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Sosialisasi DAGUSIBU Untuk Meningkatkan Rasionalitas Penggunaan Obat Bagi Masyarakat Kerandangan Desa Senggigi Wahida Hajrin; Windah Anugrah Subaidah; Yohanes Juliantoni
Jurnal Pengabdian Magister Pendidikan IPA Vol 3 No 2 (2020): .
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (483.478 KB) | DOI: 10.29303/jpmpi.v3i2.492

Abstract

Senggigi village community has limitations in obtaining information about health, one of which is DAGUSIBU. DAGUSIBU is a way to get, use, store and dispose of medicines properly. The aim of this socialization was to inform about DAGUSIBU to the community so that medicines can be used rationally. The method used in the socialization is the delivery of material and direct examples related to the use of medicines that require special methods. The participants were very enthusiastic to attend the socialization, as evidenced by the many questions related to DAGUSIBU raised. This socialization increased participant’s knowledge about DAGUSIBU, they understand how to get, use, store and dispose of medicines in the right way.
Pelatihan Pembuatan Masker peel-off Lidah Buaya (Aloe vera) Untuk Mengatasi Efek Sunburn Windah Anugrah Subaidah; Wahida Hajrin; Yohanes Juliantoni
Jurnal Pengabdian Magister Pendidikan IPA Vol 3 No 2 (2020): .
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.801 KB) | DOI: 10.29303/jpmpi.v3i2.511

Abstract

Tingginya angka pengangguran di kota Mataram diantaranya kurangnya pendidikan dan keterampilan dari tenaga kerja. Lulusan SMA membutuhkan keterampilan untuk menciptakan lapangan pekerjaan dan mengurangi angka pengangguran. Salah satu peluang wirausaha adalah dengan membuat masker peel off lidah buaya (Aloe vera). Hal ini dilatar belakangi oleh intensitas matahari yang tinggi didaerah Indonesia yang cenderung menimbulkan efek negatif pada kulit terutama sunburn. Bahan baku lidah buaya yang mudah diperoleh dan mempunyai aktivitas sebagai antiinflamasi dari sunburn. Metode pelaksanaan pengabdian untuk memecahkan masalah mitra siswa SMAIT Anak Sholeh Mataram terdiri dari tiga tahapan yaitu persiapan kegiatan, pelaksanaan kegiatan, dan monitoring dan evaluasi. Hasil kegiatan pengabdiaan menunjukkan bahwa peserta memberikan tanggapan yakni peserta merasa pelatihan ini bermanfaat, proses pembuatan sediaan mudah dan pesesrta akan membuat masker lidah buaya. Tanggapan lainnya yakni penyajian materi menarik, materi yang disajikan mudah dipahami dan secara umum peserta puas terhadap kegiatan pengabdian masyarakat pembuatan masker lidah buaya ini
Formulasi dan Uji Aktivitas Antiradikal Bebas Emulgel Ekstrak Daun Juwet (Syzygium cumini L.) dengan Metode DPPH (Diphenilpycrylhydrazil): Formulation and Investigation of Antiradical Activity in Emulgel Containing Syzygium cumini L. Extract with DPPH Method M. Elyadi; Windah Anugrah Subaidah; Handa Muliasari
Jurnal Sains dan Kesehatan Vol. 3 No. 3 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.231 KB) | DOI: 10.25026/jsk.v3i3.565

Abstract

Radikal bebas merupakan molekul sangat reaktif yang dapat menyebabkan kerusakan sel, kerusakan jaringan dan proses penuaan dini. Perlindungan terhadap serangan radikal bebas membutuhkan senyawa antioksidan. Juwet (Syzygium cumini L.) merupakan salah satu tumbuhan lokal yang dapat menjadi sumber antioksidan alami. Penggunaan daun juwet sebagai antioksidan akan lebih mudah dalam bentuk sediaan emulgel. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antiradikal bebas ekstrak daun juwet serta menformulasikannya menjadi emulgel. Penelitian yang dilakukan meliputi ekstraksi dengan metode maserasi menggunakan pelarut etanol 70%, lalu dilakukan uji kualitatif fitokimia dan uji aktivitas antiradikal bebas pada ekstrak. Setelah itu dilakukan formulasi emulgel, uji sifat fisik serta uji aktivitas antiradikal bebas pada emulgel dengan metode DPPH. Hasil penelitian yang diperoleh menunjukan bahwa esktrak etanol daun juwet positif mengandung flavonoid, tanin dan polifenol serta memiliki aktivitas antiradikal bebas yang sangat kuat dengan nilai IC50 sebesar 40,36 ?g/mL dan sediaan emulgel ekstrak daun juwet memiliki aktivitas antiradikal bebas yang kuat dengan nilai IC50 sebesar 94,44 ?g/mL. Hasil uji sifat fisik dari formula sediaan emulgel telah memenuhi syarat pH, homogenitas,daya sebar, dan daya lekat.
Ekstraksi dan Penetapan Kadar Glukomanan dari Umbi Porang (Amorphophallus muelleri Blume) Menggunakan Metode DNS: Extraction and Determination of Glucomannan Contents from Porang Tuber (Amorphophallus muelleri Blume) Using DNS Method Novita Eliya Wardani; Windah Anugrah Subaidah; Handa Muliasari
Jurnal Sains dan Kesehatan Vol. 3 No. 3 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.66 KB) | DOI: 10.25026/jsk.v3i3.574

