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JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga

JUXTA
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Published by Universitas Airlangga

ISSN : 19073623 EISSN : 26849453 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Juxta (Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga) is a scientific peer-reviewed medical doctor which relevant to a medical doctor and other health-related professions by the Faculty of Medicine Universitas Airlangga, Indonesia. Juxta provides a forum for original article to the editor and it will be published Two-times a year. Studies that focus on evaluating and understanding the complex medical importance are welcomed in Juxta.

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Articles 120 Documents

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The Relationship between Family’s Assessment Support and MDR TB Patient’s Adherence on Treatment in RSUD Dr. Soetomo Surabaya Safira Nur Ainiyah; Soedarsono Soedarsono; Pirlina Umiastuti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 2 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Multi Drug-Resistant Tuberculosis (MDR TB) is caused by Mycobacterium tuberculosis and has been resistant to isoniazid and rifampicin. Its treatment needs long time and causes some side effects which can make the patients non-adherent so that family support is needed. This study aims to know the relationship between family’s assessment support and MDR TB patient’s adherence on treatment in RSUD Dr. Soetomo Surabaya. Methods: This was an analytic observational cross-sectional study, to know the frequency distribution of family’s assessment support, MDR TB patient’s adherence, and the relationship between them in 24 MDR TB patients, recruited from MDR TB Clinic, RSUD Dr. Soetomo, Surabaya, from October 2017 to June 2018 and their family. The analysis was descriptive statistic and inferential statistic using Fisher Exact Test. Results: The results of this study showed that 83.3% of MDR TB patients’ family give high assessment support and 58.3% of MDR TB patients in RSUD Dr. Soetomo from October 2017 to June 2018 have high adherence on treatment. There is significant (p = 0.020), moderate (c = 0.468), and direct relationship between family’s assessment support and MDR TB patient’s adherence on treatment in RSUD Dr. Soetomo Surabaya. Conclusion: To improve MDR TB patient’s adherence on treatment, family must give high assessment support.

Resistance Patterns of Escherichia coli and Klebsiella pneumoniae Bacteria Against Amikacin, Ceftazidime, Meropenem, Nitrofurantoin Antibiotics in Elderly Patients with UTI in RSUD Dr. Soetomo Herdiyanti Herdiyanti; Lindawati Alimsardjono; Danti Nur Indiastuti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Urinary tract infection (UTI) is an infection that involves the urinary tract, including the urethra, bladder, ureter, and kidneys. UTI is caused by microorganisms that breed in the urinary tract which are supposed to be free of microorganisms. Two bacterias that cause UTI in general are Escherichia coli and Klebsiella pneumoniae. UTI can occur at any age but generally occurs in the elderly. UTI caused by gram-negative bacteria can be killed with several examples of antibiotics namely amikacin, ceftazidime, meropenem and nitrofurantoin. These antibiotics found resistance to the bacteria that cause the UTI. This research is to determine the resistance patterns of Escherichia coli and Klebsiella pneumoniae bacteria against amikacin, ceftazidime, meropenem, nitrofurantoin antibiotics in elderly patients with UTI in Dr. Soetomo Surabaya January-June 2017 period.Methods: A descriptive retrospective study in accordance with the logbook data of Clinical Microbiology Installation at Dr. RSUD. Soetomo Surabaya. Data from this study were taken from all populations that met the inclusion criteria. The results are presented by tables. Results: There are 163 elderly patient data which diagnosed with urinary tract infection. Escherichia coli resistance pattern against ceftazidime (75.6%), nitrofurantoin (12.6%) and meropenem (2.4%). Meanwhile, Klebsiella pneumoniae against ceftazidime (72.2%), nitrofurantoin (55.6%), meropenem (11.1%) and amikacin (2.8%). Conclusion: There were resistance number of Escherichia coli and Klebsiella pneumoniae bacteria against antibiotics amikacin, ceftazidime, meropenem, nitrofurantoin in elderly patients with UTI.

