit (Avicennia marina (Forssk.) Vierh) as a basic consideration use of derivative product. The Api-api fruit was obtained from the Api-api tree at the coordinates N 0°23'55.31" and E 117°25'33.55", then macerated using 96% ethanol. The concentrated 96% ethanol maceration results were then tested for phytochemicals and GC-MS. Api-api (Avicennia marina (Forssk.) Vierh) fruit phytochemical test results contained flavonoids, triterpenoids and steroids. Based on GC-MS test results on Api-api (Avicennia marina (Forssk.) Vierh) fruit contained γ-sitosterol (C29H55O) as much as 13.68%, dibutyl phthalate (C16H22O4) as much as 13.42%, Palmitic acid, ethyl esters (C18H36O2) of 7.85%, 9,12-Octadecadienoic acid, ethyl ester (C20H36O2) of 7.56% and Linolenic acid, ethyl ester (C20H34O2) of 6.33%, undecane (C11H24) of 7.25 %, 2-Propenamide, N-(1-cyclohexylethyl) at 6.78%, and several other minor compounds.
PERBANDINGAN EKSTRAKSI JAMUR TIRAM (Pleurotus ostreatus) DAN JAMUR KANCING (Agaricus bisporus) Christa Marthaningsih Prisida; Christe Mareta Ardika Sari; Tarasia Gandes Belani; Lusia Murtisiwi
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.326

Abstract

Mushrooms contain polysaccharides with the main components namely β-glucan and α-mannan. Polysaccharides can be useful as immune enhancers because beta-glucans can increase phagocytic activity and cytokine production. β- (1,3) -glukan has the ability to activate the cellular and humoral immunity system which is a component of the body's immune system. β- (1,3) -glukan increases the antimicrobial activity of mononuclear and neutrophil cells and increases the functional activity of macrophages. Polysaccharides from oyster mushrooms and button mushrooms can be extracted using the Yap & Ng method. The purpose of this study was to compare the yield of extracts produced from oyster mushrooms and button mushrooms. The method used in this research is water extraction method based on Yap & Ng. Data analysis of this study was carried out by calculating the percentage of extracts of oyster mushrooms and button mushrooms, then compared. The results of this study indicate that the yield of oyster mushroom extract is0,013% while the yield of button mushroom extract is 0,0055%. This shows the yield of oyster mushroom extract is greater than the yield of button mushroom extract if extracted by the Yap & Ng method.
KAJIAN ETNOFARMAKOLOGI TUMBUHAN OBAT OLEH MASYARAKAT DI KECAMATAN TANTA KABUPATEN TABALONG PROVINSI KALIMANTAN SELATAN Yani Mulyani; Ninda Ryana; Nita Selifiana
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.371

Abstract

Indonesia is a country with abundant biodiversity. Forests in Borneo are some of the most biodiverse forests in Indonesia although the efforts of the use of traditional medicines from plants have long been known by the community today. Inventory the type, part, way of use, dose, the purpose of how to obtain, the aspect of knowledge and utilization of medicinal plants used by the community in the village of Tanta Hulu and Warukin District, Tabalong District, South Kalimantan. Exploratory surveys and observational methods, through interviewing of semi-structures with 56 respondents using questionnaires including disease names, local names of plants, parts utilized, how to acquire, How to make them, assessment aspects of knowledge and utilization. the results of the study were 28 species of medicinal plants that belong to the 22 families used by the community, with The most numerous plant families are Asteraceae. The Plant parts used are leaves, roots, stems, bulbs, fruits, and flowers. The processing of plant parts include boiled, pounded, shredded and eaten directly. A total of 56 respondents assessed aspects of medicinal plants' knowledge and utilization
FORMULASI GRANUL ANTIDIARE DARI EKSTRAK ETANOL DAUN KRATOM ( Mitragyna spesioca Korth) dian kartikasari; suhaimi suhaimi
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.378

