Claim Missing Document
Check
Articles

Found 18 Documents
Search

Pengaruh Suplementasi Vitamin C, Vitamin E, dan Kombinasinya Terhadap Penurunan Kadar Low Density Lipoprotein Serum pada Pasien Penyakit Ginjal Kronis Stadium V yang Dilakukan Hemodialisis Dewi, Ayu Kusuma; Purwanto, Bambang; Wiboworini, Budiyanti
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background:Low density lipoprotein (LDL) cholesterol is a prognostic factor for hemodialysis mortality through atherosclerosis mechanism. Vitamin C and E have been well known as anti-oxidants that reduced LDL cholesterol. However, there were no studies have been done to address the effectiveness of vitamin C, E, and its combination on lowering LDL in patients with hemodialysis. This study aimed to determine the effect of vitamin C, E, and C and E combination on LDL cholesterol. Methods:A randomized controlled trial was conducted in 64 patients receiving hemodialysis at RSUD Dr.Moewardi(RSDM) Surakarta. The sample was taken at random and then divided into 4 groups: placebo, vitamin C (500 mg), vitamin E (400 mg), and vitamin C + E combination. The treatment lasted for 30 days. LDL cholesterol before and after treatment were analyzed at the Clinical Pathology division, RSDM. The reduction in LDL cholesterol before and after treatment was analyzed using One Way Anovaand (pair-wise) Post-Hoc Test. Results:One Way Anovashowed statistically significant reduction in LDL cholesterol between groups (p<0.001). Post hoc testshowed that vitamin C, vitamin E, or its combination reduced LDL cholesterol more than the placebo (p<0.001). Vitamin C and E administered in combination led to statistically significant lower LDL cholesterol than administered alone (p=0.002). There was no statistically difference in LDL cholesterol level between those provided with vitamin C and vitamin E. Conclusion: Vitamin C and E, individually or in combination, reduces LDL cholesterol. The highest reduction was achieved by vitamin C and E combination.Keywords: vitamin C, vitamin E, LDL cholesterol
Hubungan rentang lengan, tinggi lutut, panjang ulna dengan tinggi badan lansia perempuan di Kecamatan Sewon Astriana, Kuntari; Wiboworini, Budiyanti; Kusnandar, Kusnandar
Ilmu Gizi Indonesia Vol 1, No 2 (2018): Februari
Publisher : Program Studi S-1 Ilmu Gizi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.975 KB)

Abstract

AbstrakLatar Belakang: Menjadi tua merupakan suatu proses alami yang tidak dapat dihindari. Selain masalah penyakit degeneratif seperti osteoporosis, malnutrisi juga merupakan masalah kesehatan lansia saat ini yaitu masalah gizi kurang dan gizi lebih. Penilaian status gizi lansia dapat diukur dengan menggunakan indeks massa tubuh (IMT) yaitu perbandingan berat badan dan kuadrat tinggi badan. Tinggi badan (TB) merupakan indikator status gizi sehingga pengukuran tinggi badan seseorang secara akurat sangatlah penting untuk menentukan nilai IMT. Akan tetapi untuk memperoleh pengukuran TB yang tepat pada lansia cukup sulit karena masalah postur tubuh, kerusakan spinal, maupun masalah dalam pergerakan. Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan rentang lengan, tinggi lutut dan panjang ulna dengan tinggi badan. Metode: Penelitian ini menggunakan desain cross sectional dan bersifat observasional analitik. Responden penelitian ini adalah lansia >60 tahun sebanyak 119 lansia. Hasil: Berdasarkan hasil analisis dengan menggunakan korelasi pearson terdapat hubungan yang bermakna antara rentang lengan, tinggi lutut, panjang ulna dengan tinggi badan. Tingkat keeratan hubungan untuk rentang lengan sebesar 0,779, tinggi lutut sebesar 0,639,dan panjang ulna sebesar 0,488. Rentang lengan, tinggi lutut, dan panjang ulna dapat digunakan untuk memprediksi tinggi badan lansia. Kesimpulan: terdapat hubungan yang bermakna antara rentang lengan, tinggi lutut, panjang ulna dengan tinggi badan Kata kunci: rentang lengan, tinggi lutut, panjang ulna, lansia 
The association between body mass index (BMI) and neck circumference with sleep quality Arum, Wuryan Dewi Miftahtyas; Wiboworini, Budiyanti; Kusumawati, Ratna
Nexus Kedokteran Komunitas Vol 3, No 2 (2014): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (287.047 KB)

