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Buah Naga (Hylocereus polyrhizus) Meningkatkan Kadar Hemoglobin pada Remaja Putri Thamrin, Halida; Budu, Budu; Nontji, Werna; Sharief, Suchi Avnalurini
Window of Health : Jurnal Kesehatan Vol. 1 No. 3 (Juli, 2018)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (683.231 KB)

Remaja putri memiliki risiko tinggi mengalami anemia, hal ini disebabkan hilangnya zat besi saat menstruasi.Remaja putri mempunyai risiko lebih tinggi terkena anemia dibandingkan remaja putra karena remaja putri mengalami menstruasi tiap bulannya dan keinginan untuk mengurangi makan sehingga tubuh kekurangan zat gizi penting seperti zat besi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian buah naga (Hylocereus polyrhizus) terhadap peningkatan kadar hemoglobin pada remaja putri. Penelitian ini menggunakan desain eksperimental dengan rancangan pretest-posttes with control group. Sampel dalam penelitian ini adalah mahasiswi Prodi DIII Kebidanan. Total sampel yang ditetapkan sebanyak 32 mahasiswi dibagi menjadi 2 kelompok, 16 mahasiswi yang diberikan buah naga (Hylocereus polyrhizus) sebagai kelompok intervensi dan 16 mahasiswi yang diberikan edukasi nutrisi sebagai kelompok kontrol. Pengukuran kadar hemoglobin dilakukan sebelum dan setelah pemberian perlakuan selama 8 minggu, pengukuran periodik dilakukan tiap 2 minggu. Analisa data menggunakan Uji Paired t-test. Hasil penelitian menunjukkan ada pengaruh namun tidak ada perbedaan bermakna pemberian buah naga (Hylocereus polyrhizus) terhadap peningkatan kadar hemoglobin pada remaja putri (P>0,05).

STATUS ANTIOKSIDAN GLUTATION PADA PASIEN TUBERKULOSIS PARU DI BALAI KESEHATAN PARU (BKPM) MAKASSAR Yuniastuti, Ari; Yusuf, Irawan; Massi, Muh Nasrum; -, Budu
Biosaintifika: Journal of Biology & Biology Education Vol 5, No 2 (2013): September 2013
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v5i2.2745

AbstrakAntioksidan merupakan senyawa untuk pertahanan tubuh host terhadap radikal bebas. Pada pasien tuberkulosis paru (TB paru), rendahnya antioksidan menyebabkan kerusakan jaringan. Salah satu antioksidan tubuh adalah glutation. Rendahnya glutation berhubungan dengan gangguan sistem imun, sehingga menyebabkan keparahan penyakit pada pasien TB paru. Penelitian ini bertujuan mengetahui kadar glutation plasma penderita tuberkulosis paru. Desain penelitian ini adalah kohort prospektif. Sampel TB paru dipilih di Balai Besar Kesehatan Paru Masyarakat (BBKPM), Makassar yang sesuai dengan kriteria inklusi dan eksklusi dan sesuai kadatangan (consecutive sampling). Dua mililiter darah diambil dari setiap sampel, kemudian dilakukan pemeriksaan kadar glutation dengan ELISA. Hasil penelitian menunjukkan bahwa kadar glutation sampel pasien TB paru sebelum pemberian obat antituberkulosis (OAT) sebesar 0,483830,0344 mM dan setelah pemberian OAT sebesar 0,494650,0371 mM. Setelah pemberian OAT kadar glutation mengalami peningkatan sebesar 2,2% meskipun masih lebih rendah dari kadar glutation normal.AbstractAntioxidants prevent hosts against free radicals. In pulmonary tuberculosis (TB) patients, the low level of antioxidants may cause tissue damage in oxidative hosts. One of antioxidants is glutathione. The poor glutathione level correlates with immune system disorder. The current study aimed to determine glutathione plasma levels in pulmonary tuberculosis patients. The study design was prospective cohort. Pulmonary TB samples were obtained from patients in the Lung Health Centre (BBKPM) in Makassar, and they were selected based on the inclusive and exclusive criteria and on their admittance times (a consecutive sampling technique). Two mililiters of blood was taken from each sample and the glutathione level was examined using ELISA. The study indicated that the glutathione level of the pulmonary TB patients before administered with antitubeculosis drug was 0.483830.0344 mM and after antituberculosis drug was 0.494650.0371 mM. After administration of antituberculosis drug the glutathione level increased by 2.2%, although still lower than normal glutathione level.

