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ISSN : - EISSN : 25408844 DOI : -

Core Subject : Health,

Medicine & Pharmacology

JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.

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Search results for , issue "Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )" : 15 Documents clear

THE EFFECT OF CLIMBING UP AND DOWN STAIRS EXERCISE ON VO2 MAX IN YOUNG ADULTS (AGE 18-22 YEARS) Anafatun Ihtammaliya; Yosef Purwoko; Buwono Puruhito; Yuswo Supatmo
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background : One of the example of aerobic exercise that is easy and safe is climbing up and down stairs. But with time, people prefer using escalators or elevators to stairs. Whereas, climbing up and down stairs exercise can improve physical fitness which can be assessed from the VO2 max. Aim : To find out the effect of climbing up and down stairs exercise on VO2 max in young adults. Method : This research used Quasi Experimental with pre-test and post-test non-equivalent group method. The sample was medical students of Faculty of Medicine, Diponegoro University (n=36) age 18-22 years that meet the inclusion criteria. The sample was divided into 2 groups, control and treatment groups each consisting of 18 people. The VO2 max was assessed using Multistage Fitness Test (Bleep Test). Statistical analysis with Saphiro-Wilk test, paired T test, Wilcoxon test, unpaired T test, and Mann Whitney test. Result : There was a significant difference of VO2 max before and after climbing up and down stairs exercise in experimental group (p=0.001) and not significant in control group (p=0.181). There was a significant difference of the difference in VO2 max pre-posttest in experimental group and control group (p = 0.001). Conclusion : Six weeks of climbing up and down stairs exercise increases VO2 max in young adults.Keywords : VO2 Max, Climbing Up and Down stairs Exercise, Multistage Fitness Test (Bleep Test)

TINGKAT KETAHANAN HIDUP 2 TAHUN PASIEN ADENOKARSINOMA PARU BERDASARKAN SIFAT MUTASI GEN EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR) Muhammad Agung Wibowo Wicaksono; Fathur Nur Kholis; Fanti Saktini
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Latar Belakang: Kanker paru merupakan penyakit keganasan dengan angka mortalitas tertinggi di dunia, yaitu sebesar 1.590.000 kematian di tahun 2012. Di Indonesia, kanker paru menempati peringkat ke-3 penyakit kanker terbanyak. Adenokarsinoma merupakan jenis kanker paru dengan jumlah kejadian terbanyak, yaitu 40% dari seluruh kanker paru. Faktor risiko terjadinya kanker paru meliputi umur, merokok, terpapar oleh polusi udara di rumah atau tempat kerja, dan mempunyai riwayat keluarga dengan kanker paru. Kanker paru jenis adenokarsinoma sangat erat terkait dengan mutasi Epidermal Growth Factor Receptor (EGFR), yaitu 15-20% dari kasus adenokarsinoma paru. Metode: Penelitian ini menggunakan desain cross-sectional dengan mengambil data dari rekam medik pasien RSUP Dr. Kariadi Semarang yang didiagnosis adenokarsinoma paru. Data tersebut kemudian disusun dan dilakukan analisis statistik dengan uji chi-square dan uji regresi logistik terkait hubungan faktor risiko terhadap mutasi EGFR. Hasil: Dari 97 sampel penderita adenokarsinoma paru, didapatkan 36 subjek dengan mutasi EGFR (37,1%) dan 61 subjek non mutasi EGFR (62,9%). Terjadinya mutasi EGFR berhubungan dengan jenis kelamin perempuan (p = 0,009) dan non perokok (p= 0,028). Tidak ada hubungan bermakna antara mutasi EGFR dengan faktor umur (p = 0,667), paparan pekerjaan (p = 0,418), dan riwayat keluarga (p = 0,371). Dari uji multivariat, didapatkan hasil bahwa jenis kelamin perempuan merupakan faktor paling berisiko terhadap kejadian mutasi EGFR (p = 0,010). Simpulan: Terdapat perbedaan faktor risiko pada penderita adenokarsinoma paru dengan mutasi EGFR dan non mutasi EGFR. Kelompok dengan jenis kelamin perempuan dan non perokok lebih berisiko terhadap terjadinya adenokarsinoma paru dengan mutasi EGFR, sedangkan kelompok dengan jenis kelamin laki-laki dan perokok lebih berisiko terhadap terjadinya adenokarsinoma paru non mutasi EGFR.Kata Kunci : Adenokarsinoma paru, faktor risiko, mutasi EGFR