Abstract

Backgrounds: Sleep disorders can affect on decreased concentration and academic achievement, sleepy while driving, risk behavior, depression, social interaction disorder, and bad health. Obesity is closely related to sleep-related breathing disorder that can affect on declining sleep quality as well. Body mass index (BMI) and neck circumference are simple screening to determine obesity. This research aims to know the association between BMI and neck circumference with sleep quality. Methods: This was an analytic observational research with cross sectional design in Buran Village, Tasikmadu, Karanganyar. Fifty six subjects 22-50 years of age were selected by using accidental sampling. BMI and neck circumference were obtained by anthropometric measurement. Sleep quality was obtained by PSQI questionnaire. Data were statistically analyzed using Spearman test and Mann-Whitney test. Results: The Spearman analysis indicated that there was no significant association between BMI and sleep quality (p = 0.070) as well as neck circumference and the sleep quality (p = 0.781). Mann Whitney analysis indicated that there was a significant association between psychological condition and sleep quality (p < 0.001). Conclusions: There are no significant associations between BMI and sleep quality as well as neck circumference and sleep quality. Psychological condition has significant correlation with sleep quality. Keywords: BMI, neck circumference, sleep quality
The Correlation Between Indicators of Obesity with Age at Menarche at Elementary School Female Students Retnowati, Sri; Wiboworini, Budiyanti; Kusumawati, Ratna
Nexus Kedokteran Komunitas Vol 4, No 1 (2015): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.679 KB)

Abstract

Background: Menarche is the first menstrual period in woman reproduction cycle. Recent studies show that the age at menarche is declining. Decline in age at menarche is correlated with obesity. This study aimed to identify the correlation between indicators of obesity with the age at menarche in elementary school students. Method: This was an analytical observational study with cross sectional approach. The subjects of this study were 58 female students of 5th-6th grade at SD Muhammadiyah 1 Surakarta and SD Kristen Manahan (elementary school) that taken by purposive sampling. Indicators of obesity (BMI, waist circumference, waist hip ratio) were measured by anthropometric. Age at  menarche was assessed by using questionnaire. The correlation between indicators of obesity with age at menarche had been analyzed by Spearman correlation test. Result: Spearman correlation test showed that there was no significant correlation between indicators of obesity (BMI, waist circumference, waist hip ratio) with age at menarche with result p=0.650; p=0.894; p=0.829. Spearman correlation test showed that there was no significant correlation between economic and mother’s age at menarche with respondent’s age at menarche (p=0.056 and p=0.087). Conclusion: There is no significant correlation between indicators of obesity with age at menarche in elementary school students. Keywords: indicator of obesity, BMI, waist circumference, waist hip ratio, age at menarche  
The Association between Eating Rate and Body Mass Index on Sixth Semester Female Medical Students of Sebelas Maret University Firnanda, Sani Widya; Wiboworini, Budiyanti; Widyaningsih, Vitri
Nexus Kedokteran Komunitas Vol 3, No 2 (2014): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.736 KB)

