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All Journal International Journal of Public Health Science (IJPHS) Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jurnal Ilmiah Farmasi Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Farmasi Klinik Indonesia Jurnal Farmasi Sains dan Komunitas (JFSK) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Farmaseutik JFIOnline JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Kefarmasian AKFARINDO Jurnal Farmagazine Journal of Holistics and Health Sciences (JHHS) Jurnal Sains dan Kesehatan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian

Woro Supadmi

Universitas Ahmad Dahlan

Author-ID : 393168

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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EVALUASI PENGGUNAAN OBAT ANTI HIPERTENSI PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS Supadmi, Woro
Pharmaciana Vol 1, No 1 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The intervention led to various complications in dialysis patients includehypertension intradialitik as a result of hemodynamic changes.The phenomenon of theparadox of which caused activation of endogenous vasopresor due to changes involume status and antihypertensive medication terdialisisnya factor. This study aims todetermine patterns of use of antihypertensive drugs, evaluating the rationality and sideeffects of antihypertensive drugs based on literarur. This study was performed with thepatientâs condition based on the observation of patients to see medical records drugdata, laboratory data of patients and patientâs condition.Retrospective study ofhemodialysis patients in the hospital PKU Muhammadiyah Yogyakarta year periodfrom 2009 to 2010. Patients according to inclusion criteria, anti-hypertensive drugreceipts and complete medical record data. Evaluation of rationality involves the use ofantihypertensive drugs right dose, right patient and side effects based on the DrugInformation Hand Book 2005, Handbook of Clinical Drug Data, 2002. The study found60 patients who fit the inclusion criteria. Based on the research patterns of use ofantihypertensive drugs in patients with hemodialysis is captoril, furosemide, nifedipine,lisinopril, amlodipine, valsatran and clonidin. Evaluation rationality inappropriate useof drugs dose use of captopril 11 patients of 34 patients and furosemide 18 patients from52 patients, inappropriate use of captopril patients was 9 patients of 34 patients.Sideeffects that occur in patients with hypokalemia due to the use of furosemide is 40patients, cough due to captopril was 13 patients, side effects of nifedipinegastrointestinal disorders cough and 11 patients, 5 patients coughlisinopril. Conclusion:he use of antihypertensive medications in hemodialysispatientsat RSU PKU Muhammadiyah Yogyakarta is rational.

PENGARUH PEMBERIAN INFORMASI OBAT TERHADAP TINGKAT KEPATUHAN PENGGUNAAN ANTIBIOTIKA PADA PASIEN ISPA DI PUSKESMAS KOTAGEDE I YOGYAKARTA Muljabar, Stefy Muliyani; Supadmi, Woro
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

ARI is an acute respiratory infection requiring antibiotics. The use of antibiotics shouldbe routinely to prevent resistance. The design of this research was experimental by treatment ofthe cases. How to collect the data used prospective method. The subjects of research who fulfilthe inclusion criteria were 44 patients with acute respiratory infection were divided into twogroups: 22 patients who were given information as the treatment group and 22 patients whowere not given information as the control group. Data was collected through interview to knowthe rest of the drug and questionnaires filling compliance with Modification Morisky AdherenceScale (MMAS). The pattern for antibiotic used in patients of acute respiratory infection atcommunity health centre Kotagede I Yogyakarta were Amoxicillin (65.9%), Cotrimoksazol (25%), Erithromycin (6.8%), and Ciprofloxacin (2.3%). The level of patients compliance byquestionnaire MMAS was 59.09% high compliance, and 40.91 % low compliance. The level ofpatients compliance by the rest of drug was 86.36% and patients uncompliance was 11.36%.The results of questionnaire MMAS with the Chi-Square test p=0.220 (p>0.05), this shows thatgiving drug informations had no influence to level compliance for antibiotic used in patiens ofacute respiratory infection at Community Health Centre Kotagede I Yogyakarta.

