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All Journal Jurnal NERS Jurnal Teknologi Laboratorium Molecular and Cellular Biomedical Sciences (MCBS) Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Dharma Bakti Medica Hospitalia Journal of Pharmaceutical Care Anwar Medika Jurnal Pengabdian Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan Indian Journal of Forensic Medicine & Toxicology Jurnal Olahraga Pendidikan Indonesia (JOPI)
Nurdianto, Arif Rahman
STIKES Rumah Sakit Anwar Medika
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya

 1 
Elevation of Bcl2 expression in artery spiralis of pregnant Rattus norvegicus infected with Tachyzoite of Toxoplasma gondii with hyperbaric oxygen therapy Arif Rahman Nurdianto; Aryati Aryati; Mohammad Guritno Suryokusumo; Mufasirin Mufasirin
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 3, No 2 (2019)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v3i2.2706

Abstract

ABSTRACTSpiral artery apoptosis plays a role in the process of abortion. Low Bcl2 expression found in abortion and in spiral artery. In pregnancy, Toxoplasmosis infection is found to increase apoptosis in spiral arteries. Hyperbaric Oxygen Therapy (HBOT) improves the expression of Bcl-2. This study aims to determine the effects of Hyperbaric Oxygen therapy in enhancing the expressions of Bcl2 in artery spiralis of pregnant rats infected with tachyzoite of Toxoplasma gondii. This is an experiment with a ‘randomized control group of post-test only design’ on 37 Rattus novergicus Sprague Dawley rats. Rats were divided into four groups. The group A is pregnant rats infected with 103 tachyzoites via intraperitoneal injection and received 10 sessions of HBOT 2.4 ATA in 3x30 minutes. Group B is pregnant only and received HBOT. Group C is pregnant and infected with tachyzoite but did not received HBOT. And the last, Group D is pregnant rats with no infection and did not received HBOT. Examinations of Bcl2 expressions were performed on day-5 after HBOT (twice a day). The Bcl2 expression was measured with immunohistochemistry. All data were tested with One-way ANOVA from SPSS 21.  There is an increased expression of Bcl2 spiralis artery in the Group A. There was a significant difference between Group A and Group C with a value of p=0.042. HBOT can increase the expression of Bcl2 from the spiral arteries of rats, in the provision of HBOT 2.4 ATA for 3x30 minutes, 10 times in 5 days.Keywords: Toxoplasma gondii, tachyzoite, Hyperbaric Oxygen Therapy, Bcl2, spiralis arteryCorrespondence to: didins99@gmail.com  ABSTRAK Apoptosis arteri spiralis berperan dalam proses aborsi. Ekspresi Bcl2 rendah ditemukan pada aborsi dan di arteri spiral. Pada kehamilan, infeksi Toxoplasmosis ditemukan meningkatkan apoptosis pada arteri spiralis. Terapi Oksigen Hiperbarik (HBOT) meningkatkan ekspresi Bcl-2. Ini adalah penelitian eksperimental dengan desain post-test only pada 37 hamil Rattus novergicus Sprague Dawley, maka tikus dibagi menjadi 4 kelompok. Grup A HBOT adalah tikus hamil yang terinfeksi tachyzoite yang menerima terapi 10 sesi HBOT 2.4 ATA dalam 3x30 menit; kelompok B adalah Hamil saja dan tidak mendapat HBOT; kelompok C Hamil dan terinfeksi tachyzoite T.gondii tetapi tidak menerima HBOT; dan kelompok D adalah tikus hamil normal. Setiap tikus hamil yang terinfeksi diberi 103 Tachyzoite Toxoplasma gondii melalui intraperitoneal. Pemeriksaan ekspresi Bcl2 dilakukan pada hari ke-5 setelah HBOT (dua kali sehari). Tikus terbunuh dan kadar Bcl2 Arteri spiralis diukur dengan pemeriksaan Immunohistokimia. Semua data dianalisis dengan uji ANOVA dengan Program SPSS 21. Pada studi ini menunjukkan terapi Oksigen Hiperbarik dapat meningkatkan Ekspresi Bcl2 Arteri Spiralis dengan dosis 2.4 ATA selama 3x30 menit dalam 10 sesi selama 5 hari terapi. Studi ini menyimpulkan bahwa HBOT dapat meningkatkan ekspresi Bcl2 dalam arteri spiralis, dalam pemberian HBO 2.4 ATA selama 3x30 menit dalam 10 sesi.Kata kunci: HBOT, Arteri spiralis, Bcl2, Tachyzoite Toxoplasma gondiiKorespondensi: didins99@gmail.com 
Effectiveness factors analysis of near-miss incidence referral in obstetric complications at Waras Wiris Andong General Hospital on Boyolali District Edy Mustofa; Widyasih Pritasari; Arif Rahman Nurdianto; Sunarjo Sunarjo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 2 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i2.7197

