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All Journal Jurnal NERS Jurnal Teknologi Laboratorium Molecular and Cellular Biomedical Sciences (MCBS) Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Dharma Bakti Medica Hospitalia Journal of Pharmaceutical Care Anwar Medika Jurnal Pengabdian Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan Indian Journal of Forensic Medicine & Toxicology Jurnal Olahraga Pendidikan Indonesia (JOPI)
Nurdianto, Arif Rahman
STIKES Rumah Sakit Anwar Medika
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Perspective of molecular immune response of SARS-COV-2 infection Rohmah, Martina Kurnia; Rahman Nurdianto, Arif
Jurnal Teknologi Laboratorium Vol 9 No 1 (2020): 2020 (1): Special Edition "COVID-19"
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (620.136 KB) | DOI: 10.29238/teknolabjournal.v9i1.218

Abstract

COVID-19 is a type of Pneumonia caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). When COVID-19 arise in Wuhan China and rapidly spread throughout to the World, we need to learn how pathogenesis and immune responses occur in the bodies in more detail. COVID-19 is the third Severe Respiratory Disease outbreak caused by the Coronavirus in the past two decades after Severe Acute Respiratory Syndrome (SARS) in the 2002 and Middle East Respiratory Syndrome (MERS) in 2012. The Articles from PUBMED and Research Gate were searched for studies on the immune response of COVID-19 infection by SARS-CoV-2. SARS-CoV-2 increases the number of neutrophils, suppresses IFN, increases the activity of Th1/Th17, B cells, CD8+ and CD4+, and causes cytokine storms especially pro-inflammatory cytokines which can increase respiration disorders and multi-organ damage. This review tries to explain about pathogenesis and immune responses of COVID-19 to provide a reference in designing the appropriate immune intervention for treatment and therapeutic such as drug or vaccine based on the recent research progress SARS-CoV-2 and previous studies about SARS CoV and MERS CoV.
Edukasi Pola Makan Sehat kepada Pasien Peserta Prolanis Di Puskesmas Trosobo Sidoarjo Nisyak, Khoirun; Amanda, Eviomitta Rizki; Hisbiyah, A’yunil; Prasetya, Yulianto Ade; Nurdianto, Arif Rahman
DHARMA BAKTI Dharma Bakti- Vol 4 No 2 - Oktober 2021
Publisher : LPPM IST AKPRIND Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Participants of the Chronic Disease Management Program (PROLANIS) at the Trosobo Health Center are a group of patients with diabetes mellitus and hypertension whose condition needs to be monitored regularly. Diet is one of the important factors that affect the stability of the health condition of patients in the Prolanis group. The purpose of this program is to provide education on healthy eating patterns for Prolanis participants. The method of activities carried out is counseling and workshops with a total of 30 patients. Counseling activities and workshops are carried out by involving families who care for patients. Evaluation of the success of the program is determined by the patient's level of understanding about healthy eating patterns and fasting blood sugar levels and the patient's blood pressure to normal and stable levels over time. Based on the results of the program evaluation that has been carried out, 90% of Prolanis patients understand about healthy eating patterns and apply them in their daily lives.
KOMPLIKASI EMBOLI PARU PADA CORONA VIRUS DISEASE 2019 (COVID – 19) : Sebuah Tinjauan Literatur Nurdianto, Arif Rahman
Journal of Pharmaceutical Care Anwar Medika (J-PhAM) Vol 4 No 1 (2021): Journal of Pharmaceutical Care Anwar Medika
Publisher : STIKES Rumah Sakit Anwar Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36932/jpcam.v4i1.72

Abstract

Background: The respiratory disease that attacks respiratory system makes a high mortality rate which one of the complications of its manifestation is thrombotic in the amount of 31% , where from all these complications, 87% of which are pulmonal embolic. It is an emergency state that can cause death and as it needs fast, accurate diagnostic and handling for better outcome for the patients.MethodThis Study compares many sources form research articles, case reports, and international journal reviews.Result: Scoring, D dimer, and the other imaging examination that available at health center can be used together for Covid 19 screening to find out pulmonal embolism as a Covid 19 complication.Conclusion: the accurate dan precise pulmonal embolism in Covid 19 used scoring and imaging that available in the health center makes the prompt treatment dan makes a better outcome.
Penanganan Pasien COVID-19 dengan Schizofrenia di Wilayah Kerja Puskesmas Trosobo (Laporan Kasus) Nurdianto, Arif Rahman
Journal of Pharmaceutical Care Anwar Medika (J-PhAM) Vol 4 No 1 (2021): Journal of Pharmaceutical Care Anwar Medika
Publisher : STIKES Rumah Sakit Anwar Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36932/jpcam.v4i1.80

