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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. ULUL ALBAB Psikoislamika : Jurnal Psikologi dan Psikologi Islam Jurnal Ekonomi Modernisasi Berkala Ilmu Kesehatan Kulit dan Kelamin Majalah Kesehatan FKUB NUR EL-ISLAM : Jurnal Pendidikan dan Sosial Keagamaan Al-Madrasah: Jurnal Ilmiah Pendidikan Madrasah Ibtidaiyah Gulawentah:Jurnal Studi Sosial TSAQAFAH JURNAL PANGAN Ulumuna: Jurnal Studi Keislaman Norma Islamic Banking : Jurnal Pemikiran dan Pengembangan Perbankan Syariah Indonesian Journal of Management Science Journal of General-Procedural Dermatology & Venereology Indonesia
AUNUR ROFIQ
Fakultas Ilmu Budaya Universitas Brawijaya
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Kadar TNF- Lesi Kulit dengan Derajat Keparahan Psoriasis Vulgaris Budini, Sulamsih Sri; Cholis, M. Cholis; Rofiq, Aunur
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (253.55 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-7

Abstract

Latar belakang: Peranan TNF- dalam patogenesis terjadinya lesi kulit pada psoriasis sudah banyak diteliti, termasuk pemakaian terapi biologis pada psoriasis dengan bahan yang menghambat TNF- dan sel T. Kegunaan TNF- serum sebagai biomarker aktifitas penyakit psoriasis memberi hasil yang tidak konsisten baik dalam jumlah absolutnya maupun hubungannya dengan respon hasil pengobatan. Tujuan: Mengevaluasi kadar TNF- lesi kulit dengan derajat keparahan penyakit psoriasis. Metode: Desain penelitian adalah potong lintang analitik observasional dengan jumlah sampel duapuluh lima penderita psoriasis vulgaris yang datang ke poli rawat jalan RSUD Dr Saiful Anwar Malang sesuai kriteria inklusi dan eksklusi. Diagnosis ditegakkan berdasarkan pemeriksaan klinis dan histopatologis. Derajat keparahan dievaluasi dengan skor Psoriasis Area Severity Index (PASI), yaitu <10 ringan; 10-20 sedang; dan >20 berat. Kadar TNF- lesi kulit di ukur dengan metode ELISA. Kadar TNF- lesi kulit ditentukan dengan menghitung nilai rerata pada masing-masing derajat keparahan. Data diolah dengan program SPSS versi 14, hubungan antara kadar TNF- lesi kulit dengan derajat keparahan penyakit diuji dengan menggunakan rumus uji korelasi Spearman. Hasil: Didapatkan rerata kadar TNF- lesi kulit 135,00 + 30,04 pada PASI ringan, 229,40 + 38,06 pada PASI sedang, 258,00 + 53,04 pada PASI berat. Rerata skor PASI penderita psoriasis vulgaris pada derajat ringan 8,57 + 0,57, sedang 16,46 + 3,08 dan berat 28,21 + 10,86. Simpulan: Makin tinggi kadar TNF- makin bertambah pula derajat keparahan psoriasis vulgaris. Kata kunci: psoriasis, TNF-, PASI, derajat keparahan.
Serum Level Of Dehydroepiandrosterone Sulphate Hormone at Various Acne Vulgaris Severity Miryana, Windy; Cholis, Mohammad; Rofiq, Aunur; Sugiman, Tantari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.776 KB) | DOI: 10.20473/bikkk.V26.3.2014.1-8

Abstract

Background: The pathogenesis of acne vulgaris (AV) is multifactorial. Hormone dehydroepiandrosterone sulfate (DHEAS) is an androgen hormone important in the initial formation of AV in women, namely the development and differentiation of sebaceous glands, which are mostly found in human blood serum. Research looking at differences in hormone levels in serum DHEAS between various degrees of severity of AV in women has not been done. Purpose: To measure whether there was a difference of serum level of DHEAS hormone at various AV severity in women. Methods: The study design was a cross-sectional analytic observational, with ninety subjects, women, by using inclusion and exclusion criterias. The diagnosis was based on clinical examination. AV severity was categorized into 3 groups, mild, moderate, and severe, that based on Combined Acne Severity Index by Lehmann. Serum level of DHEAS hormone was measured with ELISA method. The difference of serum level of DHEAS hormone at various AV severity was analyzed with non-parametric statistical test Kruskal-Wallis and Mann-Whitney. Results: The mean serum level of DHEAS hormone in women with mild AV is 1076.01±257.89 pg/ml, in moderate AV is 1971.95±272.73 pg/ml, and in severe AV is 19678.22±33536.38 pg/ml. Conclusion: There were significant difference of serum level of DHEAS hormone between women with mild and moderate AV, mild and severe AV, and moderate and severe AV (p value < 0.05), but still below from normal level.Key words: acne vulgaris, women, observasional analytic, serum level DHEAS, severity grading.
HUBUNGAN ANTARA KADAR HORMON DEHYDROEPIANDROSTERONE SULFATE (DHEAS) SERUM DENGAN AKTIVITAS PENYAKIT URTIKARIA KRONIS PADA PEREMPUAN Brahmanti, Herwinda; Rofiq, Aunur; Cholis, Mochammad
Majalah Kesehatan FKUB Vol 4, No 4 (2017): MAJALAH KESEHATAN FAKULTAS KEDOKTERAN
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (333.752 KB) | DOI: 10.21776/ub.majalahkesehatan.2017.004.04.1

