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All Journal HAYATI Journal of Biosciences Jurnal Fitopatologi Indonesia Jurnal Teknologi Dan Industri Pangan Jurnal Akuakultur Indonesia Jurnal Pengolahan Hasil Perikanan Indonesia Jurnal Ilmu dan Teknologi Kelautan Tropis Berkala Perikanan Terubuk BIOTROPIA - The Southeast Asian Journal of Tropical Biology Current Biochemistry Journal Jurnal Kelautan Tropis Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Marinade Jurnal Teknologi Pertanian Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan JURNAL PERIKANAN TROPIS Asian Journal of Aquatic Sciences COJ (Coastal and Ocean Journal) Barakuda 45
Kustiariyah Tarman
Departemen Teknologi Hasil Perairan, Fakultas Perikanan Dan Ilmu Kelautan, IPB University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Medicine & Pharmacology Social Sciences Veterinary

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Journal : Berkala Perikanan Terubuk

 1 
AKTIVITAS ANTIOKSIDAN PADA FORMULA TABLET TERIPANG KELING (Holothuria atra) Ahmad Fauzan Lubis; Sri Purwaningsih; Kustiariyah Tarman
Berkala Perikanan Terubuk Vol 44, No 2 (2016): Juli 2016
Publisher : Fakultas Perikanan dan Kelautan, Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.002 KB) | DOI: 10.31258/terubuk.44.2.51 - 69

Abstract

This study about activity of antioxidant aimed to determine the chemical characterization of sandfish, sandfish meat and sandfish powder, determine the best formulation in manufacturing Holothuria atra tablet based on DEPKES RI standard and to determine the antioxidant activity and the active compounds that act as antioxidants in the extract of Holothuria atra tablets. The method used in the manufacture of tablets is the direct compression method using 6 formulations to treat the kind of powder substance that is the ingredient of sandfish are intact and substances from the meat of sandfish. Tablet chosen based on the standards of the Ministry of Health that includes the physical characteristics of the test tablet and shelf-life stability. Tablet rivet sandfishtested the antioxidant activity by the method of 2,2-diphenyl-1-picrylhydrazyl (DPPH). Tests to determine the active compounds that act as antioxidants with thin layer chromatography (TLC) and bioautography antioxidants and also to determine the functional groups using analysis of Fourier Transform Infrared (FTIR). The yield of sandfish powder is considerably low. Yield of sandfish powder are 10.26% and sandfish meat powder are 9,82%. The protein content of sandfish powder are 60,89% lower compared to sandfish meat powders of 63,57%. Formula elected from the sandfish tablet test based on physical characteristics and stability test of the shelf life of the tablet is the formula A2 with the composition of the powder formulation Holothuria atra (25%), Ac-Di-Sol (2%), L-HPC (2%), Aspartame (0.5%), menthol (0.2%), talk (1%), magnesium stearate (1%) and lactose: mannitol (67.8%) and has antioxidant activity with IC50 value of 97.22 ppm. TLC test and Bio-autography showed that the class of antioxidant compounds are steroid, and suspected compounds at FTIR test, that act as antioxidants compound has similarities to the sterol class.
Co-Authors - - nurjanah A. Alhana A. Zaenal Mustopa Abdul Basir Agus Sabdono Agus Trianto Ahmad Fauzan Lubis anak agung putu ayu puspita negara Anisa Gianti Zhafira Apon Zaenal Mustopa Aulia Andhikawati Azwin Apriandi Azwin Apriandi Azwin Apriandi Bugi Ratno Budiarto Bustami Ibrahim Desniar . Dinamella Wahjuningrum dita aguistina barus Dwi Safitri Efi Toding Tondok Ekowati Chasanah Endar Marraskuranto Hana Nurullita Prestisia Hartoyo Notonegoro Hartoyo Notonegoro Hawis H Madduppa Heder Djamaludin HEDI INDRA JANUAR Hedi Indra Januar Hendra Susanto Hendra Susanto Imra Imra Iriani Setyaningsih Irzal Effendi Jae-Kwan Hwang Mada Triandala Sibero Mada Triandala Sibero MEGA SAFITHRI Mega Safithri Mega Safithri Meydia Meydia Meydia Meydia Meydia Mita Gebriella Inthe Muhammad Nursid Muhammad Nursid Munandar, Aris Munti Yuhana Nabila Ukhty Neni Widowati Novriyandi Hanif Nur Asmasari Syam Nur Syafiqoh Nurjanah - - Nurjanah Nurjanah Nurul Mutia Putram Nurzakiah Nurzakiah Nurzakiah Nurzakiah Ocky Karna Radjasa Pipih Suptijah Prayoga Pannindriya Prayoga Pannindrya Purwantiningsih Sugita putri, R Marwita Sari Putri, Raja Marwita Sari Putriana Sari Sirait Putu Kristiani Kalontong R. Marwita Sari Putri R. Marwita Sari Putri Rita Sahara Riviani Riviani Sari Putri, R. Marwita Sihono Sihono Sri Hariati Sri Purwaningsih Susanto, Hendra Swestri Utami TATI NURHAYATI Taufik Indarmawan Teuku Reza Efianda Tiara Ulfa Bachtiarini Uju Vepryany Oktaviarty Vitriyanna Mutiara Yuhendri Wahyu Ramadhan Widodo Widodo Woro Hastuti Setyantini Yogiara Yogiara Yulia Oktavia Yusro Nuri Fawzya Zafira Khoirunnisa