Abstract

Backgrounds: Many studies reported association between obesity and eating rate. Therefore, decreased eating rate is recommended to manage obesity. This study aims to analyze correlation between eating rate and body mass index. Methods: A quasi experimental study was conducted in a population of female students in the sixth semester of Faculty of Medicine, Sebelas Maret University. Fifty female students were gathered through purposive sampling methods with age 18 through 23 years old and body mass index ≥18.5. Eating rate was measured twice at breakfast with chicken noodle (521.7 kkal) and soto (233 kkal) on different day. Subjects were asked to eat in their normal pace and their eating rate were measured by stopwatch at the same time. Body mass index was measured by anthropometry. Statistical analysis was performed using simple linear regression. Results: Statistical analysis showed that there was significant association between eating rate and body mass index (p < 0.001) for both chicken noodle and soto. Simple linear regression indicated that higher eating rate was associated with higher body mass index and vice versa. The linear regression equation for chicken noodle was Body Mass Index = 34.837 – 1.577 (Eating Rate of Chicken Noodle) and the equation for soto was Body Mass Index = 36.696 – 1.837 (Eating Rate of Soto). Conclusions: There was significant association between eating rate and body mass index of female students in the sixth semester of Faculty of Medicine, Sebelas Maret University. Keywords: eating rate, satiety level, body mass index
Perbedaan Kekuatan Genggam Berdasarkan Status Gizi pada Pasien DM Tipe 2 (Handgrip Strength Difference based on Nutritional Status in Type 2 Diabetic Patients) Rohimah, Banun; Sugiarto, Sugiarto; Probandari, Ari; Wiboworini, Budiyanti
Indonesian Journal of Human Nutrition Vol 3, No 1 (2016): Suplemen "Malang Current Issues On Nutrition (MCION)"
Publisher : Jurusan Gizi, Fakultas Kedokteran, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (322.308 KB) | DOI: 10.21776/ub.ijhn.2016.003.Suplemen.2

Abstract

AbstrakDiabetes melitus (DM) merupakan masalah utama kesehatan masyarakat. Kondisi malnutrisi dapat terjadi pada pasien DM. Malnutrisi menyebabkan kelainan sensorimotor dan pengecilan otot yang bervariasi pada tiap tahapannya. Penilaian penurunan kekuatan genggam disarankan sebagai metode untuk mendeteksi kekurangan gizi di bidang klinik. Penelitian ini bertujuan untuk mengetahui perbedaan kekuatan genggam berdasarkan status gizi IMT pada pasien DM tipe 2. Penelitian ini bersifat observasional dengan rancangan cross sectional. Jumlah sampel adalah 153 pasien DM tipe 2 di Poliklinik Penyakit Dalam rawat jalan RSUD Dr. Moewardi Surakarta. Teknik pengambilan sampel adalah purposive sampling. Semua sampel diukur kekuatan genggam menggunakan handgrip dynamometer dan untuk Indeks Massa Tubuh (IMT) dengan penimbangan berat badan menggunakan timbangan digital dan pengukuran tinggi badan menggunaan microtoise kemudian dimasukkan rumus IMT. Analisis yang digunakan yaitu uji t independen untuk mengetahui perbedaan nilai rerata kekuatan genggam, perhitungan koefisien korelasi Pearson untuk mengetahui hubungan kekuatan genggam dengan IMT, dan model regresi linear untuk prediksi skor dari karakteristik ke variabel kekuatan genggam. Hasil penelitian menunjukkan bahwa pada 153 subjek memiliki rentang usia 38-68 tahun dengan rata-rata 56±7,13 tahun. Terdapat perbedaan kekuatan genggam berdasar jenis kelamin dan pekerjaan pada status gizi baik dan kurang, sedangkan perbedaan kekuatan genggam berdasar pendidikan hanya pada status gizi baik. Nilai kekuatan genggam antara status gizi kurang vs. status gizi baik = 22,28±9,69 kg vs. 22,98±8,27 kg (p=0,807). Dapat disimpulkan bahwa tidak terdapat perbedaan yang signifikan kekuatan genggam antara status gizi kurang dan status gizi baik berdasarkan IMT pada pasien DM tipe 2.Kata kunci : Kekuatan genggam, IMT, DM Tipe 2 AbstractDiabetes mellitus is a major health problem. Malnutrition is common among diabetic patients. Malnutrition may cause sensory motor disorders and muscle wasting in varying degrees. Handgrip strength (HGS) asessment is recommended to detect undernutrition in clinical practice. The aim of this study was to determine the HGS in type 2 diabetic patients. This was an observational study with cross sectional design. 153 type 2 diabetes outpatients of internal medicine clinic in Dr Moewardi Hospital, Surakarta were recruited using purposive sampling technique. HGS level was measured using handgrip dynamometer. The bodyweight and height were measured using digital weight scale and microtoise, respectively. The body mass index (BMI) was determined from body weight in kilograms divided by the square of height in meters. Independent sample t test was used to determine the difference of HGS level based of BMI index; Pearson correlation coefficient  measures the correlation between HGS and BMI while linear regression models were used to predict score from characteristic to HGS variable. Overall, 153 type 2 diabetes patients aged 38-68 year-old were participated in this study. The mean level of age was 56±7,13 year-old. The difference of HGS level was found based on gender and type of jobs, both normoweight and underweight group while HGS difference based on educational level was only found in normoweight group. HGS between underweight vs. normoweight group was 22,28±9,69 vs 22,98±8,27 kgs (p=0,807). There was no significant difference of HGS in type 2 diabetic patients with underweight and normoweight status.Keywords: Handgrip Strength, BMI, Type 2 Diabetes.
Path Analysis: Knowledge, Motivation Factor, and Their Relationship with Readiness to Provide Exclusive Breastfeeding among Pregnant Women Mulyani, Sri; Subiyanto, AA; Anantanyu, Sapja; Respati, Supriyadi Heri; Wiboworini, Budiyanti
International Research Journal of Management, IT & Social Sciences (IRJMIS) Vol 4 No 1: January 2017
Publisher : IJCU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21744/irjmis.v4i1.340