Buah Naga (Hylocereus polyrhizus) Meningkatkan Kadar Hemoglobin pada Remaja Putri Thamrin, Halida; Budu, Budu; Nontji, Werna; Sharief, Suchi Avnalurini
Window of Health : Jurnal Kesehatan Vol. 1 No. 3 (Juli, 2018)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Young women have a high risk of anemia, this is due to iron loss during menstruation. Female teenagers have an increased risk of anemia compared to young men because young women experience menstruation every month and the desire to reduce food so that the body lacks important nutrients such as iron. This study aims to determine the effect of dragon fruit (Hylocereus polyrhizus) on increasing hemoglobin levels in young women. This study used an experimental design with pretest-posttes with control group design. The sample in this research is student Prodi DIII Kebidanan. The total sample of 32 female students was divided into 2 groups, 16 female students were given dragon fruit (Hylocereus polyrhizus) as intervention group and 16 female students who were given nutrition education as control group. Measurements of hemoglobin levels were performed before and after treatment for 8 weeks, periodic measurements were performed every 2 weeks. Data analysis using Paired t-test. The results showed no effect but no significant difference of dragon fruit (Hylocereus polyrhizus) to increase hemoglobin level in female adolescent (P> 0,05).

HUBUNGAN HASIL SUPPLEMENTARY SCALES MMPI-2 TERHADAP HASIL UJI KOMPETENSI PADA ALUMNI KEBIDANAN MAKASSAR PERIODE MARET TAHUN 2018 Yuliati Yuliati; Saidah Syamsuddin; Budu Budu
Jurnal JKFT Vol 5, No 1 (2020): Jurnal JKFT
Publisher : Universitas Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31000/jkft.v1i1.2853

Various government efforts to reduce Maternal Mortality Rate (MMR), Infant Mortality Rate (IMR), and Under-Five Mortality Rate (UFMR) have been carried out through the Maternal and Child Health program. The research aimed to investigate the relationship between MMPI-2 Supplementary Scales Result and Competency Test Result on Makassar Midwifery Alumni in the Period of March 2018.The research used the observational descriptive method with the cross sectional study design. The research population was all midwifery alumni Health Higher School Mega Rezky Makassar and Midwifery Academy Yapma who attended the competency test in the period of March 2018. Samples were selected using the consecutive sampling technique. The samples were as many as 122 respondents who were divided into two groups namely 61 competent and 61 incompetent respondents. Data were collected MMPI-2 test questionnaire distributed to the respondents and examined by experts. The data analysis used the Chi-square test.The research result of the Supplementary scales distribution indicates the significant scales namely : the Anxiety (A),Ego Strength (ES), Responsibility (Re), Post Traumatic Disorder Keane (PK), and Addiction Admission Scale (AAS). This proves that there is the relationship between MMPI-2 Supplementary Scales Result and competency test result. Key words : Supplementary Scales, Midwifery Alumni, Competency Test.

Risk Assessment in Hereditary Colorectal Cancer Family by Using APC and MSH2 mRNA Gene Expression and Bayesian Analysis Tjahjadi Robert Tedjasaputra; Mochammad Hatta; Muhammad Nasrum Massi; Rosdiana Natzir; Ilhamjaya Patellongi; Marcellus Simadibrata; Ibrahim Labeda; Rina Masadah; Muhammad Luthfi Parewangi; Prihantono Prihantono; Andi Asadul Islam; Agussalim Bukhari; Budu Budu; Rinda Nariswati
The Indonesian Biomedical Journal Vol 12, No 4 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i4.1329

