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All Journal Jurnal Saintika Medika Biomedika Herb-Medicine Journal Medica Arteriana (Med-Art) Lontara: Journal of Health Science and Technology Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika
Devi Usdiana Rosyidah
Universitas Muhammadiyah Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

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HUBUNGAN PENGETAHUAN TENTANG HIPERTENSI DENGAN PENGENDALIAN TEKANAN DARAH PADA PASIEN HIPERTENSI DI POLIKLINIK PENYAKIT DALAM RSUD DR.MOEWARDI SURAKARTA Wulansari, Jayanti; Ichsan, Burhannudin; Usdiana, Devi
Biomedika Vol 5, No 1 (2013): Biomedika Februari 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Nowadays, hypertension becomes the main problem in the world. Uncontrolled hypertension remains the main health problem. One of the problems that cause uncontrolled blood pressure is the less knowledge of hypertension. Patient’s knowledge and awareness in hypertension is the important factor to control the blood pressure. The aim of this study is to know the relation between hypertension knowledge and blood pressure restraint to hypertension patient in the Internist Polyclinic RSUD dr.Moewardi Surakarta. This research used analytic survey method in cross sectional approach. It took 57 sample of hypertension patient. It used purposive sampling technique. This research used Chi Square statistic test. In forty two patients (73,7%) with well-knowledge, 31 patients hypertension (73,8%) have controlled-blood pressure and uncontrolled blood pressure is 11 patients (26,2%). Whereas, in 15 patients (26,3%) who has lack-knowledge found controlled-blood pressure in 6 patients (40%), and uncontrolled blood pressure in 9 patients (60%). There was not found less-knowledge patients. The Chi Square test found signifi cance probability (p)= 0,019. There is relation between hypertension knowledge and controlling blood pressure.Keywords: knowledge, hypertension, controlling blood pressure
HUBUNGAN TINGKAT PENGETAHUAN TENTANG PENYAKIT DM DENGAN PENGENDALIAN KADAR GLUKOSA DARAH PADA PASIEN DM TIPE II DI RSU PKU MUHAMMADIYAH SURAKARTA Perdana, Ananda Asriany; Ichsan, Burhannudin; Rosyidah, Devi Usdiana
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The level of DM knowladge with blood glucose controll was instrument to help diabetic patients did the management of diabetes. Diabetic patients who had more and better informations about DM, than they changed their life style, that could controll their disease. So, they would have longer and better live. This research was observational analytic research with cross sectional approach. The sample was 33 diabetic patients who cared their disease in RSU PKU Muhammadiyah Surakarta and who had ful lled the predeterminated criteria, it was taking with the purposive sampling technique. The research instrument used the level of DM knowladge quesioner and medical record. From the statistical calculation, it was obtained that P value = 0,042. It could be concluded that there was signi cant the relationship between the level of DM knowladge with blood glucose controll of type 2 diabetic patients. Pasients who had high level knowladge would have good blood glucose controll.Key Words : Level Knowladge, Diabetes Melitus of Type 2, Blood Glucose
HUBUNGAN PEKERJA BASAH DENGAN KEJADIAN DERMATITIS KONTAK AKIBAT KERJAPADA PETUGAS KESEHATAN DI RUMAH SAKIT X TANJUNG, TABALONG, KALIMANTAN SELATAN Anshar, Rizadin; Pramuningtyas, Ratih; Usdiana, Devi
Biomedika Vol 8, No 2 (2016): Biomedika Agustus 2016
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v8i2.2913