The Correlation between Family Socioeconomic Status and the Delayed Treatment of Retinoblastoma Patients at Dr. Soetomo General Hospital Surabaya Nanning Naimatuningsih; Hendrian Soebagjo; Rosy Setiawati; Rozalina Loebis
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 2 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Retinoblastoma is a cancer with the highest incidence in children and the second type of cancer that most often causes death in children in Indonesia. The level of delay in attending treatment for retinoblastoma patients in Dr. Soetomo General Hospital Surabaya is still high, because generally the patients come with an advanced stage, they are already in serious condition or with a poor prognosis. Treatment delay from the patients can be caused by the patients that are not feeling disturbed by the disease, not aware of the dangers of the disease, feel afraid, have no cost, the family does not allow them to see the doctor, and the health facilities are unaccessable. One of the factors that influence decision making whether or not someone comes to seek treatment is their socioeconomic status. The aim of this research is to analyze the correlation between family socioeconomic status with the delayed treatment for retinoblastoma patients at Dr. Soetomo General Hospital Surabaya.Methods: This research used observational analytic cross-sectional study. This research was conducted with the help of 33 retinoblastoma patients and families of retinoblastoma patients in the Outpatient Unit of the Poli Onkologi Satu Atap (POSA) Mata at Dr. Soetomo General Hospital Surabaya, and was taken by total sampling.Results: The results were obtained from 33 samples, 18.2% of patients came with a good prognosis, and 81.8% of patients came with a poor prognosis. The Fisher’s Exact Test analysis (α = 0.05) was used to determine the correlation between the father’s educational level and the delayed treatment of retinoblastoma patients (p = 0.322), correlation between the mother’s educational level and the delayed treatment of retinoblastoma patients (p = 0.129), correlation between the father’s level of occupation and the delayed treatment of retinoblastoma patients (p = 0.028), correlation between the mother’s occupational level and the delayed treatment of retinoblastoma patients (p = 0.640), correlation between the family income level and the delayed treatment of retinoblastoma patients (p = 0.026).Conclusion: There were significant correlation between father’s occupational level and family income level with the delayed treatment of retinoblastoma patients. Meanwhile there were no significant correlation between father’s educational level, mother’s educational level, and mother’s occupational level with the delayed treatment of retinoblastoma patients.

Lung Cancer Patients’ Profile in Dr Soetomo General Hospital Surabaya 2016 - 2017: Newest Report Sita Ro'yul Aini; Laksmi Wulandari; Susilowati Andajani
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Lung cancer is the leading cause of cancer death in the world, its 5 years survival rate is only 17%, whereas its incidence is the first most in men and third in women.Methods: This research was a descriptive observational study. The samples were 240 patients of lung cancer in Poly Oncology Dr. Soetomo General Hospital Surabaya 2016-2017. Sampling technique was non-random sampling (consecutive sampling). The variables were: age, sex, smoking habits, type of lung cancer, type of mutation, stage, symptoms, Vena Cava Superior syndrome, and therapy. The data analyzed were analyzed descriptively.Results: Patients mostly at age 51-55 and 56-60 years old (18% each). Ratio men and women are 1,7:1. In all type of lung cancer, men are dominant than women and mostly patients is active smoker. Ephidermal Growth Factor Receptor (EGFR) mutation found in adenosquamous (75%) and adenocarcinoma (65%). Most patients diagnosed at advance stage. Most symptoms are cough (70.4%), dyspnoea (50%), and chest pain (49.2%). Vena Cava Superior Syndrome (VCSS) found in adenocarcinoma (75%) and squamous cell carcinoma (25%). In adenocarcinoma and adenosquamous, patients commonly got targeted therapy.Conclusion: Lung cancer patients: 1) Men tend to be exposed to younger than women, 2) ratio men and women is 1.7:1 and most type in lung cancer is adenocarcinoma 3) mostly patients is active smoker, 4) EGFR mutation tent to be in women with adenocarcinoma, 5) most stage is stage IV, 6) most symptoms is cough, 7) Vena Cava Superior Syndrome is in adenocarcinoma (75%) and carcinoma cell squamous (25%), 8) patients’ therapy mostly with targeted therapy followed by chemotherapy.

