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All Journal Jurnal Kesehatan Andalas Jurnal Ilmiah Universitas Batanghari Jambi Journal of Midwifery Majalah Kedokteran Andalas Contagion: Scientific Periodical Journal of Public Health and Coastal Health Jurnal Ilmu Keperawatan dan Kebidanan Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks
Delmi Sulastri
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Analisis Faktor yang Berhubungan dengan Kinerja Bidan dalam Memberikan Pelayanan Antenatal Berkualitas Diwilayah Kerja Puskesmas Kota Bukittinggi Tahun 2018 Khairan Nisa; Joserizal Serudji; Delmi Sulastri
Jurnal Ilmiah Universitas Batanghari Jambi Vol 19, No 1 (2019): Februari
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.893 KB) | DOI: 10.33087/jiubj.v19i1.545

Abstract

Quality antenatal care has a major role in reducing maternal mortality. Every effort to improve quality must also be accompanied by efforts to pay attention to factors that contribute to improving the performance of midwives in providing services. The study used a combination of quantitative approaches in 67 midwives in the Bukittinggi and qualitatively in 15 informants, of which 9 people included in-depth interview informants to coordinator midwives, head of the Public health center and staffing and 6 FGD informants to midwives on duty at the health center.The results of quantitative data analysis, factors related to the performance of midwives are incentives, motivation and workload. Motivation is the most dominant factor related to the performance of midwives. The results of qualitative data analysis, the leadership plays an important role in increasing motivation to work midwives and optimizing the role of midwives in overcoming problems related to overlapping workloads. Midwives also need to increase their participation efforts and empower pregnant women so that programs can run well and provide positive feedback for improving the health status of pregnant women. Basically antenatal services provided by midwives are in accordance with standards, but the paradigm of antenatal care for pregnant women must shift from achieving quantity to focus on quality. To improve the performance of midwives in providing antenatal care, several efforts are needed: monitoring and evaluation of the quality of antenatal care by midwives, leadership involvement in efforts to increase midwife motivation both from supervision and reward management in non-material forms. Providing equal opportunities for midwives to improve competence through training, especially training related to quality antenatal care. In addition, the provision of infrastructure at the polindes needs attention. 
Faktor-Faktor yang Berhubungan dengan Status Gizi Anak Balita di Wilayah Kerja Puskesmas Nanggalo Padang Rona Firmana Putri; Delmi Sulastri; Yuniar Lestari
Jurnal Kesehatan Andalas Vol 4, No 1 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i1.231

Abstract

AbstrakStatus gizi anak balita salah satunya dipengaruhi oleh faktor kondisi sosial ekonomi, antara lain pendidikan ibu, pekerjaan ibu, jumlah anak, pengetahuan dan pola asuh ibu serta kondisi ekonomi orang tua secara keseluruhan. Penelitian ini dilakukan untuk mengetahui apakah ada hubungan kondisi sosial ekonomi keluarga terhadap status gizi anak balita. Penelitian ini adalah survei analitik menggunakan desain cross sectional study dengan jumlah sampel 227 orang yang terdiri dari anak balita dan ibu balita di Wilayah Kerja Puskesmas Nanggalo Padang. Data dikumpulkan melalui kuesioner yang telah diisi oleh ibu balita yang kemudian di analisis secara bivariat dan multivariat. Berdasarkan analisis bivariat didapatkan pendidikan ibu (p=0,022), pekerjaan ibu (p=0,000), pendapatan keluarga (p=0,012), jumlah anak (p=0,008) dan pola asuh ibu (p=0,000). Sementara dari analisis multivariat didapatkan pendidikan ibu (p=0,004; OR=2,594; CI95%=1,356-4,963), pekerjaan ibu (p=0,000; OR=74,769; CI95%=24,141-231,577), pendapatan keluarga (p=0,013; OR=3,058; CI95%=1,246-7,4) dan pola asuh ibu (p=0,000; OR=15,862; CI95%=5,973-42,128). Analisis bivariat menunjukan bahwa terdapat hubungan antara pendidikan ibu, pekerjaan ibu, pendapatan keluarga, jumlah anak dan pola asuh ibu dengan status gizi anak balita. Berdasarkan hasil analisis multivariat faktor pekerjaan ibu merupakan faktor yang paling berhubungan dengan status gizi anak balita.Kata kunci: status gizi, anak balita, faktor sosial ekonomiAbstractNutritional status of children under five years has affected by a political and socio-economic condition factors, among others, maternal education, maternal occupation, number of children, maternal knowledge and parenting also parents' economic conditions as a whole. This research is conduct to determine whether there is a relationship between the socio-economic conditions of families on the nutritional status of children under five.This research is a analytic survey using a cross sectional study design with the number of samples are 227 people consisting of children under five and the mothers in the working areas Puskesmas Nanggalo Padang. Data were collected through questionnaires which is completed by mothers whose later been analyzed in bivariate and multivariateBased on bivariate analysis we can get the maternal education (p = 0.022), maternal occupation (p = 0.000), household income (p = 0.012), number of children (p = 0.008) and maternal parenting (p = 0.000). While the multivariate analysis obtained from the maternal education (p = 0.004; OR = 2.594; CI95% = 1.356 to 4.963), maternal occupation (p = 0.000; OR = 74.769; CI95% = 24.141 to 231.577), household income (p = 0.013; OR = 3.058; CI95% = 1.246 to 7.4) and maternal parenting (p = 0.000; OR = 15.862; CI95% = 5.973 to 42.128).Bivariate analysis showed that there is a relationship between maternal education, maternal occupation, family income, number of children and parenting mothers with a nutritional status of children under five. Based on the results of the multivariate analysis, maternal occupation is the most associated factor with nutritional status of children under five.Keywords: Nutritional Status, Children Under Five, Socio-economic Factor
Hubungan Konsumsi Junk Food dengan Status Gizi Lebih pada Siswa SD Pertiwi 2 Padang Rizki Nur Amalia; Delmi Sulastri; Rima Semiarty
Jurnal Kesehatan Andalas Vol 5, No 1 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i1.466

