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Efektivitas Terapi Antihipertensi Pada Kasus Krisis Hipertensi di Instalasi Gawat Darurat RSUD Ulin Banjarmasin Evita Peron Yoewono; Rina Saputri; Rifa’atul Mahmudah
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 1 (2020): Journal Of Pharmaceutical Care and Science
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.502 KB)

ABSTRACT Background: Hypertension crisis is a case of disease that often occurs, if not handled properly will cause comlication and death. This study was conducted to determine effective therapies in dealing with hypertensive crises so as to minimize the occurrence of complication and death in patients experiencing hypertensive crises Method: The research method is a prospective cohort. Data analysis using Pair T-Test and ANOVA, analytic analysis with evidence based medecine principles. Consists of 11 urgent hypertension samples and 9 emergency hypertension samples. Results: The results of the study for the case of hypertension urgency there are 6 therapeutic groups including furosemide, nicardipine, amlodipine, candesartan + amlodipine, clonidine and furosemide + nicardipine, but the therapy used is not in accordance with the guidelines but there are 2 groups of therapies that can reduce blood pressure including furosemide + nicardipine and clonidine, while for the case of emergence hypertension, there are 5 groups of therapies including nicardipine, amlodipine + nicardipine, furosemide, furosemide + candesartan + amlodipine and furosemide + candesartan + amlodipine + clonidine, the result is that nicardipine is a therapy that is in accordance with the guideline and the therapy is in accordance with the guideline and is in accordance with the guideline therapeutic target in lowering blood pressure. Conclusion: The use therapy is not in accordance with the guidelines for patients with hypertensive urgency cases, but is able to lower the patient’s blood pressure, whereas for patients with hypertensive emergencies the effective therapy is nicardipine. Keywords: Blood Pressure, Effectiveness, Hypertensive Crisis, Urgency Hypertension, Emergency Hypertension.

Aktivitas Antioksidan Dari Infusa Kelakai (Stenochlaena palustris (Burm.F) Bedd) Ali Rakhman Hakim; Amanda Shelvia Savitri; Rina Saputri
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Background: Kelakai (Stenochlaena palustris (Burn. F) Bedd.) Is a plant originating from Kalimantan that grows on peat soil. Objective: to determine the antioxidant activity of the leaves of kelakai (Stenochlaena palustris (Burm. F) Bedd.) made by infusion. Method: This type of research is true experimental and research method with post test only control group design. Kelakai made an infusion and then tested for antioxidant activity using the DPPH method. Results: The kelakai infusion positive contains flavonoids. Kelakai infusion has a very strong antioxidant activity at a concentration of 20 ppm with an absorbance value of 0.072 and an antioxidant activity of 86.90%. Kelakai infusion has an IC50 value of 6.4035 ppm. Conclusion: kelakai infusion positive contains flavonoid compounds and has a very strong antioxidant ability with an IC50 value of 6.4035 ppm. Keywords: antioxidants, flavonoids, infusion, kelakai

Profil Penggunaan Antibiotika di Puskesmas Hantakan dan Profil DAGUSIBU Antibiotika di Desa Hantakan dan Desa Alat Rina Saputri; Ali Rakhman Hakim
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Background : The used of antibiotics in Indonesia continues to increase, but not accompanied by good knowledge regarding the used of these antibiotics so that they have a high risk of causing antibiotic resistance. Objective : Knowing the profile of the use of Antibiotics in Puskesmas Hantakan and knowing the profile of DAGUSIBU antibiotics in Hantakan and Alat Villages. Method : This type of research is descriptive research with survey methods for the last 5 months from October 2020 to February 2021. The survey was also carried out directly to the respondents of the Hantakan Village RT.01 - RT.06 and in Village Alat RT.01 - RT.04. Results : The used of antibiotics at Puskesmas Hantakan is one of the top 10 drugs that are often prescribed. The type of antibiotic that is most widely prescribed is Amoxicillin. DAGUSIBU's profile on respondents shows that the majority of respondents get antibiotics from stalls, use antibiotics to treat various diseases, take antibiotics not according to intervals, stop antibiotics if they feel that conditions have improved, and still keep antibiotics in stock and dispose of antibiotics in an inappropriate way. Conclusion : Amoxicillin is a type of antibiotic that is most widely prescribed in Puskesmas Hantakan. The use of antibiotics without a doctor's prescription in Hantakan and Alat Villages is still high. The proper management of antibiotics among respondents in the Village of Hantakan and Alat was still low.

