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Migraine And Pregnancy: What Should We Know Restu Susanti; Syamel Muhammad
Andalas Obstetrics And Gynecology Journal Vol 4, No 2 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.251-260.2020

Abstract

Migraine is a common headache characterized by unilateral throbbing-like headache and pulsating in nature and sometimes associated with aura. Migraine is a disabling disorder that among adults is more prevalent among women than men. It is primary headache that is often found in pregnancy. Migraine is a common disorder in women of childbearing age, and usually requires pharmacological treatment. Migraine can be considered an important risk factor for hypertensive and vascular diseases during pregnancy. Migraine therapy in pregnancy is very challenging, it must taken into a consideration about the health of the mother and fetus.  Several effective antimigraine medications are reasonably safe for use by pregnant and breastfeeding women. Prophylactic theraphy should be given to patient with recurrent migraine attacks in pregnancy. Nonpharmacological strategies are always first-line treatment options for mild migraine, and should also be used complementarily whenever pharmacological treatment is required. Women with migraine should be offered periconceptional counselling to promote a safe and healthy pregnancy. Keywords: migraine; pregnancy; therapy
The First Pelvic Exenteration in West Sumatera : A Case Report Ayu Anissa Bahri; Syamel Muhammad
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.82-88.2022

Abstract

Introduction: Pelvic exenteration (PE) is an ultra-radical surgical procedure introduced by Alexander Brunschwig in 1948, which a way for symptomatic palliative care in subjects with advanced gynecological malignancies that do not respond to radiation therapy, who experience subsequent complications including fistula, infection, or pain. Objective: The aim of this case report is to share our first experience of pelvic exenteration in patient with recurrent cervical cancer in West Sumatera. Case Report: We report the case of a 42-year-old woman, who was diagnosed with a progressive recurrent cervical cancer that had been treated with a radiotheraphy for cervical cancer stage IIIB and adjuvant chemotherapy. The patient was planned for pelvic exenteration. Prior to surgery, patient had done several preparations such as ultrasound, CT scan, laboratory tests, urologist and colorectal surgeon consult. The patient had undergone a supralevator pelvic exenteration by gynecologic oncologist, urologist and colorectal surgeon. The supralevator exenteration pelvic included total hysterectomy, bilateral salpingo-oophorectomy, cystectomy, and Miles procedure. The reconstruction process included ileal conduit and colostomy. Conclusions: Pelvic exenteration can be done with good teamwork between gynecologic oncologist, urologist, colorectal surgeon with postoperative complications (hypoalbuminemia and low intake) can be tolerated.Keywords: supralevator pelvic exenteration, cervical cancer
Menstrual Migraine : How Hormones Impact Migraine Restu Susanti; Syamel Muhammad
Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.9-17.2021

Abstract

Menstrual Migraine is divided into 2 subtypes: Menstrually Related Migraine (MRM) and Pure Menstrual Migraines (PMM). In PMM symptoms do not occur outside the menstrual cycle while MRM, symptoms can occur at other times apart from the menstrual cycle. The occurrence of menstrual migraines is related to the female hormones cycle in the form of the decrease in estrogen levels which usually occurs a week before the onset of menstruation. The mechanism is unclear, but it is thought that a decrease in estrogen levels can trigger decrease in serotonin levels, causing cranial vasodilation and sensitization of the trigeminal nerve.  Keywords: menstrual migraine, hormones
How far is Covid-19 Pandemic Situation Influence Surgical Treatment in Gynecology Cancer? : Comprehensive Review for Indonesian Syamel Muhammad; Restu Susanti
Andalas Obstetrics And Gynecology Journal Vol 4, No 2 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.203-217.2020