Abstract

AbstrakGizi lebih adalah keadaan tubuh seseorang yang mengalami berat badan berlebih karena kelebihan jumlah asupan energi yang disimpan dalam bentuk cadangan berupa lemak. Prevalensi gizi lebih pada anak di Indonesia mencapai 10,4. Salah satu faktor risiko terjadinya gizi lebih adalah kebiasaan mengonsumsi junk food. Tujuan penelitian ini adalah menentukan hubungan antara konsumsi junk food dengan status gizi lebih pada anak usia sekolah. Penelitian ini adalah penelitian analitik dengan rancangan cross sectional terhadap populasi penelitian yaitu siswa kelas 1 – 5 di SD Pertiwi 2 Padang sebanyak 250 siswa. Teknik pengambilan data dilakukan dengan menggunakan kuesioner semi kuantitatif FFQ.  Status gizi ditentukan dengan pengukuran berat badan dan tinggi badan yang hasilnya dikategorikan menggunakan standar antropometri penilaian status gizi anak menurut Depkes Indonesia. Pada hasil penelitian didapatkan bahwa siswa yang memiliki status gizi lebih hanya 23,6% dengan rata – rata IMT 16,9±3,69. Rata – rata frekuensi konsumsi junk food 4,6±2,9 kali per hari dan rata – rata asupan energi junk food 1046,5±918,4 kkal per hari. Kesimpulan penelitian ini adalah terdapat hubungan yang bermakna antara konsumsi frekuensi konsumsi junk food dengan kejadian gizi lebih (p = 0,013) dan tidak terdapat hubungan yang bermakna antara asupan energi junk food dengan kejadian gizi lebih (p = 0,120).Kata kunci: gizi lebih, junk food, FFQ AbstractOverweight is a condition of an individual who suffer from excessive weight due to an excess of energy intake stored in fat tissue. Prevalence of overweight in children in Indonesia reaches 10,4 %. One of the risk factors contributing to this condition is consuming junk food. The objective of this study was to identify the relationship of junk food consumption and overweight in students. This research is an analytic study conducted in a cross sectional design using 250  students of class 1-5 in SD Pertiwi 2 Padang as subjects. The data was obtained using semi-quantitative FFQ. Nutrition status is defined using the measurement of body weight and height. The results are categorized using anthropometric standard for nutrition status assessment developed by Depkes Indonesia. The result revealed that the students with overweight was 23,6 % with average BMI of 16,9±3,69. The average frequency of junk food consumption was 4,6±2,9 times per day and the average energy intake from junk food was 1046,5±918,4 kcal per day. The conclusion is that the frequency of junk food consumption has a significant relationship to overweight and there’s no significant relationship between energi intake from junk food and overweight.Keywords: overweight, junk food, FFQ
Pengaruh Hiperglikemia terhadap Gambaran Histopatologis Pulau Langerhans Mencit Muhammad Farid; Eryati Darwin; Delmi Sulastri
Jurnal Kesehatan Andalas Vol 3, No 3 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i3.162