THE EFFECT OF FORWARD LEAN POSITION AND PURSED LIP BREATHING ON PEAK EXPIRATORY FLOW IN ACTIVE SMOKER Lutfia Zein Amalia; Erna Setiawati; Rahmi Isma Asmara Putri
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background: Chronic exposure to tobacco smoke cause activation of macrophages which contribute to the release of inflammatory mediators and the establishment of Chronic Obstructive Pulmonary Disease (COPD). In COPD, the airway become narrowed and result in reduced peak expiratory flow (PEF). One form of treatment that improve pulmonary functions and can be given to active smokers is by giving forward lean position and pursed lip breathing (PLB). Aim : To analize the differences of PEF before and after performing forward lean position and PLB both acute and chronic types in active smokers. Methods: The study was quasi-experimental with pretest posttest, respondents of this study are 18 active smokers with purposive sampling. The instrument used in the research are scales, microtoise and peak flow meter. Method used for data analysis was paired and unpaired t-test. Results: PLB increases PEF with the mean of PEF 28.89±47.08 in acute phase and 28.34±40.84 in chronic phase. The combination of PLB and forward lean position increase PEF with the mean of PEF 30.00±34.91 in acute phase and 46.12±89.60 in chronic phase. Conclusions: There were not statistically significant difference of PEF in acute and chronic phase in group A between before and after intervention (p >0.05). There was not statistically significant difference of PEF in chronic phase in group B between before and after intervention. There was statistically significant difference of PEF in acute phase in group B between before and after intervention. The combination of forward lean position and PLB showed to have a better effect on increasing the value of PEF than PLB without combination both acute and chronic types in active smokers.Keywords: Pursed lip breathing, forward lean position, peak expiratory flow, active smokers

ASSOCIATION OF THIRD TRIMESTER MATERNAL HEMOGLOBIN WITH MEASUREMENT OF NEWBORN’S ANTRHROPOMETRY Rahman, Farhan Aulia; Anantyo, Dimas Tri; Dewantiningrum, Julian; Haryana, Bambang
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background: More than 20 million babies are born each year with a body weight of less than 2500 g, and 17% of all births in developing countries. Birth weight plays a role in mortality and morbidity, development and, future health of children. Low birth weight is a significant risk factor for infant death and other physical disorders. Anemia that occurs in maternal can increase the risk of mortality, perinatal morbidity and can affect the state of newborns. Anemia in maternal is related to low gestational age, low birth weight, and increased risk of small infants for gestational age. Research on the relationship of maternal’s hemoglobin levels in third trimester to anthropometric measurement of newborns has never been carried out at Rumah Sakit Nasional Diponegoro (RSND). Objective: This study aims to determine relationship between maternal’s hemoglobin levels in third trimester with anthropometry of newborns. Method: This research was a study with cross sectional design. Data is collected from medical records at RSND. Babies born viewed medical records to determine inclusion criteria in the study. Anthropometric data were collected for newborns and the third trimester hemoglobin level was recorded in pregnant women. Assosiation analytic was performed with chi square test. Results: There was a significant relationship between maternal’s hemoglobin levels in third trimester with measurements of newborn weight, body length, and head circumference. Conclusion: Maternal’s hemoglobin in third trimester affect the measurement of weight, body length, and head circumference neonates.Keywords: anemia, hemoglobin, anthropometry, maternal, newborn

THE LEVEL OF UNDERSTANDING OF GENERAL DOCTORS AND SPECIALIST DOCTORS IN THE MAKING OF VISUM ET REPERTUM IN SEMARANG CITY Wahyu Purnomo Adji; Intarniati Nur Rohmah; Julia Ike Haryanto; Edward Kurnia Setiawan
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background: Visum et repertum is a form of report addressing the condition of human bodies, both living and dead. The reality is that in the field there are still mistakes in making VeR that can influence court decisions, this is also reinforced by the findings of research data that had been done before. Aim: To determine the level of understanding of general doctors and specialists (Obstetrics and Gynecology and Surgery) in making VeR in Semarang City. Methods: Descriptive study of 34 doctors consisting of 16 general doctors, 10 surgeons and 8 obstetricians and gynecologists. The procedure of the research involved collecting data using a questionnaire consisting of the VeR section. The data are sorted according to the group of respondents and description is done. Results: Descriptive analysis showed that the level of understanding of 16 general doctors was categorized as medium with a value of 71.43 % with: 8 doctors (50 %) good questionnaire value, 6 doctors (37.5 %) medium questionnaire value, and 2 doctors (12.5 % ) bad questionnaire value. The level of understanding of 10 surgeons is categorized as good with a value of 76.43 % with: 4 doctors (40 %) good questionnaire value, 6 doctors (60 %) medium questionnaire value, and no bad value. The level of understanding of 8 obstetrics and gynecology specialists was categorized as good with a value of 76.17 % with: 4 doctors (50 %) good questionnaire value, 4 doctors (50 %) medium questionnaire value, and no bad scores. Conclusion: The level of understanding of general doctors was medium with a value of 71.43%, the surgeon specialist was categorized good with a value of 76.43% and obstetricians and gynecology specialists were categorized good with a value of 76.17%.Keywords: level of understanding, visum et repertum