Abstract

Corona virus disease 2019 (COVID-19) was declared as global pandemic and caused devastating crisis in society. Despite of the growing pandemic, high quality medical services toward gynaecologic oncology patients must continue without overlooking the safety of medical staffs. Reducing risk is crucial and achieved by limiting high risk situations. The decision to perform or postpone surgery should be made based on the type and stage of the disease, medical condition of the patient, area census of COVID-19 cases, COVID-associated risks, and available logistic support including adjuvant treatment services. There are several recommendation for gynaecology cancer treatment published by several countries. However, those guidelines cannot be applied to every country across the globe because of the different situations of COVID-19 therefore we proposed guidelines for Indonesia. Surgical management for confiermed COVID-19 case should be postponed for at least 15 days for nonemergency cases. Surgery must be performed immediately for emergency cases such as Haemorrhage with unstable vital status refractory to transfusion, viscus perforation, signs of bowel obstruction refractory to conservative treatment, closed loop bowel or large bowel obstruction, hydatiform mole for live saving procedure.  Keywords: COVID-19, gynaecology cancer, surgical management
Analisis Faktor yang Berhubungan dengan Keikutsertaan Bidan Praktek dalam Pelayanan Kebidanan pada Program Badan Penyelenggara Jaminan Sosial di Kabupaten Pasaman Barat Tahun 2018 Timmy Larasati; Hafni Bachtiar; Syamel Muhammad
Jurnal Kesehatan Andalas Vol 8, No 4 (2019): Online December 2019
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v8i4.1140

Abstract

AbstrakKeikutsertaan bidan praktek pada program Badan Penyelenggara Jaminan Sosial (BPJS) masih rendah, sehingga dapat mempengaruhi angka Kematian Ibu (AKI) dan Angka Kematian Bayi (AKB), Berdasarkan studi awal pendahuluan yang dilakukan di Kabupaten Pasaman Barat, dari 87 bidan praktek hanya 30 bidan yang bekerjasama dengan BPJS (34,4%). Tujuan: Menganalisis faktor yang berhubungan dengan keikutsertaan bidan praktek dengan BPJS. Metode: Penelitian ini menggunakan metode analitik dengan pendekatan cross sectional comparative design study. Penelitian dilakukan di Bidan Praktek Kabupaten Pasaman Barat September sampai Juli 2019. Sampel penelitian adalah bidan praktek sebanyak 36 orang secara simple random sampling. Hasil: Penelitian kuantitatif menunjukkan bahwa tidak terdapat hubungan antara tingkat pengetahuan dengan keikutsertaan bidan (p=0,094), tidak terdapat hubungan antara sikap dengan keikutsertaan bidan (p=1,000), tidak terdapat hubungan antara motivasi dengan keikutsertaan bidan (p=0,077). Simpulan: Tidak terdapat hubungan yang bermakna antara tingkat pengetahuan, sikap dan motivasi dengan keikutsertaan bidan pada program BPJS dan motivasi merupakan variabel yang paling dominan dalam penelitian ini. 
Analisis Faktor-faktor yang Berhubungan dengan Kejadian Lesi Pra Kanker Serviks pada Wanita Pasangan Usia Subur di Wilayah Kerja Puskesmas Muara Bungo 1 Citra Ayu Fitrisia; Daan Khambri; Bobby Indra Utama; Syamel Muhammad
Jurnal Kesehatan Andalas Vol 8, No 4 (2019): Online December 2019
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v8i4.1147

