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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Medula Berkala Kedokteran Prosiding Seminar Nasional Pakar Manuju : Malahayati Nursing Journal Jurnal Ilmu Kedokteran dan Kesehatan Acta Biochimica Indonesiana Jurnal Ilmiah Kesehatan Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Ilmu Kesehatan Indonesia (JIKSI) MAHESA : Malahayati Health Student Journal Prosiding Konferensi Nasional PKM-CSR
Evi Kurniawaty
Universitas Lampung
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Variable Effect Analysis of Household Characteristics, Family Aware of Nutrition (Kadarzi) and Environmental Sanitation as Risk Factors for Stunting Events (Comparative Study of Agricultural and Non-Agricultural Family in the Regency of South Lampung Regency, 2022) Khairunisa Berawi; Yustika Pramudyawati; Evi Kurniawaty; Samsul Bakri; Reni Zuraida
Budapest International Research and Critics Institute-Journal (BIRCI-Journal) Vol 5, No 4 (2022): Budapest International Research and Critics Institute November
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v5i4.7125

Abstract

This study aims to analyze the effect of household characteristics, Kadarzi and environmental sanitation as risk factors for stunting in a comparative study of agricultural and non-agricultural families in South Lampung district. This study uses primary data obtained from questionnaires, that are data of family characteristics, Kadarzi and environmental sanitation from 198 household samples and secondary data, that are data of stunting toddlers and agricultural and non-agricultural areas in South Lampung district in 2022. To achieve the purpose of research, the research method used is observational analytic with a cross sectional approach. The research was conducted from July 2022 to September 2022. The results showed that on the household characteristics variable, variables that had a significant effect were family occupation and family income, while variables that had no significant effect were parents’ education, nutritional knowledge, and gender of children. On the Kadarzi variable, variables that had a significant effect were the behavioral variables of Kadarzi and exclusive breastfeeding, while variables that had no significant effect were variables of weight measurement, various foods, iodized salt and nutritional supplements. On the environmental sanitation variable, the variables that have a significant effect are family latrines, sewerage and agricultural and non-agricultural zones, while variables that have no significant effect are variables of clean water sources and trash bins.
Perbedaan Waktu Penyembuhan Luka antara Pemberian Ekstrak Sel Punca Mesenkimal Tali Pusat Manusia Dengan Centella Asiatica pada Tikus Putih Jantan Nadia Gustria Dini; Evi Kurniawaty
Jurnal Ilmu Kesehatan Indonesia Vol 3, No 1 (2022): JURNAL ILMU KESEHATAN INDONESIA (JIKSI)
Publisher : Univeristas Mitra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penyembuhan luka menjadi hal yang penting. Ketika terjadi luka maka fungsi kulit tidak dapat berjalan sebagaimana seharusnya. Dilakukan berbagai usaha untuk penyembuhan luka seperti penjahitan luka, wound dressing, atau pemberian obat. Centella Asiatica dapat merangsang fibroblas agar berproliferasi dan menstimulasi sintesis kolagen. Saat ini banyak pengobatan alternatif yang dikembangkan untuk membantu proses penyembuhan luka, salah satunya metode terapi gen yang memanfaatkan sel punca. Penelitian ini bertujuan untuk mengetahui perbedaan penyembuhan luka post hecting secara makroskopis antara pemberian topikal ekstrak sel punca mesenkimal tali pusat manusia dengan Centella asiatica pada tikus putih jantan (Rattus norvegicus) galur Sprague dawley yang meliputi waktu penyembuhan luka, infeksi lokal, dan reaksi alergi. Penelitian ini menggunakan 3 kelompok perlakuan yang terdiri dari: (1) kelompok kontrol negatif (K) yang diberi Povidine iodine 1x sehari, (2) kelompok perlakuan 1 (P1) yang diberi topikal ekstrak sel punca mesenkimal tali pusat manusia 1x sehari, dan (3) kelompok perlakuan 2 (P2) yang diberi ekstrak Centella asiatica dalam bentuk salep 1x sehari dimana masing-masing kelompok terdiri dari 6 sampel. Didapatkan nilai sigma sebesar 0,049 (0,05) yang dapat disimpulkan bahwa terdapat perbedaan rerata pada kelompok kontrol dan kelompok perlakuan. Pada uji post hoc LSD, tidak didapatkan adanya perbedaan rerata pada kelompok perlakuan 1 terhadap kelompok perlakuan 2. Adanya perbedaan efektivitas antara kelompok kontrol dan kelompok perlakuanKata Kunci: Sel punca mesenkimal, Centella asiatica, skor nagaoka
Antibacterial Screening of Mangrove Extract Library Showed Potential Activity against Escherichia coli and Staphylococcus aureus Kholis Abdurachim Audah; Razethy Batubara; Julkipli Julkipli; Elza Wijaya; Evi Kurniawaty; Irmanida Batubara
Journal of Tropical Life Science Vol. 10 No. 2 (2020)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.10.02.03