APRI Profile of Cirrhotic Patients with Positive HBsAg Nadya Husni; Leonita Anniwati; Lina Lukitasari
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Hepatitis B is a viral infection that has the potency to become chronic infection and cause serious complications such as liver cirrhosis and hepatocellular carcinoma. One of the tools in diagnosing hepatitis B or cirrhosis and predicting the prognosis is aspartate aminotransferase to platelet ratio index (APRI). The purpose of this study is to evaluate the profile of APRI among cirrhotic patients with positive hepatitis B surface antigen (HBsAg).Method: This research was a descriptive observational study. The number of samples was 35 cirrhotic patients with positive HBsAg in RSUD Dr. Soetomo Surabaya from January-December 2017.Results: The majority of cirrhotic patients had >1,5 APRI score (48,57%). The most prevalent APRI score in Child A patients for first classification was 0,5 – 1,5 (5,71%) while for second classification was 0,7 – 1,5 (5,71%). The most prevalent APRI score in Child B patients for first classification was 0,5 – 1,5 (17,14%) while for second classification was 0,7 – 1,5 (11,43%). Most of Child C patients had >1,5 APRI score (22,86%). The majority of malignant degeneration patients also had >1,5 APRI score (14,29%).Conclusion: The majority of cirrhotic patients had >1,5 APRI score. In cirrhotic patients with Child A or B classification, the increase of APRI score was not as much as those with Child C or malignant degeneration classification.Keywords: Hepatitis B, cirrhosis, liver, hepatocellular carcinoma, APRI

Comparison of Increased Knowledge and Existence of Larvae between Before and After Education in Primary School Guards in Mojokerto City Anindita Abigail; Sulistiawati Sulistiawati; Erwin Astha Triyono
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Dengue fever is a tropical disease caused by Dengue virus that is still becoming one of the main health problem in Indonesia. Dengue fever patients are usually children with age ranging between 5-14 years old, that indicates a higher likelihood of infection at school compared to infection at home.The purpose of this study is to analyze the difference between knowledge and practice of DHF prevention and also the existence of larvae before and after education to the elementary school’s guard in MojokertoMethods: The research method used in this study is pre-experimental design method, which is a one group pretest and posttest study.The number of samples was 25 school guards from all elementary school in the urban villages with DHF cases in 2017.Results: The average correct answer at pretest was 58.9% while in posttest it was 80.9%. From the results of Wilcoxon test also obtained p-value 0.00 (<0.05). From observation before the education, one school was found positive with larvae, and after the education was given, all schools were found negative.Conclusion: There are differences in knowledge and practice prevention of dengue fever between before and after education in primary school guards in Mojokerto

Low Birth Weight as Risk Factor of Pneumonia Child in Primary Health Care of Surabaya Vania Ayu Puspamaniar; Retno Asih Setyoningrum; Dwi Susanti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 2 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Pneumonia is an infectious disease attacking lower respiratory tract. It has one of the highest number of world’s mortality and morbidity in children. Many risk factors are suspected as the reasons why the disease still occur a lot. One of the major risk factors is birth weight which makes their immune system immature and easier to get various complications and infections. The aim of this study is to analyze birth weight as risk factor of pneumonia in children under 5 years old. Methods: This was an analytical study with case control design. This study was held in Primary Health Care of Tambakrejo, from August to December 2017. The sample size was 22 respondents for each case and control group. Technique of sampling was total sampling. Secondary data were collected by medical records at the health center and Kartu Menuju Sehat (KMS). Data were entered into Microsoft Excel then statistically analyzed using IBM SPSS 22. The data were analyzed by Fisher’s Exact Test.Results: During August to December 2017, there were 22 respondents which were diagnosed with pneumonia in Tambakrejo Primary Health Center. Two of them (4.55%) had low birth weight and the rests had normal birth weight (95.45%). The analyze result stated that there is no significant correlation between pneumonia incidence and birth weight. Conclusion: Birth weight is one of pneumonia risk factors without significant impact.

Profile of Acyanotic Congenital Heart Defect in Children at Dr. Soetomo General Hospital Surabaya Period of January – December 2016 Katherine Fedora; I Ketut Alit Utamayasa; Sri Purwaningsih
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 2 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Acyanotic congenital heart defect is a congenital structural abnormality arising from incomplete formation of the heart or major blood vessels which generally do not interfere with the amount of oxygen or blood that reaches the body's tissues so that cyanosis are rarely found in these patients. This research aims to evaluate the profile of acyanotic congenital heart defect patients in Paediatric Cardiology Outpatient Clinic Dr. Soetomo General Hospital Surabaya period of January – December 2016 based on 4 variables; gender, age, nutritional status, type of congenital heart disease and symptoms. Until 2017, the profile of acyanotic congenital heart defect in children in Outpatient Unit of Paediatrics Department Dr. Soetomo General Hospital Surabaya has not been much researched, so this research is expected to be used as learning reference for practitioners and other readers, and also as a reference in developing management strategies for children with acyanotic congenital heart defect in the future. Methods: This was a descriptive non-experimental study using cross-sectional design and was performed by evaluating medical record of acyanotic congenital heart defect patients in Department of Paediatrics Dr. Soetomo General Hospital Surabaya period of January – December 2016 and analysed using Microsoft Excel. Results: The results of this study revealed that majority of acyanotic congenital heart defect patients were female (53.85%) with age range between 0 – <5 years old. Atrial septal defect (ASD) was the most common type of acyanotic congenital heart defect (49.8%), with sign and symptom that is commonly found in patients were failure to thrive (61.94%). Majority of patients also suffered from growth disruption with most of patients aged 0 – <5 years old are severely underweight (42.46%) and most of patients aged 5 – 18 years old are having malnutrition (38.23%).