Pengaruh Edukasi Terhadap Perilaku Penggunaan Obat Tradisional Di Desa Babai Kecamatan Karau Kuala Di Masa Pandemi Covid-19 Gina Aulia Istiqomah; Rina Saputri; Sismeri Dona
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 1 (2021): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

The Effect of Education on Behavioral Using Traditional Medicines in Babai Village, Karau Kuala District During the Covid 19 Pandemic. Supervised by RINA SAPUTRI and SISMERI DONA Background: Inappropriate drug use behavior greatly affects the success of therapy and the emergence of unwanted reactions from treatment. This inaccuracy of public behavior can occur because of the lack of public knowledge about drug information. Efforts to increase knowledge is to provide education. So an educational effort is needed, there are many educational media that can be used, one of which is video. Objective: This study aims to analyze how the influence of education on the behavior of using traditional medicine in Babai Village, Karau Kuala Sub-district during the Covid-19 pandemic. Method: True experimental research with pretest and posttest group design approach. Sampling was done by purposive sampling. The research sample amounted to 100 respondents. The data was obtained by using a questionnaire which was distributed using google form media. Results: Community behavior towards the use of traditional medicine in Babai Village, Karau Kuala sub-district, seen from the pretest results, only 50% of the people behaved positively out of 100 respondents who used traditional medicine. After providing education to the intervention group, there was an improvement in positive behavior of 62.0%. The results of the SPSS analysis with logistic regression test showed a p-value of 0.045 <0.05 which indicated that there was a significant effect on the provision of education. Conclusion: There is an effect of providing education with video media on the behavior of respondents towards the use of traditional medicine in Babai Village, Karau Kuala Sub-district during the covid19 pandemic. Keywords: Behavior, education, video

Determination Of Total Flavonoid Content And Total Phenolic Content Of Pitanak Fruit Skin Extracts (Nephelium sp.) Rina Saputri; Ali Rakhman Hakim
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

The search for the presence of flavonoid and phenolic compounds from plants is still being carried out. This is done because flavonoid and phenolic compounds have high potential as antioxidants. Pitanak fruit is a native fruit of Kalimantan and currently there is no research report on the content of flavonoid and phenolic compounds. This study aims to determine the total flavonoid content and total phenolic content of the pitanak fruit peel extract. This research is a quantitative research with descriptive observational design. The assay used the uv-vis spectrophotometer method. The secondary metabolite compounds contained in the pitanak fruit peel extract are alkaloids, flavonoids, tannins, terpenoids, steroids, and phenolics. Total flavonoid content is 33,183 ppm and total phenolic content is 126,88 ppm. The conclusion of this research is that the pitanak fruit peel extract has total flavonoid and phenolic levels which can be optimized as a source of medicinal raw materials.

E Efektivitas Terapi Antihipertensi Pada Kasus Krisis Hipertensi di Instalasi Gawat Darurat RSUD Ulin Banjarmasin Evita Peron Yoewono; Rina Saputri; Rifaâ€™atul Mahmudah
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 1 (2020): Journal Of Pharmaceutical Care and Science
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar

ABSTRACT Background: Hypertension crisis is a case of disease that often occurs, if not handled properly will cause comlication and death. This study was conducted to determine effective therapies in dealing with hypertensive crises so as to minimize the occurrence of complication and death in patients experiencing hypertensive crises Method: The research method is a prospective cohort. Data analysis using Pair T-Test and ANOVA, analytic analysis with evidence based medecine principles. Consists of 11 urgent hypertension samples and 9 emergency hypertension samples. Results: The results of the study for the case of hypertension urgency there are 6 therapeutic groups including furosemide, nicardipine, amlodipine, candesartan + amlodipine, clonidine and furosemide + nicardipine, but the therapy used is not in accordance with the guidelines but there are 2 groups of therapies that can reduce blood pressure including furosemide + nicardipine and clonidine, while for the case of emergence hypertension, there are 5 groups of therapies including nicardipine, amlodipine + nicardipine, furosemide, furosemide + candesartan + amlodipine and furosemide + candesartan + amlodipine + clonidine, the result is that nicardipine is a therapy that is in accordance with the guideline and the therapy is in accordance with the guideline and is in accordance with the guideline therapeutic target in lowering blood pressure. Conclusion: The use therapy is not in accordance with the guidelines for patients with hypertensive urgency cases, but is able to lower the patientâ€™s blood pressure, whereas for patients with hypertensive emergencies the effective therapy is nicardipine. Keywords: Blood Pressure, Effectiveness, Hypertensive Crisis, Urgency Hypertension, Emergency Hypertension.

