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EFFECTIVENESS TEST OF BLACK CUMIN SEEDS (NIGELLA SATIVA) EXTRACT ON THE GROWTH OF KLEBSIELLA PNEUMONIAE AND PSEUDOMONAS AERUGINOSA BACTERIA Nadya Nazimuddin Putri; Linda Chiuman; Chrismis Novalinda Ginting; Ermi Girsang
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 7, No 2 (2021): February 2021
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v7i2.3702

Abstract

Black cumin seeds are known to have beneficial contents as antibacterial. This study aimed to determine the effectiveness of black cumin seed extract (Nigella sativa) on the growth of Klebsiella pneumoniae and Pseudomonas aeruginosa. The method used was the disc diffusion method. The ethanol extract of black cumin seeds gain by maceration method and was made into various concentration (5, 7.5, 10, 12.5, and 15)%. For positive control, ciprofloxacin disc were used and negative control used distilled water. The research model used was in vitro experimental research. The results showed that ethanol extract of black cumin seeds have antibacterial activity against Klebsiella pneumoniae with inhibition zone diameters (4.5, 6.7, 10.1, 11, 12.8) mm, Pseudomonas aeruginosa with inhibition zone diameters (7.5, 12, 12.6, 13.4, 15.6) mm, positive controls respectively (24.3 and 20.7) mm and negative controls (0). It can be concluded that black cumin seed extract has an inhibiting effect on the growth of Klebsiella pneumoniae and Pseudomonas aeruginosa.
EFFECTIVENESS TEST OF ANTI-BACTERIAL LIME JUICE (Citrus aurantifolia) ON SALMONELLA SP BACTERIA IN SALMON FISH (Oncorhynchus nerka) Qori Fadillah; Linda Chiuman; Chrismis Novalinda Ginting; Ermi Girsang
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol 7, No 1 (2020): August 2020
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.003 KB) | DOI: 10.31289/biolink.v7i1.3322

Abstract

Salmonella Sp is a gram-negative pathogens that are often found in marine foods,one of  process of serving  salmon is channeling lime juice, where lime juice is acidic and has phytochemical properties that have anti-bacterial properties. This study aims to explore anti-bacterial effect lime juice on Salmonella thypii bacteria in Salmon. This research is an experimental study using  disc diffusion method. Lime samples that were used were purchased from one of the modern markets in Medan which were made in several series of concentrations using distilled water as a solvent, while the salmon samples used in this study were purchased from one of the Japanese dining restaurants located in Medan City. Meanwhile, isolation of Salmonella thypii bacteria from salmon samples was carried out using nutrient broth and SSA media. The results of this study indicate that differences in concentration indicate the differences in the diameter of the inhibitory zone (P value = 0.000). With the diameter of the widest inhibition zone formed by a concentration of 100% is 15.40 ± 0.44 mm and the smallest diameter is formed by a concentration of 5% which is 7.23 ± 0.55 mm. Thus, it can be concluded that the lime juice has anti-bacterial activity against Salmonella thypii bacteria from salmon.
PENGARUH PENGETAHUAN TENTANG INISIASI MENYUSU DINI TERHADAP PROSES LAKTASI PADA IBU NIFAS DI KLINIK SUNGGAL KOTA MEDAN TAHUN 2017 Chrismis Novalinda Ginting
Jurnal Maternitas Kebidanan Vol. 3 No. 1 (2018)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mother's skin will adjust its temperature to the baby's needs. Warmth during breastfeeding can reduce the risk of death due to hypothermia (cold). Mother and baby feel more calm, so that helps breathing and baby heartbeats more stable. So babies are more rarely fussy. This study aims to determine the effect of knowledge on early breastfeeding initiation of lactation process in postpartum mother at Sunggal Clinic Medan Medan 2017. This research is quasy experimental with pre-test, treatment, and post-test. The population in this study 10 people. Thenik sampling in the study is to use saturated sampling that is as much as 10 people. The results of research conducted on 10 respondents in Sunggal Clinic Medan Medan in 2017 the majority of respondents are well knowledge as many as 8 people (80%), and a knowledgeable minority of 1 person (10%) and less 1 person (10%). With the obtained p-Value of 0.007 so that there is a difference of knowledge about initiation of breastfeeding before and after. The conclusion in this research is that the respondent's knowledge about Initiation of Early Breastfeeding on lactation process at Sunggal Clinic is good knowledge, and it is suggested to the respondent to further improve the knowledge about IMD.
LITERATUR REVIEW : EFEKTIVITAS PLATELET-RICH PLASMA TERHADAP PERBAIKAN ORGAN GINJAL Linda Chiuman; Chrismis Novalinda Ginting
Jurnal Maternitas Kebidanan Vol. 6 No. 2 (2021): Jurnal Maternitas Kebidanan
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jumkep.v6i2.2052

