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KANDUNGAN VITAMIN A PADA BUAH PEPAYA HIJAU: SOLUSI MENINGKATKAN PRODUKSI ASI Dewi Sartika Siagian; Sara Herlina; Wahyu Margi Sidoretno
Prosiding Seminar Nasional: Pertemuan Ilmiah Tahunan Politeknik Kesehatan Karya Husada Yogyakarta Vol 1 No 1 (2019): Prosiding Seminar Nasional Poltekkes Karya Husada Yogyakarta Tahun 2019
Publisher : Prosiding Seminar Nasional: Pertemuan Ilmiah Tahunan Politeknik Kesehatan Karya Husada Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (216.068 KB)

Abstract

Pepaya (Carica papaya Linnaeus) merupakan jenis tanaman perdu yang mempunyai tinggi 2-10 meter. Pepaya juga termasuk jenis tanaman tropis basah yang mampu tumbuh subur di daerah yang memiliki ketinggian 0 m - 1500 m di atas permukaan laut. Selain itu, tanaman pepaya juga memiliki kandungan yang sangat bermanfaat bagi manusia. Kandungan per 100 gram buah dan daun pepaya mengandung gizi yang sangat baik untuk kesehatan. Salah satu manfaat buah pepaya yaitu daunnya dapat dimanfaatkan untuk lalapan, menambah nafsu makan, sumber vitamin A sayuran, buah, bahan manisan, puree, campuran saus tomat, pasta, dan juice gangguan lambung, sariawan, kekurangan ASI (buah mentah/pepaya hijau). Tujuan penelitian ini yaitu mengetahui kandungan vitamin A pada buah papaya hijau untuk meningkatkan produksi ASI. Jenis penelitian ini adalah eksperimen yang dilaksanakan dilaboratorium Universitas Riau untuk mengetahui kandungan vitamin A yang terdapat pada buah pepaya hijau. Metode pemeriksaan buah pepaya menggunakan teknik High Performance Liquid Charomatography (HPL). Hasil penelitian terdapat 0,7065 mg Vitamin A dalam 1 gram buah pepaya hijau.
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN GEL YANG MENGANDUNG EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J. R & G. Forst) DENGAN MENGGUNAKAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazyl) Wahyu Margi Sidoretno; Rosa Devitria; Harni Sepriyani
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.368 KB) | DOI: 10.51544/jf.v8i2.2796

Abstract

Matoa (Pometia pinnata J.R & J. G. Forster) is one of the plants that can be used for traditional medicine. Based on several studies, it is stated that the ethanolic extract of matoa leaves has good antioxidant activity. This study aims to determine the antioxidant activity of gel preparations from the ethanolic extract of matoa (Pometia pinnata) leaves. Matoa leaf extract (Pometia pinnata) was prepared using maceration method with 96% ethanol as solvent. Then the extract was formulated into a gel with 4 formulations, namely F0 (no matoa leaf extract), FI (with 0.1% matoa leaf ethanol extract), FII (with 0.3% matoa leaf extract), FIII (with ethanol leaf matoa by 0.5%). Furthermore, the antioxidant activity test was carried out on the gel samples using the DPPH method (1,1-diphenyl-2-picrylhydrazyl) spectrophotometrically at a wavelength of 515 nm. The results of the antioxidant activity test showed that the percentage of inhibition of the 96% ethanol extract of matoa leaf (Pometia pinnata) was F0 40.34%, FI 55.187%, FII 61.703%, FIII 27.969%, and the percentage inhibition of vitamin C was 178.947%. So it can be said that the matoa leaf extract gel has antioxidant activity.
Potential of the Ethanolic Extract of Matoa Leaves (Pometia pinnata J.R. & G.Forst) against Staphylococcus aureus bacteria Wahyu Margi Sidoretno
JURNAL PROTEKSI KESEHATAN Vol 10 No 2 (2021): JPK: Jurnal Proteksi Kesehatan
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v10i2.402

Abstract

Staphylococcus aureus is a bacterium that can cause several diseases in humans such as ulcers and wound infections. Matoa leaves contain phenolic and flavonoid compounds which are known to have antibacterial properties. The purpose of this study was to determine the antibacterial activity of the ethanolic extract of Pometia pinnata J.R. & G.Forst leaves against Staphylococcus aureus at concentrations of 10%, 20%, and 30%. This research was conducted by disc diffusion method on Mueller Hinton Agar (MHA) media. Antibacterial activity was measured by looking at the inhibition of the growth of S. aureus bacteria. Based on the results of the study, it was found that the ethanolic extract of matoa leaves was able to inhibit the growth of S. aureu bacteria with the average inhibition zones produced at concentrations of 10%, 20% and 30%, namely 11.06 mm, 15.07 mm, 16.07 mm and control ciprofloxacin positive was 28.10 mm. From the results above, it can be concluded that the ethanolic extract of matoa (Pometia pinnata) leaves has antibacterial activity against Staphylococcus aureus.
IDENTIFIKASI FORMALIN PADA KUNYIT GILING DI PASAR PANAM KOTA PEKANBARU MENGGUNAKAN PEREAKSI SCHIFF Denia Pratiwi; Wahyu Margi Sidoretno
JURNAL FARMASI DAN MAKANAN Vol 2 No 1 (2018): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