Abstract

Indonesian medicinal plants have been used both as traditional Indonesian medicine (herbal medicine), standardized herbal medicines or phytopharmaca. ethanol extract of kratom leaf (Mitragyna speciosa Korth) has been able to inhibit the growth of Escherichia coli bacteria and therefore researchers have developed a formula that is used as antidiarrheal, namely kratom leaf extract granule. The purpose of the concentration is avicel pH 101 that affects the physical properties of kratom leaf extract granules and on what formula meets the physical properties requirements of kratom leaf extract granules. The method used is the wet granulation method. With the ingredients used 5% kratom extract, evicel pH 101 and aerocil. By looking for the best aerosil pH 101 results and the best extract of kratom leaves, then the moisture content, flow time, angle of rest, and pH of the granule solution were evaluated. As for the results it can be concluded that the test carried out with 15% avicel concentration has a good effect on the physical granule Obtained the best formula is formula IV, it can be seen based on the test results fulfilling the granule requirements.
PEMANFAATAN LIMBAH DAUN BAWANG DAYAK (Eleutherine palmifolia L. Merr) SEBAGAI KRIM ANTI AGING DENGAN EMULGATOR ANIONIK DAN NONIONIK Eka Kumalasari; Erna Prihandiwati
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.386

Abstract

Dayak onions (Eleutherine palmifolia L. Merr) are typical plants of Borneo. Pharmacologically the part tubers are proven to have a therapeutic effect. Dayak onions grow in the tropics, one of which is in the Petuk Katimpun area of ​​Palangkaraya, Central Borneo, where there land are vast Dayak onion large farms. After harvesting Dayak onions will produce agricultural waste in the form of leaves that are not utilized and left to rot. Dayak onions leek waste extract contains flavonoid compounds and has antioxidant potential. Dayak onions antioxidants can be used to inhibit the aging of the skin and as an alternative to synthetic antioxidants which are harmful to health. Waste extract has a very strong antioxidant activity with an IC50 value of 45.33 ppm. On this basis, was made four cream formulas are made with different bases. Based on the physical test results all over formulas meet the good cream requirements. Formula III is a the formula with the damping antioxidant reduction the very biggest that is 63.84% ± 0.0891.
FORMULASI DAN UJI MUTU FISIK SEDIAAN LOTION EKSTRAK KULIT BUAH JAGUNG ( Zea mays L.) cikra ikhda Nur Hamidah safitri; Luluk Jubaidah
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.394

Abstract

Corn plant is a plant that is widely cultivated in Indonesia. Utilization of corn husk waste so far has only been used as animal feed. Chemical content contained in corn, among others, flavonoids, alkaloids, phenols, steroids, tannins, maysin. This study aims to produce a lotion of corn husk extract and test the physical quality of the lotion preparation. This research consisted of extraction using maceration method with 70% ethanol. Lotion formulation with extract concentrations of 10%, 20% and 30%. Evaluation of the physical quality of the preparations included organoleptic, homogeneity, pH, dispersibility and storage stability tests for 30 days. The results showed that Corn skin extract lotion has a pH of 6, thick form, fine texture, fragrant aroma, light brown color (10%), dark brown (20% and 30%).Texture is homogeneous. The spread of pH test in concentrations of 10%, 20% and 30%, ie 6.3 cm, 6.5 cm, 6.5 cm. The physical quality stability of the lotion stable at room (25°C-30°C) and cold temperature (2°C-8°C). The conclusion of this study is that there is no difference in the three lotions concentrations of 10%, 20% and 30% which are stored at room temperature and cold temperature. Keywords: Corn rind extract, physical quality, lotion
PENGUKURAN RENDEMEN DAN IDENTIFIKASI SENYAWA METABOLIT SEKUNDER PADA EKSTRAK DAUN TERAP (Artocarpus odoratissimus Blanco) DENGAN VARIASI PELARUT anna khumaira sari; Dwi Rizki Febrianti; muhammad fikri
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.400