Abstract

AbstrakDiabetes mellitus menjadi ancaman global yang bersifat serius dengan prevalensi yang terus meningkat. Banyaknya teori patogenesis dan perjalanan penyakit yang melibatkan interaksi kompleks banyak faktor menyebabkan pendekatan terapi diabetes masih berpusat pada tindakan preventif dan diagnosis diabetes ditegakkan sepenuhnya dari ada atau tidaknya hiperglikemia. Penelitian ini bertujuan untuk mengetahui pengaruh hiperglikemia terhadap gambaran histopatologis pulau Langerhans mencit. Dua puluh empat (24) mencit Swiss Albino jantan dibagi dalam empat kelompok: satu kelompok kontrol (K) dan tiga kelompok perlakuan (G1, G2, G3). Kelompok perlakuan diinduksi untuk mengalami hiperglikemia melalui pemberian glukosa intraperitoneal dengan dosis berbeda (G1=2g/kgBB, G2=4g/kgBB, G3=6g/kgBB) selama 14 hari. Hasil analisis morfometrik menunjukan bahwa luas dan diameter pulau Langerhans meningkat pada kelompok G1 (p<0.01) namun menurun pada kelompok G2 (p<0.01) dan G3 (p<0.05). Jumlah sel endokrin pulau Langerhans meningkat pada kelompok G2 (p<0.05) dan G3 (p<0.01). Akan tetapi, tidak ada perbedaan yang bermakna pada jumlah sel endokrin pulau Langerhans pada kelompok K dan G1 (p>0.05). Densitas pulau Langerhans meningkat pada seluruh kelompok perlakuan (p<0.05) melalui mekanisme neogenesis. Kesimpulan penelitian ini adalah hiperglikemia yang diinduksi lewat pemberian glukosa secara intraperitoneal menyebabkan perubahan yang signifikan pada gambaran histopatologis pulau Langerhans mencit.Kata kunci: hiperglikemia, pulau Langerhans, gambaran histopatologisAbstractDiabetes mellitus become a serious health threat which prevalence have been increasing steadily all over the world. With complex interactions of risk factors on the disease, therapeutic approach of diabetes still centered on preventive measures and diagnosis was made entirely from the presence of hyperglycemia. The objective of this study was to determine the effect of hyperglycemia on histopathological features of islet of Langerhans, we examined pancreatic tissues from 24 male Swiss Albino mice: 6 control (K) and 18 glucose-treated mice with 3 different doses (G1=2g/kg, G2=4g/kg, G3=6g/kg) for 14 days to induce hyperglycemia. Morphometric analysis of islet of Langerhans on H&E-stained pancreatic sections showed that the islet area and diameter were increased in group G1 (48607.13 μm2 and 240713.25 nm, respectively; p<0.01) but decreased in group G2 (5471.42 μm2 and 81170.83 nm, p<0.01) and G3 (4628.07 μm2 and 74730.86 nm, p<0.05). The islet cells count was increased in group G2 (210.33 ± 18.66 cells/islet, p<0.05) and G3 (264.17 ± 75.52 cells/islet, p<0.01). However, there was no significant difference on islet cells count between group K and group G1 (p>0.05). Islet density was slightly increased in all treated group (p<0.05) through mechanism of neogenesis. The result suggest that hyperglycemia induced by administration of different doses of glucose intraperitoneally for 14 days caused significant changes in histopathological features of mice pancreatic islet.Keywords: hyperglycemia, islet of Langerhans,histopathologic features
Hubungan Indeks Massa Tubuh dengan Ketahanan Kardiorespirasi, Kekuatan dan Ketahanan Otot dan Fleksibilitas pada Mahasiswa Laki-Laki Jurusan Pendidikan Dokter Universitas Andalas Angkatan 2013 Haslan Muhaimin Lubis; Delmi Sulastri; Afriwardi Afriwardi
Jurnal Kesehatan Andalas Vol 4, No 1 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i1.213

