Article Per Year (5 Year)
p-Index From 2019 - 2024
1.503
P-Index
This Author published in this journals
All Journal VALENSI BIOTIK: Jurnal Ilmiah Biologi Teknologi dan Kependidikan KOVALEN: Jurnal Riset Kimia Jurnal Pendidikan Kimia (JPKim) Indonesian Journal of Pure and Applied Chemistry Jambura Journal of Chemistry
Boima Ramses Situmeang
Departmen Of Chemistry, Sekolah Tinggi Analis Kimia Cilegon, Banten, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : VALENSI

 1 
Isolasi Senyawa Triterpenoid dari Ekstrak Etil Asetat Pirdot (Saurauia vulcani. Kurth) Boima Ramses Situmeang; Achmad Rante Suparman; Murtihapsari kadarusman; Apriani sulu parumbak; Tati Herlina
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 4, No. 2, November 2018
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (21.168 KB) | DOI: 10.15408/jkv.v4i2.7272

Abstract

Pirdot plant(Saurauia vulcani. Kurth)is a plant that grows naturally in a tropical climate. During this decoction pirdot leaves plants are used by the people to treat diabetes disease. The purpose of this study was to isolate triterpenoid compound from ethyl acetate extract of pirdot leaves. The sample extraction was performed by total of maceration method using ethyl acetate as a solvent. The separation and purification of the compound was carried out by column chromatography method followed by stain pattern analysis with thin layer chromatography (TLC). Structure characterization of pure compound was determined using UV, IR, 1H-NMR, 13C-NMR, DEPT 135º, HMQC, HMBC, 1H-1H COSY and MS spectroscopies including compared with various literatures. Based on the analysis result, the pure isolate obtained was identified as a pentacyclic triterpenoid compound, 3-hydroxy acid, 12(13)-en,28-oleanolate acid with the molecular formula C30H48O3. The triterpenoid compound of pentacyclic oleanolic acid is the first reported from the pirdot plant (Saurauia vulcani. Kurth). 
Antibacterial Diterpenoid Against Pathogenic Oral Bacteria of Streptococcus Mutans ATCC 25175 Isolated From Sarang Semut (Myrmecodia Pendans) Mieke H Satari; Boima Situmeang; Indah Permata Yudha; Dikdik Kurnia
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 5, No. 2, November 2019
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (61.465 KB) | DOI: 10.15408/jkv.v5i2.8864

Abstract

Discovery of new antibacterial agent to treat oral disease caused by pathogenic oral bacteria is an attracted focus to more pay attention of researcher. The tropical natural product is the promising sources of new bioactive as antibacterial compounds. The epiphyte plant of Sarang Semut (M. pendans) empirically has been used as a drug to treat various diseases. Our previous research found that ethyl acetate extract of Sarang Semut inhibited the bacteria growth of Enterococcus faecalis. This study aims to isolate, structure determination and antibacterial activity evaluation of active compound against Streptococcus mutans ATCC 25175. The isolation by combination chromatography on normal and reverse phase resulted an antibacterial compound 1. Based on the analysis of the spectroscopic data including IR, FTIR, 1H-NMR, 13C-NMR, 2D-NMR as well as by mass spectroscopic (MS) and compare to reported data, structure of compound 1 was suggested as terpenoid type diterpene derivative. Antibacterial activity evaluation by Kirby-Bauer method of compound 1 against S. mutans ATCC 25175 showed inhibition zone values were 17.8, 14.5 and 11.1 mm at 10000, 5000 and 1000 ppm, respectively, while the MIC and MBC values were 18.125 ppm with MBC of 2500 ppm, respectively.
Co-Authors Achmad Rante Suparman, Achmad Rante Afif Hidayatul Mustafid Afif Hidayatul Mustafid Ahmad Rifa’i Apriani Sulu Parubak Apriani sulu parumbak Ari Widiantoro Dian Susvira Dikdik Kurnia Fauzan Amin Firman Rezaldi Hafidz Al Asad Holisha Widiyanto Ibrahim, Agus Malik Ika Agustia Umami Indah Permata Yudha Isna Lailatusholihah Micha Mahardika Mieke H Satari Moh Adam Mustapa Muhammad Mutfi Amin Shidqi Murtihapsari, Murtihapsari Nurhayati Bialangi Radite Yogaswara Rohmatulloh Saronom Silaban Siti Rohmiyati Sri Agustina Sriwijayanti Susparini, Ninik Triayu Tati Herlina Tati Herlina Weny Nuraeni Yasmiwar Susilawati Yeyen Maryani Yuszda K. Salimi