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All Journal Jurnal Pengabdian UntukMu NegeRI JOPS (Journal Of Pharmacy and Science) JURNAL PHOTON Prosiding Seminar Nasional: Pertemuan Ilmiah Tahunan Politeknik Kesehatan Karya Husada Yogyakarta JPK: Jurnal Proteksi Kesehatan Reswara: Jurnal Pengabdian Kepada Masyarakat Indonesia Berdaya Jurnal Farmanesia Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Jurnal Ilmiah Kesehatan Masyarakat International Journal of Health Science and Technology DEVOTE: Jurnal Pengabdian Masyarakat Global JFARM (Jurnal Farmasi) Borneo Journal of Pharmacy

Wahyu Margi Sidoretno

Fakultas Farmasi Dan Ilmu Kesehatan, Universitas Abdurrab

Author-ID : 2712801

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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KANDUNGAN VITAMIN A PADA BUAH PEPAYA HIJAU: SOLUSI MENINGKATKAN PRODUKSI ASI Dewi Sartika Siagian; Sara Herlina; Wahyu Margi Sidoretno
Prosiding Seminar Nasional: Pertemuan Ilmiah Tahunan Politeknik Kesehatan Karya Husada Yogyakarta Vol 1 No 1 (2019): Prosiding Seminar Nasional Poltekkes Karya Husada Yogyakarta Tahun 2019
Publisher : Prosiding Seminar Nasional: Pertemuan Ilmiah Tahunan Politeknik Kesehatan Karya Husada Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (216.068 KB)

Pepaya (Carica papaya Linnaeus) merupakan jenis tanaman perdu yang mempunyai tinggi 2-10 meter. Pepaya juga termasuk jenis tanaman tropis basah yang mampu tumbuh subur di daerah yang memiliki ketinggian 0 m - 1500 m di atas permukaan laut. Selain itu, tanaman pepaya juga memiliki kandungan yang sangat bermanfaat bagi manusia. Kandungan per 100 gram buah dan daun pepaya mengandung gizi yang sangat baik untuk kesehatan. Salah satu manfaat buah pepaya yaitu daunnya dapat dimanfaatkan untuk lalapan, menambah nafsu makan, sumber vitamin A sayuran, buah, bahan manisan, puree, campuran saus tomat, pasta, dan juice gangguan lambung, sariawan, kekurangan ASI (buah mentah/pepaya hijau). Tujuan penelitian ini yaitu mengetahui kandungan vitamin A pada buah papaya hijau untuk meningkatkan produksi ASI. Jenis penelitian ini adalah eksperimen yang dilaksanakan dilaboratorium Universitas Riau untuk mengetahui kandungan vitamin A yang terdapat pada buah pepaya hijau. Metode pemeriksaan buah pepaya menggunakan teknik High Performance Liquid Charomatography (HPL). Hasil penelitian terdapat 0,7065 mg Vitamin A dalam 1 gram buah pepaya hijau.

UJI AKTIVITAS ANTIOKSIDAN SEDIAAN GEL YANG MENGANDUNG EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J. R & G. Forst) DENGAN MENGGUNAKAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazyl) Wahyu Margi Sidoretno; Rosa Devitria; Harni Sepriyani
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Matoa (Pometia pinnata J.R & J. G. Forster) is one of the plants that can be used for traditional medicine. Based on several studies, it is stated that the ethanolic extract of matoa leaves has good antioxidant activity. This study aims to determine the antioxidant activity of gel preparations from the ethanolic extract of matoa (Pometia pinnata) leaves. Matoa leaf extract (Pometia pinnata) was prepared using maceration method with 96% ethanol as solvent. Then the extract was formulated into a gel with 4 formulations, namely F0 (no matoa leaf extract), FI (with 0.1% matoa leaf ethanol extract), FII (with 0.3% matoa leaf extract), FIII (with ethanol leaf matoa by 0.5%). Furthermore, the antioxidant activity test was carried out on the gel samples using the DPPH method (1,1-diphenyl-2-picrylhydrazyl) spectrophotometrically at a wavelength of 515 nm. The results of the antioxidant activity test showed that the percentage of inhibition of the 96% ethanol extract of matoa leaf (Pometia pinnata) was F0 40.34%, FI 55.187%, FII 61.703%, FIII 27.969%, and the percentage inhibition of vitamin C was 178.947%. So it can be said that the matoa leaf extract gel has antioxidant activity.

