Jurnal Kedokteran Diponegoro
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
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<![CDATA[BRONKHOPNEUMONIA AS COMORBIDITIES OF CMV INFECTION : STUDY CASE ON 1 YEAR 9 MONTHS OLD BOY ]]>
<![CDATA[Wulan Widiasmaran]]>;
<![CDATA[Ayu Anggraini Kusumaningrum]]>;
<![CDATA[Fitri Amalia]]>;
<![CDATA[Dimas Tri Anantyo]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.28187
<![CDATA[Background. Pneumonia is an acute lung parenchyma inflammation, which includes the alveoli and tissues. According to RISKESDAS 2018, pneumonia prevalence of children under five years old in Indonesia has increased from 1.6% in 2013 to 2% in 2018. Cytomegalovirus infection (CMV) is the most common congenital infection and causes high morbidity in newborns. The purpose of this case is to report a case in Semarang and conduct a discussion of pneumonia cases and a history of CMV infection so that proper treatment can immediately start.Method. Anamnesis carried out on February 1, 2020, at Government Hospital in Semarang. Data obtained from allonamnesis with the patient's mother, physical examination, supporting examinations, and medical records of patients. Case. Patient of a boy aged one year nine months that come to the ER with a chief complaint of fever and cough.Discussion. A boy aged one year nine months with fever and cough complaints about five days before entering the hospital. Sputum culture examination revealed the presence of Klebsiella pneumonia, then treated with cefoperazone sulbactam. The patient had a history of cytomegalovirus infection but not optimally treated because of the high avidity value.Conclusion. Patient has diagnosed with bronchopneumonia et causa Klebsiella pneumonia.]]>
<![CDATA[BARRIERS TO THE IMPLEMENTATION OF ISONIAZID PREVENTIVE THERAPY AMONG CHILDREN UNDER FIVE YEARS OLD IN CLOSE CONTACT WITH SPUTUM SMEAR-POSITIVE TB PATIENTS ]]>
<![CDATA[Tirsa Hizkia Saverina Nugroho]]>;
<![CDATA[Anindita Soetadji]]>;
<![CDATA[Dea Amarilisa Adespin]]>;
<![CDATA[Stefani Candra Firmanti]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29456
<![CDATA[Background: The implementation of isoniazid preventive therapy (IPT) among children under five years old in close contact with sputum smear-positive TB patients is still low. Only 21,7% of children implemented the IPT in Central Java in 2017. Assessment of the barriers to IPT implementation needs to be carried out in the control of child TB cases.Objective: To analyze the barriers to IPT implementation among children under five years old in close contact with sputum smear-positive TB patients.Methods: A cross-sectional study was conducted among children (age <5 years) in close contact with sputum smear-positive TB patients. Data were collected from KRMT Wongsonegoro Hospital, Dr. Adhyatma, MPH Hospital, Puskesmas Kedungmundu, and Puskesmas Bandarharjo. Structured questionnaires were used to obtain sociodemographic information and to identify associated barriers to IPT implementation. The data were analyzed using Fisher’s exact test.Results: The majority (93,3%) of the total subject (75) of this study did not implement the IPT. The results of the bivariate analysis showed that distance to health facilities (p=0.024), perceived barriers (p=0.016), and cues to action (p=0.001) had a significant association as barriers to IPT implementation. Meanwhile age (p=0.622), gender (p=2.121), education level (p=0.073), economic level (p=0.521), knowledge level (p=0.166), and perceived threats (p=0.316) had no significant association as barriers to IPT implementation.Conclusion: IPT implementation rate is low. The barriers were distance to health facilities, perceived barriers, and cues to action.]]>
<![CDATA[CORRELATION BEHAVIOR OF MANTAINING ORAL AND DENTAL HEALTH AND ENVIRONMENTAL FACTORS WITH DENTAL CARIES IN 11-12 YEARS OLD CHILDREN IN SD NEGERI 1 AND MI NEGERI KALIKURMO BRINGIN SUBDISTRICT ]]>
<![CDATA[Dandy Iqbal Saputra]]>;
<![CDATA[Arwinda Nugraheni]]>;
<![CDATA[Aras Utami]]>;
<![CDATA[Avina Anin Nasia]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.30009
