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All Journal International Journal of Public Health Science (IJPHS) Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jurnal Ilmiah Farmasi Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Farmasi Klinik Indonesia Jurnal Farmasi Sains dan Komunitas Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Farmaseutik JFIOnline JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Kefarmasian AKFARINDO Jurnal Farmagazine Journal of Holistics and Health Sciences (JHHS) Jurnal Sains dan Kesehatan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian
Woro Supadmi
Universitas Ahmad Dahlan
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Jurnal Ilmiah Farmasi

 1 
KAITAN PENGGUNAAN OBAT ANALGETIK DAN ANTI INFLAMASI NON STEROID DENGAN KEJADIAN GAGAL GINJAL KRONIK PADA PASIEN HEMODIALISIS DI RSU PKU MUHAMMADYAH YOGYAKARTA Woro Supadmi; Lukman Hakim
Jurnal Ilmiah Farmasi Vol. 9 No. 2 (2012): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol9.iss2.art2

Abstract

Gagal ginjal kronik merupakan masalah kesehatan, sosial dan ekonomi dengan peningkatan insidensi, prevalensi dan morbiditas. Penelitian ini bertujuan untuk mengetahui apakah ada kaitan dan nilai odds ratio antara penggunaan analgetik dan OAINS dengan kejadian GGK di RSU PKU Muhammadiyah Yogyakarta. Penelitian ini menggunakan rancangan case control, kelompok kasus adalah pasien gagal ginjal kronik yang melakukan hemodialisa dan kelompok kontrol adalah pasien yang melakukan rawat inap tidak terdiagnosa GGK. Data sekunder diperoleh dari rekam medik pasien, data primer diperoleh melalui wawancara mendalam dengan panduan lembar pertanyaan. Data dianalisis dengan tabel 2x2 chi-square. Hasil penelitian menunjukkan bahwa penggunaan analgetik tidak berkaitan dengan kejadian GGK (OR 0,1;p>0,05;CI 0,018-0,366). Penggunaan OAINS berkaitan dengan kejadian GGK (OR 4,4; p<0,05;CI 0,906-21,97). Penggunaan analgetik dan OAINS berkaitan dengan kejadian GGK (OR 5,1;p<0,05;CI 1,057-24,78). Lama penggunaan analgetik tidak berkaitan dengan kejadian GGK (OR 1,4;p>0,05;CI 0,307-5,94), jumlah tablet penggunaan analgetik berkaitan dengan kejadian GGK (OR 23;p<0,05;CI 3,981-131). Lama penggunaan OAINS tidak berkaitan dengan kejadian GGK (OR 0,4;p>0,05;CI 0,018-7,29), jumlah tablet penggunaan OAINS berkaitan dengan kejadian GGK (OR 12;p<0,05;CI 0,936-153). Lama penggunaan analgetik dan OAINS tidak berkaitan dengan kejadian GGK (OR 0,6;p>0,05;CI 0,036-6,9), jumlah tablet penggunaan analgetik dan OAINS tidak berkaitan dengan kejadian GGK (OR 1,1;p>0,05;CI 0,138-7,934).Kata kunci : analgetik, faktor risiko, GGK (Gagal Ginjal Kronik), OAINSABSTRACTChronic renal failure is a matter of health, social and economi with increasing incidence, prevalence and morbidity. This study was aimed to observe assosiation between the used of analgesics and NSAIDs and calculate odds ratio of chronic renal failure incidence at PKU Muhammadiyah Hospital in Yogyakarta. The study used analytical observation with case control desingn,group of case cosisted as chronic renal failure patients who do hemodialysis and group of control who are not diagnosed with chronic renal failure. Secondary data were obtained from patient’s medical records, the primary data were obtained through indepth interview by guided questionnaire. Data analysis was using the 2x2 table and analyzed with chi square test to find out the correlation and the odds ratio between the use of analgesics and NSAIDs of chronic renal failure incidance. The used of analgesics not assosiation of chronic renal failure incidence (OR 0.1;p>0.05;CI 0.018 to 0,366). The used of NSAIDs assosiation of chronic renal failure incidence (OR 4.4;p< 0,05;CI 0.906 to 21.97). The used of analgesics and NSAID assosiation of chronic renal failure incidence (OR 5.1;p<0.05;CI 1.057 to 24.78). Duration of the used of analgesics not assosiation of renal failure incidence (OR 1.4;p>0.05;CI 0.307 to 5.94), the used total tablets analgesics correlation of chronic renal failure incidence (OR 23;p<0.05;CI 3.981 to 131). Duration of the used of NSAIDs was not assosiation of chronic renal failure incidence (OR 0.4;p>0.05;CI 0.018 to 7.29), number of totals tablets NSAIDs assosiation of chronic renal failure incidence (OR 12;p<0.05;CI 0.936 to 153). Duration of the used of analgesics and NSAIDs were not assosiation of chronic renal failure incidence (OR 0.6;p>0.05;CI 0.036 to 6.9), number of totals tablets to the used of analgesics and NSAIDs were not assosiation of chronic renal failure incidence (OR 1.1;p>0.05;CI 0.138 to 7.934).Keywords: analgesics, chronic renal failure, NSAIDs, risk factors
Analisis biaya pasien Severe Cutaneous Adverse Reactions (SCARs) Qarriy 'Aina Urfiyya; Musa Fitri Fatkhiya; Dyah Aryani Perwitasari; Sri Awalia Febriana; Woro Supadmi
Jurnal Ilmiah Farmasi Vol. 18 No. 2 (2022): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol18.iss2.art12

