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All Journal Natural Science: Journal of Science and Technology LINK Biocelebes The Indonesian Journal of Public Health Pharmascience Berkala Kedokteran JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Acta Pharmaciae Indonesia : Acta Pharm Indo Majalah Farmaseutik Jurnal Farmasi Higea Jurnal Kefarmasian AKFARINDO PREPOTIF : Jurnal Kesehatan Masyarakat Journal of Health Community Service Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)

Muhamad Rinaldhi Tandah

Department Of Pharmacy, Faculty Of Mathematics And Natural Sciences, Tadulako University, Indonesia

Author-ID : 542568

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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FORMULASI GEL EKSTRAK PATIKAN KEBO (Euphorbia hirta L.) DAN UJI AKTIVITAS TERHADAP BAKTERI Staphylococcus epidermidis Tri Novrianti Djanggola; Yusriadi Yusriadi; Muhamad Rinaldhi Tandah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 2 No. 2 (2016): (October 2016)
Publisher : Universitas Tadulako

Patikan kebo (Euphorbia hirta L.) is a plant that have activity of inhibiting the Staphylococcus epidermidis bacteria, which was known as the cause of acnes. Flavonoids and tannin as antibacterial compounds which supposedly can act as an active antiacne. Purposes of this research is formulating extract gel of patikan kebo and antibacterial activity against Staphylococcus epidermidis by agar difussion method using paper disc and to know stability of the gel. The result was analyzed by One Way ANOVA with confidence level of 95%, followed by Duncan test. The result of this research showed test antibacterial activity that difference among the concentration extract has a noticeable difference zone of inhibition and extract gel of patikan kebo not have good physical quality during 28 days of storage. Keywords: Patikan kebo (Euphorbia hirta L.), gel, antibacterial, Staphylococcus epidermidis

PROFIL KANDUNGAN KIMIA DAN AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN BAMBAN (Donax canniformis (G. Forst.) K. Schum.) TERHADAP Staphylococcus aureus Hidayatullah Hidayatullah; Syariful Anam; Muhamad Rinaldhi Tandah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 1 No. 2 (2015): (October 2015)
Publisher : Universitas Tadulako

Bamban (Donax canniformis (G. Forst.) K. Schum.) is one of the family Marantaceae plant that has many uses such as traditional medicine. Methanol extract of bamban leaves contains phenolic, tannins and saponins compounds. The purpose of this research is to determine the class of compounds that has antibacterial activity against Staphylococcus aureus and determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methanol extract of bamban leaves. This extract was prepared using maceration method with methanol solvent. Determination the class of compounds was initiated by bioautografi test in order to determine spots which has have antibacterial activity. Subsequently, the spot were identified the class of compound using reagent spray FeCl3 and H2SO4 10%. The determination of MIC and MBC using dilution method. Research showed there are three compounds that had antibacterial activity. These compounds were predicted as spot I and spot II which were phenolic compounds and spot III as a saponin compound. MIC and MBC value of the methanol extract of leaves bamban leaves 8% and 13%, respectively.

Formulasi Sediaan Mouthwash Pencegah Plak Gigi Ekstrak Biji Kakao (Theobroma cacao L) Dan Uji Efektivitas Pada Bakteri Streptococcus mutans: Mouthwash Formulation of Tooth Plaque Preventing of Kakao (Theobroma cacao L) Seed Extract and Effectivity Test on Streptococcus mutans Apriyanti Anastasia; Yuliet Yuliet; Muhamad Rinaldhi Tandah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 3 No. 1 (2017): (March 2017)
Publisher : Universitas Tadulako

Research on the formulation of preparations mouthwash prevention of dental plaque extract of cocoa beans also has been tested in Streptococcus mutans bacteria by variations in the concentration of glycerin as a humectant in preparation which aims to determine the effect of different concentrations of glycerin as a humectant to the physical properties, chemical properties and inhibition zone Streptococcus mutans bacteria in mouthwash formula and to know the mouthwash formula that has the physical quality and the highest antibacterial activity. The method used includes the step of extraction of cocoa beans, preparation of a mouthwash with 4 formula using variations of glycerin F1 (0%), F2 (15%), F3 (20%) and F4 (25%) followed by an evaluation formula that includes organoleptic tests, pH test and the test of inhibition diameter. Tests performed on days 0, 7, 14 and 21. The results showed the concentration of glycerin as a humectant in a mouthwash formula cocoa seed extract has an effect on the diameter of inhibition zone, but did not have a significant effect on the physical and chemical properties of cocoa seed extracts mouthwash, The concentration of glycerin which meets the physical quality and the most excellent antibacterial activity that is 15% contained in the formula 2.

Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Daun Sereh (Cymbopogon nardus L. Rendle) terhadap Bakteri Staphylococcus aureus Penyebab Jerawat: Anti Bacterial Activity Test Of Extract Gel Formulation Of Lemongrass Leaves (Cymbopogon nardus L. Rendle) on Staphylococcus aureus Acne Causing Bacteria Sarlina Sarlina; Abdul Rahman Razak; Muhamad Rinaldhi Tandah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 3 No. 2 (2017): (October 2017)
Publisher : Universitas Tadulako

Penelitian tentang uji aktivitas antibakteri sediaan gel ekstrak daun sereh (Cymbopogon nardus L.Rendle) terhadap pertumbuhan bakteri Staphylococcus aureus telah dilakukan. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi karbopol, konsentrasi ekstrak, dan kombinasi keduanya terhadap stabilitas gel dan aktivitas antibakteri terhadap Staphylococcus aureus. Ekstrak daun sereh (Cymbopogon nardus L.Rendle) diperoleh dengan cara maserasi dengan etanol 96%. Desain penelitian menggunakan analisis data ANOVA rancangan acak lengkap pola faktorial dengan variasi konsentrasi ekstrak 5%, 10%, 15%, 20% dan karbopol sebagai basis gel dengan konsentrasi 0,5%, 1% dan 2%. Evaluasi stabilitas sediaan mencakup uji organoleptis, uji homogenitas, uji pH, uji viskositas, dan uji aktivitas antibakteri. Hasil penelitian menunjukkan bahwa variasi konsentrasi ekstrak mempengaruhi stabilitas dan aktivitas antibakteri gel ekstrak daun sereh (Cymbopogon nardus L.Rendle). Variasi konsentrasi karbopol mempengaruhi aktivitas antibakteri tetapi tidak mempengaruhi stabilitas. Kombinasi variasi konsentrasi karbopol dan ekstrak mempengaruhi aktivitas antibakteri. Kombinasi perlakuan yang baik diperoleh pada formula A2B4, karena memiliki aktivitas antibakteri tertinggi yaitu 14,56 mm.

ANALISIS EFEKTIVITAS BIAYA PENGGUNAAN ANTIBIOTIK SIPROFLOKSASIN DAN SEFTRIAKSON PADA PASIEN INFEKSI SALURAN KEMIH RAWAT INAP DI RSU ANUTAPURA PALU TAHUN 2016-2017 Siti Atika; Ihwan Ihwan; Muhamad Rinaldhi Tandah
As-Syifaa Jurnal Farmasi Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Urinary tract infection is an infection that comes from bacteria and affects the top or bottom of the urinary tract. Effective treatment can be done by choosing and using appropriate antibiotics. The principle of selecting antibiotics is called cost effective. This study aims to analyze the cost-effectiveness of using ciprofloxacin and ceftriaxone antibiotics in patients with urinary tract infection. The method used is retrospectively quantitative. Data obtained from medical records, and medical payment in the form of direct medical costs of ciprofloxacin and ceftriaxone antibiotics on inpatient with urinary tract infection at General Hospital Anutapura in the period of 2016-2017. The results showed the cost-effectiveness of antibiotics ceftriaxone is more cost effective than ciprofloxacin antibiotics with an ACER value of Rp12.249,5 and ICER value of Rp2.336,5. Based on the cost-effectiveness of antibiotics the results of chi-square test obtained p value = 0.157, it is concluded that there is no significant difference between ciprofloxacin and ceftriaxone.

ANALISIS TINGKAT PENGETAHUAN DAN SIKAP TENAGA KEFARMASIAN DALAM MENCEGAH OBAT RUSAK DAN KADARLUARSA DI RSUD TORA BELO Nurul Ambianti; Muhamad Rinaldhi Tandah; Khusnul Diana; Ratu Balqis
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 9 No 2 (2021): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2021.9.2.5135