<![CDATA[ABSTRACT Background: Oral and dental health problems in Indonesia still occur a lot. Poor oral and dental health will impact the individual by causing pain, reducing quality of life and decrease individual productivity. Caries is serious oral and dental health problem in society, therefore it needs attention and involvement from all parties to overcome it. Environmental factors are very important in maintaining oral and dental health and teaching healthy living behaviors.Objective: To determine the correlation behavior of maintaining oral and dental health and environmental factors with caries incidence in 11-12 years old children in Bringin Subdistrict. Methods: This study was an analytic observational study with cross sectional study approach. This research sample method using total sampling method. The sample used is all members of the population as many as 60 research subjects. This study consist of 4 assessment factors, there are the consumption level of cariogenic foods, tooth brushing habits, parents income level, and parents education. The results of this study are the scores of these four factors and the DMF-t index. Before participating In this research, subjects were asked to fill out a questionnaire and informed consent. Examination performed by using a sonde and mirror mouth. Results: There was a correlation on the results of chi square test on the level of education and cariogenic food consumption with caries status in 11-12 years old children in Bringin Subdistrict. P = 0.001 (P<0.05).Conclusion: There is a correlation on behavior of maintaining oral and dental health and environmental factors with dental caries in 11-12 years old children in SD 1 and MI N Kalikurmo, Bringin Subdistrict.]]>
<![CDATA[CHARACTERISTICS OF ATOPIC DERMATITIS IN PUSKESMAS (PUBLIC HEALTH CENTER) MASARAN 1 SRAGEN REGENCY ]]>
<![CDATA[Muhammad Ilham Arifin Munthaha]]>;
<![CDATA[Retno Indar Widayati]]>;
<![CDATA[Liza Afriliana]]>;
<![CDATA[Aryu Candra]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29557
<![CDATA[Background: Atopic dermatitis is a chronic and residive inflammatory skin disease with mild to severe itching and occurs mostly in infant and children. The cause not certainty known and multifactorial.Objective: This study aims to Know the Characteristics of Atopic Dermatitis in Puskesmas Masaran 1, Sragen Regency.Method: This study is descriptive with a retrospective cross-sectional design. Secondary data retrieved from medical records atopic dermatitis patients at Puskesmas Masaran 1 in the period 1 January-31 December 2019 with a sample 248 people then analyze using a computer program.Result: The most atopic dermatitis sufferers were the adult age group (151 people), female gender (139 people), not working (96 people), atopic history disease found in 112 patients, site of the most lesions was lower extremities (71 patients), and the choice therapy is polytherapy with three types of drugs in 103 patients. Types of drugs are corticosteroids (224 patients), antihistamines (212 patients), and vitamins/minerals (200 patients).Conclusion: Characteristics of atopic dermatitis in Puskesmas Masaran 1 are the most age group is adults, gender is female, types of work is not working, atopic history is atopic dermatitis, and therapeutic options are corticosteroids, antihistamines, and vitamins/minerals.]]>
<![CDATA[THE ASSOCIATION OF DIABETES DURATION WITH THE SEVERITY OF DIABETIC RETINOPATHY ]]>
<![CDATA[Intan Lamy Manao]]>;
<![CDATA[Hesti Triwahyu Hutami]]>;
<![CDATA[Fifin Luthfia Rahmi]]>;
<![CDATA[Arnila Novitasari Saubig]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29942
<![CDATA[Background: The prevalence of diabetic patients is increasing over the years. It will increase the incidence of microvascular complications due to prolonged hyperglycemia in diabetic patient. Diabetic retinopathy is one of microvascular complication which is one of the leading causes of blindness in the world. Prolonged hyperglycemia in diabetic patient cause toxicity to the retina which cause nerve and vascular damage and death to the retina. In this study was analyzed the association of diabetes duration with the severity of diabetic retinopathy associated with many cases of delay in diagnosing diabetes recentlyObjective: This study aims to investigate the association of diabetes duration with the severity of diabetic retinopathyMethods: A cross-sectional design was performed by collecting data from the medical records of diabetic patients who were diagnosed with diabetic retinopathy in Diponegoro National Hospital in July-December 2019 using purposive sampling method. Research subjects were 51 patients who fulfilled the inclusion and exclusion criteria. The data were analyzed using non-parametric Chi Square test with p < 0.05 was considered statistically significant.Results: Prevalence was more in the age group of 51-60 years (45,1%), female (58,8%), diabetics <5 years (41,2%), and PDR (72,6%). Chi Square analysis shows no statistically significant association between duration of diabetes with the severity of diabetic retinopathy (p = 0,881)Conclusion: There was no statistically significant association between duration of diabetes with the severity of diabetic retinopathy]]>