Quality of Life and Adherence of Diabetic Patients in Different Treatment Regimens Perwitasari, Dyah A.; Adikusuma, Wirawan; Rikifani, Shoma; Supadmi, Woro; Kaptein, Adrian A.
Indonesian Journal of Clinical Pharmacy Vol 3, No 4 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

The diabetic patientâs quality of life and adherence should be a concerned by health care providers. This study aimed to explore the diabetic patientâs quality of life and medication adherence into account. We recruited 88 subjects in a cross-sectional design. The research subjects were out-patients with type 2 diabetes mellitus in a private hospitals in Yogyakarta City who had taken single or combination of oral anti diabetic and insulin at least six months prior to quality of life measurement. Patients were classified into three groups (monotherapy, oral combination therapy, and oral-insulin combination group). The domains of physical function, energy, satisfaction treatment, and treatment effect were significantly different among the three groups. There were significant associations between treatment satisfaction domain and adherence in monotherapy and oral-insulin combination groups, the health pressure domain and adherence in oral-insulin combination group, the treatment satisfaction domain with adherence in first two groups, and health pressure domain with adherence in oral-insulin combination group. In conclusion, the quality of life of the diabetic patients was good and their medication adherence was at a moderate level.Key words: Adherence, diabetes, Indonesia, quality of lifeÂ Kualitas Hidup dan Kepatuhan Pasien Diabetes Melitus dengan Pengobatan yang BerbedaKualitas hidup dan kepatuhan pasien diabetes melitus (DM) sebaiknya mendapat perhatian dari pemberilayanan kesehatan. Penelitian ini bertujuan untuk mengetahui kualitas hidup pasien DM dan hubungannya dengan kepatuhan pasien. Penelitian ini dilakukan dengan menggunakan rancangan potong lintang. Subjek penelitian ini adalah 88 orang pasien DM tipe 2 di suatu rumah sakit swasta di Yogyakarta yang memperoleh pengobatan baik tunggal maupun kombinasi antara antidiabetes oral dan insulin minimal enam bulan sebelum pengambilan data kualitas hidup. Pasien dikategorikan menjadi tiga kelompok, yaitu kelompok monoterapi, kombinasi oral antidiabetes, dan kombinasi oral-insulin. Terdapat perbedaan yang signifikan antara ketiga kelompok ini pada domain fungsi fisik, energi, kepuasan terhadap terapi, dan efek pengobatan. Terdapat hubungan signifikan antara domain kepuasan pasien dengan kepatuhan pada kelompok monoterapi dan terapi kombinasi oral, domain tekanan kesehatan dengan kepatuhan pada kelompok terapi kombinasi oral-insulin, serta domain kepuasan pasien dan tekanan kesehatan dengan kepatuhan pasien pada ketiga kelompok terapi. Kualitas hidup pasien DM pada penelitian ini cukup bagus dengan kepatuhan pada tingkat moderat.Kata kunci: Diabetes, kepatuhan, kualitas hidup, Indonesia

ANALISIS COST-EFFECTIVENESS PENGGUNAAN SEFTRIAKSON DAN SEFOTAKSIM PADA TERAPI PROFILAKSIS APENDEKTOMI DI RS PKU MUHAMMADIYAH YOGYAKARTA TAHUN 2006-2007 Muhartati, Sri Aisyah; Muhlis, Muh; Supadmi, Woro
Pharmaciana Vol 1, No 2 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Cost-effectiveness analysis of ceftriaxone and cefotaxim prophylactic antibioticsof appendectomy in PKU Muhammadiyah Hospital Yogyakarta from January 2006 toDecember 2007 has been studied. This study was aimed to explore the direct medicalcost, cost-effectiveness ratio, and determine whether drugs of ceftriaxone or cefotaximwhose had more effective cost. This study was carried out by descriptive retrospectivedesign. The population was all inpatients of appendectomy getting prophylaxisantibiotics with either ceftriaxon or cefotaxim therapy in PKU MuhammadiyahHospital Yogyakarta. The population target were the appendectomy patients in thethird class of PKU Muhammadiyah Hospital Yogyakarta from January 2006 toDecember 2007. The result indicated that direct medical cost of the patients gettingceftriaxone therapy was Rp 422.257, whereas the cost of the patients getting cefotaximtherapy was Rp 487.680. Cost-effectiveness ratio of whom getting ceftriaxone therapywas Rp 105.564/day, whereas the ratio of whom getting cefotaxim therapy was Rp162.560. Finally, it have not been able to determine which drug is more cost-effective.

