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Journal : JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA

Optimasi Waktu Maserasi untuk Manggis (Garcinia mangostana L.) Rind Menggunakan Pelarut Etil Asetat Ni Putu Ayu Dewi Wijayanti; Dewi LPMK; Astuti KW; Fitri NPE
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 3 No. 1 (2016): Jurnal Farmasi dan Ilmu Kefarmasian Indonesia
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (72.199 KB) | DOI: 10.20473/jfiki.v3i12016.12-16

Abstract

Background: Maceration is a non-heating extraction method the result of which is affected by the type of solvent and the maceration time. Objective: To get the higher alpha-mangostin concentration (Garcinia mangostana L.) rind that was macerated using ethyl acetate solvent and to determine the optimum maceration time needed to produce high concentration of alpha-mangostin. Methods: the mangosteen rind was macerated using ethyl acetate with the variation of the maceration time of 6, 12, 24 and 48 hours. The extract was then dried using the freeze drying method. The optimum maceration time was determined by looking at the highest concentration of alpha-mangostin from each extraction time using TLC-densitometry method with a silica gel stationary phase of GF254 and a mobile phase of chloroform”methanol (10:0.1, v/v). Results: The results showed that the difference in the maceration time can affect the concentration of alpha-mangostin compound contained in the extract. Conclusions: It was found out that the 24-hour maceration time produced the highest concentration of alpha-mangostin that is 3031.34 ng.
Co-Authors Anak Agung Gede Rai Yadnya Putra Anak Agung Wahyu Putri Agustini Anak Agung Wahyu Putri Agustini Anak Agung Wahyu Putri Agustini Arifani Siswidiasari Cokorda Istri Mirayani Pemayun Cokorda Istri Mirayani Pemayun Cokorda Istri Mirayani Pemayun D. A. Satriawati Dewa Ayu Satriawati Dewi LPMK Firsta Sesarina Mintariani Firsta Sesarina Mintariani Firsta Sesarina Mintariani Fitri NPE G. M. D. Putra I Gde Pande Aninditha Putra Wicaksana I Gusti Made Aman I Gusti Ngurah Agung Dewantara Putra I Gusti Ngurah Jemmy Anton Prasetia I Made Agus Gelgel Wirasuta I Nyoman Hariyasa Sanjaya I Nyoman Hariyasa Sanjaya I Wayan Martadi Santika I Wayan Putu Sutirta Yasa I. N. K. Widjaja Ida Bagus Made Oka Komang Rima Yuniari L.P.M.K. Dewi Luh Putu Febryana L Luh Putu Febryana Larasanty Luh Putu Febryana Larasanty M. D. Abimanyu M. R Sutharini Made Diah Vendita Sakuntari Made Diah Vendita Sakuntari Made Diah Vendita Sakuntari Made Krisna Adi Jaya N. K. Cahyaningsih N. K. M. Ariani, N. L. P. V. Paramita N. P. A. D. Wijayanti N. P. A. D. Wijayanti N. W. M Lina N.M.P. Susanti Ni Komang Anik Pirgantari Ni Komang Anik Pirgantari Ni Komang Anik Pirgantari Ni Komang Cahyaningsih Ni Luh Gede Lisniawati Ni Luh Made Diah Mas Cahyani Putri Ni Luh Made Diah Mas Cahyani Putri Ni Luh Made Diah Mas Cahyani Putri Ni Luh Md Dwi Laxmi Satriani Ni Luh Md Dwi Laxmi Satriani Ni Luh Md Dwi Laxmi Satriani Ni Nyoman Fabby Sukarmini Ni Nyoman Mahatriny, Ni Nyoman Ni Nyoman Wiwik S Ni Nyoman Wiwik S. Ni Putu Ariantari Ni Putu Ayu Dewi Wijayanti Ni Putu Dhea Prameswari Awidiya Putri Ni Putu Linda Laksmiani Ni Putu Nining Gianni Ni Putu Nining Gianni Ni Putu Nining Gianni Ni Putu Sanggra Payani, Ni Putu Ni Wayan Dewi Purwanti Ni Wayan Dewi Purwanti Ni Wayan Dewi Purwanti Pande Ketut Suwanti Devi, Pande Ketut Putu Fredriktya Frisca Fariesca Putu Ita Purnama Dewi R. A. I. K. Maharani Rasmaya Niruri Rini Noviyani Sagun Chandra Yowani Santri Yulita Santri Yulita, Santri T. Maharani Yeyet C. Sumirtapura Yeyet C. Sumirtapura