Abstract

Prevalensi dermatitis kontak akibat kerja (DKAK) di dunia terbilang tinggi. Kontak kulit terhadap iritan atau alergen di tempat kerja dapat mengakibatkan terjadinya DKAK.Petugas kesehatan merupakan salah satu profesi yang berisiko terjadinya DKAK. Hasil survei pendahuluan yang dilakukan di RS X, Tanjung, didapatkan 6 orang menderita DKAK dari 20 petugas kesehatan yang diwawancarai. Penelitian ini bertujuan untuk mengetahui hubungan antara pekerjaan basah dengan kejadian DKAK pada petugas kesehatan. Desain penelitian menggunakan metode observasional analitik dengan pendekatan cross sectional. Jumlah responden penelitian sebanyak 80 petugas kesehatan. Teknik pengambilan sampel menggunakan simple random sampling. Data primer dianalisis dengan uji Chi Square menggunakan program SPSS 17.Hasil penelitian menunjukkan bahwa nilai p = 0,001 (p < 0,05) yang menunjukkan bahwa terdapat hubungan yang bermakna antara pekerjaan basah dengan kejadian DKAK.Terdapat hubungan yang bermakna antara pekerjaan basah dengan kejadian DKAK pada petugas kesehatan di RS X Tanjung, Tabalong, Kalimantan Selatan. Kata Kunci : Pekerja Basah, Petugas Kesehatan, Dermatitis Kontak Akibat Kerja
UJI EFEK HAMBATAN ATORVASTATIN TERHADAP PEMBENTUKAN SKAR HIPERTROFI PADA KELINCI NEW ZEALAND (Kajian terhadap morfologi klinis ketinggian jaringan skar, Scar Elevation Index, kepadatan kolagen, dan ekspresi VEGF) Rosyidah, Devi Usdiana; Astuti, Indwiani; Widyarini, Sitarina
Biomedika Vol 10, No 1 (2018): Biomedika Februari 2018
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v10i1.5848

Abstract

Skar hipertrofi dan keloid bagian dari jaringan parut patologis yang insiden kejadiannya masih tinggi. Keduanya mengganggu secara estetik, fisiologik, psikologik, dan sering tumbuh kembali setelah pengobatan. Belum ada terapi standar baku emas untuk skar hipertrofi dan keloid. Efek pleiotropik statin berpotensi sebagai anti skar baru. Penelitian ini bertujuan untuk mengetahui efek hambatan pembentukan skar hipertrofi dengan pemberian salep atorvastatin pada model luka skar di telinga kelinci New Zealand. Kelinci New Zealand usia 4-6 bulan (n=29) dilakukan randomisasi kedalam lima kelompok. Setelah aklimatisasi 1 minggu, dilakukan pembuatan luka model skar hipertrofi pada kedua telinga kelinci dengan punch biopsy (d=8 mm). Jumlah luka 2 buah di masing- masing telinga kanan dan kiri. Pada hari ke-7 setelah punch biopsy, kelompok I, II, III dioles salep atorvastatin dengan konsentrasi masing-masing 5%, 10%, dan 20%. Kelompok IV dioles salep clobetasol propionate 0,05% sebagai kontrol positif, dan kelompok V dioles dengan basis salep (lanolin vaselin 1:1) sebagai kontrol negatif. Frekuensi pengolesan salep pada luka ditelinga kelinci tersebut 1 kali/hari, dengan lama pengolesan selama 50 hari kedepan. Setiap hari dilakukan pengukuran morfologi klinis ketinggian skar. Pada hari ke 56 setelah punch biopsy, dilakukan penilaian akhir morfologi klinis jaringan skar hipertrofi, kemudian kelinci didekapitasi, diambil jaringan skar hipertrofi kemudian dibuat preparat histologis (HE, Von Gieson) dan imunohistokimia (VEGF). Salep atorvastatin 5% mampu menghambat pembentukan skar hipertrofi pada telinga kelinci New Zealand dengan nilai median skoring ketinggian jaringan skar sebesar 1(1-3), nilai SEI rata-rata sebesar 1,49±0,37 mm, dan nilai ekspresi VEGF sebesar 12,71±4,27%. Salep atorvastatin 5% mempunyai potensi untuk dikembangkan sebagai obat penghambat pembentukan skar hipertrofi baru dengan mekanisme penghambatan terhadap VEGF. Untuk pengembangan obat ini diperlukan penelitian lebih lanjut mengenai kapan waktu yang paling tepat mulai dioleskan salep atorvastatin setelah terjadi luka berisiko terbentuknya skar hipertrofi. Kata kunci: Atorvastatin, skar hipertrofi, VEGF, telinga kelinci.
EFEK HIPOLIPIDEMIK EKSTRAK ETANOL LIDAH BUAYA (Aloe vera L) PADA TIKUS PUTIH JANTAN MODEL HIPERKOLESTEROLEMIA Rosyidah, Devi Usdiana; Primayanti, Yustika Qasthari; Satriyani, Oktein
Biomedika Vol 11, No 1 (2019): Biomedika Februari 2019
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v11i1.7662

