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Muji Setiyo
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muji@unimma.ac.id
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+6282330623257
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ujas.urecol@gmail.com
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Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
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INDONESIA
Urecol Journal. Part D: Applied Sciences
ISSN : -     EISSN : 27972089     DOI : -
Core Subject : Science,
Urecol Journal. Part D: Applied Science is a peer-reviewed journal published by Konsorsium LPPM Perguruan Tinggi Muhammadiyah Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY. This scientific journal specifically discusses the findings, new methods, and research experiences in applied sciences from the University Research Colloquium (URECOL) which is held twice a year.
Articles 41 Documents
Hepatotoxicity Risk Profile of Indonesian Due to Polymorphism of NAT2 and CYP2E1 in Isoniazid Metabolism Setiyo Budi Santoso; Puji Umi Chabibah; Prasojo Pribadi
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (360.387 KB) | DOI: 10.53017/ujas.11

Abstract

This article presents data on drug-induced liver injury events' risk profile due to NAT2 and CYP2E1 polymorphisms in isoniazid metabolism in Indonesian populations among various populations of several countries. The research took place through a review of the literature obtained from google scholar. The library search uses three variants of the keyword: (1) "pharmacogenomic and tuberculosis and INH and NAT2 and CYP2E1 and polymorphism", (2) "isoniazid and hepatotoxicity and polymorphism and N-acetyltransferase," (3) "isoniazid and hepatotoxicity and polymorphism and CYP2E1". Analysis of hepatotoxic risk based on the odds ratio (confidence interval) using Stata MP 14th edition software. The study of drug-induced liver injury events' risk based on various NAT2 acetylation rates involved 2,140 populations from 8 countries, while the risk analysis based on CYP2E1 allele variety involved 1,530 populations from 5 countries. The literature review shows that the Indonesian population's isoniazid-induced liver injury events' risk with slow acetylator NAT2 enzymes and people with CYP2E1*c1/c2 is three times higher than other populations in various countries. Further, people who have the combination slow acetylator NAT2 and CYP2E1*c1/c2 have more drug-induced liver injury events' risk.
Tannin Analysis of Red Roselle Petals (Hibiscus Sabdariffa, L.) using Permanganometry Method Anita Agustina Styawan; Aristhasari Putri; Refida Ramadhani Nur Cholifa
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.316 KB) | DOI: 10.53017/ujas.31

Abstract

Red roselle (Hibiscus sabdariffa L.) is a plant that can be used by the community as traditional medicine. Rosella flower petals contains protein, fat, minerals, alkaloids, flavonoids, and tannins. Red rosella is effective in preventing vertigo, antihypertension, antidiabetic, anticancer, and antioxidants. Tannins are known as one of the active ingredients contained in the petals of red rosella flowers. Tannins are polyphenolic protein. This study aims to determine the levels of tannin in the extract of red rosella flower petals using permanganometry titration. The research method used was observational. This study used a sample of red roselle flower petals. The sample was tested qualitatively using FeCl3 1%. Analyzed quantitatively using permanganometry titration. The results showed that qualitatively the positive sample contained tannins which was marked by a change in color to dark blue dark. Quantitatively the sample was titrated with KMnO4, the tannin content in red roselle flower petals was 13,73 % b/b.
Gel Formulation for Hand Sanitizer from Ethanol Extract of Mulberry Leaf (Morus Alba L.) Sutaryono Sutaryono; Hendra Budiman; Anita Agustina Styawan; Nurul Hidayati; Dayah Ainus
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (160.556 KB) | DOI: 10.53017/ujas.37

Abstract

During the Covid 19 pandemic, a handsanitizer product has emerged which functions as a hand washing disinfectant for the prevention of the Covid 19 virus. One of the ingredients that can be made handsanitizer gel is the mulberry plant (Morus alba L.) because it contains many flavonoids which act as antiseptics against bacteria. The research objective was to determine the handsanitizer gel formulation with the concentration of carbopol and propylenglycol which can produce good physical properties. The research design used an experiment, with the mulberry leaf preparation material macerated using 70% ethanol. Mulberry leaf ethanol extract (Morus alba L.) as the active substance and made 3 formulas with variations in the concentration of carbopol: propylenglycol formula I (0.5%: 15%), formula II (1.25%: 12.5%), formula III (2%: 10%). The three formulas were tested for physical properties and analyzed by ANOVA with a confidence level of 95%. The results showed that the handsanitizer gel formulation with carbopol increased viscosity and stickiness, while propylenglycol increased the dispersibility. The 1.25% formula: 12.5% ??produces the best physical properties, with a pH test of 6, a viscosity test of 150 dPas, a spreadability test of 6.5 cm, a sticky power test of 2.39 seconds and a protective power test without red stains.
Effect of Diabetes Exercise on Depression Score in Type II Diabetes Mellitus Patients Romadhani Tri Purnomo; Puput Risti Kusumaningrum; Fitriana Noor Khayati; H Harjana
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.29 KB) | DOI: 10.53017/ujas.38

