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Jurnal Ilmu Kedokteran (Journal of Medical Science)

jik
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Published by Universitas Riau

ISSN : 1978662X EISSN : 27154467 DOI : https://doi.org/10.26891/JIK

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

Journal of Medical Science receives a script from health and medical lecturer, undergraduate, residents, hospital staff and those who interested in writing scientific papers. The scientific articles posted on JIK include: literature reviews, research article, case report and EBCR (Evidence Based Case Report). Article preferably basic science of medicine and health.

Arjuna Subject : Kedokteran - Review dan Referensi, Kedokteran

Articles 208 Documents

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Kualitas Visum et Repertum Perlukaan di RSUD Indrasari Kabupaten Indragiri Hulu Periode 1 Januari 2009-31 Desember 2013 Dedi Afandi; Tuti Restuastuti; Winda Kristanti
Jurnal Ilmu Kedokteran Vol 9, No 1 (2015): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Visum et Repertum (VeR) of injury is the most case that requested by the investigator to emergency physician.Because VeR gives the important role in the judicial process in criminal offense cases, so that the good quality VeR isrequired. This study was aimed to know the quality VeR of injury in Indrasari General Hospital Indragiri Huluregency during 1 January 2009-31 December 2013. This study used descriptive retrospective aproach. This studyused Herkutanto’s score to evaluate 13 subtances in VeR. The sample of this study was all data of VeR of injury inIndrasari General Hospital Indragiri Hulu regency during 1January 2009 -31 December 2013 and the total data inIndrasari Hospital was 137 data. This study suggested that the highest living injury victim are living in the age group22 - 40 years amount 73 VeR (53.28%). The most injury case to the male as much as 92 VeR (67.153%). The highesttype of violence is blunt violent as much as 109 VeR and the most in 22-40 ages group. The VeR quality preliminarypart is 69.34% (medium), the reporting part is 37.83% (poor) and the conclusion part is 49.45% (poor). Based fromthat data, the conclusion of the quality of VeR indrasari hospital is poor (46.82%).

Pencegahan Lesi Aterosklerosis Oleh Asam Alfa Lipoat Pada Aorta Mencit Jantan (Mus Musculus) Yang Diberi Diet Tinggi Kolesterol Ismawati Ismawati; Winarto Winarto; Rezki Permata Sari
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Atherosclerosis can happen easily on animal that are given high cholesterol diet. Alpha lipoic acid is universal antioxidantthat very effective to reduce free radicals, include lipid peroxide. The goal of this research was to find out the prohibitionof atherosclerosis lesion development on male mice aorta that was given high cholesterol diet by alpha lipoic acid. Thiswas an experimental laboratory research with post test only design. Eighteen adult male mice were segregated intothree groups labelled as group NaCl 0,9%, yolks and ALA.. The experiment was design for 6 weeks. The measuredparameter was atherosclerosis lesion score of groups labelled. The statistical test result showed the significant differenceof some tested groups. There was a statistically significant difference between alpha lipoic acid and yolks group (p=0,008),but there is no significant difference was found between ALA and NaCl 0,9% group (p=0,126). As the conclusion, thisstudy proves that alpha lipoic acid has the effects to prohibition of atherosclerosis lesion development on male miceaorta that are given high cholesterol diet.

Ethanol Extracts of Centella asiatica (L.) Urb. Leaf Increase Superoxide Dismutase-2 (SOD-2) Expression on Rat Cerebellar Purkinje Cells After Chronic Stress Desby Juananda; Dwi Cahyani Ratna Sari; Mawaddah Ar-Rochmah; Nur Arfian; Muhammad Mansyur Romi
Jurnal Ilmu Kedokteran Vol 11, No 2 (2017): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Beberapa penelitian menunjukkan bahwa stres kronis meningkatkan produksi reactive oxygen species (ROS), dan /atau menekan mekanisme pertahanan antioksidan. Efek neuroprotektif dari Centella asiatica (L.). Urb telah dilaporkandapat melindungi neuron dari kerusakan oksidatif. Tujuan dari penelitian ini adalah untuk mengetahui efek ekstraketanol C. asiatica leaf terhadap ekspresi superoxide dismutase-2 sel (SOD- 2) pada sel Purkinje serebelum tikussetelah diberikan kejutan kronis di kaki. Sebanyak 25 tikus Sprague Dawley jantan dewasa muda diacak ke dalam limakelompok. Kelompok kontrol negatif terdiri dari tikus yang tidak stres; kelompok kontrol stres menerima aquadest; dankelompok lain diobati dengan dosis yang berbeda (mg / kg berat badan / hari, p.o.) ekstrak etanol daun C. asiatica: 150,300 dan 600, masing-masing diikuti oleh pemberian kejutan kronis di kaki selama dua puluh delapan hari. Ekspresi SOD-2 dari lapisan sel Purkinje diukur menggunakan metode imunohistokimia. Data dianalisis dengan one-way ANOVA (p<0,05). Kami menemukan bahwa ekspresi SOD-2 (%) dari lapisan sel Purkinje untuk kelompok kontrol negatif, kelompokkontrol stres, CeA150, CeA300 dan CeA600 kelompok adalah 22,38 ± 9,73, 9,81 ± 2,21, 10,29 ± 3,60, 14,72 ± 6,65, dan22,75 ± 10,93, masing-masing (p <0,05). Analisis post-hoc menunjukkan perbedaan yang signifikan antara kelompokkontrol negatif dan kelompok kontrol stres (p <0,05). Ada juga perbedaan yang signifikan antara kelompok kontrolstres dan kelompok CeA600 (p <0,05), tetapi tidak ada perbedaan yang signifikan antara kelompok perlakuan (p> 0,05).Penelitian ini menunjukkan bahwa ekstrak etanol daun C. asiatica meningkatkan ekspresi SOD-2 pada sel Purkinjecerebellar tikus setelah stres kronis.