Abstract

Background: Schizophrenia patients infected with COVID-19 have become a problem in handling COVID-19 at the Sidoarjo regency community health center. Selection of drugs and handling of patients with their environment requires a different approach from normal patients. Research on COVID-19 with schizophrenia patients is very limited. The COVID-19 pandemic makes patient services and access unlike before the pandemic and is very limited so that access to schizophrenia patients, both controlled and uncontrolled, is still lacking and the effectiveness of therapy in schizophrenia patients with COVID-19 also still needs much research. Objective: Conduct a comprehensive study on how to diagnose, pathogenesis, therapy, and rehabilitate schizophrenia patients with COVID-19 infection Case report: Schizophrenia patients who were confirmed with COVID-19 through rRT-PCR examination were isolated at home and treated with medical treatment to overcome existing complaints, then given an injection of short-acting anti-anxiety drugs followed by maintenance therapy. Patients are treated at home by the puskesmas by involving their families and communities until they recover. Discussion: Schizophrenia patients are at risk of being infected with COVID-19 due to cognitive and behavioral disorders. Schizophrenia patients infected with COVID-19 must be given medical therapy based on complaints or negative symptoms that arise such as psychotic disorders or complaints caused by COVID-19 infection. Chlorpromazine (CPZ) can reduce psychotic disorders and hallucinations in these patients. Haloperidol can reduce positive symptoms that arise in patients so that patients can be calmer. Clobazam acts as a Gamma Amino Butyric Acid (GABA) which can reduce anxiety and agitation. Citicoline helps increase blood flow and oxygen consumption in the brain so that negative symptoms can be suppressed. Psychotherapy, family, and environmental support are needed to reduce psychosocial problems that arise due to COVID-19. Conclusions: Therapy of schizophrenia patients with COVID-19 is adjusted to psychotic problems and complaints due to COVID-19. A family-based therapy approach is needed during the isolation period to post COVID-19 health care.
Optimizing Role and Synergy of Indonesian National Police for Handling Prevention of Covid-19 Spread: A Case Study in Human Resource Development Perspective Dimas Agung Trisliatanto; Anis Byarwati; Sri Iswati; Arif Rahman Nurdianto; Fery Setiawan; Heribertus Agustinus Bilo Tena; Hendro Puspito
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15728

Abstract

Background: The rise in cases of violations and criminal acts handled by the Indonesian National Police during the COVID-19 pandemic recorded 18 cases of hoarding and increasing prices for personal protective equipment and other items. This study aims to describe and describe the optimization and synergy of the Indonesian National Police in handling the prevention of the spread of COVID-19. Method: This study used a qualitative approach with a case study method which is explored and analyzed based on the data and research information obtained. Result: This study showed that the role of Bhayangkara Fostering Public Security and Order of Indonesian National Police as the Development of Public Security and Order can be optimized to educate the public to prevent hoaxes or stigma regarding this corona virus. This synergy between the Indonesian National Police, the Indonesian Army and the Community Health Center is urgently needed to avoid data falsification and vaccine abuse in the community. Conclusion: This study concluded that the Indonesian National Police optimizes the role and synergy collaboratively with the community and the Government by relying on the Sector Police as the basis for early detection of potential security problems in the community, especially related to handling COVID-19.
Elevation of Bcl2 expression in artery spiralis of pregnant Rattus norvegicus infected with Tachyzoite of Toxoplasma gondii with hyperbaric oxygen therapy Arif Rahman Nurdianto; Aryati Aryati; Mohammad Guritno Suryokusumo; Mufasirin Mufasirin
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 3, No 2 (2019)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v3i2.2706

