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Journal : Jurnal Surya Medika

Cost Minimization Analysis (CMA) Penggunaan Obat Captopril dan Lisinopril pada Pasien Hipertensi di RSUD Sultan Suriansyah Banjarmasin: Cost Minimization Analysis (CMA) Use of Captopril and Lisinopril Drugs in Hypertensive Patients at Sultan Suriansyah Hospital Banjarmasin Nailul Muna; Melviani Melviani; Erlina Syamsu
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.4015

Abstract

Hypertension is a world health problem leading to increased morbidity and mortality, as well as burdening the cost of health services, including in Indonesia. Cost Minimal hypertension treatment can reduce the high incidence of hypertension. The purpose of this study was to determine the cost that is more cost-minimize among the use of captopril and lisinopril in outpatient hypertension patients at Sultan Suriansyah Hospital Banjarmasin. This study is an analytic with a design cross sectional. Data collection is done by looking at the medical records of hypertensive patients outpatient hospital Sultan Suriansyah Banjarmasin who received antihypertensive therapy captopril and lisinopril. The sampling method used is non-probability sampling by using the technique purposive non-random sampling. Samples that 35 patients were used. The cost component measured is direct medical costs outpatient hypertensive patients which includes the cost of antihypertensive drugs, the cost of disease drugs participants, laboratory fees, and consulting fees. The results showed that the average total direct medical cost in the captopril group was Rp127.886 and the group lisinopril Rp.274.971. In the captopril group it has a more minimal cost compared with the lisinopril group.
Aktivitas Antibakteri dan Penetapan Kadar Flavonoid Fraksi Daun Kalangkala (Litsea angulata) Serta Profil Kromatografi Lapis Tipis: Antibacterial Activity and Determination of Flavonoid Levels of Kalangkala Leaf Fraction (Litsea angulata) and Thin Layer Chromatography Profile Rohama Rohama; Melviani Melviani; Rahmadani Rahmadani
Jurnal Surya Medika (JSM) Vol. 9 No. 1 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i1.5194

Abstract

Traditionally the people of Kalimantan use kalangkala (Litsea angulata) to treat various diseases, one of which is diarrhea. It is known that kalangkala contains flavonoids that have antibacterial activity. Kalangkala leaf extract was tested for antibacterial activity against Escherichia coli which is one of the bacteria that causes diarrhea by diffusion and dilution. Then flavonoid levels are determined by the Spectophotometry UV-Vis method and see how thin layer chromatography profiles at the fraction level to find out how much flavonoid compounds there are. The results showed that kalangkala leaf extract has antibacterial activity against E.coli by diffusion obtained the diameter of the inhibitory zone already visible at a concentration of 20 mg / ml. Dilutionally obtained the value of KHM at a concentration of 50% and KBM at a concentration of 100%. Flavonoid levels in the extract were 71,367 mg QE(Quercetin Equialen)/g, at the n-Hexane fraction of 8,367 mg QE(Quercetin Equialen)/g, at the ethyl acetate fraction of 6,700 mg QE(Quercetin Equialen)/g and at the aquadest fraction of 5,700 mg QE(Quercetin Equialen)/g. Profile of Thin-Layered Chromatogaphy of the n-Hexane fraction with n-Hexane : Ethyl Acetate (8:12) eluene appeared 7 stains, ethyl acetate fraction with ethyl acetate : N-Hexane (3:7) eluene appears 5 stains and aquadest fraction with butanol: acetic acid : aquadest (4:1:5) eluent appears 2 stains.