Abstract

Hyperlipidemia was a national health problem related to cardiovascular disease. The increasing public interest in natural materials as a management of hyperlipidemia research with natural ingredients. Aloe vera L. extract contained acemannan (glucomannan) and cellulose which could reduce lipid profiles. This aim of this study was to determine the effect of Aloe vera extract on the lipid profile of hypercholesterolemic modelling wistar male rats. This study used a laboratory experimental research design. The method was pre and post test with control group design. This study used 25 male Rattus norvegicus induced by high-fat feed for 14 days. Subjects were divided into 5 groups: negative control group (aquadest), positive control group (cholestiramine 0.2mg/200gBB/day), extract of Aloe vera L dose 0.3g/200gBB/day, extract of Aloe vera L dose 0.6g/200gBB/day, extract of Aloe vera L dose 1.2g/200gBB/day. Measurement of lipid profile levels was carried out on the 7th day, 21st day, and 35th day. Shapiro-Wilk test and Lavene test showed all data were normal and homogenous. The Paired t-Test results obtained p= 0,000. One Way Anova test with triglyceride showed p< 0,05. The LSD test showed for the aquadest group triglyceride levels with 70% ethanol extract Aloe vera L dose 0.3g/200gBB/day, 0.6g/200gBB/day, and 1.2g/200gBB/day were p= 0.012, p= 0,000 and p= 0,000 respectively. Least significance different test for LDL cholesterol and total cholesterol in the aquadest group with 70% ethanol extract of Aloe vera L only at a dose of 1.2g /200gBB/day were significantly different with a value of p= 0.006 and p= 0.001. The conclusion was ethanol extract 70% Aloe vera L dose 1.2g/ 200gBB/day could reduce lipid profile such as triglyceride levels, LDL cholesterol and total cholesterol in hypercholesterolemic modelling wistar male rats.Keywords: Aloe Vera L., Lipid Profile, Glucomannan
HUBUNGAN TINGKAT PENGETAHUAN TENTANG PENYAKIT DM DENGAN PENGENDALIAN KADAR GLUKOSA DARAH PADA PASIEN DM TIPE II DI RSU PKU MUHAMMADIYAH SURAKARTA Perdana, Ananda Asriany; Ichsan, Burhannudin; Rosyidah, Devi Usdiana
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v5i2.265

Abstract

The level of DM knowladge with blood glucose controll was instrument to help diabetic patients did the management of diabetes. Diabetic patients who had more and better informations about DM, than they changed their life style, that could controll their disease. So, they would have longer and better live. This research was observational analytic research with cross sectional approach. The sample was 33 diabetic patients who cared their disease in RSU PKU Muhammadiyah Surakarta and who had ful? lled the predeterminated criteria, it was taking with the purposive sampling technique. The research instrument used the level of DM knowladge quesioner and medical record. From the statistical calculation, it was obtained that P value = 0,042. It could be concluded that there was signi? cant the relationship between the level of DM knowladge with blood glucose controll of type 2 diabetic patients. Pasients who had high level knowladge would have good blood glucose controll.Key Words : Level Knowladge, Diabetes Melitus of Type 2, Blood Glucose
HUBUNGAN PENGETAHUAN TENTANG HIPERTENSI DENGAN PENGENDALIAN TEKANAN DARAH PADA PASIEN HIPERTENSI DI POLIKLINIK PENYAKIT DALAM RSUD DR.MOEWARDI SURAKARTA Wulansari, Jayanti; Ichsan, Burhannudin; Usdiana, Devi
Biomedika Vol 5, No 1 (2013): Biomedika Februari 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v5i1.271