A Aktivitas Antioksidan Dari Infusa Kelakai (Stenochlaena palustris (Burm.F) Bedd) Ali Rakhman Hakim; Amanda Shelvia Savitri; Rina Saputri
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.69

Background: Kelakai (Stenochlaena palustris (Burn. F) Bedd.) Is a plant originating from Kalimantan that grows on peat soil. Objective: to determine the antioxidant activity of the leaves of kelakai (Stenochlaena palustris (Burm. F) Bedd.) made by infusion. Method: This type of research is true experimental and research method with post test only control group design. Kelakai made an infusion and then tested for antioxidant activity using the DPPH method. Results: The kelakai infusion positive contains flavonoids. Kelakai infusion has a very strong antioxidant activity at a concentration of 20 ppm with an absorbance value of 0.072 and an antioxidant activity of 86.90%. Kelakai infusion has an IC50 value of 6.4035 ppm. Conclusion: kelakai infusion positive contains flavonoid compounds and has a very strong antioxidant ability with an IC50 value of 6.4035 ppm. Keywords: antioxidants, flavonoids, infusion, kelakai

P Profil Penggunaan Antibiotika di Puskesmas Hantakan dan Profil DAGUSIBU Antibiotika di Desa Hantakan dan Desa Alat Rina Saputri; Ali Rakhman Hakim
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.71

Background : The used of antibiotics in Indonesia continues to increase, but not accompanied by good knowledge regarding the used of these antibiotics so that they have a high risk of causing antibiotic resistance. Objective : Knowing the profile of the use of Antibiotics in Puskesmas Hantakan and knowing the profile of DAGUSIBU antibiotics in Hantakan and Alat Villages. Method : This type of research is descriptive research with survey methods for the last 5 months from October 2020 to February 2021. The survey was also carried out directly to the respondents of the Hantakan Village RT.01 - RT.06 and in Village Alat RT.01 - RT.04. Results : The used of antibiotics at Puskesmas Hantakan is one of the top 10 drugs that are often prescribed. The type of antibiotic that is most widely prescribed is Amoxicillin. DAGUSIBU's profile on respondents shows that the majority of respondents get antibiotics from stalls, use antibiotics to treat various diseases, take antibiotics not according to intervals, stop antibiotics if they feel that conditions have improved, and still keep antibiotics in stock and dispose of antibiotics in an inappropriate way. Conclusion : Amoxicillin is a type of antibiotic that is most widely prescribed in Puskesmas Hantakan. The use of antibiotics without a doctor's prescription in Hantakan and Alat Villages is still high. The proper management of antibiotics among respondents in the Village of Hantakan and Alat was still low.

Pengaruh Edukasi Terhadap Perilaku Penggunaan Obat Tradisional Di Desa Babai Kecamatan Karau Kuala Di Masa Pandemi Covid-19 Gina Aulia Istiqomah; Rina Saputri; Sismeri Dona
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 1 (2021): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.148

The Effect of Education on Behavioral Using Traditional Medicines in Babai Village, Karau Kuala District During the Covid 19 Pandemic. Supervised by RINA SAPUTRI and SISMERI DONA Background: Inappropriate drug use behavior greatly affects the success of therapy and the emergence of unwanted reactions from treatment. This inaccuracy of public behavior can occur because of the lack of public knowledge about drug information. Efforts to increase knowledge is to provide education. So an educational effort is needed, there are many educational media that can be used, one of which is video. Objective: This study aims to analyze how the influence of education on the behavior of using traditional medicine in Babai Village, Karau Kuala Sub-district during the Covid-19 pandemic. Method: True experimental research with pretest and posttest group design approach. Sampling was done by purposive sampling. The research sample amounted to 100 respondents. The data was obtained by using a questionnaire which was distributed using google form media. Results: Community behavior towards the use of traditional medicine in Babai Village, Karau Kuala sub-district, seen from the pretest results, only 50% of the people behaved positively out of 100 respondents who used traditional medicine. After providing education to the intervention group, there was an improvement in positive behavior of 62.0%. The results of the SPSS analysis with logistic regression test showed a p-value of 0.045 <0.05 which indicated that there was a significant effect on the provision of education. Conclusion: There is an effect of providing education with video media on the behavior of respondents towards the use of traditional medicine in Babai Village, Karau Kuala Sub-district during the covid19 pandemic. Keywords: Behavior, education, video

Determination Of Total Flavonoid Content And Total Phenolic Content Of Pitanak Fruit Skin Extracts (Nephelium sp.) Rina Saputri; Ali Rakhman Hakim
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i2.191

The search for the presence of flavonoid and phenolic compounds from plants is still being carried out. This is done because flavonoid and phenolic compounds have high potential as antioxidants. Pitanak fruit is a native fruit of Kalimantan and currently there is no research report on the content of flavonoid and phenolic compounds. This study aims to determine the total flavonoid content and total phenolic content of the pitanak fruit peel extract. This research is a quantitative research with descriptive observational design. The assay used the uv-vis spectrophotometer method. The secondary metabolite compounds contained in the pitanak fruit peel extract are alkaloids, flavonoids, tannins, terpenoids, steroids, and phenolics. Total flavonoid content is 33,183 ppm and total phenolic content is 126,88 ppm. The conclusion of this research is that the pitanak fruit peel extract has total flavonoid and phenolic levels which can be optimized as a source of medicinal raw materials.

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