Abstract

Women who prepare early will be better prepared both physically and psychologically to breastfeed exclusively. The purpose of this research was to determine whether the motivation variable as a mediator of the relation between knowledge of exclusive breastfeeding with readiness to exclusive breastfeeding. The study was observational, A total of 150 respondents, These three variables, namely knowledge, motivation, and readiness in exclusive breastfeeding, measured by the enclosed questionnaire. Correlation between variables was analyzed with path analysis. The relation between variables in all three models was significant (p <0.001), whereas the relation between knowledge and preparedness in exclusive breastfeeding is not significant (1b = 0.142; p = 0.092). The relation between knowledge and preparedness in exclusive breastfeeding changed from the first model, into the fourth model. Besides there is a decline in the path coefficient of 0,302 became 0,142, the relation also becomes insignificant. This shows that the fourth mediation relationship condition is fulfilled. Pregnant women motivation exclusively breastfed mediates the relationship between knowledge of exclusive breastfeeding with maternal readiness in exclusive breastfeeding.
Pengaruh Konsumsi Buah Naga Merah (Hylocereus Costaricensis) Terhadap Kadar Glukosa Darah Puasa dan Kolesterol-Ldl pada Penderita Dm Tipe 2 Hapsari, Agustina Indri; Purwanto, Bambang; Wiboworini, Budiyanti
Jurnal Gizi dan Kesehatan Vol 2, No 1 (2015)
Publisher : Program Studi Ilmu Gizi Pascasarjana Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang : Diabetes Melitus (DM) merupakan kelompok penyakit metabolik kronik dengan karakteristik hiperglikemi yang meningkat prevalensinya di berbagai negara. Keadaan hiperglikemia pada DM menyebabkan terjadinya stres oksidatif yang dapat memacu terjadinya komplikasi baik mikro maupun makro vaskuler dengan indikator antara lain gula darah puasa dan kolesterol-LDL ˃ 100 mg/dL. Stres oksidatif dapat dihambat dengan mengkonsumsi makanan yang mengandung antioksidan yang tinggi. Buah naga merah mengandung sumber antioksidan yang tinggi. Penelitian ini bertujuan untuk mengetahui pengaruh konsumsi buah naga merah terhadap kadar glukosa darah puasa dan kolesterol-LDL pada penderita DM tipe 2.Metode : Penelitian ini adalah penelitian eksperimental klinis  dengan rancangan pre and post randomized controlled group design. Subjek penelitian adalah penderita DM tipe 2 di klub diabetisi Prolanis Poliklinik Rejosari Husada, Delanggu, Klaten. Kelompok perlakuan diberi buah naga merah dalam bentuk potongan sebanyak 180 gram/hari selama 15 hari. Kadar glukosa darah puasa dan kolesterol-LDL diukur sebelum dan sesudah perlakuan. Data dianalisis dengan uji Kolmogorov-Smirnov untuk uji normalitas data kadar glukosa darah puasa dan kolesterol-LDL, uji paired t-test untuk mengetahui perbedaan rerata pretest dan posttest dalam satu kelompok setelah dilakukan perlakuan, uji independent t-test untuk mengetahui perbedaan selisih rerata pretest dan posttest antara kelompok yang diberi perlakuan berbeda dan asupan gizi dari makanan hasil 24 hours food recall dianalisis dengan