<![CDATA[IN VITRO ANTIMICROBIAL ACTIVITY OF COCONUT SHELL LIQUID SMOKE AGAINST Candida albicans AND Lactobacillus acidophilus ATTRIBUTING TO ENDODONTIC TREATMENT FAILURE ]]>
<![CDATA[Isniya Nosartika]]>;
<![CDATA[Nadia Hardini]]>;
<![CDATA[Tyas Prihatiningsih]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29958
<![CDATA[L. acidophilus bacteria and C. albicans fungi are the most common microorganisms isolated from the oral cavity of patients suffering from post-treatment of root canal endodontic infections. Chlorophenol Camphor menthol (ChM) is one of the antimicrobials used for root canal sterilizer but it still has many flaws. Coconut shell liquid smoke (CS-LS) is a natural product that has an antimicrobial activity and non-toxic chemical compounds for humans. This study aims at determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of L. acidophilus bacteria and C. Albicans fungi and comparing the antimicrobial activity between CS-LC with commercial root canal sterilization. The MIC and MBC of CS-LS were measured using 10 different concentrations ranging from 10-100%. MIC was determined by the broth dilution method. All concentration was cultured on each agar media to determine its MBC. The data were analyzed using the comparative test of Kruskall-Wallis with post-hoc Mann-Whitney. MIC and MBC of C. albicans were 10% of CSLS. Meanwhile, L. acidophilus has the MIC with a 50% concentration of CSLS and MBC with a 60% concentration of CS-LS. No significant difference in CS-LS and ChKM was found. Thus, CS-LS has a potential for endodontic treatment failure. Further research should be conducted to know other potential uses of CS-LS in dentistry.]]>
<![CDATA[THE EFFECT OF HIGH INTENSITY INTERVAL TRAINING (HIIT) ON SHORT-TERM MEMORY AMONG MEDICAL STUDENT OF DIPONEGORO UNIVERSITY ]]>
<![CDATA[Nadia Ayu Octaviani]]>;
<![CDATA[Sumardi Widodo]]>;
<![CDATA[Arinta Puspita Wati]]>;
<![CDATA[Tanjung Ayu Sumekar]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29279
<![CDATA[Background: High Intensity Interval Training (HIIT) is an aerobic exercise consisting of high intensity of physical exercise interspersed with low intensity of physical exercise. HIIT has been known that can improve cognitive function. Medical students has low physical activity that can affect on cognitive function including short-term memory. Short-term memory is important in learning process which can affect on academic performance. Objective: To determine the effect of High Intensity Interval Training (HIIT) on an individual’s short-term memory. Methods: This study used quasi experimental pretest and posttest design. The research subjects were 29 female students of the Faculty of Medicine, Diponegoro University with the average age of 19-22 years with normal BMI, divided in 2 groups. Experimental group (n=14) was instructed to do 6 weeks of HIIT (3 times a week) and control group (n=15) was instructed to not to do any exercises. Short-term memory was measured with Scenery Picture Memory Test (SPMT). The significance of the data was analyzed with paired sample t-test and independent sample t-test. Results : A significant increase (p<0.001) in memory score before and after HIIT, from 18.07±1.49 to 20.21±1.37. The posttest memory score of HIIT group (20.21±1.37) was significantly (p=0.034) higher than the control group (18.67±2.23). Meanwhile, the memory score at the pretest between the 2 groups was no significant differences (p=0.621). Conclusion: HIIT can improves short-term memory.Keywords: High Intensity Interval Training (HIIT), Short-term Memory, Scenery Picture Memory Test (SPMT).]]>
<![CDATA[ANTIHYPERURICEMIC EFFECT OF RED GINGER POWDER AND LIME JUICE COMBINATION IN WISTAR RATS INDUCED HYPERURICEMIA ]]>
<![CDATA[Eva Susanty Purba]]>;
<![CDATA[Chikita Dian Rahma Saphira]]>;
<![CDATA[Salma Yasmine Azzahara]]>;
<![CDATA[Edwin Basyar]]>;
<![CDATA[Muflihatul Muniroh]]>;
<![CDATA[Ainun Rahmasari Gumay]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29374