Abstract

Background: Severe Cutaneous Adverse Reactions (SCARs), including Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), and Drug Reaction with Eosinophilia and Systemic Symptom (DRESS), were the idiosyncratic reactions most commonly caused by drugs which have an impact on increasing the patient's financial burden. Objectives: This study aims to determine the highest cost component and the illness cost in patients suffering from Severe Cutaneous Adverse Reactions (SCARs). Methods: This study was an analytic observational study with a cross-sectional design. We collected direct medical costs, direct non-medical costs, and indirect costs for inpatients with SJS, TEN, and DRESS at Dr. Sardjito Yogyakarta Hospital from 2014-2018, retrospectively. Based on the societal perspective, we defined the highest cost component and the illness cost in patients with SCARs. Results: The highest cost component for SJS, and TEN patients were obtained in the health professional services (24,1% and 25,2%, respectively). Meanwhile, the highest cost component for DRESS patients was the cost of drugs (20,2%). The total illness cost of 47 SCARs patients (22 SJS patients, 6 TEN patients, and 19 DRESS patients) was IDR 666.615.321, with the highest average cost for TEN patients, followed by SJS and DRESS (IDR 16.510.595, IDR 14.205.545, and IDR 13.445.555, respectively). Conclusions: The highest cost component was the health professional services in SJS and TEN patients and the cost of medicine for DRESS patients. The management of SCARs requires considerable cost, and it is still being a financial burden on the patients.
Co-Authors . Fitriyani Adnan, Adnan Adrian A. Kaptein Adrian A. Kaptein Ajeng Diantini Akrom, Akrom Anak Agung Gede Sugianthara Andriana Sari Andriana Sari Antoni, Priski Aristia, Bella Fevi Armina Hikmawati Atikah Nur Shabrina Aulia Kurniapuri Auliya A. Suwantika Bambang Purwoko Budiyono Budiyono Cut Fatia Ulfa Cut Fatia Ulfa Damayanti, Elok Della Midi Wardhani Dyah A. Perwitasari Dyah A. Perwitasari Dyah Aryani Perwitasari Dyah Aryani Perwitasari Dyah Aryani Perwitasari Ela Fadilah Pramsa Endah Karuniawati Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Fitri Ayu Wahyuni Fitri Ayu Wahyuni Fitri Qoriawaty Fitriyani Fitriyani Fitriyani, Fitriyani Ginanjar Zukhruf Saputri Gita Husna Rahmadani Haafizah Dania Hanindia Riyani Hanita Christiandari Herjanti Ratnawiningsih Hesty Riza Oktastika Hidayah Apriliawan Hidayati, Ana Iin Ike Ardiani Ilham Bintang Agung Imaniar Noor Faridah Joko Sudibyo Joko Sudibyo Jumiati Kaptein, Adrian A. Kurniyati, . Kurniyati, . Lukman Hakim Muh Muhlis Muhammad Muhlis Muhammad MuMuhlis Muhartati, Sri Aisyah Muhlis, Muh Murwiningsih Murwiningsih Musa Fitri Fatkhiya Nur Shabrina, Atikah Perwitasari, Dyah A. Priski Antoni Qarriy 'Aina Urfiyya Rahmiati, Siti Ratna R. Restu Pranandari Rikifani, Shoma Ruri Renggani Sandra Shabran Hadiq Shoma Rikifani Siti Rahmiati Siti Rahmiati Sri Aisyah Muhartati Sri Aisyah Muhartati Sri Awalia Febriana Stefy Muliyani Muljabar Sulastri Sulastri Susilo, Rinto Tina Rostinawati Triyo Nova Wirawan Adikusuma Yulia Indah Widianti Yuptarol Mujahidah