THE DIFFERENCE OF ATTENTION LEVEL BEFORE AND AFTER SKIPPING EXERCISE IN MEDICAL FACULY OF DIPONEGORO UNIVERSITY STUDENTS Azizah Indria Putri; Buwono Puruhito; Dodik Pramono; Endang Kumaidah
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background: Skipping exercise is a kind of physical exercise which is inexpensive and easy to do. Skipping is one of many kinds of aerobic physical exercise. Aerobic physical exercise have been known from its function in improving cognitive function including attention in human brain. However there haven’t been any research which discusses about the difference of attention level before and after skipping exercise in Medical Faculty of Diponegoro University. Aim: To find out a difference of attention level before and after skipping exercise. Methods: This study conducted in quasi experimental pre-test and post-test nonequivalent group method. This study was conducted in May until July 2019. The subjects were 46 male students of Medical Faculty of Diponegoro University, divided in 2 groups. Experimental group was instructed to do 6 weeks of skipping exercise (3 times in a week) and control group was instructed to not do any exercise. Attention level was measured with software Attention Network Test a day before skipping exercise started and a day after skipping exercise ended. Significance was analyzed by Paired T Test/Wilcoxon and Independent T Test/Mann-Whitney. Results: There were no significant difference of alerting and orienting score before and after skipping exercise in both experimental and control group. Meanwhile, there was significant difference of executive control score (p=0,001) that could be seen from its first mean score 94,296 and then the score declined to be 65,130 in the second test. It indicated an increasing executive control function. Conclusion: Six weeks of skipping exercise increases executive control function of attention.Key Words: Skipping exercise, attention level, alerting, orienting, executive control

RELATIONSHIP BETWEEN THE INTENSITY OF SOCIAL MEDIA USAGE WITH SLEEP QUALITY Rizki Alfarizi; Titis Hadiati; Hang G. Asikin; Widodo Sarjana
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background: Social media has become a part of human daily life, including students. The high intensity of social media usage can affect various aspects of life, one of which is the quality of sleep. The high intensity of social media usage is thought to be related with poor sleep quality. This study analyzes the relationship between the intensity of social media usage and sleep quality. Objective: To know the relationship between the intensity of social media usage with sleep quality in dental students. Method: This research was an observational analytic study with a cross-sectional design. The sample was students of the Dentistry Study Program at Faculty of Medicine, University of Diponegoro (n = 79). The intensity of social media usage was measured using the Social Network Time Use Scale and sleep quality was measured using the Pittsburgh Sleep Quality Index. Measurement of dependent and independent variables was done once at a time. Result: Among respondents, 34,2% were reported using social media with low intensity, 58,2% with average intensity, and 7,6% with high intensity; and 34,2% of respondents had good sleep quality and 65,8% had poor sleep quality. There was a significant relationship between SONTUS scores and PSQI global scores on respondents with the result of p = 0.02 (p <0.05) which indicates that there was a significant linear relationship. Likewise, the relationship between SONTUS scores and gender with the result of p = 0.03 (p <0.05) which also indicates a significant relationship between the two. Conclusion: The intensity of social media usage has a relationship with sleep quality and gender.Keywords: The Intensity of Social Media Usage, Sleep Quality, Social Networking Time Use Scale, Pittsburgh Sleep Quaity Index

THE DIFFERENCE OF SLEEP QUALITY BEFORE AND AFTER SKIPPING EXERCISE IN MEDICAL STUDENTS OF DIPONEGORO UNIVERSITY Julsyawiah Novthalia; Buwono Puruhito; Dodik Pramono; Endang Kumaidah
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background : The many tasks that put upon the medical students require them to have a good sleep quality. Medical students generally have poor sleep quality. One way to improve sleep quality is to perform effective aerobic physical activities such as skipping. Aim : To explore the difference in sleep quality before and after skipping exercise in Medical Student of Diponegoro University. Methods : This study was a quasi-experimental with pre-test and post-test non-equivalent group. The samples were students of Faculty of Medicine, Diponegoro University (n = 48) aged 18-22 years who met the inclusion criteria. The sample was divided into 2 groups: control and treatment groups, each consisting of 24 students. Sleep quality score was measured using the Pittsburgh Sleep Quality Index (PSQI). The normality test was performed using the Shapiro-Wilk test. Hypothesis testing of sleep quality score before and after skipping exercise in the control group was performed using the Wilcoxon test, while in the treatment group using the paired t-test. The difference in sleep quality score between control and treatment groups was performed using the Mann-Whitney test. Results : The pre-test PSQI score in the control group is 6.88 ± 1.872 while in the treatment group is 7.63 ± 1.996. The results of the statistical test showed that the difference is not significant (p>0.05). The post-test PSQI score in the control group was 7.92 ± 2.888 while in the treatment group was 4.58 ± 1.886. The results of the statistical test showed that the difference is significant (p<0.05). In the control group, there is a slight increase in PSQI score which is not significant (p>0.05), while in the treatment group there is a significant decrease in PSQI score (p<0.05). Conclusion : There is a significant difference in the sleep quality score between control and treatment groups; the sleep quality of the treatment group is better than the control group.Key Words : Sleep quality, Skipping exercise, Pittsburgh Sleep Quality Index (PSQI)