Abstract

Lesi pra kanker serviks adalah awal perubahan menuju kanker serviks. Program pengendalian kanker serviks melalui pemeriksaan Visual Inspection with Acetic Acid (VIA) di tingkat Puskesmas dapat menurunkan insiden kanker serviks hingga 83,6%. Kanker serviks ini berkaitan dengan banyak faktor risiko.Tujuan: Menganalisis hubungan antara faktor risiko dengan kejadian lesi pra kanker serviks. Metode: Cross sectional yang dilakukan di wilayah kerja Puskesmas Muara Bungo 1 dari bulan Februari sampai Mei 2019 terhadap 362 responden. Pengambilan sampel menggunakan metode multistage random sampling. Pengambilan data menggunakan kuisioner dan observasi. Data dianalisis menggunakan uji Chi-square. Hasil: Terdapat hubungan signifikan (p<0,05) antara kejadian lesi prakanker serviks dengan usia >35 tahun, usia pertama kali berhubungan seksual <20tahun, jumlah paritas ≥4kali, menggunakan pembersih vagina dan lama penggunaan kontrasepsi hormonal ≥5 tahun. Jumlah pasangan seksual, paparan asap rokok dan riwayat keluarga kanker serviks, tidak memiliki hubungan yang signifikan dengan kejadian lesi pra kanker serviks (p≥0,05). Faktor risiko yang paling dominan adalah usia pertama kali berhubungan seksual <20 tahun (p=0,008; OR: 6,092). Simpulan: Faktor risiko usia, usia pertama kali berhubungan seksual, jumlah paritas, menggunakan pembersih vagina dan lama menggunakan kontrasepsi hormonal berhubungan dengan kejadian lesi prakanker serviks.
Hubungan gambaran spektral pulse wave doppler dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium IIB-IVA Syamel Muhammad; Dodi Suardi; Maringan DL Tobing
Majalah Kedokteran Andalas Vol 41, No 1 (2018): Published in January 2018
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (19767.526 KB) | DOI: 10.22338/mka.v41.i1.p10-21.2018

Abstract

Tujuan: Mengetahui hubungan antara gambaran spektral Doppler USG transrektal Pulse Wave Doppler dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium lokal lanjut (IIB-IVA). Metode: Menggunakan metode Prepost Design secara prospektif, dilakukan pemeriksaan Pulse wave Doppler menggunakan probe transrektal pada pasien kanker serviks stadium IIB-IVA. Pada pasien dilakukan pengukuran ukuran tumor secara ultrasonografi dan klinis sebagai ukuran awal tumor untuk menilai respon radiasi. Jumlah sampel adalah 60 untuk kelompok dengan hasil spektral Doppler baik dan buruk, yang dilakukan terapi radiasi eksternal dan dilakukan pengukuran masa kembali secara USG dan klinis untuk menentukan kriteria respon terapi. Hasil: Kelompok respon klinis buruk sebanyak 9 (75,0%) memiliki spektral vaskularisasi buruk dan sebanyak 3 (25,0%) memiliki spektral vaskularusasi baik sedangkan untuk respon klinis baik sebanyak 19(41,3%) memiliki spektral vaskularisasi buruk dan sebanyak 27 (58,7%) memiliki spektral vaskularisasi baik. Pada analisis dengan uji exact Fisher ditemukan hubungan yang bermakna (p<0,05) antara gambaran spectral PW Doppler transrektal dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium IIB-IVA dengan nilai Relative Risk (RR) 3.214 kali. Kesimpulan: Terdapat hubungan yang bermakna antara gambaran spektral Doppler dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium IIB-IVA. 
Hubungan Vaskularisasi Tumor Menggunakan Spektral Pulse Wave Doppler Dengan Respon Kemoterapi Neoadjuvant Pada Kanker Serviks Stadium IB2 Dan IIA2 Nindya Rahmadita; Syamel Muhammad; Ardian Riza
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1348.121 KB) | DOI: 10.25077/jikesi.v2i2.104