Abstract

Diabetes mellitus is a chronic disease that occurs when the pancreas is unable to produce enough insulin. Indonesia is the 7th most DM sufferer in the world. Patients when diagnosed with DM experience psychological stress, anxiety because they are no longer like normal people, causing depression. The way to reduce depression is to do physical activity such as gymnastics. The purpose of this study was to determine the effect of diabetic exercise on the reduction of depression scores at Persadia RSI Klaten. This study used a quasy experimental pre post test design with a cross sectional approach. The study population was type II DM patients who joined Persadia Islamic Hospital Klaten. The sampling technique was purposive sampling with a total of 30 respondents. The data collection instrument used the PHQ questionnaire. Bivariate data analysis using the Wilcoxon test. The results of the research on the characteristics of respondents were dominated by women as many as 23 (76.7%). The average age of the respondents was 49 years. The ethnic group is dominated by Javanese as many as 28 (93.3%). Most of the respondents' occupation is Labor 12 (40.0%). The average score for depression before the intervention for diabetic exercise was 7,400 and after the intervention for diabetic exercise decreased to 2.166. The results of the Wilcoxon test showed that there was a significant effect of diabetes exercise on the reduction of depression scores in type II diabetes mellitus patients at Persadia RSI Klaten values ??(p = 0.000, Z = -4.813). Conclusion based on the results of the study, the average depression score in Type II DM patients before diabetes exercise was 7,400. Meanwhile, the average depression score after diabetes exercise was 2.166. The results of statistical tests showed that there was an effect of diabetes exercise on depression scores in Type II DM patients with a p value of 0.000.
Investigative Study on Self-Concept of Diabetes Mellitus Ulcer Patients Istianna Nurhidayati; Marwanti Marwanti; Susminingsih Susminingsih; Sutaryono Sutaryono
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.668 KB) | DOI: 10.53017/ujas.52

Abstract

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormal insulin secretion. Uncontrolled hyperglycemia condition can cause complications in the foot neuropathy and ulcers are often associated with diabetes. Diabetic ulcers have an impact on loss of bodily function, decreased activity tolerance resulting in disruption to the individual's self-concept. The aim of this study was to analized relationship between diabetic ulcers and self-concept of diabetes mellitus patients in RSUP dr. Soeradji Tirtonegoro Klaten. The study design used case control with non-probability, sampling technique was consesecutived sampling. The number of samples used were 82 samples divided into two groups: 41 controls 41 cases. analysis of the results using bivariate test with Chi-Squere. Comparative test results with Chi-Squere between DM ulcers with self-concept in the control group and case group were adjusted p value = 0.034 (OR = 0.35). Conclusion there was a relationship between diabetic ulcers with the self-concept of diabetes mellitus patients at RSUP dr. Soeradji Tirtonegoro Klaten. Based on these findings, the proposed interventions that could be implemented was to increase self concept patient with diabetic ulcer.
Design and Implementation of Sterilization Chamber with Ozone and UV-C Light to Break the Transmission of Covid-19 Muhammad Latifur Rochman; Lilik Budiyarto; Muhammad Iqbal Al-Fikri; Khoirul Fa’i; Prasasti Bayu Aji Pramono; Riyan Tri Aditya Pamungkas; Baginda Pangidoan Tanjung; Refaldy Pristiwantoro; Widha Bagus Fahriansyah; Agung Setyo Pambudi; Ahmad Irfan; Riyan Adhy Pratama; Lalank Samudra Mukti Hidayat; Setyo Widiantoro; Darmawan Rois; Muhammad Mauludin Kharim; Wahyu Danu Romadlon; Dwi Restianto; Muji Setiyo; Budi Waluyo; Bagiyo Condro Purnomo; Suroto Munahar; Noto Widodo; Saifudin Saifudin
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (464.204 KB) | DOI: 10.53017/ujas.55

Abstract

The emergence of Corona Virus Disease 19 (Covid-19) required a new method to control its spread. During this time, controlling COVID-19 was carried out by implementation of a sterilization chamber using a liquid-based disinfectant. However, the use of liquid-based disinfectants has been evaluated to be less effective because it allows disrupting the respiratory tract. Therefore, this work presents a negative pressure sterilization chamber using Ozone and UV-C lamp. Ozone has been recommended by the Indonesian Institute of Sciences (LIPI) as a substitute for liquid-based disinfectants. In addition, to maximize performance, the chambers are added with UV-C lamps. The negative pressure sterilization chamber with Ozone and ultraviolet lamps was successfully created with the main parts of the cubicle chamber, an Ozone generator, at least one ultraviolet lamp, exhaust fan, switch, and a timer. The negative pressure sterilization chamber with Ozone and ultraviolet lamps according to this work, where the Ozone supply from the Ozone generator is made automatically to the door opening and closing. The duration of the Ozone supply was regulated by a timer. Then, the ultraviolet lamp can be activated together with Ozone or independently. With the implementation of this sterilization chamber, the spread of the Covid-19 virus is expected to be suppressed in a safer way than using liquid-based disinfectants.
Baking Soda and Peroxide Formulation as Dental Whitening Gel Herma Fanani Agusta; Alfian Syarifuddin; Fitriana Yuliastuti; Misya Putri Kurnia Pradani
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.019 KB) | DOI: 10.53017/ujas.56