Abstract

ABSTRACTSpiral artery apoptosis plays a role in the process of abortion. Low Bcl2 expression found in abortion and in spiral artery. In pregnancy, Toxoplasmosis infection is found to increase apoptosis in spiral arteries. Hyperbaric Oxygen Therapy (HBOT) improves the expression of Bcl-2. This study aims to determine the effects of Hyperbaric Oxygen therapy in enhancing the expressions of Bcl2 in artery spiralis of pregnant rats infected with tachyzoite of Toxoplasma gondii. This is an experiment with a ‘randomized control group of post-test only design’ on 37 Rattus novergicus Sprague Dawley rats. Rats were divided into four groups. The group A is pregnant rats infected with 103 tachyzoites via intraperitoneal injection and received 10 sessions of HBOT 2.4 ATA in 3x30 minutes. Group B is pregnant only and received HBOT. Group C is pregnant and infected with tachyzoite but did not received HBOT. And the last, Group D is pregnant rats with no infection and did not received HBOT. Examinations of Bcl2 expressions were performed on day-5 after HBOT (twice a day). The Bcl2 expression was measured with immunohistochemistry. All data were tested with One-way ANOVA from SPSS 21.  There is an increased expression of Bcl2 spiralis artery in the Group A. There was a significant difference between Group A and Group C with a value of p=0.042. HBOT can increase the expression of Bcl2 from the spiral arteries of rats, in the provision of HBOT 2.4 ATA for 3x30 minutes, 10 times in 5 days.Keywords: Toxoplasma gondii, tachyzoite, Hyperbaric Oxygen Therapy, Bcl2, spiralis arteryCorrespondence to: didins99@gmail.com  ABSTRAK Apoptosis arteri spiralis berperan dalam proses aborsi. Ekspresi Bcl2 rendah ditemukan pada aborsi dan di arteri spiral. Pada kehamilan, infeksi Toxoplasmosis ditemukan meningkatkan apoptosis pada arteri spiralis. Terapi Oksigen Hiperbarik (HBOT) meningkatkan ekspresi Bcl-2. Ini adalah penelitian eksperimental dengan desain post-test only pada 37 hamil Rattus novergicus Sprague Dawley, maka tikus dibagi menjadi 4 kelompok. Grup A HBOT adalah tikus hamil yang terinfeksi tachyzoite yang menerima terapi 10 sesi HBOT 2.4 ATA dalam 3x30 menit; kelompok B adalah Hamil saja dan tidak mendapat HBOT; kelompok C Hamil dan terinfeksi tachyzoite T.gondii tetapi tidak menerima HBOT; dan kelompok D adalah tikus hamil normal. Setiap tikus hamil yang terinfeksi diberi 103 Tachyzoite Toxoplasma gondii melalui intraperitoneal. Pemeriksaan ekspresi Bcl2 dilakukan pada hari ke-5 setelah HBOT (dua kali sehari). Tikus terbunuh dan kadar Bcl2 Arteri spiralis diukur dengan pemeriksaan Immunohistokimia. Semua data dianalisis dengan uji ANOVA dengan Program SPSS 21. Pada studi ini menunjukkan terapi Oksigen Hiperbarik dapat meningkatkan Ekspresi Bcl2 Arteri Spiralis dengan dosis 2.4 ATA selama 3x30 menit dalam 10 sesi selama 5 hari terapi. Studi ini menyimpulkan bahwa HBOT dapat meningkatkan ekspresi Bcl2 dalam arteri spiralis, dalam pemberian HBO 2.4 ATA selama 3x30 menit dalam 10 sesi.Kata kunci: HBOT, Arteri spiralis, Bcl2, Tachyzoite Toxoplasma gondiiKorespondensi: didins99@gmail.com 
Effectiveness factors analysis of near-miss incidence referral in obstetric complications at Waras Wiris Andong General Hospital on Boyolali District Edy Mustofa; Widyasih Pritasari; Arif Rahman Nurdianto; Sunarjo Sunarjo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 2 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i2.7197