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Abstract

Formalin or commonly referred to as formaldehyde is a clear liquid, colorless or almost colorless, piercing smell, steam stimulates the mucous membrane of the nose and throat. The use of formalin as a food preservative is prohibited in the Regulation of the Minister of Health of the Republic of Indonesia Number 033 of 2012, because formalin is toxic (poison). This study identified formalin content in ground turmeric using Schiff reagent. The sample used is ground turmeric which is produced in the market at Panam, Pekanbaru. The purpose of this study was to determine whether milled turmeric produced at the Panam Market in Pekanbaru city contained formaldehyde. This method research qualitative analysis and was conducted at the Anafarma Laboratory of Abdurrab University in January 2017. From the results of the research that has been done, it was obtained from 10 test samples, 3 of which were positive formalin.
AKTIVITAS ANTIOKSIDAN Fraksi n-hexan, Kloroform dan etil asetat DAUN MATOA (Pometia pinnata J.R & G. Forst) TERHADAP DPPH (2,2-difenil-1-pikrilhidrazil) Wahyu Margi Sidoretno; Iis Sintiyani
JURNAL FARMASI DAN MAKANAN Vol 2 No 1 (2018): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v2i1.1260

Abstract

Antioksidan adalah senyawa yang dapat menetralkan radikal bebas dengan cara menerima atau mendonorkan satu elektron untuk menghilangkan kondisi “elektron tidak berpasangan pada radikal bebas”. Diketahui daun matoa mengandung kelompok senyawa berupa flavanoid, tanin dan saponin. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antioksidan ekstrak daun matoa (Pometia pinnata J.R & G. Forst) terhadap DPPH (2,2- difenil-1-pikrilhidrazil) pada fraksi n-heksan, klorofom dan etil asetat. Pengujian dilakukan pada panjang gelombang 520 nm digunakan microplate reader. Uji aktivitas antioksidan fraksi n-heksan dan klorofom menggunakan konsentrasi 1000 µg/ml, 500 µg/ml, 250 µg/ml, 125 µg/ml, 62,5 µg/ml dan 31.25 µg/ml. Aktivitas antioksidan pada fraksi n-heksan memiliki aktivitas antioksidan sangat lemah dengan IC50 yaitu 312,1238 µg/ml dan fraksi klorofom memiliki aktivitas antioksidan sedang dengan IC50 yaitu 100,9470 µg/ml. Aktivitas antioksidan dengan katagori sangat kuat di tunjukkan oleh fraksi etil asetat dengan konsentrasi 100 µg/ml, 50 µg/ml, 25 µg/ml, 12,5 µg/ml, 6,25 µg/ml dan 3,125 µg/ml dengan didapatkan nilai IC50 yaitu 12, 1876 µg/ml.
KARAKTERISASI SIFAT FISIKOKIMIA SISTEM DISPERSI PADAT NIMODIPIN DENGAN POLOXAMER 188 MENGGUNAKAN METODE PENGGILINGAN BERSAMA Henni Rosaini; Yolla Erman Novita Sari; Indra Makmur; Auzal Halim; Wahyu Margi Sidoretno
JURNAL FARMASI DAN MAKANAN Vol 3 No 2 (2020): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v4i2.1351

Abstract

Nimodipin merupakan salah satu senyawa yang tidak larut dalam air dan termasuk ke dalam Biopharmaceutical Classification System (BCS) kelas II. Sistem dispersi padat adalah campuran yang homogen dari satu atau lebih bahan aktif dalam matriks yang inert dengan tujuan meningkatkan bioavaibilitas dari bahan obat yang sukar larut. Penelitian ini bertujuan untuk melihat pengaruh penambahan poloxamer 188 terhadap sifat fisikokimia dan profil disolusi dari nimodipin yang dibuat dengan metode penggilingan bersama. Perbandingan nimodipin dengan poloxamer 188 untuk F1, F2, F3 berturut – turut adalah 1:9, 2:8, dan 3:7 (b/b). Karakterisasi campuran fisik dan dispersi padat meliputi distribusi ukuran partikel, XRD, FT-IR, DSC, penetapan kadar dan laju disolusi. Hasil penelitian menunjukan bahwa sifat fisikokimia dari setiap formula sudah berbentuk amorf dan nimodipin terdispersi ke dalam matriks polimer. Laju disolusi dari formula meningkat dibandingkan zat murni dan campuran fisik. Laju disolusi paling tinggi ditunjukkan pada F1, dimana pada waktu 60 menit persentase terdisolusinya sebesar 90,5920 %. Analisa statistik efisiensi disolusi menunjukkan perbedaan yang bermakna (sig<0,005) antara semua formula.
Aktivitas Antijamur Ekstrak Etanol Daun Matoa (Pometia Pinnata J.R. & G.Forst) Terhadap Pertumbuhan Jamur Trichophyton Mentagrophytes Wahyu Margi Sidoretno; Mirna Gustari
Sistem Informasi Vol 11 No 2 (2021): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v11i2.2705