Therapeutic Potency of Mangosteen (Garcinia mangostana) Peel Extract For Shigella dysenteriae Infected Mice’s Colon Mucosal Destruction Achmad Ilham Rizwani; Arifa Mustika; Lindawati Alimsardjono
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction : Antibiotics treatment for bacillary dysentery due to Shigella dysenteriae infection have shown resistancy. Mangosteen (Garcinia maangostana) peel have a therapy potency for Shigella dysenteriae infection due to its antibacterial and antiinflamation activity.Methods : This research was an experimental research, 30 mice was used which divided to 5 groups. The mice was infected with Shigella dysenteriae intraperitoneally, then azithromycin, aquadest, and 3 different doses of mangosteen (Garcinia mangostana) peel was given for each group for 5 days, which then the mice’s colon was collected and made into histopathology slide and its mucosal destruction was observed in 3 fields of view in each slide, 1 – 4 score was given acording to its mucosal destruction. Kruskal-Wallis test is used to analyze the data and then Mann Whitney test also used for further analysis.Result : there was a healing effect obeserved when mangosteen (Garcinia mangostana) peel extract was given to the mice’s colon mucosal, 100 mg/Kg body mass dose of mangosteen (Garcinia mangostana) peel extract already given a positive effect on mice’s mucosal colon histopathological appearance, no difference observed between 3 dose given.Conclusion : Mangosteen (Garcinia mangostana) peel extract consumption gave healing appearance to destruction of colon mucosal wall of mice with Shigella dysenteriae infection at 100 mg/Kg body mass.

Profile of Diabetes Mellitus in Benign Protate Hyperplation’s Patients with Urinary Retention in Dr. Soetomo 2016 Ahmad Zaidan Ni'am Abu Adha; Reny I'tishom; Fikri Rizaldi; Doddy Soebadi
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 2 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Introduction: Benign prostatic hyperplasia (BPH) develops inevitably related to age in almost all men starting around the age of 40 years. LUTS is the most common manifestation of BPH. There were several risk factors that play a role in the BPH and LUTS, one of which is diabetes mellitus. The incidence of diabetes mellitus is increasing throughout the world. In 2015, it was estimated that 30.3 million Americans (9.4%) and 3.4 million Canadians (9.3%) were diagnosed with diabetes. About 5% - 10% are diagnosed with type I, and around 90% - 95% are diagnosed with type II. The burden of the disease caused by diabetes is quite high and continues to increase in every country. It is estimated that the global prevalence of people with diabetes in 2013 as many as 382 million people will increase to 592 million by 2035. The exact etiology of BPH is still unknown. Acute urinary retention (AUR) is the most frequent urological emergency. This study aims to find out the number of occurrences of diabetes mellitus in BPH patients with urinary retention in Dr. Soetomo General Hospital from January to December 2016. Methods: This research used descriptive research design. Population in this study was BPH patients with acute urinary retention in Dr. Soetomo General Hospital in 2016. The total sampling method was used. The variable studied was diabetes mellitus. The data was obtained from the patient's medical record. Results: In this study, 62 subjects were found with 11 subjects with positive diabetes mellitus (17.7%) and 43 subjects with negative diabetes mellitus (69.4%). Conclusion: From the results of the study, it was found that there were 17.7% of BPH patients with acute urinary retention who had diabetes mellitus.

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Budi Santoso

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juxta@journal.unair.ac.id

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Journal Mail Official
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Kota surabaya,

Jawa timur

INDONESIA