Abstract

Humans are at a continuous battle against different types of diseases, so that extraordinary effort to accelerate drug discovery has become a necessity. Indonesian biodiversity is abundant natural resources that can be utilized as potential drug sources. Mangroves are among potential plant medicines that grow nearly at all Indonesian coastlines. The aim of this study was to evaluate the potential of mangrove extracts (extract library) as antibacterial agents. In this study, eight mangroves species with 16 samples from different parts of the plants such as leaf, bark or root were collected. Four types of solvents with different polarity, namely water, ethanol, ethyl acetate and hexane were used in maceration of samples producing 64 extracts. Disk diffusion method was used for antibacterial screening using five bacterial strains. There were 37 extracts showed antibacterial potential with the lowest and the highest inhibition indexes were 0.0283 and 1.8983, respectively. The highest inhibition index was recorded for ethyl acetate extract of Bruguiera gymnorrhiza root (BgR (Ea)) against Escherichia coli. The second highest inhibition index was 0.7867 recorded water extract of Avicennia marina leaf (AmL (A)) against Staphylococcus aureus. Almost all of extract showed saponin and tannin in considerable amount. This supported the data that mangrove extracts were potential as antibacterial agents.
Efek Samping Sectio Caesarea Metode ERACS (Literature Review) Arifaa Thalitha Z.; Liana Sidharti; Evi Kurniawaty
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.596

Abstract

Sectio caesarea surgery or cesarean section is a labor procedure to remove the baby through an incision in the abdomen (laparotomy) and uterus (hysterotomy). These surgeries are increasing all over the world (ACOG, 2021). The level of this operation continues to increase as evidenced by the report from the World Health Organization or WHO which will be published in 2021. The research was conducted using the literature review method. Literature review is a systematic, explicit and reproducible method for identifying, evaluating and synthesizing works. research results and ideas that have been produced by researchers and practitioners. The results of observations during the study on post-sectio caesarea (SC) birth mothers with the ERACS method, it was found that the implementation of early mobilization after 2-4 hours after surgery, most of the respondents were able to sit, and some even dared to stand. Then, after 8-10 hours, almost all of the respondents had removed the catheter, and some of the respondents had even taken a walk. After 13 hours after surgery, all respondents, based on the discussion above, which referred to several articles and journals, showed that the Caesarean section method had significant side effects, but there were also several advantages to the ERACS method, namely being able to make it easier and more effective in giving birth.
UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK RIMPANG KUNYIT Curcuma domestica TERHADAP BAKTERI Escherichia coli DAN Shigella dysenteriae Erlita Kusuma Wardani; Evi Kurniawaty; Oktadoni Saputra
Jurnal Ilmu Kedokteran dan Kesehatan Vol 10, No 2 (2023): Volume 10 Nomor 2
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v10i2.9056