Abstract

Abstrak Urtikaria merupakan lesi kulit yang terdiri dari reaksi wheal dan flare. Sebanyak 15-20% penduduk pernah mengalami urtikaria dalam kehidupannya, dan 25% diantaranya mengalami urtikaria kronik. Kejadian urtikaria lebih banyak dijumpai pada perempuan. Adanya hubungan antara proses imunologis  dan aktivitas neuroendokrin menjadi salah satu hipotesis yang mendasari patogenesis urtikaria. Ditemukannya peran DHEAS dalam fungsi imunomodulator dan antiinflamasi dapat menjadi dasar adanya peran dari terganggunya fungsi DHEAS akibat defisiensi dengan proses inflamasi pada urtikaria. Rancangan penelitian observasional potong lintang dilakukan untuk mengetahui adanya hubungan antara kadar hormon dehidroepiandrosteron sulfat (DHEAS) serum dengan aktivitas penyakit urtikaria kronis pada perempuan. Hasil uji Kruskall Wallis dengan post hoc Man Whittney menunjukkan adanya perbedaan yang bermakna antara aktivitas penyakit urtikaria dengan kadar DHEAS serum (p = 0,000). Analisis uji Spearman menunjukkan adanya korelasi negatif yang kuat antara aktivitas penyakit urtikaria dengan kadar DHEAS serum (r = -0,933; p = 0,000). Hal ini menunjukkan bahwa pada kadar yang lebih tinggi maka  hormon DHEAS dapat bersifat protektif terhadap perburukan klinis urtikaria, dan sebaliknya pada kondisi urtikaria yang kronis terjadi penurunan kadar hormon DHEAS serum. Dapat disimpulkan bahwa pada wanita, ada hubungan antara kadar DHEAS serum dengan aktivitas penyakit urtikaria kronis. Hasil ini memperkuat kemungkinan terjadinya penurunan kadar DHEAS serum yang berperan dalam patogenesis urtikaria kronis. Kata kunci: aktivitas penyakit, dehidroepiandrosteron sulfat serum, urtikaria kronis
Keabsahan Poligami: Perspektif Muhammad Abduh dan Mahmud Syaltut Rofiq, Aunur
ULUL ALBAB Jurnal Studi Islam Vol 3, No 2 (2001): Islamic Studies
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (755.023 KB) | DOI: 10.18860/ua.v3i2.6112

Abstract

Polygamy nowadays becomes a hot topic which deserves great attention. From the history, it is known that it had been practiced. Several Rasuls, Ibrahim, Ya 'kub, Daud and Sulaiman had more than one wife. When Islam came to Arab peninsula, polygamy was still in practice. Islam, then, provides the rules and limits people to only have four wives. This research is aimed at analyzing Abduh’s  and Syaltut’s concepts' of polygamy. Even though the two proposed two contrasts ideas, but, seen from its norms, the two made use of justice as the main base of applying polygamy. In this sense, only few minor technical things differentiate the two concepts.
Pengembangan Potensi Lokal untuk Bahan Baku Pangan dan Industri Sebagai Usaha Meningkatkan Ketahanan Pangan Nasional Subagio, Achmad; Rofiq, Aunur
JURNAL PANGAN Vol 18, No 2 (2009): PANGAN
Publisher : Perum BULOG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (576.242 KB) | DOI: 10.33964/jp.v18i2.202

