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All Journal Jurnal Pendidikan Sains Pattingalloang : Jurnal Pemikiran Pendidikan dan Penelitian Kesejarahan Assets : Jurnal Ekonomi, Manajemen dan Akuntansi Jurnal Online Mahasiswa (JOM) Bidang Pertanian Jurnal Minds:Manajemen Ide dan Inspirasi Jurnal Medika Veterinaria Jurnal Ilmiah Mahasiswa Pendidikan Guru Sekolah Dasar Chimica et Natura Acta Jurnal Keperawatan Abdurrab YUME : Journal of Management JUPE : Jurnal Pendidikan Mandala Jurnal Pembangunan Nagari Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences RETORIKA : Jurnal Kajian Komunikasi dan Penyiaran Islam JKMM Iqtishaduna : Jurnal Ilmiah Mahasiswa Hukum Ekonomi Syariah Journal Peqguruang: Conference Series Riau Law Journal Hasanuddin Journal of Public Health Dharmawangsa: International Journal of the Social Sciences, Education and Humanitis JGK (Jurnal Guru Kita) e_Jurnal Ilmiah Riset Akuntansi RETORIKA : Jurnal Kajian Komunikasi dan Penyiaran Islam
Awaluddin Awaluddin
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Nursing Public Health Social Sciences Veterinary Other

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Journal : Chimica et Natura Acta

 1 
Stylotella Sp. Acetone Extract from Selayar Island and Its Activity against Breast Cancer Cells MCF-7 Awaluddin Awaluddin; Asriani Ilyas; Firnanelty Firnanelty; Aisyah Aisyah; Andi Nur Fitriani Abubakar; Aisyah Rusdin
Chimica et Natura Acta Vol 10, No 3 (2022)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v10.n3.42979

Abstract

Styletella sp. is a type of sponge in the Halichondriidae family which is rich in secondary metabolite compounds that have various bioactivities that have the potential as drugs in the future, one of which is anticancer. This study aims to determine the types of secondary metabolites found in Stylotella sp. in Selayar Island and to determine the secondary metabolite bioactivity of MCF-7 breast cancer cells. The method used is extraction using acetone, fractionation and purification. The purity test was carried out by testing three eluent systems at TLC, namely chloroform:ethyl acetate (9:1), n-hexane: acetone (8:2), chloroform: acetone (9:1) eluent. Then qualitatively and characterized by FTIR spectrophotometer. The results showed that pure isolates contained alkaloid compounds. The MCF-7 cell activity test showed an IC50 value for acetone extract of 1452.38 g/mL which has potential anticancer activity and an IC50 value for pure isolate acetone extract of 14983.52 g/mL.
Co-Authors Abd. Rasyid Syamsuri Affifudin Affifudin Ahmad Rifai Ainun Sakinah Aisyah Aisyah Aisyah Rusdin Aminah Gusri Andi Dewi Primayanti Andi Nur Fitriani Abubakar Andi Wahyuni Anita Syarifah Arifa Rizki Halim Asriani Ilyas Atjo Wahyu Belona Dadunru Salurante Budi Suhartono Bukhari Bukhari Candra Wijaya Catur Sintia Dewi Dian Sidik Arsyad Erdiansyah Rahmi Evy Maharani Firnanelty, Firnanelty H Sunardi Hamzah Hamzah Hasbullah H Ika Nurdhani Rilanti Jumriani Ansar Kiki Fitri Auliah Lalu Muhammad M. Hasan Makmur Selomo MIFTAHUL JANNAH Mislinawati Mislinawati Monawati Monawati Muhammad Assidiq Muhammad Rachmat Muhammad Rum Rahim Muhammad Yaasiin Raya Nasra Nasra Nurmasyitah Nurmasyitah Nurul Adina Putri Nurul Mawaddah Syafitri Nuzul Asmilia Reni Dayati Riamah Riamah Rini Dewi Andriani Risman Risman Said Darnius Soleman Rory Sulasning Sulasning Syarli Tiara Raihan Triva Murtina Lubis Uci Umra Yahya Thamrin