Abstract The defective and expired drugs are one of the problems that can reflect the inaccuracy and poor of drug management in a Hospital Pharmacy Unit (HPU). This research was conducted to determine the level of knowledge and attitudes of pharmaceutical personnel in preventing defective and expired drugs at the Regional General Hospital (RGH) Tora Belo. This type of researched is a non-experimental study with cross sectional data collection. The data used are primary data obtained from the results of questionnaires that have been filled out by pharmacist at Tora Belo Hospital. The analysis used in this study is correlation analysis using the Spearman-Rho test, to determine the relationship between the level of knowledge and attitudes of pharmaceutical personnel in preventing defective and expired drugs. The number of samples is 33 people taken by total sampling. Time to collect research data during May-October 2020. From the results of the study, it is known that the level of knowledge of the respondents is dominated by the sufficient category, namely 17 respondents (71.1%), it is known that the attitude of the respondents was included in the very strong category of 18 respondents (85.78%), and the results of the correlation analysis the relationship between the level of knowledge and attitudes of pharmaceutical personnel in preventing defective and expired drugs obtained a significance value of 0.021. So it can be concluded there is a relation between the level of knowledge and attitude of pharmaceutical workers in preventing defective and expired drugs at Tora Belo Hospital.

GAMBARAN PEMBUANGAN OBAT YANG TIDAK DIGUNAKAN DI KALANGAN MASYARAKAT KOTA PALU Nurul Ambianti; Ririen Hardani; Muhamad Rinaldhi Tandah; Handoko Putro
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 6 No. 1 (2022): April 2022
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v6i1.3700

Disposal of drugs that are not used in the community has a very negative impact on the environment. Many drugs are not used and become a big problem, some of which can cause contamination to the environment and disrupt the ecosystem. This study aimed to describe the description of the procurement, use, storage, disposal of drugs as well as public attitudes and information about drugs that are not used, namely damaged and expired among the people of Palu City. This study was a cross-sectional with a population of 84,374 households and a sample of 100 households in Palu City from February to April 2021. This study conducted using the convenience sampling. The independent variable in this study was drug disposal and the dependent variable was drugs that were not used. The data obtained from the questionnaire then analyzed descriptively. The result obtained that many of people bought drugs at pharmacies (78%) with reasons of wanting to buy of their own volition (38%), storing drugs in medicine boxes (56%), throwing drugs in public trash (78%) and respondents think that the improper disposal of unused and expired drugs can have an impact on the environment (70%) because many respondents have never received education related to drug disposal (65%). The majority of people throw away unused or expired drugs that they get from pharmacies in public trash and because of the lack of information regarding the disposal of drugs they get which can have a bad impact on the surrounding environment. Â KeywordsÂ Â Â Â Â Â Â Â : expired drug, drug disposal, unused drug

TINGKAT PENGETAHUAN MAHASISWA UNIVERSITAS TADULAKO TERHADAP SWAMEDIKASI PENYAKIT GASTRITIS Ririen Hardani; Muhamad Rinaldhi Tandah; Chindy Bestari Rataba
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 6 No. 1 (2022): April 2022
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v6i1.3730

Self-medication is carried out as an effort for patients to maintain and pay attention to their own health. Knowledge in self-medication of gastritis is important to have. It can support the use of drugs correctly and appropriately in choosing drugs because if the drug is used incorrectly it can cause the situation to become unfavorable. The purpose of the study was to determine the level of knowledge of students, use of drugs and sources of information on gastritis drugs and the relationship between age and sex factors on the level of knowledge of Tadulako University students in self-medication of gastritis. Type of research was a descriptive cross-sectional with a population of 38,702 a sample of 404 people by purposive sampling. The independent variables in this study were sociodemographic factors, while the dependent variable was the level of students' knowledge of gastritis self-medication. The data source used is primary data by filling out a questionnaire through Google Form. The data was analyzed by univariate and bivariate analysis, namely the chi-square test. A total of 83 respondents (20.5%) had a good level of knowledge, 112 (27.7%) were classified as moderate and 209 (51.7%) were quite. The use of gastritis drugs consumed was categorized as good with an average value of 85%, the source of drug information obtained was based on personal/family experience as much as 37% and there was no relationship between the level of knowledge of self-medication for gastritis of Tadulako University students with age (value 0.116 > 0.005) and gender (value 0.452 > 0.005). The level of knowledge was classified as good, the use of drugs is categorized as good and the dominant source of information is obtained based on personal/family use and there is no significant relationship between age and gender factors on the level of knowledge. Â KeywordsÂ Â Â Â Â Â Â Â Â Â Â Â Â Â : Gastritis, Tadulako University Students, Use Of Drug, Self-Medication, Level Of Knowledge