Abstract

AbstractMaternal mortality in Indonesia is still very high, and the biggest problem is obstetric complications. It is possible that the mother who has obstetric complications is safe and recovered (near miss) or died. This research was an observational analytic epidemiological study conducted to determine the effectiveness of near-miss incidence referral in obstetric complications using a cross-sectional approach. The sampling technique used was a random sampling system with 85 respondents. The effectiveness of referral affects near-miss incidence, meaning that mothers who get referral according to procedure only have a 0.107 times greater chance of not occurring near miss. Pregnant women who had a history of the disease had a risk of 0.157 times greater for the absence of near-miss than mothers who did not have a history. Pregnant women with high risk have 0.157 times no near-miss than those with low risk. Maternal antenatal examination affects the incidence of a near miss. It was found that the mother's history of illness, the risk of pregnancy owned by the mother and the effectiveness of referrals could affect the incidence of near miss in obstetric complications. In conclusion, there is an influence between the effectiveness of the referral and the near-miss incident at the Waras Wiris Andong Regional Hospital, Boyolali RegencyKeywords: referral, effectiveness, near-miss, obstetric complication
Zero Maternal Death with KECUBUNG Featured in SATE Krembung Application (Integrated Queue System) in Krembung Community Health Center in 2017 until 2018 Arif Rahman Nurdianto
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 1 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1095.835 KB) | DOI: 10.30651/jqm.v4i1.2746

Abstract

ABSTRACTThere are some special programs in Maternal and Child Health that have not yet been reached and have a bad trend like the number of Low Birth Weight (LBW), cases of stillbirth, and babies died. There was a congenital defect in babies, increased obstetric complications, and there is one case of maternal death. There were neo-complications in infants and babies. The problem that often results in the death of pregnant women is the lack of early detection at first-level facilities in the Krembung Health center. Early detection and treatment or planning in cases of high-risk pregnant women is lacking, and then we created a SATE Krembung application in 2017. Making SATE Krembung application, socializing to the community, socializing the features of KECUBUNG to report mothers at high risk, and bringing services closer to the community and to evaluate reports from residents. Activities are collected, analyzed, and processed into mature data. The number of people activities collected during the collection of data during this research from 500 users of application from 2017 until 2018. There was a decrease in maternal mortality rates to zero patients in 2017 and 2018. The use of SATE Krembung is quite effective in reducing maternal mortality to zero patients in the Krembung health center work area, but this must be improved with the development of applications. The application of SATE Krembung with KECUBUNG feature can reduce maternal mortality by empowering health cadres and the community to be aware of the environmental conditions surrounding them.Keywords                   : SATE Krembung, KECUBUNG, Maternal Death
Description of complaints/clinical symptoms and examination results of the SARS-CoV-2 rapid test in Brata Medika Laboratory Clinic Pare - Kediri in February 2021 Acivrida Mega Charisma; Arif Rahman Nurdianto; Rizal Fauzi Nurdianto; Fery Setiawan; Heribertus Agustinus Tena
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.9734

Abstract

 SARS-CoV-2 antigen rapid test is one of the examinations widely used for early detection of Covid-19 infection. Rapid test is considered to have more advantages, is faster, and is cheaper than molecular PCR testing, and more accurate than rapid antibody tests. Its weakness is especially in detecting samples with small quantities of the virus. The study was conducted using a retrospective method. The data was taken from the patient's medical record of the SARS -CoV-2 antigen rapid swab test at Brata Medika Pare Clinical Laboratory for the period of February 2021. Data inclusion criteria including the examination, complete identity, results of anamnesis examination and rapid test examinations. Data were analyzed in a tabular form containing frequency and percentage. There were 18 (22.5%) patients with positive SARS-CoV-2antigen rapid swab test results, 16 (89%) with complaints/symptoms, and 2 (11%) without complaints/symptoms. Meanwhile, 62 (77.5%) were found with negative SARS-CoV-2 antigen rapid swab test results where 18 (29.0%) were patients with complaints/symptoms and 44 (71.0%) were patients without complaints/symptoms. The high percentage of negative SARS-CoV-2 antigen rapid swab test results in patients with complaints/symptoms (29.0%), it is recommended that a confirmatory examination with the molecular PCR test be carried out. 
Co-Authors Acivrida Mega Charisma Acivrida Mega Charisma Amanda, Eviomitta Rizki Anis Byarwati Anwari, Farida Aryati Aryati Citra Amaniah Anhar Dimas Agung Trisliatanto Dyah Ayu Febiyanti Dyah Ayu Febiyanti Edy Mustofa Elis Anita Farida Fery Setiawan Fery Setiawan Fery Setiawan Hendro Puspito Heny Arwati Heribertus Agustinus B Tena Heribertus Agustinus Bilo Tena Heribertus Agustinus Tena Heryanti Pusparisa Hisbiyah, A’yunil Hotimah Masdan Salim I MADE MULIARTA . Jenny Sunariani Joko Sulistyo Khoirun Nisyak Kunjung Ashadi Laily Mita Andriana Laily Mita Andriana Luh Putu Ratna Sundari Martina Kurnia Rohmah Mohammad Guritno Suryokusumo Mufasirin Rizal Fauzi Nurdianto Sri Iswati Sunarjo Sunarjo Totok Indarto Widyasih Pritasari Yoes Prijatna Dachlan Yulianto Ade Prasetya, Yulianto Ade