Abstract

The matoa plant is widely used to treat infectious diseases caused by bacteria and fungi. The purpose of this study was to determine the antifungal activity of the ethanolic extract of matoa (Pometia pinnata) leaves on the growth of Trichophyton mentagrophytes at various concentrations 10%, 20%, and 30%. Trichophyton mentagrophytes are a type of fungus that belongs to the dermatophyte group that causes dermatophytoses (ringworm). The experimental laboratory methods were used in this study. The antifungal activity was determined by using the agar diffusion method. Ketoconazole was used as the positive control, and DMSO was used as the negative control. This study showed the inhibition zone of the extract with concentrations 10%, 20%, 30% were 23.05 mm, 24.86 mm, 25.05 mm, respectively. Ketoconazole as positive control showed the inhibition zone 28.56 mm. From the results, it can be concluded that the ethanolic extract of the leaves of matoa (Pometia pinnata) has potential antifungal activity against Trichophyton mentagrophytes.
Uji Efektivitas Antibakteri Ekstrak Metanol Daun Bandotan (Ageratum conyzoides L.) Terhadap Staphylococcus Aureus Lovera Anggraini; Wahyu Margi Sidoretno; Liza Salsabila Rifwan Putri
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 1 No. 1 (2022): Januari 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (338.398 KB) | DOI: 10.55123/sehatmas.v1i1.15

Abstract

Bandotan (Ageratum conyzoides L.) is a wild plant that is better known as a nuisance plant (weed) in gardens and fields. Bandotan (Ageratum conyzoides L.) has traditional properties, namely to treat infectious diseases of the skin such as boils and wounds caused by bacteria. Staphylococcus aureus is a Gram positive bacterium which is a normal flora in humans and can be pathogenic that causes infection. This study aims to determine the antibacterial activity of the methanolic extract of bandotan (Ageratum conyzoides L.) against the growth of Staphylococcus aureus at concentrations of 10%, 20% and 30%. This research is a laboratory experimental study to determine the diameter of antibacterial inhibition. The method used to test the antibacterial activity in this study was the agar diffusion method and chloramphenicol as a positif control. Extraction method is done by maceration method using methanol solvent. The results of the inhibition test with extract concentrations of 10%, 20% and 30% could inhibit the growth of Staphylococcus aureus with the average diameter of the inhibition zones being 7,3 mm, 8,1 mm, 8,9 mm and the positive control chloramphenicol was 29,3 mm. From the results above, it can be concluded that the methanolic extract of Bandotan leaves (Ageratum conyzoides L.) has antibacterial activity against Staphylococcus aureus.
Microbiological Analysis On Bone Flour Patin Fish (Pangasius Hypophthalmus Sp.) Biscuit Is Rich In Calcium For Children Dewi Sartika Siagian; Wahyu Margi Sidoretno; Sri Kartini
International Journal of Health Science and Technology Vol 3, No 1 (2021): July
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (207.081 KB) | DOI: 10.31101/ijhst.v3i1.2168

Abstract

Ikan Patin bones are a by-product of the fish processing industry which contains the most calcium from the fish body because the main elements of fish bones are calcium, phosphorus and carbonate. Biscuits are snack that have a water quality standard of less than 5% so that they have a crunchy texture. The purpose of this study was to see microbial contamination in biscuits using the ALT (Total Plate Number) method. The results of microbial contamination meet the specified requirements and are included in the category of safe and normal standards according to SNI 2973:2011.
Sosialisasi Tanaman Toga Pelancar Asi Di Daerah Limbungan RW 08 Kelurahan Rumbai Pesisir Kota Pekanbaru Ade Febriani; Erick Caesarrani; Novi Elvira; Sellia Juwita; Wahyu Margi Sidoretno; Siti Aisyah
Jurnal Pengabdian UntukMu NegeRI Vol 6 No 2 (2022): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v6i2.3969

Abstract

This community service activity program is so that mothers, especially breastfeeding mothers, can know the types and benefits of the toga plant to facilitate breastfeeding. This community service is carried out in the form of counseling and implementation of the introduction of special toga plants to facilitate breastfeeding for breastfeeding mothers directly and planting toga plants in the area around the mother's house (respondents). Community service consists of 2 stages, the first stage is collecting data on breastfeeding mothers and planting toga seedlings and the second stage is the distribution of seeds which will be carried out during the posyandu schedule in the Limbungan RW 08 Kelurahan Rumbai Pesisir, namely on June 08 2022. the result of this community service activity is a good response from the respondents. Participants are able and have been able to do processing and understand about the toga plant to facilitate the production of breast milk. During the activity, it was found that the mother's knowledge about the toga plant to increase breast milk was good and all the audience understood about the toga plant to increase breast milk.