KAJIAN INTERAKSI OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI BANGSAL RAWAT INAP RSU PKU MUHAMMADIYAH YOGYAKARTA PERIODE TAHUN 2010 Rahmiati, Siti; Supadmi, Woro
Pharmaciana Vol 2, No 1 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Drug interactions are one of the Drug Related Problems (DRPs) that may affectpatient treatment outcomes. Hypertension occurs in approximately 10% to 81.5% ofhemodialysis patients. The purpose of this study was to determine the incidence ofantihypertensive drug interactions in hemodialysis patients in the inpatient wards PKUMuhammadiyah Hospital of Yogyakarta period in 2010. This study descriptive design.Data retrieved retrospectively. Data retrieval were done by taking all the data thatmeet the criteria of existing research on the medical records of hemodialysis patients inPKU Muhammadiyah Hospital of Yogyakarta who received antihypertensive withabove normal blood pressure (= 130/80 mmHg). Data were analyzed based on thedescriptive level of significance, onset, and severity. The results showed that there were54.79% (40 patients) of 73 hemodialysis patients potentially experienced druginteractions. Antihypertensive drugs most widely used in hemodialysis patients wereACEI, CCB, and diuretics. Incidence of antihypertensive drug interactions 27 cases(45.76% were most common at a significance level 3, 48 cases (81.36%) were onsetdelayed, and the severity minor of 44 cases (74.58%). The mechanism of interactionspharmacodynamic were 37 cases (62.71%) of the total 59 events that have druginteractions. Drugs often interactions were furosemide and captopril.

Evaluasi terapi erytropoetin pada pasien hemodialisa di rumah sakit PKU Muhammadiyah Yogyakarta Adnan, Adnan; Dania, Haafizah; Supadmi, Woro
Pharmaciana Vol 8, No 2 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Most of the patients with end-stage renal disease who undergoing hemodialysis received erythropoietin (EPO) therapy for the anemia treatment. Deficiency anemia erythropoietin is a common complication of chronic kidney disease (CKD). EPO therapy is expected to improve the anemia and can improve the quality of life of patients.This study was conducted in an analytic observational with Cross Secsional design. The purpose of this study was to know there was a difference of red blood cell profile involve hemoglobin (Hb), Mean Corpusculair Volume (MCV), Mean Corpusculair Haemoglobin (MCH), Mean Corpusculair Haemoglobin Concentration (MCHC) and quality of life of CKD patients who received EPO and non EPO therapy in PKU Muhammadiyah Yogyakarta Hospital. Inclusion criteria in this study were PGK ICD N18.9 patients who were undergoing hemodialysis therapy at RS PKU Muhammadiyah Yogyakarta, outpatient, can read and understand the questionnaire, and accept to be a respondent.The results of this study showed no significant difference (p>0,05) in red blood cell (Hb, MCV, MCH, MCHC) between EPO and non EPO therapy groups. The associated of EPO with the quality of life of patients in all of KDQOL domains was p> 0.05.The conclusions of this study showed that there was no significant difference between EPO and Non EPO therapy and there was no correlation between EPO and non EPO therapy with quality of life of hemodialysis patients.

Proportion and Factors Predicted Self- Medication in Elderly Population in Yogyakarta Sari, Andriana; Supadmi, Woro; Perwitasari, Dyah Aryani
Media Farmasi: Jurnal Ilmu Farmasi Vol 12, No 1: Maret 2015
Publisher : Universitas Ahmad Dahlan

Pharmacists should give more attention in giving pharmaceutical care services to the elderly patients, because the decrease of physiological function could result more drug related problems. Currently, elderly patients are interesting to do self- medication before visiting the physician. Thus, our study was aimed to understand the proportion of elderly patients who are interesting to do the self-medication and to explore the factors predicted self-medication behavior. This study was carried out by cross-sectional design. Data was collected by doing interview and giving questionnaire to the 544 elderly patients in the pharmacies of YogyakartaProvince which were chosen by proportional area sampling method. Data was analyzed descriptively and using the chi square test to understand factors which could be influenced self medication behavior. Most of the patients choose to do the self medication (63.6%) rather than directly went to the physician (36.4%). There were 3 predictors of self medication behavior in our study, which were occupation, income and type of disease with the RR were; 0.823 (95% CI:0.7010.965), 1.433 (95% CI:1.173-1.751) and 1.027 (95% CI: 1.059-1.376), respectively.The occupation, income and chronic disease could predict of self medication behavior in elderly patients.Keywords: self medication, elderly, predictor

EVALUASI KEPATUHAN PASIEN DIABETES MELITUS TIPE 2 DI RUMAH SAKIT UMUM PKU MUHAMMADIYAH BANTUL, YOGYAKARTA Adikusuma, Wirawan; Perwitasari, Dyah Aryani; Supadmi, Woro
Media Farmasi: Jurnal Ilmu Farmasi Vol 11, No 2: September 2014
Publisher : Universitas Ahmad Dahlan