menggunakan program Nutrisurvey.Hasil  : Tidak terdapat penurunan kadar glukosa darah puasa baik pada kelompok perlakuan maupun pada kelompok kontrol. Terdapat penurunan signifikan kadar kolesterol-LDL sebelum dan sesudah perlakuan pada kelompok perlakuan (p 0,02), terdapat penurunan kadar kolesterol-LDL pada kelompok kontrol tidak signifikan (p 0,31) dan asupan energi dari makanan subjek rata-rata 134,46% kebutuhan rata-rata.Kesimpulan : Konsumsi buah naga merah dapat menurunkan kadar kolesterol-LDL pada penderita DM tipe 2. Konsumsi buah naga merah tidak dapat menurunkan kadar glukosa darah puasa pada penderita DM tipe 2. Pengaturan makan untuk pada pasien DM dengan pengendalian asupan terutama sumber energi penting dalam kendali kadar glukosa darah dan kolesterol-LDL. Keywords : buah naga merah, penderita DM tipe 2, glukosa darah puasa, kolesterol-LDL
PENGARUH SUPLEMENTASI BESI DAN KOMBINASI BESI DAN VITAMIN B6 TERHADAP KADAR HEMOGLOBIN TENAGA KERJA WANITA ANEMIA Mahyaningtyas, Fransisca Pradnya; Santoso, Santoso; Wiboworini, Budiyanti
Jurnal Gizi dan Kesehatan Vol 3, No 2 (2016)
Publisher : Program Studi Ilmu Gizi Pascasarjana Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang : Tenaga kerja wanita usia subur merupakan kelompok yang rentan terhadap anemia. Menurut data WHO, prevalensi anemia pada wanita usia subur adalah 30,2% atau sekitar 468,4 juta. Anemia yang sebagian besar diderita oleh wanita usia subur adalah anemia gizi besi. Beberapa penelitian suplementasi besi telah dilakukan dan hasilnya menunjukkan peningkatan kadar hemoglobin yang signifikan. Banyak zat gizi mikro yang digunakan meningkatkan penyerapan zat besi, misalnya vitamin B6. Vitamin B6 adalah salah satu jenis vitamin B yang berperan dalam pembentukan asam alfa-aminolevulinat, yaitu perkursor hem dalam hemoglobin. Penelitian ini bertujuan untuk mengetahui perbedaan efek suplementasi besi dengan kombinasi besi dan vitamin B6 terhadap kadar hemoglobin pada tenaga kerja wanita usia subur yang menderita anemia.Metode : Jenis penelitian yang digunakan adalah eksperimental, desain Randomized Controlled Trial pre-test post-test dengan double blind. Teknik pengambilan sampel dengan cara purposive sampling yang kemudian didapatkan 49 subjek penelitian. Pengambilan data menggunakan kuesioner data karakteristik, formulir food recall 24 jam, dan sampel darah vena. Data kadar hemoglobin diuji menggunakan independent t-test serta paired t-test .Hasil : Tidak ada perbedaan perubahan kadar hemoglobin yang bermakna baik pada kelompok yang diberi suplemen besi dan vitamin B6 maupun kelompok yang diberi suplemen besi saja yang ditunjukkan dengan nilai p yang tidak signifikan(p > 0,05).Kesimpulan : Suplementasi besi dan kombinasi besi dan vitamin B6 dapat meningkatkan kadar hemoglobin namun rata-rata kenaikannya tidak signifikan. Kata Kunci : suplementasi, hemoglobin, tenaga kerja wanita, anemia
Effect of Gestational Biological, Social, Economic Factors on Undernutrition in Infants 6-12 Months in Cilacap Septikasari, Majestika; Akhyar, Muhammad; Wiboworini, Budiyanti
Indonesian Journal of Medicine Vol 1, No 3 (2016)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (360.775 KB)