Abstract

Abstrak Kanker serviks merupakan pertumbuhan abnormal atau perubahan sel di dinding serviks, yang menduduki urutan ke 4 kanker paling umum terjadi di kalangan wanita dan urutan ke 2 kanker paling umum terjadi pada wanita usia 15 – 44 tahun di seluruh dunia. Neovaskularisasi merupakan langkah penting dalam penentuan onset dan progresifitas kanker. Kemoterapi neoadjuvant telah dievaluasi sebagai strategi pengobatan pada tahap IB2 dan IIA2. Penggunaan obat kemoterapi lebih efektif pada vaskularisasi yang berdekatan dan teratur sehingga memungkinkan aliran darah ke organ tersebut lebih cepat. Penelitian ini bertujuan untuk mengetahui hubungan vaskularisasi tumor menggunakan Spektral Pulse Wave Doppler dengan respon kemoterapi neoadjuvant pada kanker serviks stadium IB2 dan IIA2. Penelitian ini merupakan studi analitik cohort yang dilakukan pada 36 orang pasien kanker serviks stadium IB2 dan IIA2. Pengambilan sampel dilakukan dengan teknik consecutive sampling. Data meliputi hasil pemeriksaan ultrasonografi (vaskularisasi dan volume tumor). Data dianalisis meggunakan uji Chi-square. Hasil penelitian pada vaskularisasi tumor yang baik dan buruk memiliki respon baik terhadap pemberian kemoterapi neoadjuvant sebanyak 30 orang (83,3%). Tidak terdapat hubungan yang bermakna antara vaskularisasi tumor menggunakan Spektral Pulse Wave Doppler dengan respon kemoterapi neoadjuvant pada kanker serviks stadium IB2 dan IIA2. Kata kunci: vaskularisai tumor menggunakan Spektral Pulse Wave Doppler, respon kemoterapi neoajuvant, kanker serviks stadium IB2 dan IIA2.
Pemeriksaan Bercak Darah pada Kain yang Direndam & Dikubur Menggunakan Tes Teichmann Puji Anugrah; Citra Manela; Syamel Muhammad
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1210.173 KB) | DOI: 10.25077/jikesi.v2i1.299

Abstract

Background. Blood is the most important physical evidences and often found at crime scene. The Teichmann test is a confirmation test to check whether the spot really a blood.Objective. This study aims to identify the bloodstain on cloth soaked in water and buried in the ground using Teichmann test.Method. The research type is a descriptive study with a laboratory experimental study design. The sample of this study was a cloth dripped with blood, 27 samples are immersed in a bucket filled with water and 27 other samples are buried in the ground with a depth of 20 cm. The examination using the Teichmann test will be carried out on the 6th to the 14th day of exposure.Result. From the research that has been done, the results of the Teichmann test were positive on blood spots on cloth soaked in water and buried in the ground on the 6th to 9th day of exposure. Positive results indicate the formation of hemin hydrochloride crystals in the form of blackish-brown rods.Conclusion. The conclusion of this study is hemin hydrochloride crystals can still be found in blood stains on cloth soaked in water and buried in the soil using the Teichmann test but limited to the 9th day of exposure.
Hubungan Usia, Hemoglobin, dan Indeks Massa Tubuh dengan Perubahan Ukuran Tumor pada Kemoterapi Neoadjuvant Kanker Serviks Stadium IB2 dan IIA2 di RSUP Dr. M. Djamil Padang Nisa Ayu Farma; Syamel Muhammad; Asterina Asterina
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 1 (2021): Maret 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1500.886 KB) | DOI: 10.25077/jikesi.v2i1.300

Abstract

Background. On stage IB2 and IIA2 of cervical cancer standard treatment such as neoadjuvant chemotherapy is required. The changes in tumor size of this therapy is influenced by several factors, among others are Age, Hb, and BMI.Objective. To determine the relationship of Age, Hb, and BMI with changes in tumor size to neoadjuvant chemotherapy of servical cancerMethods. This of research was analytical research with using a cohort retrospective design with a total sample of 35 patients. The research instrument used was a medical record then analyzed with a with a dependent sample t-test and simple regression linier correlation test.Results. The result obtained a moderate negative power relationship between age and changes in tumor size (R= -0,412 ; P= 0,014), and there was no significant relationship between changes in tumor size with hemoglobin rate ( R= -0,107 ; P= 0,541), and BMI ( R= -0,117 ; P= 0,545).Conclusion. There is a significant relationship between age and changes in tumor size, and there is no significant relationship between hemoglobin and body mass index with changes in tumor size.