Abstract

Indonesian society began to make appearance as a primary need. Appearance becomes important for middle and upper social classes which reaches 60-70% in Indonesia. Researchers are trying to find a combination formula of two teeth whitening ingredients (Baking Soda and Peroxide). The study uses an experimental method, which is to make a dental gel with variety of gradient constituent formulas, including F1, F2, F3, F4, and F5. F5 is the most optimal formula with best stability test results among other. F5 with Peroxide concentration of 30% had teeth whitening activity of 38% by two months in vitro test on adult teeth samples.
Characteristics of Communities Affected by Covid-19 on Archaeological Sites and Cultural Heritage Sites in Kalijambe, Sragen, Central Java in 2020 Kuswaji Dwi Priyono; Ongky Fernanda
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 2 (2021): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.67 KB) | DOI: 10.53017/ujas.79

Abstract

This study aims to determine the characteristics of the community affected by the Covid-19 Pandemic Outbreak on Archaeological Sites and Cultural Heritage Sites in KalijambE District, Sragen Regency, Central Java. The survey method was used in this study, with structured interviews with 78 respondents and 14 businessmen and traders in the tourism object. Determination of respondents using the Convenience Sampling method provided that the business owner is 1,000 m away from the museum with a circular pattern. The results of this study found that the socio-economic characteristics of the people affected by the Covid-19 pandemic experienced a decline in people's income with an average income of 3 million. The education level of the community around the museum is the highest in SMA and SMP. The number of family dependents is 1-3 people and the number of dependents of school age children is 1-2 people in one family head. The domination of the age group of the community around the museum is 25 - 45 years, the community is classified as productive. Factors that influence the development of the museum, namely, the economic factor of the community feels an increase in income with the existence of the museum. The social factor of the opening of wide employment opportunities makes the unemployment rate decrease so that the people around the museum live an easy life, fulfill their needs and reduce the level of employment.
Study of Application Liquid Organic Fertilizer and Monosodium Glutamate on Chlorophyll and Yield of Cannabis Agus Suprapto; Esna Dilli Novianto; Mahdalina Mursilati
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 2 (2021): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.756 KB) | DOI: 10.53017/ujas.80

Abstract

Cannabis (Canna edulis Kerr.) is a plant source of local food that contains carbohydrates so that cannabis is included as an alternative food crop to replace rice. The purpose of this study was to obtain a dose of liquid organic fertilizer (POC) and monosodium glutamate (MSG) on the chlorophyll content and yield of cannabis. The research was conducted from October 2020 to April 2021 on agricultural land in Plumbon Village, Selopampang, Temanggung with an altitude of 460 m above sea level. The research method was arranged in a completely randomized block design using a factorial experiment consisting of two factors and repeated three times. The first factor is the POC dose with levels: 0 mL/L, 2 mL/L, 3 mL/L, and 4 mL/L. The second factor was the dose of MSG consisting of: 0 g/plant, 3 g/plant, 6 g/plant, and 9 g/plant. Data were analyzed using analysis of variance with 1% and 5%. Data that showed significant differences were tested for orthogonal polynomial. The results showed that the addition of 2-3 mL/L of POC gave very significant differences in the amount of leaf chlorophyll and the fresh weight of tubers. The addition of MSG gave significantly different results to the fresh weight of tubers. The dose interaction of POC and MSG was significantly different to the fresh weight of tubers and significantly different to the amount of leaf chlorophyll.
The Relationship between the Level of Compliance in the Physiotherapy Program and the Functional Ability of Patients with Genu Osteoathritis at Dr. Moewardi Hospital Farid Rahman; Hafiz Arief Nur’ana; Dinik Ayundya Marlis; Ilham Setya Budi; Dinda Ayudya Puspitaningrum
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 2 (2021): August-Dec
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.798 KB) | DOI: 10.53017/ujas.84

Abstract

Genu Osteoathritis is a degenerative disease characterized by damage to articular cartilage so that it can cause symptoms of stiffness and pain in the knee joint that will affect the functional ability of adherence or also called compliance is an important component in the physiotherapy program, especially exercise therapy for patients, because adherence greatly determines the success rate of the outcomes compiled by the physiotherapist. The purpose of this study was to determine the relationship between the level of patient compliance in the physiotherapy program with the functional abilities of patients with genu osteoathritis. This research method used a correlational research method with cross sectional approach. Namely the research method used to find the relationship between the independent variable and the dependent variable. The population in this study was 30 people. The measurement of functional ability using a questionnaire is the Knee Injury and Osteoathritis Outcome Score (KOOS) and to measure the respondent's level of compliance using the Exercise Adherence Rating Scale (EARS). The results of the study were analyzed using the product moment correlation test and the p-value was 0.347. So it can be concluded that there is no corelation between the level of adherence with the functional abilities of patients with genu osteoathritis in RSUD Dr. Moewardi.