Abstract

Terap plant have abundant health benefits. In the community of leaf terap empirically used as a lowering of high blood pressure by boiling a few leaves and then drinking boiled water. In this study the aim was to find out what percentage of yield obtained in leaf extracts applied with methanol, ethyl acetate and n-hexane solvents and any secondary metabolites contained in each extract. The type of research used in this study is non-experimental with a descriptive method which describes how much yield obtained in leaf extract using maceration method and using methanol, ethyl acetate and n-hexane solvents and then any secondary metabolites contained in the extract the leaves are applied with methanol, ethyl acetate and n-hexane solvents. The sample used is a plant from Banjang Village.. This study the management of the data used is qualitative. The results showed that the leaf extract with the methanol produced the largest yield of 13.57%, with secondary metabolite compounds flavonoids, tannins, quinones, saponins, and phenols, then with ethyl acetate solvents produced a yield of 5.52%, with content of secondary metabolites of flavonoids, tannins, phenols and quinones, while the smallest yields were n-hexane solvents, which is 2.30%, with triterpenoid and quinone secondary metabolites.
KOMPARASI BIAYA RIIL DENGAN TARIF INA-CBG’s PADA PASIEN RAWAT INAP KEMOTERAPI KANKER PARU DI RSUD ULIN BANJARMASIN noor aisyah; Yoga Saputra; Mardiana Mardiana
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.401

Abstract

Kanker paru merupakan penyakit yang memiliki tingkat morbiditas yang tinggi hampir diseluruh dunia. Kanker paru termasuk penyakit katastropik yang membutuhkan biaya tinggi dalam pengobatannya serta memiliki komplikasi yang dapat mengancam jiwa. Penelitian bertujuan untuk mengetahui perbedaan antara biaya riil dengan tarif INA-CBGs pada pasien rawat inap kemoterapi kanker paru peserta JKN di RSUD Ulin Banjarmain. Metode penelitian non eksperimental dengan rancangan cros sectional, diambil secara retrospektif dari berkas klaim JKN, penelitian merupakan penelitian yang bersifat komparatif. Teknik sampling yang digunakan adalah sampling jenuh jumlah, dengan jumlah sampel 49 pasien (108 episode perawatan). Instrument yang digunakan adalah lembar observasi, data diambil pada periode tahun 2018 dan dimasukkan dalam lembar observasi. Analisis data yang digunakan adalah uji one sample T-tes dan Mann-whitney Berdasarkan hasil penelitian dapat disimpulkan bahwa ada selisih positif antara total biaya riil dengan total tarif INA-CBGs pada tingkat keparahan I Rp.33.764.472, Tingkat keparahan II Rp.101.772.251 dan Tingkat keparahan III Rp.17.198.887. Berdasarkan uji SPSS menunjukan bahwa pada tingkat keparahan I dan II (kelas 1,2 dan kelas 1) tidak meiliki perbedaan secara signifikan karena nilai Æ¿ > 0,05, sedangkan tingkat keparahan I,II dan III (kelas 3) memiliki perbedaan secara signifikan karena nilai Æ¿ < 0,05.
TINGKAT PENGETAHUAN IBU TENTANG IMUNISASI DASAR PADA BAYI USIA 0-12 BULAN DI PUSKESMAS PEKAUMAN BANJARMASIN Noverda Ayuchecaria; novia Ariani
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.402

Abstract

The completeness of basic immunization needs to be considered by parents, especially mothers who generally bring their children to immunization in the puskesmas or posyandu. The level of knowledge of a mother is very influential on the success of complete immunization. Knowledge and awareness of the importance of immunization for children can increase the success of immunization programs. The purpose of this study was to determine the level of knowledge of a mother about basic immunization at the Pekauman Health Center. The type of research is Non-experimental research that is observational. The instrument used was a questionnaire sheet that had been tested for validity and reliability first. Pupolation used is the mother who brought her child and came during immunization to the Pekauman Health Center for the period of April and May 2019. The samples used with consecutive random sampling method, namely 110 mothers. Data analysis was done by making a percentage of each item statement and data then presented descriptively. The results of this study from 110 mothers showed that mothers had a good level of knowledge of 46.36% (51 mothers), sufficient level of knowledge of 55.82% (57 mothers) and a low level of knowledge of 1.82% (2 mothers).

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