Abstract

Glukomanan merupakan polisakarida yang tersusun oleh unit ?-D-glukosa dan ?-D-mannosa yang terikat dengan gugus asetil melalui ikatan b-1,4 dan b-1,6 glikosida. Glukomanan terdapat pada dinding sel beberapa spesies tumbuhan terutama diekstraksi dari umbi genus amorphophallus spp. Secara komersial, pemanfaatan glukomanan sangat luas yaitu khususnya dalam industri farmasi digunakan sebagai bahan pengisi, pengikat tablet, pengental, gelling agent, film former, coating materials, emulsifier, stabilizer dan drug delivery system. Tujuan dari penelitian ini yaitu untuk menentukan kadar glukomanan yang diekstraksi dari umbi porang di Nusa Tenggara Barat. Penelitian yang dilakukan meliputi pembuatan tepung porang, ekstraksi glukomanan menggunakan pelarut etanol 60% dan uji kuantitatif glukomanan dengan metode DNS (Dinitro Salisilic Acid) menggunakan instrumen spektrofotometer uv-vis. Hasil penelitian yang diperoleh yaitu rendemen tepung glukomanan sebesar 66,26% dengan kadar glukomanan hasil pemurnian sebesar 38,5312±0,5%.
Formulasi dan Karakterisasi Nanopartikel Kitosan Ekstrak Sari Buah Juwet (Syzygium cumini) menggunakan metode Gelasi Ionik: Formulation and characterization of Chitosan Nanoparticle of Juwet (Syzygium cumini) Fruit Extract Using Ionic Gelation Method Wahida Hajrin; Wayan Cintya Ganes Budastra; Yohanes Juliantoni; Windah Anugrah Subaidah
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.033 KB) | DOI: 10.25026/jsk.v3i5.614

Abstract

Syzygium cumini (S. cumini) fruits have a high potential to be developed as medicine because of their polyphenol content. Polyphenol is easily degraded so that its stability needs to be increased through the formation of nanoencapsulation. The aim of this study was to determine the formula of SBJ nanoparticles which has good characteristics. The formula was determined using a pseudoternary phase diagram based on the %transmittant and %EE. Nano SBJ was characterized for % transmittant ,% EE, polydispersity index, and zeta potential. The formula of Nano SBJ obtained chitosan, SBJ extract, and Na TPP were 0.347%, 0.627%, and 0.047%, respectively. The characterization of Nano SBJ were % EE was 30.72%, the mean diameter of particles was 138.1 ± 7.9 nm, PdI was 0.839 ± 0.043, and zeta potential was 34.9 ± 1.2 mV. Nano SBJ has nano-sized particles and has good stability, but low in entrapment efficiency.
Emulgel formulation of wild cherry leaves (Antidesma bunius L. Spreng) extract and its antioxidant activity Windah Anugrah Subaidah; Yayuk Andayani; Dewa Ayu Puspaning Kumaradewi
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 10 No 2 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo (in progress)
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2022.10.2.4036

Abstract

Background: The ethanol extract of wild cherry leaves (Antidesma bunius L. Spreng) has been studied as a free anti-radical in an emulgel formulation. The purpose of this study is to determine the physical properties of an emulgel made from an ethanol extract of wild cherry leaves, as well as its anti-radical activity. Methods: The maceration method was used to extract wild cherry leaves in 96% ethanol, which were then evaporated with a rotary evaporator. An emulgel was prepared to contain a 3.56% thick extract. The physical properties of the emulgel were evaluated consisting of the organoleptic test, pH test, homogeneity test, spreadability test, and adhesion test. The DPPH was used to test free anti-radical activity. Results: The emulgel of the ethanol extract of wild cherry leaves had a yellowish-green, thick texture, a distinct aroma of the extract, was homogeneous, pH 6, spreadability ranged from 4.4-6.2 cm, and adhesion of 5.467 0.83 cm. Emulgel had a very weak antioxidant activity with an IC50 of 6238.41 ppm. Conclusion:
Sosialisasi penanaman dan pemanfaatan tanaman obat keluarga (TOGA) Nana Mardiana; Windah Anugrah Subaidah
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 2 (2022): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v3i2.161

Abstract

Indonesian people have used herbal plants for generations to overcome health problems, but some people are still lacking in obtaining health services. Tenggareng hamlet, North Jenggik Village, Montong Gading Dstrict, East Lombok Regency, West Nusa Tenggara Province is one of the hamlets that has not optimized the yard as land for growing herbal plants. The yard house is suitable land for planting various types of plants. The purpose of this activities was to increase the knowledge of the community, especially about the cultivation and use of medicinal plants. The method used in this community services were lecturing and discussion method. Involving 42 participants. The results of community services are increasing people knowledge and skills related to the planting and utilization of herbal plants. This can be seen from the occurrence of interactive discussions. In conclusion, by conducting socialization and utilization of Family Medicinal Plants can increase public understanding to optimize Family Medicinal Plants.
Emulgel formulation of wild cherry leaves (Antidesma bunius L. Spreng) extract and its antioxidant activity Windah Anugrah Subaidah; Yayuk Andayani; Dewa Ayu Puspaning Kumaradewi
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 10 No 2 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2022.10.2.4036