Abstract

Kidney Failure is a health condition that worsen the quality of life. In Acute Kidney Injury and Chronic Kidney Disease there is a damage not only in function but also in the structure of kidney. Platelet Rich Plasma is known to has a lot of benefits as a medical treatment. Platelet Rich Plasma is a plasma that rich in platelets which has the function of regenerating and repairing tissue structures, especially damaged kidneys. This study aimsTo determine the effectiveness of Platelet-Rich Plasma on the improvement of  damaged kidneys. This paper uses a literature study or literature review by searching through Google Scholar or Pubmed using the keywords “Platelet-Rich Plasma”, “Acute Kidney Injury”, “Chronic Kidney Disease” for the last 5 years studies published between 2016 to 2021. Based on the literature search, there were 5 research articles related to the effectiveness of Platelet Rich Plasma on the improvement of damaged kidney, where all studies were tested on experimental animals. Based on the results of the literature study, it can be concluded that there is a relationship between the effectiveness of Platelet-Rich Plasma on the improvement of damaged kidneys in experimental animals.
SUATU STUDI LITERATUR: AKTIVITAS ANTIDIABETIC DARI KULIT JERUK (Citrus sp.) Maya Sari Mutia; Chrismis Novalinda Ginting; OK Yulizal
Jurnal Maternitas Kebidanan Vol. 6 No. 2 (2021): Jurnal Maternitas Kebidanan
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jumkep.v6i2.2054

Abstract

Diabetes mellitus is a chronic metabolic disease, which is not able to secrete insulin in sufficient quantities or the body is unable to use insulin effectively so there is an excess glucose level and immediately suffer from some complications against the organs. Diabetes mellitus can be cured by herb utility which are thought to have compounds that has an antidiabetic effect. Therefore, this literature study discusses the antidiabetic activity of orange peel (Citrus sp.). The literature search was carried out on the Google Scholar search engine which used some keyword included antidiabetic, extract, orange peel, Citrus. In this literature study, there are inclusion and exclusion criteria for selecting journals as literature sources. The results of 12 literatures review that orange peel had antidiabetic activity by decrease blood glucose levels in some animal trials that had received an effective dose of orange peel extract in each of the reviewed studies. Hence, it can be concluded that various type of Citrus peels has antidiabetic effect.
KONTEKSTUALISASI PROSES KEPERAWATAN DIABETES MELLITUS TIPE 2 BERBASIS NEEDS ANALYSIS Tiarnida Nababan; Chrismis Novalinda Ginting
Jurnal Maternitas Kebidanan Vol. 7 No. 1 (2022): Jurnal Maternitas Kebidanan
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jumkep.v7i1.2618

Abstract

Although some previous studies have discussed the nursing process for type 2 diabetes mellitus; however, research that specifically discusses adapting the nursing process for type 2 diabetes mellitus through needs analysis has never been studied before. This systematic review aims to review some research publications on nurses' understanding of type 2 diabetes mellitus, the nursing process for patients with type 2 diabetes mellitus, and a needs analysis based type 2 nursing process training model. By using descriptive qualitative research methods, this study uses scientific journal publications in the last ten years as the object of research to describe the condition of nurses' understanding of type 2 diabetes mellitus, the nursing process of type 2 diabetes mellitus patients, and nursing training models based on needs analysis. The results of this systematic review revealed that most of the research journal articles focused on revealing the care of patients with diabetes mellitus by doctors, medical therapy for patients with diabetes mellitus, and comorbidities caused by diabetes mellitus. However, research on nursing training to intensify the implementation of the nursing process for patients with type 2 diabetes mellitus is still very rarely done. By observing this condition, research on the implementation of the nursing process for patients with type 2 diabetes mellitus based on analysis is very necessary to improve the quality of health services for patients with diabetes mellitus.
NARATIVE REVIEW: POTENSI INULIN UMBI DAHLIA SEBAGAI ANTI DIABETES Sunarti Sunarti; Chrismis Novalinda Ginting; Sahna Ferdinand Ginting
Jurnal Keperawatan Priority Vol. 5 No. 1 (2022)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v5i1.2134

