I Ketut Suwiyoga
Departemen Obstetri Dan Ginekologi, Fakultas Kedokteran, Universitas Udayana, RSUP Sanglah, Bali, Indonesia

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Journal : BALI MEDICAL JOURNAL (BMJ)

DIFFERENCES OF TUMOR MASSES AND HEMOGLOBIN LEVELS IN CERVICAL CANCER SQUAMOUS CELL TYPE PATIENTS TREATED WITH COMBINATION OF PACLITAXEL AND CARBOPLATIN CHEMOTHERAPY Noviyani, R.; Suwiyoga, K.; Lesmana, I.; Niruri, R.; Tunas, K.; Budiana, and I N. K.
BALI MEDICAL JOURNAL Vol 3 No 1 (2014)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Paclitaxel and carboplatin are standard operating procedure for chemotherapy treatment of cervical cancer squamous cell carcinoma at Sanglah General Hospital, Bali-Indonesia. Chemotherapy improves outcome of cancer treatment. However, chemotherapy brings also a variety of adverse effects and complications. This study aims to evaluate the therapeutic and adverse effects of chemotherapy in patients with squamous cell cervical cancer. Methods: This is a case study of six patients with cervical cancer underwent chemotherapy paclitaxel and carboplatin 3-series at Sanglah General Hospital, Bali-Indonesia during January to November 2013. The therapeutic effect of chemotherapy was assessed from cervical cancer tumor mass measured before and after chemotherapy 3-series. The adverse effect of chemotherapy was determined from hemoglobin levels measured before and after chemotherapy. Data were analyzed using a paired t-test with a level of confidence of 95% using the SPSS to find out the differences. Results: In this study we found that there is a difference between tumor mass pre and post 3 series chemotherapy within p < 0.05. In term of toxic effect, we also obtained that there were difference of hemoglobin between pre and post of treatment within p < 0.05. Conclusion: Paclitaxel carboplatin as a chemotherapy drug in patients with cervical cancer is highly recomended when seen from the effects of reduced tumor size, and has a low side effect of anemia (anemia grade 1).
Co-Authors Anak A. A. W. P. Dewi Anak Agung Ngurah Jaya Kusuma Anak Agung Ngurah Jaya Kusuma Anak Agung Ngurah Jaya Kusuma and I G. Alit-Artha Anom Suardika Arthawan Arthawan Budiana, Nyoman Danny Aguswahyudi Dewi, Anak A. A. W. P. E. Joewarini Evert Solomon Pangkahila Feliciano Pinto, Feliciano Ferry Santoso Fido Anggli, Fido Fransiskus C Raharja Hadisubroto, Yona S. Hanny Aditanzil Hanny Aditanzil Heni Sunyoto I Dewa Made Sukrama I Gde Adnyana Sudibya I Gde Raka Widiana I Gde Sastra Winata I Gede Adnyana Sudibya, I Gede Adnyana I Gede M Putra I Gede Mahendra Adiguna Dira I Gede Mega Putra I Gede Putu Surya I Gusti Ayu Sri Mahendra Dewi I Gusti Putu Mayun Mayura I Ketut Labir I Ketut Labir I Ketut Surya Negara I Ketut Tunas I Made Darmayasa I Nyoman Gede Budiana I Nyoman H Sanjaya I NYOMAN MANTIK ASTAWA I Putu Kusuma Yudasmara, I Putu Kusuma I Wayan Artana Putra I Wayan Megadhana I Wayan Putu Sutirta Yasa I Wayan Suranadi I. F. W. Putra I. Lesmana I.W. Weta Ida Bagus Gde Fajar Manuaba Ida Bagus Putra Adnyana Ines Kurniaty Hartono Intan Puspa IPG Wardhiana IPG Wardhiana, IPG Janet Sumampouw JOHANA SENSY LENI MANNA K Tangking Widarsa KADE YUDI SASPRIYANA Kadek Fajar Marta Ketut S. Negara L.S. Ani Leony Lim Lidia Widianti, Lidia Luh Putu Iin Indrayani Maker Luh Seri Ani Made Bagus Dwi Aryana MANNA, JOHANA SENSY LENI Mantik AN Moestikaningsih . Mona Mariana Mona Mariana Muhammad Freddy Candra Sitepu N.W.A. Utami Negara, Ketut S. Ni Ketut Karneli Ni Ketut Karneli Ni Made Suciani Nyoman Bayu Mahendra Puspa, Intan Putra, I Gede M Putu Adi Sujana Putra Putu Ayu Indrayathi Putu Doster Mahayasa R. Niruri Raharja, Fransiskus C Rasmaya Niruri Rasmaya Niruri Rasmaya Niruri Rini Noviyani Riza Firman Satria Sanjaya, I Nyoman H Santoso, Ferry Stella Kawilarang Stella Kawilarang, Stella Sugianto Sugianto Sumampouw, Janet Tjokorda Gde Agung Suwardewa Wenas, Yongki Yona S. Hadisubroto Yongki Wenas Yosevangelika Hutabarat