BACKGROUND: Some of colorectal cancers (CRCs) are familial, however, heterozygote relatives have approximately 80% lifetime risk of cancer. Risk assessment of CRC’s family could be calculated by direct measurement of mRNA gene expression and Bayesian theorem which is modifying initial background of pedigree risk with additional conditional information. This application has not been reported.METHODS: The cross-sectional translational sequential studies were performed: (1) adenomatous polyposis coli (APC) and MutS homolog (MSH)2 mRNA quantitative RT PCR gene expressions in tissue and whole blood CRC patients; (2) gene expression was determined in matched controls; and (3) pedigree and Bayesian analysis was calculated in the patient’s family of Proband.RESULTS: Fourty CRC and 31 control subjects were enrolled. The mean blood APC level control’s group was 13,261±670 fold-change (fc) and blood MSH2 level was 12,219±756 fc. The cut-off points for hereditary APC was 12,195 fc and MSH2 was 11,059 fc. The mean APC blood level in CRC subject was 11,578±2,638 fc and MSH2 blood level was 11,411±2,912 fc. There were significant differences APC and MSH level between tissue and blood level in CRC. Eight of 40 CRC subjects had a history of familial CRC. Four patients and 10 Probands were available for recurrence risk evaluation of pedigree analysis, RNA PCR quantitative and Bayesian calculation.CONCLUSION: There was determined a cut-off point of hereditary mRNA quantitative expression. The APC and MSH2 levels in CRC subjects were significantly lower than controls. Bayesian analysis allowed for the calculation of relative risk in CRC family members and considered in clinical practice.KEYWORDS: hereditary CRC, APC gene, MSH gene, Bayesian analysis

Application of Evaluation and Feedback Methods to the Achievement of Lactation Massage Skills of Midwifery DIII Students Heriyana, Desi; Budu, Budu; Nontji, Werna; Sutrisno, Sutrisno; Ahmad, Mardiana; Usman, Andi Nilawati
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

This study aims to analyze the effect of the application of evaluation and feedback methods on the achievement of knowledge and skills of lactation massage in the intervention group and control group. This study used Quasi experimental design with pretest-posttest control group design. The sampling technique was quota sampling with a total of 44 second semester DIII midwifery students divided into two institutions, namely 22 students from Batari Toja Watampone Midwifery Academy as the intervention group and 22 students from Lapatau Midwifery Academy as the control group. The study was conducted during February-April 2023. Data were analyzed using Wilcoxon, Mann-witney, Chi-Squard and Kruskal wallis tests. The results of the study in the intervention group on knowledge achievement showed that 81.8% were lacking, 18.2% were sufficient and after the posttest assessment as many as 36.4% were sufficient and 63.3% were good with a value of P = 0.000, while for skill achievement in the pretest assessment 90.9% were sufficient, 9.1% were good then there was a change in the posttest assessment to 13.6% good and 86.4% very good with a value of p = 0.000. While the control group for knowledge achievement was 95.5% insufficient and 4.5% sufficient in the pretest and posttest assessments showing 54.5% insufficient, 27.3% sufficient and 18.2% good with a value of P = 0.008. Then for skill achievement as much as 100% was sufficient in the pretest assessment and increased to 40.9% good, 59.1% very good after the posttest with a value of P = 0.000. Based on the results obtained, it can be stated that the application of the evaluation and feedback method has a better effect on the learning outcomes of lactation massage.Abstrak: Penelitian ini bertujuan untuk menganalisis pengaruh penerapan metode evaluasi dan feedback terhadap capaian pengetahuan dan keterampilan pijat laktasi pada kelompok intervensi dan kelompok kontrol. Penelitian ini menggunakan desain Quasi eksperimen dengan rancangan pretest-posttest control group design. Teknik pengambilan sampel adalah quota sampling dengan jumlah 44 mahasiswa DIII kebidanan semester II yang terbagi atas dua institusi yaitu 22 mahasiswa dari Akademi kebidanan Batari Toja Watampone sebagai kelompok intervensi dan 22 mahasiswa Akademi Kebidanan Lapatau sebagai kelompok kontrol. Penelitian dilaksanakan selama bulan februari- April 2023. Data dianalisis menggunakan uji Wilcoxon, Mann-witney, Chi-Squard dan kruskal wallis. Hasil penelitian pada kelompok intervensi terhadap capaian pengetahuan menunjukkan sebanyak 81,8% kurang, 18,2% cukup dan setelah penilaian posttest sebanyak 36,4% cukup dan 63,3% baik dengan nilai P=0,000, sedangkan untuk capaian keterampilan pada penialian pretest 90,9% cukup, 9,1% baik kemudian terjadi perubahan pada penilaian posttest menjadi 13,6% baik dan 86,4% sangat baik dengan nilai p=0,000. Sementara kelompok kontrol untuk capaian pengetahuan sebanyak 95,5% kurang dan 4,5% cukup pada penilaian pretest dan posttest menunjukkan 54,5% kurang, 27,3% cukup dan 18,2% baik dengan nilai P=0,008. Kemudian untuk capaian keterampilan sebanyak 100% cukup pada penilaian pretest dan meningkat menjadi 40,9% baik, 59,1% sangat baik setelah posttest dengan nilai P=0,000. Berdasarkan hasil yang diperoleh dapat dinyatakan bahwa penerapan metode evaluasi dan feedback memiliki pengaruh yang lebih baik dalam capaian pembelajaran pijat laktasi.

