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All Journal Jambi Medical Journal "Jurnal Kedokteran dan Kesehatan" Syntax Literate : Jurnal Ilmiah Indonesia MEDIC MEdical Dedication Electronic Journal Scientific of Environmental Health And Diseases Journal of Medical Studies
Iskandar, Mirna Marhami
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Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Other

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Journal : Jambi Medical Journal "Jurnal Kedokteran dan Kesehatan"

 1 
KORELASI AMBANG NYERI TEKAN OTOT DENGAN DERAJAT NYERI DAN DISABILITAS PADA PENGENDARA OJEK ONLINE YANG MENDERITA NYERI PUNGGUNG BAWAH MIOFASIAL Attiya Istarini; Mirna Marhami Iskandar
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 10 No. 4 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.542 KB) | DOI: 10.22437/jmj.v10i4.21478

Abstract

Background: Online taxi rider is one of the jobs that requires the rider to be in a sitting or flexed position for a long time. An ergonomic position at work affects the pressure and tension of the lower back muscles. Continuous muscle pressure and strain has the risk of causing myofascial low back pain (LBP) in Online taxi riders. Objectives: This study aims to determine the correlation between the pressure threshold and the degree of pain and degree of disability in online motorcycle taxi drivers who suffer from LBP. Methods: This study is an observational study with a cross-sectional design. All samples were examined for muscle pressure at trigger points at paraspinal mucle in the lower back area using an Algometer. Assessment of the degree of pain was carried out using the Numeric Pain Scale instrument and the degree of disability was assessed by the Oswetri Disability Index. Results: In this study, 30 online Online taxi riders were found with complaints of myofascial low back pain with an average pressure threshold that causes pain at the trigger point of 5.03 ± 1.3 kgf. After conducting bivariate analysis with the Pearson test, no significant correlation was found between the threshold of muscle tension and the degree of pain and degree of disability of Online taxi riders who suffer from LBP (p>0.05). Conclusion: There is no correlation between the threshold of muscle pressure and the degree of pain and disability of Online taxi rider. Keywords: threshold of tenderness, myofacial lower back pain, online taxi riders
EVALUASI SURVIVIN DAN MAMMALIAN TARGET OF RAPAMYCIN COMPLEX-1 SERTA KORELASINYA PADA AKNE VULGARIS Mirna Marhami Iskandar; Sri Yusfinah Masfah Hanum; Erny Kusdiah; Rima Rahmi Putri Harahap; Jelica Oktaviani
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v11i1.21121

Abstract

Background: Survivin is a member of the apoptosis inhibitory protein family, a protein molecule important for the regulation of mitosis and inhibition of apoptosis and also plays a role in certain physiological processes and pathological conditions such as carcinogenesis in human cells/organs. Several studies have shown that survivin plays a role in the pathogenesis of acne vulgaris and post-inflammatory acne scarring. Mammalian target of rapamycin complex-1 (mTORC1) is a regulator of cell growth, proliferation and metabolic homeostasis, and mTORC1 signaling regulates survivin via the kinase pathway. Objectives: This study aimed to assess the correlation of survivin levels with mTORC1 and the severity of acne vulgaris. Methods: This research was a cross-sectional study. Venous blood samples of mild, moderate, and severe AV patients were 20 people each, ELISA examination was performed. Result: The results showed that serum levels of survivin and mTORC1 had a correlation with the severity of AV (p<0.05), while the correlation between survivin and mTORC1 was not significant (p>0.05). Conclussion: This study proves that increased survivin and mTORC1 are associated with increased severity of acne vulgaris, but the relationship between survivin and mTORC1 needs further investigation. Key words: survivin, mammalian target of rapamycin complex-1, akne vulgaris
Co-Authors Armaidi Darmawan Attiya Istarini Attiya Istarini Ave Olivia Rahman Citra Maharani Erny Kusdiah Erny Kusdiyah Fairuz Fairuz Fairuz Quzwain Fenny Merselly Hanina Hanina Hanina, Hanina Hasna Dewi Herlambang Herlambang Ima Maria Jelica Oktaviani Lipinwati Lipinwati Lipinwati Mara Imam Taufiq Siregar Maria Estela Karolina Mauli Datul Hasanah Miftahul Jannah Miftahurrahmah Miftahurrahmah, Miftahurrahmah Nindya Aryanty Nindya Aryanty Nurhanisah Dalimunthe Patrick Wiliam Gading Patrick William Gading Patrick William Gading Putri Sari Wulandari Putri Sari Wulandari Rima Rahmi Putri Harahap Sri Yusfinah Masfah Hanum Suzan, Raihanah Tarawifa, Susan Wahyu Indah Dewi Aurora Winiesti Melani Putri