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All Journal Pharmacon Cendekia Journal of Pharmacy CERATA Jurnal Ilmu Farmasi Jurnal Pengabdian Harapan Ibu (JPHI) Madaniya Pena : Jurnal Ilmu Pengetahuan dan Teknologi Jurnal Pengabdian kepada Masyarakat JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Sasambo Journal of Pharmacy PENA ABDIMAS : Jurnal Pengabdian Masyarakat ULIL ALBAB Jurnal Pengabdian Harapan Ibu (JPHI) Jurnal Kesehatan Mahardika Benzena Pharmaceutical Scientific Journal
Kharismatul Khasanah
Program Studi Farmasi, Fakultas Farmasi, Universitas Pekalongan
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Journal : Pharmacon

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Deteksi Asam Mefenamat pada Jamu Pegel Linu yang beredar di Wilayah Pekalongan Rusmalina, Siska; Khasanah, Kharismatul; Nugroho, Denny Kurniawan
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PID IAI
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.10111

Abstract

Jamu Pegel Linu is one of the most popular herbs in Indonesia and oftenly the producers added medicinal chemicals (BKO) so that the resulting therapeutic effect is more effective. One of the BKO added is mefenamic acid. The added content of mefenamic acid can cause harmful side effects such as seizures and can even cause coma. This study aimed to detect the BKO content of mefenamic acid in Jamu Pegel Linu distributed in Pekalongan region. This research was a descriptive study with purposive sampling. The sample used was all Jamu pegel linu that were distributing in Pekalongan region that were included the inclusion and exclusion criteria. The analytical method used is Thin Layer Chromatography (TLC) with a mobile phase in the form of ethyl acetate: methanol: ammonia (80:10:10). Spotting detection was carried out under UV light at λ 254 nm. The results of the spots obtained were compared with a comparison standard. To ensure the results obtained are confirmed using the color reaction method. The results of testing of 27 samples by TLC method obtained there are 3 (three) samples of herbal medicine giving positive results indicated by the similarity of rf values with comparative standards. The results obtained were tested qualitatively with color reagents to strengthen the results.
Deteksi Asam Mefenamat pada Jamu Pegel Linu yang beredar di Wilayah Pekalongan Siska Rusmalina; Kharismatul Khasanah; Denny Kurniawan Nugroho
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PID IAI
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.10111

Abstract

Jamu Pegel Linu is one of the most popular herbs in Indonesia and oftenly the producers added medicinal chemicals (BKO) so that the resulting therapeutic effect is more effective. One of the BKO added is mefenamic acid. The added content of mefenamic acid can cause harmful side effects such as seizures and can even cause coma. This study aimed to detect the BKO content of mefenamic acid in Jamu Pegel Linu distributed in Pekalongan region. This research was a descriptive study with purposive sampling. The sample used was all Jamu pegel linu that were distributing in Pekalongan region that were included the inclusion and exclusion criteria. The analytical method used is Thin Layer Chromatography (TLC) with a mobile phase in the form of ethyl acetate: methanol: ammonia (80:10:10). Spotting detection was carried out under UV light at λ 254 nm. The results of the spots obtained were compared with a comparison standard. To ensure the results obtained are confirmed using the color reaction method. The results of testing of 27 samples by TLC method obtained there are 3 (three) samples of herbal medicine giving positive results indicated by the similarity of rf values with comparative standards. The results obtained were tested qualitatively with color reagents to strengthen the results.
Co-Authors Aji Cokro Dewanto Alfiana Nur Hidayah Ardiana Priharwanti Arum Ardianingsih Arum Ardianingsih Denny Kurniawan Nugroho Dhea Safira Eka Ari Setyorini Eka Pangestika Ekanita Desiani Elvina Yuniarti Prasetya Erma Yunita Fadilah Qonitah Hadi, Nafis Danial Hayati Soeprapto Heri Ariadi Isrofah Ivan Sulistyanto Khafid Mahbub Labibah Alawiyah Mahfur Mahfur Maruf Islammudin Meilisa, Selvia Metha Anung Anindhita, Metha Anung Mistriyani, Mistriyani Nafis Danial Hadi Nila Amanah Nor Rizka Nugroho, Denny Kurniawan Nur Shella Sya'bana Nurul Jannah Pratama, Nofran Putra Puji Wijayanti Safira Galuh Chandra Sajuri, Sajuri Sayakti, Putri Indah Selvia Meilisa SEPTI WULANDARI Siska Rusmalina Siska Rusmalina, Siska Syamsu Nur, Syamsu Triana Hertiani Vera Yunita Yuli Kurniasari Zulbayu, L.M. Andi