<![CDATA[Background: Hyperuricemia is an abnormally high level of uric acid in the blood. Ginger and lime are natural ingredients that contain antioxidants and anti-inflammatory which could reduce blood uric acid levels. This study aims to prove the effect of red ginger powder and lime juice combination on uric acid levels of Wistar rats induced hyperuricemia.Methods: Experimental research with pre and post-test only control group design. Thirty Wistar male rats, aged 2-3 months, weighed 150-350 grams randomly divided into 5 groups. Group C1 was normal control group. Group C2 was induced by single intraperitoneal injection of potassium oxonate (300mg/kgBW). Group T1, T2, T3 were induced by potassium oxonate and orally administered by combination of red ginger powder (300, 600, 1200 mg/200gBW) and lime juice (2ml/150gBW). Blood samples in each group will be collected in 1 hour after treatment. Uric acid levels were measured using the TBHBA uric acid method.Results: Uric acid level in T1, T2, and T3 group was significantly lower than C2 group (p<0,05). The most effective dose to reduce uric acid levels was 1200mg/200gBW red ginger in combination with 2ml/150gBW lime juice (T3 group).Conclusion: Red ginger powder and lime juice may reduce the blood uric acid levels in Wistar rats induced hyperuricemia.]]>
<![CDATA[MEDICAL PROBLEM, CONCEQUENCES TO ORAL CARE IN GERIATRIC PATIENT ]]>
<![CDATA[Nadia Hardini]]>;
<![CDATA[Oedijani Santoso]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29985
<![CDATA[Introduction: Oral and maxillofacial tissue status has a significant impact on the systemic health of elderly patients. Elderly patients without oral diseases are rare to find by dentists. Literature Review: Prevention and treatment for caries and periodontal diseases should be done for elderly patients, except in particular conditions when its not worth the risks treatments. Although the relationship between oral diseases and systemic diseases is still controversial and unresolved, it can be assumed that elderly patients have a greater risk of acute and chronic oral infections due to the use of various drugs and medical disorders, impaired immune function, age related impaired kidney, liver and cardiovascular dysfunction. Conclusion: While on duty, dentists who provides care to elderly patients, must know the medical history and systemic review, and understands general medical problems that affects oral care of the elderly.Keyword : medical problem, elderly, oral treatment]]>
<![CDATA[THE EFFECT OF STRATIFIED DOSES OF CURRY LEAF EXTRACT (MURRAYA KOENIGII) ON TOTAL CHOLESTEROL AND TRIGLYCERIDES IN MALE SPRAGUE-DAWLEY RATS INDUCED BY HIGH FAT FEED ]]>
<![CDATA[Muhammad Iqbal Reynaldi]]>;
<![CDATA[Santoso Santoso]]>;
<![CDATA[Kusmiyati Tjahjono]]>
<![CDATA[ JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) ]]>
Publisher : <![CDATA[Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia ]]>
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DOI: 10.14710/dmj.v10i1.29256
<![CDATA[Background: High level of total cholesterol and tryglicerides in the blood can cause atherosclerosis. Curry leaves are often used by the society to reduce total cholesterol and trygliceride levels in the blood, but no studies have examinded the effective dosage of curry leaf extract to reduce total cholesterol and triglyceride levels.Aim: This study aims to determine the effect of giving curry leaf extract (Murraya koenigii) on cholesterol and triglyceride levels of male Sprague-Dawley rats induced by high fat feed.Methods: This study was a true experimental study with a pre-post test with randomized control group design. The subjects of the study were male Sprague-Dawley rats induced by high fat feed for 10 days. Cholesterol and triglyceride levels were measured by enymatic methods. Then, the data were analyzed using paired t test and for P3 group total cholesterol using the Wilcoxon test to analyze the differences in total cholesterol and triglyceride levels between before and after given the curry leaf extract, Repeated Anova test to analyzed the differences between groups which was then followed by post hoc bonferoni and One Way Anova to analyze the differences in total cholesterol and triglyceride levels between groups.Results: There was no significant differences in total cholesterol levels between before and after given the curry leaf extract at a dose of 200 mg/KgBW, 300 mg/KgBW, and 400 mg/KgBW (p= 0.641 for the P1 group, p= 0.385 for the P2 group and p= 0.398 for the P3 group). In contrast to triglyceride levels, there were differences in triglyceride levels before and after administration of curry leaf extrcat at a a dose of 300 mg/KgBW (p= 0.012), while the other groups were not significant.Conclusion: The stratified doses of curry leaf extract (Murraya koenigii) in this study could not reduce cholesterol level and triglyceride levelKeywords: Curry leaf extract; Dyslipidemia; Total Cholesterol; Triglyceride ]]>