Abstract

Kunyit merupakan salah satu tanaman obat keluarga atau TOGA yang sedang menjadi perhatian banyak kalangan terutama di wilayah tropis seperti di negara Indonesia. Kunyit juga telah banyak diketahui fungsinya, di bidang kesehatan kunyit juga memiliki khasiat dalam mengatasi diare atau memiliki efek antibakteri terhadap bakteri-bakteri yang dapat menyebabkan diare. Rimpang kunyit (Curcuma domestica) memiliki senyawa antibakteri yaitu terpenoid, saponin, dan tanin. Penelitian ini dilakukan untuk menguji efek antibakteri ekstrak rimpang kunyit (Curcuma domestica) terhadap bakteri Escherichia  coli dan Shigella dysenteriae. Penelitian ini dilakukan pada bulan November 2022 di Laboratorium Mikrobiologi dan Parasitologi Fakultas Kedokteran Universitas Lampung. Ekstrak rimpang kunyit Curcuma domestica  didapatkan dari Laboratorium Kimia Organik Universitas Lampung dengan teknik ekstraksi yaitu maserasi. Aktivitas antibakteri ekstrak rimpang kunyit (Curcuma domestica) dilakukan secara in vitro menggunakan metode disc diffusion pada media Mueller-Hinton Agar. Hasil penelitian ini menunjukan adanya aktivitas antibakteri ekstrak rimpang kunyit Curcuma domestica terhadap bakteri Escherichia coli dan Shigella dysenteriae dengan daya hambat kuat yaitu pada konsentrasi 50% dan 100%, namun efek antibakteri ini tidak melebihi kontrol positif. Terdapat efektivitas antibakteri ekstrak rimpang kunyit Curcuma domestica terhadap daya hambat pertumbuhan Escherichia coli dan Shigella dysenteria.
Perbandingan Efek Samping dan Kenyamanan Pasien Pasca Operasi Sectio Caesarea Metode Eracs dan Non Eracs Liana Sidharti; Arifaa Thalitha Zuleikha; Evi Kurniawaty; Ari Wahyuni
Malahayati Nursing Journal Vol 5, No 7 (2023): Volume 5 Nomor 7 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v5i7.10177

Abstract

ABSTRACT The number of sectio caesarea deliveries continues to rise. This procedure is used as a final option for various difficulties during labor. The sectio caesarea method is closely associated with anesthesia. The use of anesthesia has several side effects that can cause discomfort to patients. Currently, the Enhanced Recovery After Caesarean Surgery (ERACS) method is becoming increasingly popular as a perioperative program due to its ability to minimize side effects and reduce healing time, providing more comfort to patients. This study aims to compare the side effects and comfort of postoperative sectio caesarea patients who received either the ERACS or non-ERACS methods.This study is an observational research with a cross-sectional design. A total of 104 mothers who underwent a cesarean section at RSIA Puti Bungsu Central Lampung between November-December 2022 were involved in this study. The results showed significant differences in side effect variables such as pain (p=0.000), early mobilization level (p=0.000), and comfort (p=0.000) between the ERACS and non-ERACS methods. However, there was no significant difference in side effects such as nausea and vomiting between the ERACS and non-ERACS methods (p=0.095). The ERACS method can reduce pain, improve early mobilization, and increase comfort, but it does not reduce nausea and vomiting when compared to the non-ERACS method Keywords: Section Caesarea, ERACS, Side Effect, Comfort   ABSTRAK Persalinan sectio caesarea terus mengalami peningkatan. Tindakan ini digunakan sebagai salah satu tindakan akhir dari berbagai kesulitan persalinan. Metode sectio caesarea tidak lepas dari tindakan anestesi. Penggunaan anestesi tersebut memiliki beberapa efek samping yang bisa mengganggu kenyamanan pasien. Saat ini, metode Enhanced Recovery After Caesarian Surgey (ERACS) sebagai program perioperatif tengah populer, karena dianggap memiliki waktu penyembuhan yang lebih cepat dan meminimalisir efek samping sehingga memberikan kenyamanan kepada pasien. Penelitian ini bertujuan untuk mengetahui perbandingan efek samping dan kenyamanan pasien pasca operasi sectio caesarea metode ERACS dan Non ERACS. Penelitian ini merupakan penelitian observasional dengan desain cross sectional. Sebanyak 104 orang ibu yang melahirkan secara sectio caesarea di RSIA Puti Bungsu Lampung Tengah pada periode November-Desember 2022 terlibat dalam penelitian ini. Hasil penelitian menunjukan adanya perbedaan yang signifikan pada variabel efek samping berupa nyeri (p=0,000), level mobilisasi dini (p=0,000) dan kenyamanan (p=0,000) antara metode ERACS dan non ERACS. Tidak ditemukan adanya perbedaan yang signifikan pada efek samping berupa mual muntah antara metode ERACS dan non ERACS (p=0,095). Metode ERACS dapat mengurangi rasa nyeri, mempercepat level mobilisasi dini dan kenyamanan, namun tidak mengurangi rasa mual muntah dibandingkan dengan metode non ERACS. Kata Kunci: Sectio Caesarea, ERACS, Efek Samping, Kenyamanan
MALFORMASI BAGIAN – BAGIAN TUBUH FETUS MENCIT (Mus musculus L.) SETELAH PEMBERIAN EKSTRAK BUAH PARE (Momordica charantia L.) Silvia Andriani; Nuning Nurcahyani; Hendri Busman; Evi Kurniawaty; Iffa Afiqa Khairani
Jurnal Ilmiah Kesehatan Vol 12, No 1 (2023): Jurnal Ilmiah Kesehatan
Publisher : Universitas Muhammadiyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52657/jik.v12i1.2136