Gambaran Farmakoterapi Pasien Common Cold Di Puskesmas Pekanbaru Dimas Pramita Nugraha; Inayah Inayah
Jurnal Ilmu Kedokteran Vol 10, No 1 (2016): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Common cold is still a disease with the most number of cases in Indonesia and the province of Riau in out patientswho visited the primary health center (Puskesmas). However, in primary health care, like Puskesmas and privatepractice physicians are expected pharmacotherapy common cold is not rational. Medication errors is a common problem.The purpose of this study was to determine how the use of pharmacotherapy in patients with the common cold inPuskesmas Pekanbaru. This study was an observational descriptive , with a total sample 4602 people who meet thespecified criteria .The results showed that the percentage patients common cold using symptomatic analgesic-antipyreticdrugs 70.2%.However, the percentage of patients that using antibiotics in common cold is still quite a lot (36%), alsothe use corticosteroid (17,9%) that showed medication error. The patterns pharmacotherapy of common cold inPuskesmas Pekanbaru was relatively good, but need improvement .

Epilepsi dan Kehamilan Riki Sukiandra
Jurnal Ilmu Kedokteran Vol 8, No 2 (2014): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Epilepsy is a chronic neurologic disorder that may complicate pregnancy, about 25%-33,3% epileptic seizures increasedin pregnancies. The main concern in pregnancies complicated by epilepsy includes the increased risk of congenitalabnormalities associated with antiepileptic drugs. Hormones can have major effect on seizure disorders. Women withepilepsy will have changes in seizure patterns when hormones levels shift, such as during pregnancy or right afterpregnancy. A woman with seizure disorder must be managed effectively to minimize the risk of a seizure that couldharm the fetus. Seizures can harm the developing fetus by reducing the blood supply to the placenta. Anti-convulsantmedications should not be discontinued during pregnancy. medications may be switched to those that are known to bethe safest to the developing fetus. This will reduce the risk for neural tube defects like spina bifida. Multiple drugtherapy should be avoided – if possible– and drugs should be given in divided doses to avoid high peak levels. We canprovide women with epilepsy with the available information, advise on the best treatment prior to pregnancy, andwarnings that most AEDs carry a risk above that of untreated epilepsy. Treatment should be planned in womenanticipating pregnancy

Profil Pasien Hemodialisis Inisiasi Di RSUD Arifin Achmad Provinsi Riau Periode Januari – Desember 2017 Elsa Tubella; Ligat Pribadi Sembiring; Fridayenti Fridayenti
Jurnal Ilmu Kedokteran Vol 12, No 2 (2018): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Hemodialysis is defined as the process of separation, filtering, or cleansing of blood through a semipermeable membrane in patients renal failure. Indication of hemodialysis for both diseases is clinical conditions in addition to laboratory results, such as signs of fluid overload, electrolyte imbalance, metabolic acidosis, and signs of anemia. This study purposed to describe the profile of patients initiation hemodialysis in RSUD Arifin Achmad Riau Province Period January-December 2017. This research was a retrospective descriptive. This study used 94 samples. The number of male patients were higher than female patients (60.6%). The most age group was 40-59 years (57.4%). Second degree of hypertension was 46,8%. The study showed 92.55% of patients had anemia, 50% had hyperkalemia, 56.4% had hyponatremia, and 41.5% had acidosis. Patients consisted of 81.9% chronic kidney disease, and 18.1% acute renal failure.

Aktivitas Antijamur Air Perasan Daun Seledri (Apium graveolens L.) Terhadap Candida albicans Secara In Vitro Patra Inova Ardelia; Fauzia Andrini; M Yulis Hamidy
Jurnal Ilmu Kedokteran Vol 4, No 2 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Celery (Apium graveolens L.) has been known as traditional medicine. Apigenin is one of active component in Celeryleaf that has fungicidal activity, so celery leaf’s extortion suspected has fungicidal activity to Candida albicans. Apigenincan solved in water. The aim of this research was to know antifungal activity of celery leaf’s extortion againsts Candidaalbicans in vitro.This is a laboratory experimental research by using completely randomized design and disc diffusion method. Celeryleaf’s extortion was divided into 3 concentrations, there were 25%, 50% and 100%. Ketoconazole 2% was used aspositive control and aquadest as negative control. The result of this research was based on analysis of variance, therewas significant difference between minimal 2 treatment (p=0.000) and confirmed with Post Hoc test, there were significantdifference in all treatments. As the conclusion, celery leaf’s extortion had antifungal activity againsts Candida albicansin vitro with the best concentration 50% but smaller than ketoconazole 2%.

