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All Journal Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) Majalah Info Sains Journal of Pharmaceutical and Sciences.
Douglas N. Pareta
Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Journal : Journal of Pharmaceutical and Sciences.

 1 
Uji Efektitivitas Sediaan Gel Ekstrak Daun Kemangi (Ocimum basilicum L) Terhadap Penyembuhan Luka Sayatan Tikus Putih (Rattus nornvegicus) Anastasia Walukow; Douglas N. Pareta; Silvana L. Tumbel; Joke L. Tombuku; Christel N. Sambou
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.173

Abstract

Natural wealth has a variety of herbal plants, plants that are included in it efficacious as medicine. Traditional medicine, is an ingredient or herb that is usually used as traditional medicine and is used to accelerate the healing of diseases, one of the plants used to accelerate wound healing is basil leaves (Ocimum basilicum L.). This study aimed to determine the effectiveness of basil leaf gel preparations against wound healing in white rats (Rattus norvegicus). The test animals used were 15 rats. A 1 cm cut wound is made on the back of the mouse using a scalpel. The method used in this study is in the form of laboratory experiments. This study used a Complete Randomized Design (CDR) consisting of 5 treatments, including 1 negative control, 1 positive control (bioplacenton), and 3 stratified concentrations, namely 5% concentration gel, 10% concentration gel and 15% concentration gel with 3 repetitions each. The treatment is carried out for 7 days. The results of measuring wound diameter in rats based on the results showed that basil leaf extract gel concentration of 15% provided a healing effect more effective than other extracts.
Uji efektitivitas sediaan gel ekstrak bonggol pisang goroho putih (Musa acuminafe, sp) terhadap penyembuhan luka bakar tikus putih (Rattus nornvegicus) Martina G. Laloan; Douglas N. Pareta; Selvana S. Tulandi; Yessie K. Lengkey; Christel N. Sambou
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.184

Abstract

Natural wealth has a variety of herbal plants, plants that are included in it efficacious as medicine. Traditional medicine, is an ingredient or herb that is usually used as traditional medicine and is used to accelerate the healing of diseases, one of the plants used to accelerate wound healing is the white goroho banana weevil (Musa acuminafe, sp). This study aimed to determine the effectiveness of banana weevil gel preparations against healing burns in white rats (Rattus norvegicus). The test animals used were 15 rats. A burn of 2.5 cm was made on the back of the mouse using metal coins. The method used in this study is in the form of laboratory experiments. This study used a Complete Randomized Design (RAL) consisting of 5 treatments, including 1 negative control, 1 positive control (bioplacenton), and 3 stratified concentrations, namely 5% concentration gel, 10% concentration gel and 15% concentration gel with 3 repetitions each. The treatment is carried out for 14 days. The results of measuring wound diameter in rats based on the results showed that banana weevil extract gel concentration of 15% provided a healing effect more effective than other extracts.
Uji Aktivitas Ekstrak Etanol Daun Labu Siam (Sechium edule Jacq. Swartz) sebagai Antibakteri Mycobakterium smegmatis Christel Sambou; Douglas N. Pareta; Sarah Sambow; Wilmar Maarisit; Jabes Kanter; Jeane Mongi; Hanna M. Rumagit; Selvana Tulandi; Joke L. Tombuku; Reky R. Palandi; Nerni O. Potalangi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.217

Abstract

The membrane structure of Mycobacterium smegmatis is similar to that of Mycobacterium tuberculosis, allowing TB testing to be performed on Mycobacterium smegmatis without directly testing on Mycobacterium tuberculosis. Antibacterial testing uses the paper disc method with several treatments, namely extract concentrations of 1 µg/disc, 2 µg/disc, and 4 µg/disc, as well as positive control streptomycin 2 µg/disc and negative control 70% ethanol. The research results obtained at Extract Concentrations of 1, 2, and 4 µg/disc have moderate antibacterial activity seen from the inhibitory zone diameter, namely 8.73 mm, 9.17 mm, and 9.73 mm, and the positive control is strong because it has a zone diameter of 13.27 and the negative control does not give a zone. The conclusion is that the extract of siam pumpkin leaves has moderate antibacterial activity.
Co-Authors Aditia Biasa Amal Ginting Anastasia Walukow Anatasya Mongdong Andhika Ratu Asmiati Mulkin Carolina Nifinluri Christi Devita Laoh Christian J. A. Tapehe Deby Mongi Dian K. Ta’au Felicia T. Rawung Ferdy A Karauwan Florendo F. Tuegeh Franky Sangande Friska M. Montolalu Gideon A. R. Tiwow Hanna M. Rumagit Hanna M. Rumagit Hanny Tompodung Hariawani Bauda Hariyadi Hariyadi Haryadi Haryadi Hellen Matindas Indriani Maitulung Jabes W. Kanter Jacky Karel Simboh Jeane Mongi Jeane Mongi Jeniver Lengkong John Paul Rian Johrawati Aritan Joke L. Tombuku Joke L. Tombuku Joke L. Tombuku Joke Tombuku Karauwan, Ferdy Martina G. Laloan Meyske Manapode Mirabella V. Moningka Monica Sarra Tamunu Nerni O. Potalangi Nerni O. Potalangi Olvie S Datu Olvie S. Datu Palandi, Reky Paula Rumagit Rahmat S. Santoso Randi Tampa’i Randy Tampa'i Randy Tampa’i Recky A.L. Simatupang Reky R. Palandi Reynald Repi Rudy Pareda Sambou, Christel N. Sarah Sambow Selvana S. Tulandi Selvana S. Tulandi Selvana Tulandi Selvana Tulandi Severalen E. Saruan Silvana L. Tumbel Silvana L. Tumbel Silvana L. Tumbel Stevanie elisabeth Davis Tabita R. S. Rongkonusa Tresya Anuku Untu, Sonny Venly Y.D. Warouw Vivit A. Baura Vlagia I. Paat Wilmar Maarisit Yessie K. Lengkey Yessie K. Lengkey