Abstract

Pare memiliki khasiat sebagai tanaman obat tradisional. Pada buah pare terdapat beberapa senyawa yang bersifat toksik yaitu senyawa momordikosida K dan L, yang diduga mempunyai sifat sitotoksik. Penelitian ini bertujuan untuk mengetahui panjang kranium, dan panjang sternum fetus mencit (Mus musculus L.) setelah pemberian ekstrak buah pare (Momordica charantia L.) terhadap mencit yang sedang hamil. Ekstrak pare diperoleh dengan cara maserasi menggunakan etanol 95%. Pemberian ekstrak buah pare (M. charantia L.) sebagai uji teratogenik pada kelainan fetus mencit. Rancangan penelitian adalah rancangan acak lengkap dengan analisis varian, yaitu menggunakan 20 ekor mencit jantan dan 20 ekor mencit betina yang dibagi dalam 4 kelompok. Setiap kelompok terdiri dari 5 ekor mencit betina yang telah hamil di beri ekstrak buah pare secara oral dimulai hari ke - 6 sampai hari 17 masa kehamilan sehari sekali pada pagi hari dengan dosis Perlakuan, aquabidest sebagai kontrol [A], [B] 22,5 mg/30 grBB , [C] 30 mg/30 grBB, dan [D] 37,5 mg/30 grBB . Selanjutnya induk mencit dibedah diambil fetusnya untuk dilakukan pengukuran terhadap panjang kranium dan panjnag sternum. Dari hasil analisis data menunjukkan bahwa secara umum pemberian perlakuan ekstrak buah pare menyebabkan penurunan rata-rata panjang kranium,dan sternum. Hasil analisis lanjut dengan BNT pada taraf 5 % menunjukkan bahwa pemberian dosis [B], [C], [D] memberikan pengaruh yang nyata terhadap penurunan panjang kranium, dan sternum. Pemberian ekstrak buah pare pada mencit hamil dosis yang paling efektif untuk menurunkan panjang kranium dan panjang sternum yaitu dosis 37,5 mg/30 grBB.
Pengaruh FKTP (Fasilitas Kesehatan Tingkat Pertama), Kesehatan Lingkungan dan Morbiditas Penyakit Berbasis Lingkungan Terhadap IPM (Indeks Pembangunan Manusia) di Provinsi Lampung dengan Metode Structural Equation Modeling (SEM) Anita Febrina; Evi Kurniawaty; Bainah Sari Dewi; Samsul Bakri; Asep Sukohar; Hari Kaskoyo
MAHESA : Malahayati Health Student Journal Vol 4, No 5 (2024): Volume 4 Nomor 5 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i5.14381