Abstract

AbstractMaternal mortality in Indonesia is still very high, and the biggest problem is obstetric complications. It is possible that the mother who has obstetric complications is safe and recovered (near miss) or died. This research was an observational analytic epidemiological study conducted to determine the effectiveness of near-miss incidence referral in obstetric complications using a cross-sectional approach. The sampling technique used was a random sampling system with 85 respondents. The effectiveness of referral affects near-miss incidence, meaning that mothers who get referral according to procedure only have a 0.107 times greater chance of not occurring near miss. Pregnant women who had a history of the disease had a risk of 0.157 times greater for the absence of near-miss than mothers who did not have a history. Pregnant women with high risk have 0.157 times no near-miss than those with low risk. Maternal antenatal examination affects the incidence of a near miss. It was found that the mother's history of illness, the risk of pregnancy owned by the mother and the effectiveness of referrals could affect the incidence of near miss in obstetric complications. In conclusion, there is an influence between the effectiveness of the referral and the near-miss incident at the Waras Wiris Andong Regional Hospital, Boyolali RegencyKeywords: referral, effectiveness, near-miss, obstetric complication
Zero Maternal Death with KECUBUNG Featured in SATE Krembung Application (Integrated Queue System) in Krembung Community Health Center in 2017 until 2018 Arif Rahman Nurdianto
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 1 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1095.835 KB) | DOI: 10.30651/jqm.v4i1.2746

Abstract

ABSTRACTThere are some special programs in Maternal and Child Health that have not yet been reached and have a bad trend like the number of Low Birth Weight (LBW), cases of stillbirth, and babies died. There was a congenital defect in babies, increased obstetric complications, and there is one case of maternal death. There were neo-complications in infants and babies. The problem that often results in the death of pregnant women is the lack of early detection at first-level facilities in the Krembung Health center. Early detection and treatment or planning in cases of high-risk pregnant women is lacking, and then we created a SATE Krembung application in 2017. Making SATE Krembung application, socializing to the community, socializing the features of KECUBUNG to report mothers at high risk, and bringing services closer to the community and to evaluate reports from residents. Activities are collected, analyzed, and processed into mature data. The number of people activities collected during the collection of data during this research from 500 users of application from 2017 until 2018. There was a decrease in maternal mortality rates to zero patients in 2017 and 2018. The use of SATE Krembung is quite effective in reducing maternal mortality to zero patients in the Krembung health center work area, but this must be improved with the development of applications. The application of SATE Krembung with KECUBUNG feature can reduce maternal mortality by empowering health cadres and the community to be aware of the environmental conditions surrounding them.Keywords                   : SATE Krembung, KECUBUNG, Maternal Death
Care, Support and Therapy Service of HIV Patients with the “SATE Krembung” Application Totok Indarto; Arif Rahman Nurdianto; Dyah Ayu Febiyanti
Jurnal Ners Vol. 14 No. 3 (2019): Special Issue
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (370.976 KB) | DOI: 10.20473/jn.v14i3.17104

Abstract

Introduction: The prevalence and incidence of HIV and AIDS in Sidoarjo is still high. Today, the adherence of patients to several ART services in Sidoarjo is quite low and varied. Therefore the researchers want to find out the effectiveness of registration using “the SATE Krembung” application in terms of service effectiveness, reducing the Lost Follow Up (LFU) and increasing patient adherence in Krembung Primary Health Care.Methods: The study was cross-sectional. The use of alternative ART service modes was done via “the SATE Krembung” application as an integrated queue system. The patients who participated in this study were HIV patients at Krembung Primary Health Care who accessed ART at Krembung Primary Health Care within the age range of 20 - 60 years. The total number of samples in this test was 16 patients.Results: Registration using “the SATE Krembung” application can reduce the waiting time for getting access to services for the HIV patients who plan on getting CST services and ART collection.Conclusion: Service effectiveness due to the use of “the SATE Krembung” application can improve service quality, reduce the Lost Follow Up (LFU) and increase the patient adherence in Krembung Primary Health Care’s ART services.
Corona Virus Disease 2019 (COVID-19) pada Wanita Hamil dan Bayi: Sebuah Tinjauan Literatur Martina Kurnia Rohmah; Arif Rahman Nurdianto
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1A (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.205 KB) | DOI: 10.36408/mhjcm.v7i1A.476