Hubungan Amplitudo Gelombang Fibrilasi dengan Irama kembali ke Sinus pada Pasien Non Valvular Recent Onset Atrial Fibrillation Chandra Wijaya; Irwan Irwan
Jurnal Ilmu Kedokteran Vol 11, No 1 (2017): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Atrial fibrillation (AF) is a strong risk factor for death with an increase from 1.5 to 1.9 times in the analysis ofFramingham. A Fis also associated with an increase of 5 times the incidence of stroke. Many studies have attemptedto search for any parameters that can predict whether the AFin patients with recent-onset FA can still return to sinusrhythm mornot, but the results still un satisfactory. This is a descriptive analytic study. The subjects were all patientswith recent onset atrial fibrillation (<72 hours). Analysis test conducted by test unpaired T-test for numerical variablesand chi-square test for categorical variables. From 68 subjects there were 36 patients (52.9%) with return to sinus.After analysis showed that Coarse AF (95% CI 0.11 to 0.82, P=0.017) have significant relationship return to sinus inpatients with recent onset atrial fibrillation.

Imunologi Human Immunodeficiency Virus (HIV) dalam Kehamilan Maya Savira
Jurnal Ilmu Kedokteran Vol 8, No 1 (2014): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Human Immunodeficiency Virus can be spread through sexual contact , blood products and vertical transmission ofthe mother to the fetus . The high incidence of HIV / AIDS around the world in women over 15 years old and childrenunder the age of 15 years gives an overview of HIV / AIDS cases in pregnant women likely to have a high incidence.HIV viral RNA viruses belonged to two different types , namely HIV - 1 and HIV - 2 . Most cases are caused by HIV- 1. HIV primarily infects CD4 lymphocytes or T helper ( Th ), the numbers will decrease , as well as the function ofthe immune system will decrease. During pregnancy occurs emphasis on immune cells, with or without HIV infection.Study in France showed no significant progression between the immune system of pregnant women with HIV andnormal pregnant women . T reg on HIV infection in lymphoid tissue accumulated and the number of T reg postpartum was higher in patients with HIV infection compared to HIV- negative . Human Leukocyte antigen - G ( HLA- G ) inhibits cell-mediated immune response and can penetrate the placenta spread of HIV - 1 infection and increasethe risk of vertical transmission . Major histocompatibility complex ( MHC ) encodes HLA - G to inhibit natural killercells ( NK cells) that supports the entry of the virus passes through the placental barrier in HIV- 1 positive pregnantwomen . HIV infection activates CD8 expressing HLA - DR antigen . CD8 immune activation in chronic HIV becomesa factor decreasing CD4 count . The expression of HLA - DR and CD38 on CD8 T lymphocytes that recognize CD4eliminated by HIV infection Total CD8 , CD38 , and HLA - DR is reduced in HIV- positive pregnant women may bea prognostic parameters of immune status.

Profil Pasien Stroke di RSUD Arifin Achmad Provinsi Riau Dimas Pramita Nugraha; Eka Bebasari; Yulia Wardani
Jurnal Ilmu Kedokteran Vol 12, No 1 (2018): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Stroke is the first cause of death in women and the second leading cause of death in men in industrialized countries. In Asia, every year an estimated 500 thousand people experience a stroke. Therefore recognizing stroke risk factors and managing them appropriately is key to designing primary prevention strategies in non-stroke populations and secondary prevention to avoid recurrent strokes. This research was cross sectional study to describe profile stroke patients in Arifin Achmad hospital Riau Province. Research data was taken through questionnaire and patient medical records. In this study, stroke patients in Arifin Achmad Hospital were mostly <60 years old, 65.80% and male sex 64.50%. The proportion of hypertension is 90.80%. Diabetes mellitus 7.90%, dyslipidemia 63.20%, smoking 21.10%, obesity 32.90%, and sedentary life 73.70%.

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Ilhami Romus

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+6281371333123

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jikfkunri@gmail.com

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Riau

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Home Page

OAI Link

Editorial Team

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Reviewer

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Contact Name Ilhami Romus

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Phone +6281371333123

Journal Mail Official jikfkunri@gmail.com

Editorial Address Sekretariat JIK (Jurnal Ilmu Kedokteran) Jl. diponegoro no. 1, Pekanbaru Riau

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Contact Name
Ilhami Romus

Contact Email
ilhamiromus@yahoo.co.id

Phone
+6281371333123

Journal Mail Official
jikfkunri@gmail.com

Editorial Address
Sekretariat JIK (Jurnal Ilmu Kedokteran) Jl. diponegoro no. 1, Pekanbaru Riau

Location
Kota pekanbaru,

Riau

INDONESIA