Abstract

Background: Undernutrition in children under five can cause disorder in the physical growth, mental development, low intellegence, or even death. This study aimed to test the hypothesis that under nutrition in infants aged 6-12 months is associated with gestational biological, social, and economic factors.Subjects and Method: This was an analytic and observational study with case control design. This study was conducted in Cilacap, Central Java. A total of 144 infants aged 6-12 months were selected by fixed disease sampling, consisting of 72 undernutrition cases and 72 control. The dependent variable was undernutrition. The independent variables were birthweight, breastfeeding complementary food intake, exclusive breastfeeding, maternal education, paternal education, family income, MUAC at pregnancy, intra-household food allocation, and rural-urban residence. The data were collected by questionnaire and anthropometry. The data were analyzed by multiple logistic regression.Results: Birthweight <2500 gram (OR=8.12; 95% CI=0.92 to 71.64; p=0.059), inadequate intake of breastfeeding complementary food (OR=3.93; 95% CI=1.59 to 9.75; p=0.003), and non-exclusive breastfeeding (OR=2.46; 95% CI=1.13 to 5.36;  p=0.023) increased the risk of undernutrition in infants aged 6-12 months. Paternal education (OR=1.50; 95% CI=0.61 to 3.71; p=0.377), family income (OR=2.54; 95% CI= 1.03 to 6.28; p=0.43), MUAC (OR=1.32; 95% CI=0.512 to 3.38; p=0.562), intra-household food allocation (OR=1.84; 95% CI=0.85 to 4.02; p=0.123), maternal education (OR=0.78; 95% CI=0.31 to 1.97; p=0.599) and rural-urban residence (OR=0.82; 95% CI= 0.36 to 1.85; p=0.630) had non-significant effect on the risk of undernutrition in infants aged 6-12 months.Conclusion: Birthweight <2500 gram, inadequate intake of breastfeeding complementary food, and non-exclusive breastfeeding increase the risk of undernutrition in infants aged 6-12 months. Paternal education, family income, MUAC, intra-household food allocation, maternal education and rural-urban residence have non-significant effect on the risk of undernutrition in infants aged 6-12 months.Keywords: birthweight, gestational, biological, social, economic factors, undernutrition, infants aged 6-12 monthsCorrespondence: Majestika Septikasari. School of Health Al-Irsyad Al-Islamiyyah Cilacap, Central Java. Email: jeaflava@gmail.comIndonesian Journal of Medicine (2016), 1(3): 184-194https://doi.org/10.26911/theijmed.2017.02.01.06