Article Per Year (5 Year)
p-Index From 2019 - 2024
2.715
P-Index
This Author published in this journals
All Journal Medicina COPING (Community of Publishing in Nursing) E-Jurnal Medika Udayana Jurnal Kesehatan Andalas MNJ (Malang Neurology Journal) Universa Medicina Bali Journal of Anesthesiology Jurnal Penelitian Pertanian Tanaman Pangan Callosum Neurology Journal : Jurnal Berkala Neurologi Bali ISM (Intisari Sains Medis) : Jurnal Kedokteran Majalah Kedokteran Neurosains Bali Anatomy Journal Cermin Dunia Kedokteran
I Made Oka Adnyana
Department Of Neurology, Faculty Of Medicine, Udayana University/Sanglah General Hospital, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

Published : 28 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Bali Anatomy Journal

 1 
TNF-α and IL-1 in migraine, current knowledge and future perspectives: literature review Putri Rossyana Dewi; I Made Oka Adnyana; I Putu Eka Widyadharma
Bali Anatomy Journal Vol 3 No 2 (2020): Bali Anatomy Journal (BAJ)
Publisher : Department of Anatomy, Medical Faculty, Universitas Udayana, Bali-Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36675/baj.v3i2.45

Abstract

Background: Migraine is closely related to physical and biopsychosocial problems on human. The increasing number of migraine cases can affect the quality of life and increasing financial burden. Aim: The study aims to simply review the presentation of TNF- α and IL-1 in migraine mechanisms as well as the perspective of their future agenda. Review: The characteristics of migraine symptoms include unilateral and pulsating headaches precede by fatigue, irritability, decrease of concentration, and daytime sleepiness. Vascular and neurovascular theory are previous theory about the pathophysiology of migraine. Recent knowledge state that cortical spreading depression is the underlying mechanism of the aura and migraine. Other literatures showed that neurogenic inflammation also play a role in migraine particularly mast cells. Mast cells degranulate pro-inflammatory cytokines including TNF-α and IL-1, chemokines, and other substances. The involvement of TNF-α and IL-1 in migraine will be discussed in this review.
Characteristics, comorbidities, and outcomes of acute ischemic stroke cases treated with thrombolysis in Sanglah General Hospital Bali: A case series Ida Ayu Sri Indrayani; Valentina Tjandra Dewi; Ida Bagus Kusuma Putra; I Gusti Ngurah Ketut Budiarsa; Nyoman Angga Krishna Pramana; Kumara Tini; I Made Oka Adnyana
Bali Anatomy Journal Vol 4 No 1 (2021): Bali Anatomy Journal (BAJ)
Publisher : Department of Anatomy, Medical Faculty, Universitas Udayana, Bali-Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36675/baj.v4i1.56

Abstract

Background: Intravenous recombinant tissue plasminogen activator (IV rt-PA) in eligible patient groups is the main therapy for acute phase ischemic stroke within 4.5 hours of symptom onset which can significantly improve functional outcome. However, not all patients who underwent thrombolysis had a good outcome. Case: We report a series of seven patients cases undergoing IV thrombolysis from 2019-2020 at Sanglah General Hospital with varying baseline conditions and outcomes. Most cases benefit from IV rt-PA administration. There was one case with a poor outcome and one case with a rare anaphylactic reaction following alteplase administration. Conclusion: The number of thrombolysis procedure which is the main treatment of acute ischemic stroke is quite small. It is necessary to increase public education and understanding regarding the rapid response to acute stroke symptoms. Most of the cases yielded good outcomes while several cases had unfavorable outcomes related to variable factors. Hemorrhagic transformation does not directly associate with poor outcome. Clinicians also need to increase awareness of allergic reactions risk to rt-PA and provide prompt treatment.
Co-Authors Adriana Marsha Yolanda Agus Antara, Agus Anak Agung Ayu Putri Laksmidewi Anak Agung Ayu Suryapraba Anak Agung Bagus Ngurah Nuartha Anna Marita Gelgel Arimbawa, I Komang Ariswanda, I Gusti Agung Gede Artini, Ni Made Yuli Bhaskoro Adi Widie Nugroho, Bhaskoro Adi Widie Desak Made Widyanthari Devi, Gusti Ayu Putu Giti Livia Dewa Putu Gede Purwa Samatra Eric Hartono Tedyanto Haditya, Yogi Hakim, Lukman I Gusti Ngurah Ketut Budiarsa I Putu Eka Widyadharma I.A. Sri Indrayani Ida Ayu Made Vera Susiladewi Ida Ayu Sri Indrayani Ida Ayu Sri Wijayanti Ida Bagus Kusuma Putra Ida Bagus Kusuma Putra IGN Budiarsa Kesanda, I Made Phala Kumara Tini Laksmidwei, A A A Putri Lim, Demetria Jesica Lina Kamelia Ni Made Susilawathi Ni Made Yuli Artini Ni Putu Ayu Putri Mahadewi Ni Putu Mira Kardila Dewi Ni Putu Witari Nyoman Angga Krishna Pramana P. Gde Daniswara Raditya Rahman Purwanto, Oky Dwi Putri Rossyana Dewi Putu Bagus Bramanthana Tirtha Putu Diva Pranitha Putu Gede Sudira Richard Suherlim Risky Ilona Saputra Suryamulyawan, Kadek Adi Thomas Eko Purwata Valentina Tjandra Dewi