Abstract

Nowadays, hypertension becomes the main problem in the world. Uncontrolled hypertension remains the main health problem. One of the problems that cause uncontrolled blood pressure is the less knowledge of hypertension. Patient?s knowledge and awareness in hypertension is the important factor to control the blood pressure. The aim of this study is to know the relation between hypertension knowledge and blood pressure restraint to hypertension patient in the Internist Polyclinic RSUD dr.Moewardi Surakarta. This research used analytic survey method in cross sectional approach. It took 57 sample of hypertension patient. It used purposive sampling technique. This research used Chi Square statistic test. In forty two patients (73,7%) with well-knowledge, 31 patients hypertension (73,8%) have controlled-blood pressure and uncontrolled blood pressure is 11 patients (26,2%). Whereas, in 15 patients (26,3%) who has lack-knowledge found controlled-blood pressure in 6 patients (40%), and uncontrolled blood pressure in 9 patients (60%). There was not found less-knowledge patients. The Chi Square test found signifi cance probability (p)= 0,019. There is relation between hypertension knowledge and controlling blood pressure.Keywords: knowledge, hypertension, controlling blood pressure
The Effectiveness Of Squeeze Of Sambiloto (Andrographis Paniculata) Leaves On The Mortality Of Larvae Aedes Aegypti Graffico Eryza Oldiara; Riandini Aisyah; Safari Wahyu Jatmiko; Devi Usdiana Rosyidah; Rochmadina Suci Bestari
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11120

Abstract

Dengue hemorrhagic fever has become a deadly disease since 2013. Dengue fever is a disease caused by dengue virus transmitted to humans through the bite of the Aedes aegypti. Eradication using chemical larvacides still has many disadvantages so that natural larvacides from plants are needed, one of which is larvacide from the squeeze of the sambiloto (Andrographis paniculata) leaves. The squeeze of the sambiloto leaf (Andrographis paniculata) contains flavonoids, alkaloids, tannins and saponins which have natural larvacidal activity. This research aims to determine the killing power of the squeeze of sambiloto (Andrographis paniculata) leaves against Aedes aegypti larvae and determine the most effective concentration as larvicide. This research was experimental laboratory with post test only controlled group design method. There are 600 instar III Aedes aegypti Larvae randomly divided into 6 groups (5%, 10%, 15%, 20%, aquadest and abate). Using 4 repetitions each group was observed every 6 hours for 24 hours. Based on the results of the Kruskal-Wallis non-parametric statistical test obtained p-value = 0,001 which means there are significant differences in larvicidal effects between groups. The concentration of 15% and 20% are the most effective in killing the larvae of Aedes aegypti.
Effectivity Test of Tobacco Leaf (nicotiana tabacum l.) 96% Ethanol Extract on Culex Quinquefasciatus Larvae Mortality Ahmad Rosid Nasrulloh Arifqi; Devi Usdiana Rosyidah; Listyana Masyita Dewi; E. M. Sutrisna
Saintika Medika Vol. 16 No. 2 (2020): December 2020
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol16.SMUMM2.11403

Abstract

Culex quinquefasciatus acts as a vector for Filariasis disease. The transmission of this disease can be prevented by cutting the life cycle of these mosquitoes at the larvae phase. Tobacco leaf contains an alkaloid, flavonoid, essential oil, saponin, and tannin which can kill Culex quinquefasciatus larvae. This study is a laboratory experiment with a post-test only controlled group design. This study used the larvae of Culex quinquefasciatus third-instar larvae. Six hundreds larvae were divided into 6 groups and 4 repetitions (each consisted of 25 larvae), i.e. negative control (distilled water + CMC), tobacco leaf ethanol extract (EEDT) with 0.025%; 0.05%; 0.075% and 0.1% doses and positive control (temephos). The number of dead larvae was counted at 6, 12, 18, and 24 hours after treatment. The results of the Kruskal-Wallis test showed p-value = 0.000, followed by the Mann-Whitney Post-hoc test, which resulted in all four doses of EEDT significantly differed compared to the negative control. However, 0.1% concentration was insignificantly different than the positive control. This showed that the ethanol extract of Nicotiana tabacum L. was effective in killing Culex quinquefasciatus larvae and EEDT with 0.1% concentration had the same potential as temephos as a larvicide.  
UJI EFEK HAMBATAN ATORVASTATIN TERHADAP PEMBENTUKAN SKAR HIPERTROFI PADA KELINCI NEW ZEALAND (Kajian terhadap morfologi klinis ketinggian jaringan skar, Scar Elevation Index, kepadatan kolagen, dan ekspresi VEGF) Devi Usdiana Rosyidah; Indwiani Astuti; Sitarina Widyarini
Biomedika Vol 10, No 1 (2018): Biomedika Februari 2018
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v10i1.5848