DIFFERENCES OF PEAK EXPIRATION FLOW RATE (PEFR) BETWEEN BRISK WALKING AND HIGH INTENSITY INTERVAL TRAINING (HIIT) IN YOUNG ADULTS Vania Nazhara Fitriana; Yosef Purwoko; Sumardi Widodo; Tanjung Ayu Sumekar
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background : Sedentary lifestyle makes people having less physical activities that may lead to the reduce lung function. Peak expiratory flow rate (PEFR) was used to measure lung function. High Intensity Interval Training (HIIT) is a high-intensity aerobic exercise, while brisk walking is an moderate-intensity aerobic exercise. The aim of this research is to determine the difference of PEFR between HIIT and brisk walking, that could depict lung function. Method : This research used quasi experimental with pre-test and post-test comparison group design. The samples were medical students at Diponegoro University, who had inclusion criteria and did not have exclusion criteria. This research used samples of 3 groups that contained of control group, HIIT, and brisk walking with 14 people in each group. Groups of HIIT and brisk walking got 3 times of intervention in each week, for 6 weeks. Measurement of PEFR was using Miniwright Peak Flow Meter. The normality of numerical scaled data was tested by using Saphiro-Wilk method, to find abnormal data that was tested by using Mann Whitney Method. Results : The average post-test of PEFR in HIIT was (397.14±33.738), while in brisk walking was (370.14±34.851), and in the control group was (327.78±29.271). The increase in PEFR between the HIIT and the brisk walking group after statistical testing was p = 0.000 (p <0.005), which shows a significant difference. Conclusion: There is a significant difference in the PEFR between HIIT group and brisk walk in early adults that could describe a person's lung function.Keywords : Lung Function, PEFR, HIIT, Brisk walking.

DIFFERENCES OF DEPRESSION LEVELS IN TEMPORAL LOBE EPILEPSY AND EXTRA TEMPORAL LOBE EPILEPSY PATIENTS : CASE STUDY IN POST EPILEPSY SURGERY PATIENTS Muhammad Rully Zen; Zainal Muttaqin; Yuriz Bakhtiar; Dimas Sindhu Wibisono
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 1 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Introduction: Depression is a common condition in epilepsy patients, especially temporal lobe epilepsy both before and after epilepsy surgery. However, not many studies have examined the depression status of patients undergoing surgery outside the temporal lobe (extratemporal resection). Differences in levels of depression between temporal lobe epilepsy (TLE) and extra-TLE patients are also not well known, so the effect of surgery on mood disorders in this group of epilepsy patients needs to be further investigated. Aim: This study aims to study whether there are differences in depression rates for TLE and extra-TLE patients in case studies of post-epileptic surgery patients. Method: The design of this study was cross sectional by conducting research on patients with temporal lobe epilepsy (n = 29) and extra temporal epilepsy patients (n = 24) from 1999 to 2019. The study was conducted at the Hospitals in Semarang. Researchers recorded depression levels using the Beck Depression Inventory - II (BDI-II) after the patient had surgery. The collected data will be analyzed using the parametric 2 independent samples t test. Results: 53 patients who were subject were 29 TLE patients (54.7%) and 24 Extra TLE patients (45.3%). TLE patients who had normal BDI-II results were 14 patients (48.3%), mild depression by 6 patients (20.7%), moderate depression by 8 patients (27.6%) and severe depression by 1 patient (3,4%) while the Extra TLE patients showed normal results of 11 patients (45.8%), mild depression of 8 patients (33.3%), moderate depression of 4 patients (16.7%) and severe depression of 1 patient ( 4.2%). 2 independent samples t test showed insignificant results, namely p = 0.831. Conclusion: There are differences of depression level between TLE and Extra TLE cannot be confirmed, because there are many factors such as the duration of epilepsy and seizure frequency that influence patients. Multifactorial explanation for the depression in patients with TLE and extra TLE must be investigated.Keywords: TLE (Temporal Lobe Epilepsy), extra-TLE, Depression

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