Abstract

Dengan pertumbuhan penduduk yang tinggi, sampai saat ini kecukupan kalori dan protein masyarakat Indonesia, masih rendah. Untuk itu, diperlukan penggalian sumber protein dan karbohidat alternatif, seperti ubi kayu dan koro-koroan yang tumbuh dengan baik di lahan marginal. Tulisan ini melaporkan hasil-hasil penelitian tentang pengembangan teknologi pengolahan bahan lokal sebagai bahan baku pangan dan industri, dengan mendorong keunggulannnya dan menekan kekurangannya. Penggunaan teknologi solid state fermentation dengan bakteri asam laktat menunjukkan bahwa ubi kayu dapat diolah menjadi berbagai produk baik berupa tepung termodifikasi yang sering di sebut MOCAF (modified cassava flour), maupun pati masam. Produk-produk ini mempunyai aplikasi yang lebih luas dibandingkan produk natif-nya, seperti berbagai macam mie, kue, roti dan cokies. Selanjutnya penelitian tentang korokoroan menunjukkan bahwa beberapa macam koro-koroan mempunyai kandungan protein yang cukup tinggi (17-22%) yang didominasi oleh globulin. Namun, kandungan intinutrionalfactors dan racun pada korokoroan cukup tinggi. Saat ini telah dikembangkanbeberapa produk yang menghasilkan konsentrasi protein yang tinggi dan eliminasi sifatsifat negatif koro-koroan, seperti protein isolate, "Protein Rich Flour", lactic acid-fermented legume flour, processed beans, dan tempe koro. Demikian pula, ikan-ikan inferior dapat dijadikan sebagai sumber protein yang berkelanjutan dengan pengolahan yang tepat, sehingga mendorong ketersediaan protein yang murah. Sementara kelapa dapat dijadikan sebagai bahan pangan murah mulai dari minyak, protein dan seratnya. Berdasarkan hal tersebut, kemampuan bahan lokal berdasarkan potensi komposisinya sebagai penyedia senyawa gizi merujuknya sebagai comparative dan competitive products untuk dikembangkan guna meningkatkan ketahanan pangan nasional.
Tuberous Sclerosis Complex : A Case Report Rofiq, Aunur; Setyowati, Lita; Nugrahani, Aninda Fitri
Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol 15, No 2 (2019): December 2019
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.228 KB) | DOI: 10.22219/sm.Vol15.SMUMM2.9935

Abstract

Tuberous Sclerosis Complex (TSC) is an autosomal dominant inherited neurocutaneous disorder. Tuberous Sclerosis Complex is caused by mutations in tumor suppressor gene (TSC), both TSC1 and TSC2.  In approximately two-thirds of cases neither parent has signs of TSC and the disease is caused by a de  novo mutation. Tuberous Sclerosis Complex is classically identified by the Vort's triad in the presence of angiofibroma, mental retardation, and epilepsy. A 17-year-old woman with a major complaint of a facial bump that appeared at birth and got bigger when she reached puberty. There are white patches on the patient's body from birth. On the scalp obtained the presence of skin color plaque, while at the back and right knee obtained shagreen patch. Patientwas diagnosed with epilepsy and mental retardation by the pediatric department. No family history has the same complaints as patient. Histopathologic examination of facial bumps taken by shaving biopsy suggests the presence of hemangiomas. Based on the clinical diagnostic criteria from International Tuberous Sclerosis Complex Consensus Conference 2012, the patient meets two major criteria, macular hypopigmentation and shagreen patch so it is included in "definite diagnosis".
Diversion's Application in The Juvenile Justice System to Realize Restorative Justice Related to Deprivation of Liberty Principle Rofiq, Aunur
NORMA Vol 17, No 3 (2020): October
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/nlj.v17i3.1075

Abstract

Diversion Efforts can only be carried out in cases of Children in conflict with laws that threaten their crimes under 7 (seven) years and do not constitute a repeat of a criminal act. In contrast, the juvenile justice system requires deprivation of liberty principle and punishment related to the latest findings. This research uses the normative legal research method, using the law method, research method, and comparative method. From this research, we know that diversion in the juvenile justice system cannot be done in every child's case; it can only be done in the case of children who meet the requirements of a case protected under 7 (seven) and not a repeat of follow up. Not all cases of children go through a process of diversion. Children who have a conflict with the law are directly threatened with criminal punishment. However, there has been a reconciliation between the perpetrators and the victims, so that the deprivation of liberty principle, and criminalization, is the latest result, which is not successful. Therefore, diversion shall not be used again to protect children.Keywords: Diversion, Children, Liberty
Therapy of Schizophrenia Disorders with Spiritual Methods at the Az-Zainy Tumpang Mental Rehabilitation Boarding School Malang Regency / Terapi Gangguan Skizofrenia dengan Metode Spritual Di Pesanten Rehabilitasi Mental Az-Zainy Tumpang Kabupaten Malang Rofiq, Aunur; Anam, Khoirul; Imamudin, Mochamad
Psikoislamika: Jurnal Psikologi Islam Vol 17, No 2 (2020): Second Issue End of Year 2020
Publisher : Fakultas Psikologi Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/psikoislamika.v17i2.15523