Potential of the Ethanolic Extract of Matoa Leaves (Pometia pinnata J.R. & G.Forst) against Staphylococcus aureus bacteria Wahyu Margi Sidoretno
JURNAL PROTEKSI KESEHATAN Vol 10 No 2 (2021): JPK: Jurnal Proteksi Kesehatan
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v10i2.402

Staphylococcus aureus is a bacterium that can cause several diseases in humans such as ulcers and wound infections. Matoa leaves contain phenolic and flavonoid compounds which are known to have antibacterial properties. The purpose of this study was to determine the antibacterial activity of the ethanolic extract of Pometia pinnata J.R. & G.Forst leaves against Staphylococcus aureus at concentrations of 10%, 20%, and 30%. This research was conducted by disc diffusion method on Mueller Hinton Agar (MHA) media. Antibacterial activity was measured by looking at the inhibition of the growth of S. aureus bacteria. Based on the results of the study, it was found that the ethanolic extract of matoa leaves was able to inhibit the growth of S. aureu bacteria with the average inhibition zones produced at concentrations of 10%, 20% and 30%, namely 11.06 mm, 15.07 mm, 16.07 mm and control ciprofloxacin positive was 28.10 mm. From the results above, it can be concluded that the ethanolic extract of matoa (Pometia pinnata) leaves has antibacterial activity against Staphylococcus aureus.

IDENTIFIKASI FORMALIN PADA KUNYIT GILING DI PASAR PANAM KOTA PEKANBARU MENGGUNAKAN PEREAKSI SCHIFF Denia Pratiwi; Wahyu Margi Sidoretno
JURNAL FARMASI DAN MAKANAN Vol 2 No 1 (2018): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar

Formalin or commonly referred to as formaldehyde is a clear liquid, colorless or almost colorless, piercing smell, steam stimulates the mucous membrane of the nose and throat. The use of formalin as a food preservative is prohibited in the Regulation of the Minister of Health of the Republic of Indonesia Number 033 of 2012, because formalin is toxic (poison). This study identified formalin content in ground turmeric using Schiff reagent. The sample used is ground turmeric which is produced in the market at Panam, Pekanbaru. The purpose of this study was to determine whether milled turmeric produced at the Panam Market in Pekanbaru city contained formaldehyde. This method research qualitative analysis and was conducted at the Anafarma Laboratory of Abdurrab University in January 2017. From the results of the research that has been done, it was obtained from 10 test samples, 3 of which were positive formalin.

AKTIVITAS ANTIOKSIDAN Fraksi n-hexan, Kloroform dan etil asetat DAUN MATOA (Pometia pinnata J.R & G. Forst) TERHADAP DPPH (2,2-difenil-1-pikrilhidrazil) Wahyu Margi Sidoretno; Iis Sintiyani
JURNAL FARMASI DAN MAKANAN Vol 2 No 1 (2018): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v2i1.1260

Antioksidan adalah senyawa yang dapat menetralkan radikal bebas dengan cara menerima atau mendonorkan satu elektron untuk menghilangkan kondisi “elektron tidak berpasangan pada radikal bebas”. Diketahui daun matoa mengandung kelompok senyawa berupa flavanoid, tanin dan saponin. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antioksidan ekstrak daun matoa (Pometia pinnata J.R & G. Forst) terhadap DPPH (2,2- difenil-1-pikrilhidrazil) pada fraksi n-heksan, klorofom dan etil asetat. Pengujian dilakukan pada panjang gelombang 520 nm digunakan microplate reader. Uji aktivitas antioksidan fraksi n-heksan dan klorofom menggunakan konsentrasi 1000 µg/ml, 500 µg/ml, 250 µg/ml, 125 µg/ml, 62,5 µg/ml dan 31.25 µg/ml. Aktivitas antioksidan pada fraksi n-heksan memiliki aktivitas antioksidan sangat lemah dengan IC50 yaitu 312,1238 µg/ml dan fraksi klorofom memiliki aktivitas antioksidan sedang dengan IC50 yaitu 100,9470 µg/ml. Aktivitas antioksidan dengan katagori sangat kuat di tunjukkan oleh fraksi etil asetat dengan konsentrasi 100 µg/ml, 50 µg/ml, 25 µg/ml, 12,5 µg/ml, 6,25 µg/ml dan 3,125 µg/ml dengan didapatkan nilai IC50 yaitu 12, 1876 µg/ml.

KARAKTERISASI SIFAT FISIKOKIMIA SISTEM DISPERSI PADAT NIMODIPIN DENGAN POLOXAMER 188 MENGGUNAKAN METODE PENGGILINGAN BERSAMA Henni Rosaini; Yolla Erman Novita Sari; Indra Makmur; Auzal Halim; Wahyu Margi Sidoretno
JURNAL FARMASI DAN MAKANAN Vol 3 No 2 (2020): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v4i2.1351

