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All Journal Pharmascience Berkala Kedokteran BIOEDUSCIENCE Jurnal Ilmiah Manuntung JSFK (Jurnal Sains Farmasi & Klinis) JCPS (Journal of Current Pharmaceutical Sciences) Bubungan Tinggi: Jurnal Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Pharmaceutical Care and Sciences Jurnal Bakti Untuk Negeri Sains Medisina Health Research Journal of Indonesia Jurnal Farmasi SYIFA Benzena Pharmaceutical Scientific Journal Parapemikir Jurnal Ilmiah Farmasi Jurnal Pengabdian Masyarakat Panacea
Saftia Aryzki
Universitas Sari Mulia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Uji Aktivitas Antidiare Ekstrak Etanol Daun Ramania (Bouea macrophylla) Terhadap Mencit Betina Galur Swiss Webster Saftia Aryzki; Ayu Safitri; Yesika Yesika
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p35-44

Abstract

Diarrhea is still one of the leading causes of morbidity and mortality in almost all geographical regions of the world. All age groups are susceptible to diarrhea, but severe disease with high mortality is especially common among infants and children. In developing countries, children suffer from diarrhea more than 12 times per year and it accounts for 15 - 34 percent of all deaths. The ramania plant is green when young, and is often consumed as a salad or a mixture of ramania chili sauce. Ramania leaf extract contains several secondary metabolites, one of which is tannin, which has activity as antidiarrheal with the mechanism that the broken down tannate protein will bind to hydrolyzed tannin and pass through the intestine so that it can reduce the secretion of the small intestine and cause constipation. This research method is true experimental with pre-post test design with randomized control group design method with female Swiss Webster mice. The results suggest that the extract has met the parameters of simplisia standardization and extract standardization. The extract is proven to contain flavonoids, tannins, alkaloids, saponins, anthraquinones, phenolics, and terpenoids. Ramania leaf extract is proven to have antidiarrheal activity with a concentration of 400mg / kgBB against oleum ricini-induced mice based on the parameters of diarrhea onset time, decreased diarrhea frequency, and duration of diarrhea. Ethanol extract of ramania leaves at a dose of 400 mg/kgBB provides the best antidiarrheal activity against mice induced by oleum ricini.
PENGARUH FABRIKASI BERUPA PERBANDINGAN PRODUK OBAT PATEN PANADOL DAN SANMOL Shinta Rahmawati; Saftia Aryzki
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p56-59

Abstract

Availability is a measure of the rate and amount of a therapeutically active drug that reaches the general circulation. As for bioequivalence requirements, a requirement made by the Food and Drug Administration (FDA) for in vitro and/or in vivo testing of certain medicinal products, these requirements must be met as a condition for marketing. Bioequivalence of a medicinal product is pharmaceutical equivalent or an alternative is a preparation whose rate and amount of absorption do not differ significantly when given at the same dose and experimental conditions. Several drugs that have the same amount of absorption but differ in absorption rate can be considered pharmaceutical equivalent if the difference in absorption rate does not cause a significant difference in clinical effects.
Co-Authors Agenia Rahman Aisyah, Noor Akrom, Akrom Ana Khumaira Sari Anna Khumaira Sari Ansori Rahman Ayu Safitri Ayuchecaria, Noverda Desy Agustina Desy Hereyanti Diah A Puspandari Dwi Rizki Febrianti Dyah Sri Wulandari Dyan Fitri Nugraha Eka Kumalasari Eka Rahmadhania Erlina Syamsu Erna Prihandiwati Fahma Lailani Febrianti, Dwi Rizki Gamaliana, Dian Yunita Gandys Hartaningroom Gina Aima Putri Hidayatun Nisa, Hidayatun Indah Fitri Ramadhani Isnani Yuliana Ita Feteriah Iwan Yuwindry Karani Karani Leonov Rianto Maudy Namirah Raudatullis Wanda Melviani Melviani Melviani Melviani Mochammad Maulidie Alfiannor Saputera Muhamma Rizki Ikhsan Muhammad Nurridho Alfian Humaira Mustaqimah Mustaqimah Noverda Ayuchecaria Novi Damayanti Nungky Yulia Nurul Shadika Khairunnisa Putra, Aditya Maulana Perdana Putri Vidiasari Darsono Rakhmadhan Niah Ratu Mouly Noor Rina Saputri Riza Alfian Riza Alfian Riza Alfian Ronal Manurung Saftia Aryzki Saftia Aryzki Saftia Aryzki Saftia Aryzki Setia D. R. Riadi Shela Puzi Dina Shinta Rahmawati Siska Musiam Siti Mutaharah Subhannur Rahman Susanto, Yugo Tri M Andayani Wahyu Nugroho Wahyu Nugroho Wahyuni, Amaliyah Yesika Yesika Yusuf Anggoro Mukti