Abstract

Skar hipertrofi dan keloid bagian dari jaringan parut patologis yang insiden kejadiannya masih tinggi. Keduanya mengganggu secara estetik, fisiologik, psikologik, dan sering tumbuh kembali setelah pengobatan. Belum ada terapi standar baku emas untuk skar hipertrofi dan keloid. Efek pleiotropik statin berpotensi sebagai anti skar baru. Penelitian ini bertujuan untuk mengetahui efek hambatan pembentukan skar hipertrofi dengan pemberian salep atorvastatin pada model luka skar di telinga kelinci New Zealand. Kelinci New Zealand usia 4-6 bulan (n=29) dilakukan randomisasi kedalam lima kelompok. Setelah aklimatisasi 1 minggu, dilakukan pembuatan luka model skar hipertrofi pada kedua telinga kelinci dengan punch biopsy (d=8 mm). Jumlah luka 2 buah di masing- masing telinga kanan dan kiri. Pada hari ke-7 setelah punch biopsy, kelompok I, II, III dioles salep atorvastatin dengan konsentrasi masing-masing 5%, 10%, dan 20%. Kelompok IV dioles salep clobetasol propionate 0,05% sebagai kontrol positif, dan kelompok V dioles dengan basis salep (lanolin vaselin 1:1) sebagai kontrol negatif. Frekuensi pengolesan salep pada luka ditelinga kelinci tersebut 1 kali/hari, dengan lama pengolesan selama 50 hari kedepan. Setiap hari dilakukan pengukuran morfologi klinis ketinggian skar. Pada hari ke 56 setelah punch biopsy, dilakukan penilaian akhir morfologi klinis jaringan skar hipertrofi, kemudian kelinci didekapitasi, diambil jaringan skar hipertrofi kemudian dibuat preparat histologis (HE, Von Gieson) dan imunohistokimia (VEGF). Salep atorvastatin 5% mampu menghambat pembentukan skar hipertrofi pada telinga kelinci New Zealand dengan nilai median skoring ketinggian jaringan skar sebesar 1(1-3), nilai SEI rata-rata sebesar 1,49±0,37 mm, dan nilai ekspresi VEGF sebesar 12,71±4,27%. Salep atorvastatin 5% mempunyai potensi untuk dikembangkan sebagai obat penghambat pembentukan skar hipertrofi baru dengan mekanisme penghambatan terhadap VEGF. Untuk pengembangan obat ini diperlukan penelitian lebih lanjut mengenai kapan waktu yang paling tepat mulai dioleskan salep atorvastatin setelah terjadi luka berisiko terbentuknya skar hipertrofi. Kata kunci: Atorvastatin, skar hipertrofi, VEGF, telinga kelinci.
Co-Authors Afif Iqbal Hibatullah Ahmad Rosid Nasrulloh Arifqi Ananda Asriany Perdana Ananda Asriany Perdana, Ananda Asriany Anshar, Rizadin Burhannudin Ichsan Burhanuddin Ichsan E. M. Sutrisna Em Sutrisna Erika Diana Risanti Erna Herawati Farid Santya Budi Febrian Dwi Cahyo Graffico Eryza Oldiara Ilham Fahrudin Indra Nuroso Indwiani Astuti Indwiani Astuti Iqbal Maulana Jayanti Wulansari Jayanti Wulansari, Jayanti Listyana Masyita Dewi Oktein Satriyani Primayanti, Yustika Qasthari Ratih Pramuningtyas Retno Sintowati - Riandini Aisyah Rizadin Anshar Rochmadina Suci Bestari Safari Wahyu Jatmiko Satriyani, Oktein Sitarina Widyarini Syahrun El Mubaraq Talitha Ulima Santoso Tanjung Anitasari Indah Kusumaningrum Tri Agustina Yustika Qasthari Primayanti Zahra Hafizha Fitria Anam