INTRODUCTION TO THE PHARMACY PROFESSION IN EARLY CHILDREN AT AL-HIJRAH ORPHANAGE SIGI Muhamad Rinaldhi Tandah; Khusnul Diana; Arya Dibyo Adisaputra; Setiawati Fadillah
Journal of Health Community Service Vol. 2 No. 3 (2022): Journal of Health Community Service: 2022 September
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/jhcs.v2i3.2983

The pharmacist profession is closely related to drugs, both in drug manufacture, drug management and drug use in society. Introducing the pharmacist profession to the public, especially in early childhood, is important to introduce and increase early childhood knowledge on how to get, use, store and dispose of drugs properly (DAGUSIBU). This community service activity was carried out at the Al-Hijrah Orphanage, Sigi Regency with the target of all students in the orphanage. The method used was lecture method, namely by explaining information about how to get, use, store and dispose of drugs (DAGUSIBU). This service activity, it began with introducing the service team along with a description of the work being carried out, then continued by explaining the material. The material presented was about the duties and functions of pharmacists in the community, then material on how to get, use, store and dispose of drugs (DAGUSIBU). At the end of the activity, a game was held in the form of questions about the material that has been explained to the participants. There were several things about the use of drugs that are already known and knowledge was getting better after these activities were carried out.

STUDI TUMBUHAN BERKHASIAT OBAT PADA SUKU DONDO DI KECAMATAN OGODEIDE, KABUPATEN TOLITOLI, PROVINSI SULAWESI : Study of Drug Effective Plants on The Dondo Tribe in Ogodeide District, Tolitoli Regency, Central Sulawesi Province Syariful Anam; Agustinus Widodo; Muhamad Rinaldhi Tandah
Biocelebes Vol. 16 No. 2 (2022)
Publisher : Biology Department, Mathematics and natural science, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/bioceb.v16i2.16063

The Dondo Tribe is an indigenous tribe in Ogodeide District. The Dondo Tribe still uses traditional medicine to treat various diseases. The high trust of the Dondo people towards the use of traditional medicine makes people prefer to use traditional medicine. This study aimed to determine the types, parts, and methods of use of plants that have been used as traditional medicine by the bolrians of the Dondo tribe, Ogodeide District, Tolitoli Regency, Central Sulawesi Province. This type of research was descriptive qualitative and the sampling technique was purposive sampling, with structured interview techniques on 11 informants by filling out questionnaires with supporting documentation. The results of the study found that as many as 40 species of plants used as traditional medicine by the bolrians of the Dondo tribe in Ogodeide District which are still preserved today. The percentages of the most widely used plant parts were leaves 55%, stems 11%, rhizomes 11%, roots 5%, fruit 5%, herbs 5%, bark 2%, twigs 2%, tubers 2% and flowers 2%. The percentage of how to use plants as traditional medicine is 65% taken, 26% affixed, 3% seen, 3% washing and 3% smeared.

Co-Authors Abdul Rahman Razak Adisaputra, Arya Dibyo Agustinus Widodo Alwiyah Mukaddas Alwiyah Mukaddas Amelia Rumi Anggraeni Agus Apriyanti Anastasia Arizah Maulidyah Arya Dibyo Arya Dibyo Adisaputra Arya Dibyo Adisaputra Aviva Kumala Basuki, Muhamad Chindy Bestari Rataba Christin Agnes Mega Diwayani Deviani Widnesari Dewi Angriani Fatimah Azzahrah Firdawat Amir Parumpu Firdawati Amir Parumpu Gaby Nathania Angela Mangoting Handoko Putro Hidayatullah Hidayatullah Ihwan Ihwan Ihwan Ihwan Ingenida Hadning Khusnul Diana Khusnul Diana Khusnul Diana Khusnul Diana Khusnul Diana Khusnul Diana Khusnul Diana Khusnul Diana Khusnul Diana Khusnul Diana, Khusnul Meliani Putri Muhammad Heyqal Wirakarsa Muzna Muzna Ni Luh Yeni Safitri Nina Nurlin Nur Ikhlas Nurhafifah Wulandari Kassa Nurlina Ibrahim Nurul Ambianti Nurul Ambianti Nurul Ambianti Nurul Ambianti Raiza Aulia Ratu Balqis Ririen Hardani Sarlina Sarlina Setiawati Fadillah Shella Monica Siti Atika Sri Ayu Noviyanti Syariful Anam Tri Novrianti Djanggola Wirda Suci Ramdhani, Wirda Suci Yuliet Yuliet Yusriadi Yusriadi Zulfiah Zulfiah

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