Abstract

LATAR BELAKANG: Corona Virus Disease 2019 (COVID-19) merupakan gangguan saluran pernapasan akut yang disebabkan oleh virus SARS-CoV-2 dan telah menjadi pandemi di seluruh dunia. COVID-19 telah menjangkit seluruh penduduk dunia tidak terkecuali wanita hamil. Kerentanan wanita hamil terhadap infeksi menjadi latar belakang perlunya studi tentang pengaruh COVID-19 baik pada ibu, janin, maupun bayi yang dilahirkan. TUJUAN: Studi ini bertujuan untuk mengetahui gambaran kasus COVID-19 pada ibu hamil, potensi transmisi vertikal, ada tidaknya asam nukleat SARS-CoV-2 pada ASI, pengaruh COVID-19 pada perkembangan janin, serta pengobatan ibu hamil dengan COVID-19. METODE: Studi ini mengulas dan membandingkan sumber dari artikel penelitian, laporan kasus, dan review dari jurnal internasional bereputasi. HASIL: Sebagian besar kasus COVID-19 yang ditemukan pada wanita hamil adalah tergolong kasus ringan, adanya transmisi vertikal yang rendah dibuktikan dari hasil tes sampel ibu dan bayi, minimnya kasus spontaneous abortus, kelahiran bayi prematur, kematian bayi, serta gangguan perkembangan. ASI dari ibu hamil positif COVID-19 juga cukup aman diberikan pada bayi dikarenakan kasus positif asam nukleat SARS-CoV-2 sangat minim ditemukan. KESIMPULAN: Berdasarkan studi yang komprehensif, COVID-19 pada ibu hamil sejauh ini masih cukup terkendali. Namun demikian perlu adanya tes yang menyeluruh sebab setiap individu memiliki kondisi yang berbeda satu dengan lainnya. Kata Kunci: COVID-19, janin, kehamilan, SARS-CoV-2, transmisi BACKGROUND: Corona Virus 2019 (COVID-19) is an acute respiratory tract caused by the SARS-CoV-2 virus and has become a pandemic worldwide. COVID-19 has gathered the entire world population including pregnant women. The vulnerability of pregnant women to infections is become the background was to know the effect of COVID-19 both on the mother, fetus, and baby born. OBJECTIVE: This study aims to determine the description of COVID-19 cases in pregnant women, the potential for vertical transmission, the presence or absence of nucleic acid SARS-CoV-2 in breast milk, the effect of COVID-19 on fetal development, and the treatment of pregnant women with COVID-19. METHOD: This study attempts to review and compare sources from research articles, case reports, and reviews from reputable international journals. RESULT: Most cases of COVID-19 found in pregnant women are classified as mild cases, the presence of low vertical transmission is evidenced from the results of mother and baby sample tests, the lack of cases of spontaneous abortion, premature baby births, infant deaths, and developmental disorders. Breastfeeding from COVID-19 positive pregnant women is also quite safe given to infants because positive cases of SARS-CoV-2 nucleic acid are very low. CONCLUSION: Based on a comprehensive study, COVID-19 in pregnant women so far is still quite under control. However, there needs to be a thorough test because each individual has different conditions from one another. Keywords: COVID-19, fetus, pregnancy, SARS-CoV-2, transmission
Co-Authors Acivrida Mega Charisma Acivrida Mega Charisma Amanda, Eviomitta Rizki Anis Byarwati Anwari, Farida Aryati Aryati Citra Amaniah Anhar Dimas Agung Trisliatanto Dyah Ayu Febiyanti Dyah Ayu Febiyanti Edy Mustofa Elis Anita Farida Fery Setiawan Fery Setiawan Fery Setiawan Hendro Puspito Heny Arwati Heribertus Agustinus B Tena Heribertus Agustinus Bilo Tena Heribertus Agustinus Tena Heryanti Pusparisa Hisbiyah, A’yunil Hotimah Masdan Salim I MADE MULIARTA . Jenny Sunariani Joko Sulistyo Khoirun Nisyak Kunjung Ashadi Laily Mita Andriana Laily Mita Andriana Luh Putu Ratna Sundari Martina Kurnia Rohmah Mohammad Guritno Suryokusumo Mufasirin Rizal Fauzi Nurdianto Sri Iswati Sunarjo Sunarjo Totok Indarto Widyasih Pritasari Yoes Prijatna Dachlan Yulianto Ade Prasetya, Yulianto Ade