Diabetes melitus merupakan sekumpulan penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau kedua-duanya. Penelitian ini dilakukan untuk mengetahui kepatuhan pasien DM tipe 2 di RSU PKU Muhammadiyah Bantul.Penelitian ini dilakukan dengan metode observasional crossectional dengan mengambil data pasien secara prospektif selama periode Oktober – Desember 2013. Subyek penelitian adalah pasien diabetes melitus tipe 2 rawat jalan di RSU PKU Muhammadiyah Bantul yang telah menerima antidiabetik oral minimal 6 bulan terapi sebelum pengukuran kepatuhan. Subyek yang memenuhi kriteria inklusi sejumlah 56 pasien diabetes melitus tipe 2 dibagi menjadi dua kelompok yaitu kelompok monoterapi sejumlah 24 pasien dan kelompok kombinasi terapi sejumlah 32 pasien. Pengumpulan data dilakukan dengan melakukan wawancara dan pengisian kuesioner Medication Adherence Report Scale (MARS) untuk mengukur kepatuhan. Hasil penelitian menunjukkan bahwa tingkat kepatuhan antara monoterapi dan kombinasi terapi berbeda signifikan (p>0,05). Pada faktor karakteristik hanya jenis kelamin yang berpengaruh terhadap kepatuhan [RR=0,463; interval kepercayaan 95%: 0,202-1,062] Kata kunci: DM tipe 2, kepatuhan, MARS

MONITORING EFEK SAMPING PENGGUNAAN ANTITROMBOTIK PADA PASIEN INFARK MIOKARD AKUT Perwitasari, Dyah Aryani; Supadmi, Woro; Kurniyati, .
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 5, No 1 (2010)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

Acute myocardial infarction (AMI) is one of coronary artery disease that has high rate of mortality and morbidity. The use of antithrombotic has ben recomended widely as the main therapy of AMI. The benefit from using aspirin in high-risk vascular disease patients comes at the cost of increased gastrointestinal complications, such as gastroduodenum ulcerations. This research aimed to know the monitoring of antithrombotics’side effects AMI patients in a private hospital of Yogyakarta from Januari to Desember 2007. The research used descriptive method and the data was collected from patients’ medical records with AMI as primary diagnose. Result of research showed that antithombotics drugs which applied as therapy at AMI patient were antiplatelets, anticoagulants and thrombolytics. We identified the side effects monitoring such as; haemorrhage risk in 3,90% (2 patients), thrombocytopenia in 3,90% (2 patients) and renal function in 15,58% (12 patients). There were no patients with gastrointestinal disorder as antithrombotics’side effects. Intensive blood pressure monitoring was done for patient who get thrombolytic therapy (21 patients) that was equal to 26,92% from total patients. ABSTRAK Infark miokard akut (IMA) merupakan jenis penyakit jantung koroner yang mempunyai tingkat morbiditas dan mortalitas yang tinggi. Antitrombotik merupakan terapi utama dari IMA. Penggunaan aspirin sebagai terapi IMA sering disertai dengan meningkatnya komplikasi gastrointestinal. Komplikasi tersebut bisa berupa tukak gastroduodenal, dispepsia dan esofagistis. Penelitian ini dilakukan untuk mengetahui tindakan monitoring efek samping antitrombotik yang telah dilakukan pada pasian infark miokard akut di sebuah rumah sakit swasta di Yogyakarta periode Januari-Desember 2007. Penelitian dilakukan dengan metode non eksperimental dan data monitoring dilihat pada rekam medis pasien IMA. Hasil dari penelitian ini menunjukkan bahwa terapi antitrombotik yang digunakan pada infark miokard akut adalah antiplatelet, antikoagulan dan trombolitik. Monitoring efek samping antitrombotik yang telah dilakukan berupa monitoring perdarahan pada 2 pasien (3,90%), trombositopenia pada 2 pasien (3,90%), fungsi ginjal pada 12 pasien (15,58%). Tidak ada pasien yang mengalami gangguan gastrointestinal akibat efek samping antitrombotik. Monitoring tekanan darah secara intensif hanya dilakukan pada pasien IMA yang mendapat terapi trombolitik yaitu 21 pasien atau sebesar 26,92% dari total pasien IMA.