STATUS ANTIOKSIDAN GLUTATION PADA PASIEN TUBERKULOSIS PARU DI BALAI KESEHATAN PARU (BKPM) MAKASSAR Ari Yuniastuti; Irawan Yusuf; Muh Nasrum Massi; Budu -
Biosaintifika: Journal of Biology & Biology Education Vol 5, No 2 (2013): September 2013
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v5i2.2745

AbstrakAntioksidan merupakan senyawa untuk pertahanan tubuh host terhadap radikal bebas. Pada pasien tuberkulosis paru (TB paru), rendahnya antioksidan menyebabkan kerusakan jaringan. Salah satu antioksidan tubuh adalah glutation. Rendahnya glutation berhubungan dengan gangguan sistem imun, sehingga menyebabkan keparahan penyakit pada pasien TB paru. Penelitian ini bertujuan mengetahui kadar glutation plasma penderita tuberkulosis paru. Desain penelitian ini adalah kohort prospektif. Sampel TB paru dipilih di Balai Besar Kesehatan Paru Masyarakat (BBKPM), Makassar yang sesuai dengan kriteria inklusi dan eksklusi dan sesuai kadatangan (consecutive sampling). Dua mililiter darah diambil dari setiap sampel, kemudian dilakukan pemeriksaan kadar glutation dengan ELISA. Hasil penelitian menunjukkan bahwa kadar glutation sampel pasien TB paru sebelum pemberian obat antituberkulosis (OAT) sebesar 0,48383±0,0344 mM dan setelah pemberian OAT sebesar 0,49465±0,0371 mM. Setelah pemberian OAT kadar glutation mengalami peningkatan sebesar 2,2% meskipun masih lebih rendah dari kadar glutation normal. AbstractAntioxidants prevent hosts against free radicals. In pulmonary tuberculosis (TB) patients, the low level of antioxidants may cause tissue damage in oxidative hosts. One of antioxidants is glutathione. The poor glutathione level correlates with immune system disorder. The current study aimed to determine glutathione plasma levels in pulmonary tuberculosis patients. The study design was prospective cohort. Pulmonary TB samples were obtained from patients in the Lung Health Centre (BBKPM) in Makassar, and they were selected based on the inclusive and exclusive criteria and on their admittance times (a consecutive sampling technique). Two mililiters of blood was taken from each sample and the glutathione level was examined using ELISA. The study indicated that the glutathione level of the pulmonary TB patients before administered with antitubeculosis drug was 0.48383±0.0344 mM and after antituberculosis drug was 0.49465±0.0371 mM. After administration of antituberculosis drug the glutathione level increased by 2.2%, although still lower than normal glutathione level.

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