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Journal : Care : Jurnal Ilmiah Ilmu Kesehatan

IDENTIFIKASI SENYAWA GARLISIN DAN KUERSETIN SEBAGAI SENYAWA ANTIMIKROBA PADA SEDIAAN BASAH DAN KERING BAWANG PUTIH (Allium sativum L.) Fanny Thresia Yunus; Ari Suwondo; Martini Martini
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 8, No 2 (2020)
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.09 KB) | DOI: 10.33366/jc.v8i2.1693

Abstract

Indonesian people have long used garlic as traditional medicine because it contains various chemical compounds that are beneficial to the body. In this study identification of garlicin and kuersetin compounds in garlic as an antibacterial. This study requires 500 grams of garlic each in wet preparations consist of fine garlic and garlic extract, and dry preparation consists of garlic powder. In addition, this research requires 2,1 liters of 96% ethanol. Garlic is dried at 400C with TMI Vacuum Oven and extracted at 250C. Garlic powder is made using Krisbow dry cabinet with a temperature of 1000F and a pressure of 10 Pa. Garlisin content was identified by GCMS Shimadzu TQ8030 and FTIR Perkin Elmer Spectrum Two UATR, while identification of quercetin using Shimadzu HPLC type UFLC. The result shows that the compound garlicin (C6H10S2) was found in the three samples with identical similarity levels. In addition, the three samples showed differences in kuersetin content. The highest kuersetin content was 458.729 ppm garlic extract while the lowest kuersetin content was 81.181 ppm fresh garlic. Both of these compounds have potential as antimicrobial compounds.
FAKTOR YANG MEMPENGARUHI KLB CAMPAK ANAK USIA SEKOLAH DASAR Ferry Ardhiansyah; Kamilah Budhi R; Ari Suwondo
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 8, No 1 (2020)
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.788 KB) | DOI: 10.33366/jc.v8i1.1202

Abstract

Measles is a very contagious disease and still a health problem in Indonesia. Immunization coverage of measles BIAS in Pesawaran District is quite good (98.8%), but the incidence measles outbreaks in elementary school-age children still occur, this can be caused by various child factors, maternal and environmental factors. The purpose to examine the factors that influence outbreaks of measles are children of primary school age. The observational analytics study design with a mix methods approach. The participants consist of 27 cases and 54 controls, in-depth interviews with UKS teachers. Dependent variable was measles outbreak incidence in primary school age, independent variables were contact history, maternal age, maternal education, occupancy density, and UKS teacher knowledge. Bivariate using Chi Square test and multivariate analysis using logistic regression test. The result of bivariate analysis showed that there was a correlation between contact history (p=0,001), maternal age (p=0,009), occupancy density (p=0,023) with the incidence of measles outbreaks of primary school age children. Logistic regression test showed the significance value of contact history (p= 0,024), occupancy density (p=0,036), The result of in-depth interviews UKS teacher knowledge about measles is good. Conclusion of the factors that influence the incidence of measles outbreaks of primary school age children is a history of contact and occupany density with probability 83,25%. This research needs to be continued by examining other risk factors such as nutritional status, areas prone to outbreaks and implementation of the Clean and Healthy Behavior Program (PHBS) in schools.