Nimodipin merupakan salah satu senyawa yang tidak larut dalam air dan termasuk ke dalam Biopharmaceutical Classification System (BCS) kelas II. Sistem dispersi padat adalah campuran yang homogen dari satu atau lebih bahan aktif dalam matriks yang inert dengan tujuan meningkatkan bioavaibilitas dari bahan obat yang sukar larut. Penelitian ini bertujuan untuk melihat pengaruh penambahan poloxamer 188 terhadap sifat fisikokimia dan profil disolusi dari nimodipin yang dibuat dengan metode penggilingan bersama. Perbandingan nimodipin dengan poloxamer 188 untuk F1, F2, F3 berturut – turut adalah 1:9, 2:8, dan 3:7 (b/b). Karakterisasi campuran fisik dan dispersi padat meliputi distribusi ukuran partikel, XRD, FT-IR, DSC, penetapan kadar dan laju disolusi. Hasil penelitian menunjukan bahwa sifat fisikokimia dari setiap formula sudah berbentuk amorf dan nimodipin terdispersi ke dalam matriks polimer. Laju disolusi dari formula meningkat dibandingkan zat murni dan campuran fisik. Laju disolusi paling tinggi ditunjukkan pada F1, dimana pada waktu 60 menit persentase terdisolusinya sebesar 90,5920 %. Analisa statistik efisiensi disolusi menunjukkan perbedaan yang bermakna (sig<0,005) antara semua formula.

Aktivitas Antijamur Ekstrak Etanol Daun Matoa (Pometia Pinnata J.R. & G.Forst) Terhadap Pertumbuhan Jamur Trichophyton Mentagrophytes Wahyu Margi Sidoretno; Mirna Gustari
Sistem Informasi Vol 11 No 2 (2021): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v11i2.2705

The matoa plant is widely used to treat infectious diseases caused by bacteria and fungi. The purpose of this study was to determine the antifungal activity of the ethanolic extract of matoa (Pometia pinnata) leaves on the growth of Trichophyton mentagrophytes at various concentrations 10%, 20%, and 30%. Trichophyton mentagrophytes are a type of fungus that belongs to the dermatophyte group that causes dermatophytoses (ringworm). The experimental laboratory methods were used in this study. The antifungal activity was determined by using the agar diffusion method. Ketoconazole was used as the positive control, and DMSO was used as the negative control. This study showed the inhibition zone of the extract with concentrations 10%, 20%, 30% were 23.05 mm, 24.86 mm, 25.05 mm, respectively. Ketoconazole as positive control showed the inhibition zone 28.56 mm. From the results, it can be concluded that the ethanolic extract of the leaves of matoa (Pometia pinnata) has potential antifungal activity against Trichophyton mentagrophytes.

Uji Efektivitas Antibakteri Ekstrak Metanol Daun Bandotan (Ageratum conyzoides L.) Terhadap Staphylococcus Aureus Lovera Anggraini; Wahyu Margi Sidoretno; Liza Salsabila Rifwan Putri
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 1 No. 1 (2022): Januari 2022
Publisher : Yayasan Literasi Sains Indonesia

Bandotan (Ageratum conyzoides L.) is a wild plant that is better known as a nuisance plant (weed) in gardens and fields. Bandotan (Ageratum conyzoides L.) has traditional properties, namely to treat infectious diseases of the skin such as boils and wounds caused by bacteria. Staphylococcus aureus is a Gram positive bacterium which is a normal flora in humans and can be pathogenic that causes infection. This study aims to determine the antibacterial activity of the methanolic extract of bandotan (Ageratum conyzoides L.) against the growth of Staphylococcus aureus at concentrations of 10%, 20% and 30%. This research is a laboratory experimental study to determine the diameter of antibacterial inhibition. The method used to test the antibacterial activity in this study was the agar diffusion method and chloramphenicol as a positif control. Extraction method is done by maceration method using methanol solvent. The results of the inhibition test with extract concentrations of 10%, 20% and 30% could inhibit the growth of Staphylococcus aureus with the average diameter of the inhibition zones being 7,3 mm, 8,1 mm, 8,9 mm and the positive control chloramphenicol was 29,3 mm. From the results above, it can be concluded that the methanolic extract of Bandotan leaves (Ageratum conyzoides L.) has antibacterial activity against Staphylococcus aureus.

Pemanfaatan Tepung Tulang Ikan Patin Sebagai Bahan Fortifikasi Biskuit untuk Stunting di Kabupaten Rokan Hilir Dewi Sartika Siagian; Nurmaliza Nurmaliza; Siti Qomariah; Wiwi Sartika; Sara Herlina; Wahyu Margi Sidoretno; Nova Relida; Adelina Maryanti
Indonesia Berdaya Vol 3, No 3: May-July 2022
Publisher : Utan Kayu Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.2022243