Abstract

This study examines the psychiatric disorder Schizophrenia. The researcher took a sample of the research site at the Az-Zainy Tumpang Islamic Boarding School. In this study, it is explained that people who experience schizophrenia are very underestimated by the community and without any action for the healing process. For this reason, the Az-Zainy Islamic boarding school is one of the places for therapy for the healing process of students who have schizophrenia. With the care of KH. Zain Baik, the method of healing is by using prayer and ruqyah, namely asthma and hizb. With this research, it is hoped that it can provide insight for readers, that spiritual therapy using prayer and ruqyah methods can heal students who experience mental disorders, especially Schizophrenia. For this reason, in taking research data, researchers use descriptive-qualitative research methods with field observation research models, interviews with research objects, written data, documentation as evidence from field research. So that the four models can provide accuracy in this study. This research study resulted in an analysis that people with Schizophrenia disorder can be cured by the therapeutic process that has been carried out by KH. Zain Good. The healing process does not require a short time but also takes a long time in the healing process. Besides the therapy that has been done by KH. Zain Baik, students are also introduced to learning calistung, reciting the Koran, etc., so that students who are starting to recover can recall reading letters with their own abilities. Keyword: Therapy, Schizophrenia, Prayer, Ruqyah
Effects of 5% astaxanthin gel on angiogenesis and granulation tissue in second-degree burn animal model Rofiq, Aunur; Yuniaswan, Anggun Putri; Nugraha, Rizki Hapsari
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Burn injuries generate more free radicals and lead to complex immune dysfunction, which can delay wound healing compared to other wound types. Angiogenesis, essential for wound healing, requires granulation tissue as a marker for successful wound healing. Low concentrations of reactive oxygen species (ROS) are necessary to initiate this process. Astaxanthin is a potent antioxidant with anti-inflammatory properties, known to activate angiogenesis and modulate ROS signaling during wound healing. Methods: This experimental study aimed to evaluate 5% astaxanthin gel on second-degree burns using 30 male Wistar rats. Simple random sampling was utilized. A total of 6 groups were divided according to the time the lesions were evaluated i.e., I. Normal saline, day 2 (n=5); II. Normal saline, day 5 (n=5); III. Normal saline, day 7 (n=5); IV. 5% astaxanthin gel, day 2(n=5); V. 5% astaxanthin gel, day 5 (n=5); VI. 5% astaxanthin gel, day 7 (n=5). Histological assessment of angiogenesis and granulation tissue was based on the number of blood vessels and the extent of the wound to the dermis, respectively. Result: The mean of angiogenesis in 5% astaxanthin gel group was higher than the control group on day 5 (p-value < 0.05). The positive correlation between angiogenesis and granulation tissue was observed on day 5 (p-value < 0.05). Conclusion: The primary effect of 5% astaxanthin gel is during the proliferative phase of wound healing in second-degree burns.
Determinan wakaf tunai di kalangan milenial Setiyowati, Supami Wahyu; Slamet, Slamet; Rofiq, Aunur
Jurnal Ekonomi Modernisasi Vol. 19 No. 3 (2023)
Publisher : Fakultas Ekonomika dan Bisnis, Universitas Kanjuruhan Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21067/jem.v19i3.9138

Abstract

The purpose of this study was to examine the effects of critical factors that influence cash waqf. This study is quantitative. The population is 2021 alumni of the Faculty of Economics and Business who are Muslim. The sampling technique was based on the criteria totaling 227 alumni. The data analysis technique used smart-PLS. The results showed that knowledge, belief, and religiosity had a positive effect on attitudes. Attitudes and subjective norms did not affect cash waqf. Behavior, intention, and awareness affected cash waqf. The implication of this study is the need for socialization of waqf among the general public. Encouragement from the family of ulama and the workplace are needed to carry out cash waqf.
Co-Authors Achmad Subagio Akhmad Fauzi Cholis, Mochammad Eko Suprayitno Ekowati, Vivin Maharani Fadhillah, Is Fahmi, Much. Maftuhul Herwinda Brahmanti Indah Yuliana Januari, Anas Tania KHOIRUL ANAM Khusnudin Khusnudin, Khusnudin M. Cholis Cholis, M. Cholis Mochamad Imamudin Moh. Ihsan Mohammad Cholis, Mohammad Nugraha, Rizki Hapsari Nugrahani, Aninda Fitri Rahman, Ahmad Taufiqur Ridan Muhtadi Setiyowati, Supami Wahyu Setyowati, Lita Slamet . Sulamsih Sri Budini, Sulamsih Sri Tantari Sugiman, Tantari Wahyuni ‎, Nanik Windy Miryana, Windy Yuniaswan, Anggun Putri