Abstract

Background: The ethanol extract of wild cherry (Antidesma bunius L. Spreng) leaves has been studied as a free anti-radical in an emulgel formulation. The purpose of this study is to determine the physical properties of an emulgel made from an ethanol extract of wild cherry leaves, as well as its anti-radical activity. Methods: The maceration method was used to extract wild cherry leaves in 96% ethanol, which were then evaporated with a rotary evaporator. An emulgel was prepared to contain a 3.56% thick extract. The physical properties of the emulgel were evaluated consisting of the organoleptic test, pH test, homogeneity test, spreadability test, and adhesion test. The DPPH was used to test free anti-radical activity. Results: The emulgel of the ethanol extract of wild cherry leaves had a yellowish-green, thick texture, a distinct aroma of the extract, was homogeneous, pH 6, spreadability ranged from 4.4-6.2 cm, and adhesion of 5.5 second. Emulgel had a very weak antioxidant activity with an IC50 of 6238 ppm. Conclusion: Further optimization of the formulation and storage conditions may be required to enhance the antioxidant potential of the wild cherry leaf extract emulgel for topical applications.
Formulasi tablet hisap ekstrak etanol daun kemangi (Ocimum sanctum L.) dengan variasi konsentrasi bahan pengikat gelatin Putri Nuryana; Windah Anugrah Subaidah; Agriana Rosmalina Hidayati
Sasambo Journal of Pharmacy Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i1.213

Abstract

Basil leaves (Ocimum sanctum L.) contain secondary metabolites as inhibitors of the growth of pathogenic microbes in the mouth, so they can be used as lozenges. The choice of binder in the formulation is very important, because it can affect the physical properties of the tablet. The purpose of this study was to determine the content of secondary metabolites in basil leaf extract and determine the best formula for lozenges of ethanol extract of basil leaves based on variations in gelatin binding agents. Basil leaves were extracted using the sonication method with 96% ethanol solvent and subjected to phytochemical screening (test tube and TLC). Tablets were formulated using the wet granulation method with variations of gelatin in formula 1 (5%), formula 2 (7.5%), and formula 3 (10%). The physical properties of the granules are evaluated and compressed. The resulting tablets were evaluated for physical properties. The results showed that basil leaves contained compounds belonging to the class of flavonoids, saponins and tannins. The results of the granule flow time test for formula 1 and 2 did not meet the requirements, formula 3 met the requirements for the Indonesian Pharmacopoeia Edition III. The angle of repose, settling, and granule water content tests (formula 1, 2, and 3) met the requirements of the Indonesian Pharmacopoeia Edition III. The results of tablet evaluation in the weight uniformity test for formulas 1, 2, and 3 were 257 mg ± 0.226; 248 mg ± 0.068 and 253 mg ± 0.157. Tablet hardness test of 3.721 kg ± 0.268; 4.221 kg ± 0.929 and 6.636 kg ± 1.035. Tablet friability test of 3.4% ± 0.152; 1.1% ± 0.264 and 0.9% ± 0.1. The disintegration time test was 7.6 minutes ± 2.452; 11 minutes ± 2.154 and 18.6 minutes ± 4.016. From this study it can be concluded that the ethanol extract of basil leaves has secondary metabolites of flavonoids, saponins and tannins. Variations in gelatin binder affect the physical properties of the tablet, where the concentration of gelatin binder is best in formula 3 (10%).
Peran farmasis di industri obat di Indonesia sebagai gambaran lapangan kerja alumni farmasi Universitas Mataram Windah Anugrah Subaidah; Wahida Hajrin; Yohanes Juliantoni
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v4i1.220

Abstract

The unemployment rate rises every year, leading people to seek information for the purpose of gaining and providing jobs, which can be achieved by attending university. Given its bright future prospects, pharmacy is a popular field of study. A pharmacist may work in the industrial sector; according to Ministry of Health data from 2019, Indonesia had up to 230 industry pharmaceuticals. The rise of Indonesia's pharmaceutical industry will require a huge number of employees, especially experienced pharmaceutical professionals. Unfortunately, the results of tracer studies for Pharmacy graduates from the University of Mataram who work in the industrial sector are still quite low. According to a similar survey, a lack of interest in pharmaceutical graduates can be related to a lack of knowledge about the pharmaceutical industry. The purpose of this community service activity is to encourage pharmacy students to work in the pharmaceutical industry. Service activities can be carried out in three stages: preparation, implementation, monitoring, and evaluation. The results of the activity showed that the participants were enthusiastic about the program, as seen in the way they engaged in asking questions and responding to the question from the committee. The result of the evaluation revealed that 93.2% of the participants planned to work in the pharmaceutical industry. As a result, this community service activity is seen to have the potential to help inspire and encourage pharmacy students to pursue careers in the pharmaceutical industry.