Abstract

ABSTRACT In the JKN-KIS Program, FKTP acts as a gate keeper where FKTP is responsible for providing basic health services and functioning optimally according to its competency standards. The unequal availability of health facilities and very varied geographical conditions give rise to the potential for widening inequality in health utilization. The Human Development Index (HDI) is an important indicator for measuring success in efforts to build the quality of human life (society/population), one of the elements that make up the HDI is health. Good health is supported by health facilities and good environmental health conditions so that it can reduce environmental-based morbidity rates, so that people are able to carry out productive activities. This research uses a quantitative approach with a causal design which aims to explain how the FKTP variable influences changes in mediating variables, namely environmental health and morbidity and its influence on HDI. The research was conducted in the Lampung Province area. The data source used is secondary data from BPS (Central Statistics Agency) Lampung Province and the Lampung Province Health Service for 2018-2022. The data analysis method in this research uses a path analysis model to analyze the pattern of relationships between variables. Based on the research results, there is a significant influence of FKTP on environmental health and environmental-based disease morbidity, and there is a significant influence of FKTP, environmental health and environmental-based disease morbidity on HDI in Lampung Province. Meanwhile, there is no influence of environmental health on environmental-based disease morbidity. Thus, efforts to increase the HDI in Lampung Province as a measure of community welfare can be pursued by carrying out interventions to increase FKTP, environmental health and environmental-based disease control in a representative manner, where FKTP becomes central in health efforts in the region, so that a healthy community will be able to maximum productivity to improve their welfare. Keywords: FKTP, Environmental Health, Morbidity, IPM   ABSTRAK Dalam Program Jaminan Kesehatan Nasional (yang disebut bJKN-KIS), fasilitas Kesehatan tingkat pertama (FKTP) berperan sebagai gate keeper dimana FKTP bertanggungjawab sebagai pemberi pelayanan kesehatan dasar serta berfungsi optimal sesuai standar kompetensinya. Ketidakmerataan ketersediaan fasilitas kesehatan dan kondisi geografis yang sangat bervariasi, menimbulkan potensi melebarnya ketidakadilan pemanfaatan Kesehatan. Indeks Pembangunan Manusia (IPM) merupakan indikator penting untuk mengukur keberhasilan dalam upaya membangun kualitas hidup manusia (masyarakat/penduduk), salah satu unsur yang menyusun IPM adalah kesehatan. Kesehatan yang baik didukung dengan fasilitas kesehatan dan kondisi kesehatan lingkungan yang baik sehingga mampu menekan angka kesakitan berbasis lingkungan, sehingga masyarakat mampu beraktifitas secara produktif. Penelitian ini menggunakan pendekatan kuantitatif dengan desain kausal yang bertujuan untuk menjelaskan bagaimana variable FKTP mempengaruhi atas perubahan-perubahan dalam variabel mediasi, yaitu kesehatan lingkungan dan morbiditas hingga pengaruhnya pada IPM. Penelitian dilakukan di wilayah Provinsi Lampung. Sumber data yang digunakan adalah data sekunder dari BPS (Badan Pusat Statistik) Propinsi Lampung dan Dinas Kesehatan Propinsi Lampung Tahun 2018-2022. Metode analisis data dalam penelitian ini menggunakan model path analysis (analisis jalur) digunakan untuk menganalisis pola hubungan di antara variabel. Berdasarkan hasil penelitian ada pengaruh signifikan FKTP terhadap Kesehatan lingkungan dan morbiditas penyakit berbasis lingkungan, serta ada pengaruh signifikan FKTP, Kesehatan Lingkungan dan Morbiditas Penyakit berbasis Lingkungan terhadap IPM di Propinsi Lampung. Sementara itu, tidak ada pengaruh kesehatan lingkungan terhadap morbiditas penyakit berbasis lingkungan. Dengan demikian upaya peningkatkan IPM di Provinsi Lampung sebagai tolak ukur kesejahteraan masyarakat dapat diupayakan dengan melalukan intervensi pada peningkatan FKTP, kesehatan lingkungan dan pengendalian penyakit berbasis lingkungan secara refresentatif, dimana FKTP menjadi sentral dalam upaya-upaya kesehatan di wilayahnya, sehingga masyarakat yang sehat akan mampu berproduktifitas secara maksimal untuk meningkatkan kesejahteraannya. Kata Kunci: FKTP, Kesehatan Lingkungan, Morbiditas, IPM
Co-Authors Anita Febrina Ari Wahyuni Arifaa Thalitha Z. Arifaa Thalitha Zuleikha Asep Sukohar Bainah Sari Dewi Charla Gutri Farmitali Della inike Putri Elza Wijaya Erlita Kusuma Wardani Hari Kaskoyo Hendri Busman Huzaimah Huzaimah Iffa Afiqa Khairani Irmanida Batubara Julkipli Julkipli Khairun Nisa Kholis Abdurachim Audah Kholis Abdurachim Audah Liana Sidharti Liana Sidharti Mira Kurnia Nadia Gustria Dini Natasya Hayatillah Nuning Nurcahyani Nuriah Nuriah Oktadoni Saputra Razethy Batubara Reni Zuraida S Rahmanisa Samsul Bakri Samsul Bakri Shina Megaputri Silvia Andriani Silvia Andriani Silvia Andriani Silvia Andriani Soraya Rahmanisa Soraya Rahmanisa Soraya Rahmanisa Suharyani Suharyani Syazili Mustofa T.A. Larasati Tiwuk Susantiningsih W Bahagia Winda Trijayanthi Utama, Winda Trijayanthi Yustika Pramudyawati