MONITORING EFEK SAMPING PENGGUNAAN ANTITROMBOTIK PADA PASIEN INFARK MIOKARD AKUT Perwitasari, Dyah Aryani; Supadmi, Woro; Kurniyati, .
Jurnal Farmasi Indonesia Vol 5, No 1 (2010)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v5i1.32

Acute myocardial infarction (AMI) is one of coronary artery disease that has high rate of mortality and morbidity. The use of antithrombotic has ben recomended widely as the main therapy of AMI. The benefit from using aspirin in high-risk vascular disease patients comes at the cost of increased gastrointestinal complications, such as gastroduodenum ulcerations. This research aimed to know the monitoring of antithromboticsâ??side effects AMI patients in a private hospital of Yogyakarta from Januari to Desember 2007. The research used descriptive method and the data was collected from patientsâ?? medical records Â with AMI as primary diagnose. Result of research showed that antithombotics drugs which applied as therapy at AMI patient were antiplatelets, anticoagulants and thrombolytics. We identified the side effects monitoring such as; haemorrhage risk in 3,90% (2 patients), thrombocytopenia in 3,90% (2 patients) and renal function in 15,58% (12 patients). There were no patients with Â gastrointestinal disorder as antithromboticsâ??side effects. Intensive blood pressure monitoring was done for patient who get thrombolytic therapy (21 patients) that was equal to 26,92% from total patients. ABSTRAK Infark miokard akut (IMA) merupakan jenis penyakit jantung koroner yang mempunyai tingkat morbiditas dan mortalitas yang tinggi. Antitrombotik merupakan terapi utama dari IMA. Penggunaan aspirin sebagai terapi IMA sering disertai dengan meningkatnya komplikasi gastrointestinal. Komplikasi tersebut bisa berupa tukak gastroduodenal, dispepsia dan esofagistis. Penelitian ini dilakukan untuk mengetahui tindakan monitoring efek samping antitrombotik yang telah dilakukan pada Â pasian infark miokard akut di sebuah rumah sakit swasta di Yogyakarta periode Januari-Desember 2007. Penelitian dilakukan dengan metode non eksperimental dan data monitoring dilihat pada rekam medis pasien IMA. Hasil dari penelitian ini menunjukkan bahwa terapi antitrombotik yang digunakan pada infark miokard akut adalah antiplatelet, antikoagulan dan trombolitik. Monitoring efek samping antitrombotik yang telah dilakukan berupa monitoring perdarahan pada 2 pasien (3,90%), trombositopenia pada 2 pasien (3,90%), fungsi ginjal pada 12 pasien (15,58%). Tidak ada pasien yang mengalami gangguan gastrointestinal akibat efek samping antitrombotik. Monitoring tekanan darah secara intensif hanya dilakukan pada pasien IMA yang mendapat terapi trombolitik yaitu 21 pasien atau sebesar 26,92% dari total pasien IMA.

Co-Authors . Fitriyani Adnan, Adnan Adrian A. Kaptein Adrian A. Kaptein Ajeng Diantini Akrom, Akrom Anak Agung Gede Sugianthara Andriana Sari Andriana Sari Antoni, Priski Aristia, Bella Fevi Armina Hikmawati Atikah Nur Shabrina Aulia Kurniapuri Auliya A. Suwantika Bambang Purwoko Budiyono Budiyono Cut Fatia Ulfa Cut Fatia Ulfa Damayanti, Elok Della Midi Wardhani Dyah A. Perwitasari Dyah A. Perwitasari Dyah Aryani Perwitasari Dyah Aryani Perwitasari Dyah Aryani Perwitasari Ela Fadilah Pramsa Endah Karuniawati Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Endang Yuniarti Fitri Ayu Wahyuni Fitri Ayu Wahyuni Fitri Qoriawaty Fitriyani Fitriyani Fitriyani, Fitriyani Ginanjar Zukhruf Saputri Gita Husna Rahmadani Haafizah Dania Hanindia Riyani Hanita Christiandari Herjanti Ratnawiningsih Hesty Riza Oktastika Hidayah Apriliawan Hidayati, Ana Iin Ike Ardiani Ilham Bintang Agung Imaniar Noor Faridah Joko Sudibyo Joko Sudibyo Jumiati Kaptein, Adrian A. Kurniyati, . Kurniyati, . Lukman Hakim Muh Muhlis Muhammad Muhlis Muhammad MuMuhlis Muhartati, Sri Aisyah Muhlis, Muh Murwiningsih Murwiningsih Musa Fitri Fatkhiya Nur Shabrina, Atikah Perwitasari, Dyah A. Priski Antoni Qarriy 'Aina Urfiyya Rahmiati, Siti Ratna R. Restu Pranandari Rikifani, Shoma Ruri Renggani Sandra Shabran Hadiq Shoma Rikifani Siti Rahmiati Siti Rahmiati Sri Aisyah Muhartati Sri Aisyah Muhartati Sri Awalia Febriana Stefy Muliyani Muljabar Sulastri Sulastri Susilo, Rinto Tina Rostinawati Triyo Nova Wirawan Adikusuma Yulia Indah Widianti Yuptarol Mujahidah

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