Rokan Hilir is a district with the 4th rank out of 5 districts/cities in Riau related to stunting problems.One of the causes of stunting is inadequate intake of energy and nutrients. Foods that contain calcium and protein are found in fish. Rokan downstream is a city of fish. Fish bones and skulls can be processed into flour because this part of the fish still contains minerals, such as calcium in fish bone meal, which can be utilized. The purpose of this service is to increase the knowledge and skills of mothers in utilizing catfish bone waste to be used as biscuits in overcoming stunting. This activity was carried out in the village of Labuhan Tangga downstream with 15 participants. The methods used are lectures, questions and answers, training on making catfish bone meal and biscuit making. The results of this community activity can be seen an increase in participants' knowledge about stunting seen from the pretest and posttest scores from 47.3 to 85.0. The result of the training is that the participants have succeeded in making catfish bone meal and biscuits. It is hoped that the people of the village of Labuhan Tangga downstream can take advantage of local fish products and processing the fish into biscuits can also be used as a source of business or a side business for the family. Abstrak: Rokan Hilir merupakan kabupaten dengan peringkat ke 4 dari 5 kabupaten/kota di Riau terkait masalah stunting. Salah satu penyebab stunting adalah tidak memadai asupan energi dan zat gizi. Makanan yang mengandung kalsium dan protein terdapat pada ikan. Rokan hilir merupakan kota ikan, Tulang dan tengkorak ikan dapat diproses menjadi tepung karena bagian ikan ini masih terdapat kandungan mineral, seperti kalsium pada tepung tulang ikan yang dapat dimanfaatkan. Tujuan pengabdian ini adalah untuk menambah pengetahuan dan keterampilan ibu dalam memanfaatkan limbah tulang ikan patin untuk dijadikan biskuit dalam mengatasi stunting. Kegiatan ini dilakukan di desa labuhan tangga hilir dengan jumlah peserta 15 orang. Metode yang dilakukan yaitu ceramah, tanya jawab, pelatihan pembuatan tepung tulang ikan patin dan pembuatan biskuit. Hasil dari kegiatan masyarakat ini dapat diketahui adanya peningkatan pengetahuan peserta tentang stunting dilihat dari nilai pretest dan postest yaitu 47,3 menjadi 85,0. Hasil pelatihan yaitu para peserta telah berhasil membuat tepung tulang ikan patin dan biskuit. Diharapkan kepada masyarakat desa labuhan tangga hilir dapat memanfaatkan produk ikan lokal dan pengolahan ikan tersebut menjadi biskuit juga dapat dijadikan sebagai sumber usaha atau usaha sampingan bagi keluarga

Microbiological Analysis On Bone Flour Patin Fish (Pangasius Hypophthalmus Sp.) Biscuit Is Rich In Calcium For Children Dewi Sartika Siagian; Wahyu Margi Sidoretno; Sri Kartini
International Journal of Health Science and Technology Vol 3, No 1 (2021): July
Publisher : Universitas 'Aisyiyah Yogyakarta

Ikan Patin bones are a by-product of the fish processing industry which contains the most calcium from the fish body because the main elements of fish bones are calcium, phosphorus and carbonate. Biscuits are snack that have a water quality standard of less than 5% so that they have a crunchy texture. The purpose of this study was to see microbial contamination in biscuits using the ALT (Total Plate Number) method. The results of microbial contamination meet the specified requirements and are included in the category of safe and normal standards according to SNI 2973:2011.

Co-Authors Ade Febriani Adelina Maryanti Aisyah Fadhiyah Zaroh Alya Rosa Asiska Permata Dewi Aulia Sekar Andini Auzal Halim Brilian Dini Ma. Iballa Debi Setiawan Denia Pratiwi Dewi Sartika Siagian Dewi Sartika Siagian Dewi Sartika Siagian Dirga Prasetyo Elma Fitri Handayani Erick Caesarrani Faiza Furqoningsih Fauzana, Annisa Fitria Wulandari Harni Sepriyani Herlina, Sara Iis Sintiyani Indra Makmur Isna Wardaniati Isna Wardianati Liza Salsabila Rifwan Putri Lovera Anggraini Maya Maimuna Mirna Gustari Muhammad Arif Muhammad Zamri Nabila Anil Hawa Nadira Putri Nadya Wulandari Nova Relida Novi Dini Restia Novi Elvira Nur Aisah Nurmaliza Nurmaliza Nurul Husna Santila Putri Marliani Putri Zalfa Azura Rahmadhani Chan Ramadri Saputra Ramalia Noratama Resti Viviasiska Putri Rhoma Saputra Rini Lestari Rosa Devitria Rosaini, Henni Sellia Juwita Sevyna Aulia Rizky Silvia Indriani Siti Aisyah Siti Hajar Siti Qomariah Sri Kartini Sri Zerita Azlin Suci Ramadani Suci Shinta Lestari Syafandi Dio Ramadani Vivi Vazelah Widia Puji Angraini Windi Wulandari Wisnuhadi Bagaskara Wiwi Sartika Yohana Partician Nainggolan Yolla Erman Novita Sari Yudhis Thira Yuharika Pratiwi Zaharatul Aini

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