Abstract

Inulin is a type of polysaccharide that is commonly found in nature derived from the dahlia tuber plant, and other plants such as chicory, Jerusalem artichoke, Yaco´n potato and asparagus. Inulin is widely used in industry and pharmaceuticals. In the industrial world, inulin is used as a source of natural sweetener, enhances the taste of food, ferments, and is a low-fiber food source. While in the pharmaceutical world, inulin can be used in several studies, one of which is as an anti-diabetic. This study aims to determine the potential of dahlia tuber inulin as an anti-diabetic. The type of research is a narrative review. Search data using three databases, namely Elsevier (SCOPUS), Pubmed and Google Scholar with a limitation of the last 10 years of articles with the keyword "inulin for diabetes", with the PRISMA method. The results showed that inulin works on glucose absorption in the intestine, lowers blood sugar levels, lowers hemoglobin A1c, increases circulating GLP-1, reduces hyperglycemia, reduces insulin resistance (IR) and hyperlipidemia, reduces oxidative stress, increases insulin and leptin levels, facilitates glucose transport of GLUT4 by activating the PI3K/Akt pathway, is anti-inflammatory, and is involved in the expression of several anti-hyperglycemic genes. The conclusion is that dahlia tuber inulin has an anti-diabetic effect.
IGF-1 levels in Patients with Type 2 Diabetes Mellitus Thipani Angela; Chrismis Novalinda Ginting; Linda Chiuman; Sahna Ferdinand Ginting
Majalah Kedokteran Bandung Vol 53, No 2 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v53n2.2278

Abstract

Type 2 Diabetes Mellitus (Type 2 DM) is a metabolic disorder group with mechanisms that include hyperglycemia, insulin resistance and hyperinsulinemia. Type 2 DM has a close association with IGF-1, where the active form of the IGF-1 becomes elevated by reason of the fact that hyperinsulinemia inhibits the production of IGF-binding proteins (IGFBP) 1/IGFBP 2. The active form of IGF-1 has the ability to promote cell proliferation and inhibit apoptosis, hence becomes one of the risk factors for cancer cell growth. This was an analytical study conducted in August at the Harapan Bunda Clinic, Medan, Indonesia to determine the difference between the IGF-1 level and blood glucose level in type 2 DM patients in different age groups. Twenty subjects with Type 2 DM participated in this study and were divided based on their age into 35-50 years old or Group 1 and 51-65 year old group or Group 2. The IGF-1 levels in both groups were compared and analyzed using the T-test dependent method. Results showed that the IGF-1 and blood glucose levels were higher in Group 1 (35-50 years old) when compared to Group 2 and the difference was significant. The change in the IGF-1 level in diabetic patients cannot be determined only by the blood sugar level.
Analysis of Anti-Bacterial Activity of Ethanol Extract Fragrant Pandan Leaves (Pandanus amaryllifolius Roxb) Against the Growth of Disease Cause Pathogen Bacteria Using the Agar Diffusion Method Cut Eliza Hidayani; Chrismis Novalinda Ginting; Linda Chiuman
Budapest International Research in Exact Sciences (BirEx) Journal Vol 3, No 3 (2021): Budapest International Research in Exact Sciences, July
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v3i3.2349

Abstract

Fragrant pandan (Pandanus amaryllifolius Roxb.) is a plant commonly used as fragrance and food coloring. Fragrant pandan contains many substances or bioactive compounds that have medicinal properties so they are also used as traditional medicine. One of the properties of fragrant pandan is as an antimicrobial (antibacterial and antifungal) which is thought to come from the content of alkaloids, flavonoids, phenolics, as well as steroids and terpenoids. This study aims to determine the inhibitory power of fragrant pandan extract (EPW) against the growth of pathogenic bacteria. The test method used is the agar diffusion method by looking at the temperature comparison. Time and Ph.
PENGARUH EKSTRAK KULIT BUAH MANGGIS (Garcinia Mangostana Linn) TERHADAP PERISTALTIK ILEUM TERPISAH MARMOT JANTAN SEBAGAI ANTI DIARE Zaim Anshari; Chrismis Novalinda Ginting; Linda Chiuman; Yuliani Mardiati Lubis
Jurnal Penelitian Farmasi & Herbal Vol 2 No 1 (2019): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v2i1.73

Abstract

Objective: to determine the effect of mangosteen peel extract (Garcinia mangostana Linn) on ileal peristalsis separate male guinea pigs as diarrhea. Results: t-independent test, the difference: Contraction of ileum Acethlcholin with Atropine + Acethylcholin is 6.333 compared to Acethylcholin with extract + Acethylcholin is 8,500 with ANOVA test P value meaning the difference between the two contractions of the ileum is significant. The t-independent test results are the difference: Contraction of ileum Histamine with Diphenhidramine + Histamine is 8.333 compared to Histamine with extract + Histamine is 10.833 with ANOVA test P value meaning the difference between the two contractions of the ileum is significant. The results of the t-independent test are the difference: Contraction of the Barrium ileum with Papaverine + Barrium is 2,500 compared to the contraction of Barrium ileum with extract + Barrium is 2,500 with ANOVA test P value meaning that there is no difference between the two contractions of the ileum. From the three experimental groups, it was concluded that the extract worked similar to Papaverine. Cecilia's study, fruit skin extract can be used as diarrhea in Diare Effect of Mangosteen Ethanol Extract of Oleum ricini-induced Webster Swiss Mice.