Abstract

AbstrakKomponen kebugaran jasmani yang berhubungan dengan kesahatan adalah ketahanan kardiorespirasi, komposisi tubuh yang dinilai dengan Indek Massa Tubuh (IMT), kekuatan dan ketahanan otot dan fleksibilitas. Kebugaran jasmani bersifat individual. Tujuan penelitian ini adalah untuk mengetahui hubungan antara IMT dengan ketahanan kardiorespirasi, kekuatan dan ketahanan otot, dan fleksibilitas. Penelitian dilakukan pada mahasiswa Fakultas Kedokteran Universitas Andalas Padang pada bulan Nopember - Desember 2013. Penelitian ini merupakan studi observasional analitik menggunakan desain cross sectional study dengan jumlah 72 orang. Ketahanan kardiorespirasi didapat dengan menghitung nilai VO2maks menggunakan tes ergometer sepeda metode Astrand 6 minute cycle test. Dilakukan pengukuran berat badan dan tinggi badan. Kekuatan otot dinilai dengan hand dynamometer dan back strength dynamometer, ketahanan otot dinilai dengan bent leg sit-up dan fleksibilitas dinilai dengan sit and reach test, trunk extension, dan shoulder lift. Hasil pengukuran rerata IMT 22,08 ± 4,55, VO2maks 35,27 ± 2,25, grip strength kanan 32,44 ± 7,04, grip strength kiri 30,31 ± 7,2, back strength 100,9 ± 19,43, bent leg sit-up 29,29 ± 8,43 dalam 1 menit, sit and reach test 4,61 ± 2,61, trunk extension 29,21 ± 10,01, dan shoulder lift 38,06 ± 9,5.Kata kunci: BMI, VO2 maks, IMT, kekuatan dan ketahanan otot, fleksibilitasAbstractThe component of physical fitness which related to health are cardiorespiratory endurance, body composition (Body Mass Index/BMI), muscle strength and endurance, and flexibility. The objective of this research was to determine the relationship between BMI with cardiorespiratory endurance, muscle strength and endurance, and flexibility. This research has been done on male students of Medical Faculty of Andalas University on November – January 2013. This was a study observational analitic using design cross sectional study by the number of 72 people. Cardiorespiratory endurance obtained by calculating the value of bycycle ergometer test using VO2maks method astrand 6 minute cycle test, conducted measurement of height and weight, muscle strength is graded with a hand dynamometer and back strength dynamometer, muscle endurance is assessed with the bent leg sit-up, and flexibility with the sit and reach test, trunk extension, and shoulder lift. Data were analyzed by using SPSS. The result showed average body mass index 22,08 ± 4,55, VO2 max 35,27 ±2,25, right grip strength 32,44 ±7,04, left grip strength 30,31 ± 7,2, back strength 100,9 ±19,43, bent leg sit-up 29,29 ±8,43 in one minute, sit and reach test 4,61 ± 2,61, trunk extension 29,21 ±10,01, and shoulder lift 38,06 ±9,5.Keywords: BMI, VO2 maks, muscle strength and endurance, flexibility.
Hubungan Lesi Hiperemis di Gaster dengan Derajat Dispepsia pada Pasien Dispepsia Fungsional Vokal Furkano; Arina Widya Murni; Delmi Sulastri
Jurnal Kesehatan Andalas Vol 5, No 3 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i3.606

Abstract

AbstrakDispepsia fungsional didiagnosis jika esofagogastroduodenoskopi tidak menemukan penyebab organik yang dapat menjelaskan penyebab gejala. Patogenesis penyebab yang masih belum dipahami salah satunya dapat mempengaruhi permukaan mukosa lambung sehingga timbul lesi hiperemis di gaster yang mempengaruhi derajat dyspepsia. Tujuan penelitian ini adalah menentukan hubungan lesi hiperemis di gaster dengan derajat dispepsia pada pasien dispepsia fungsional. Penelitian dilakukan di RSUP Dr. M. Djamil Padang dari Juli sampai Oktober 2014. Sejumlah 35 penderita diambil berdasarkan kriteria inklusi dan eksklusi secara consecutive sampling non probability. Penderita dianamnesis menggunakan skor dispepsia untuk menentukan derajat dispepsia setelah itu dilakukan tindakan esofagogastroduodenoskopi untuk melihat keadaan mukosa lambung. Hasil penelitian terhadap 33 pasien dengan  hiperemis didapatkan 57.6% pasien memiliki derajat dispepsia sedang-berat dan terdapat hubungan ang tidak bermakna antara temuan lesi hiperemis dengan derajat dyspepsia. Hasil penelitian dari 19 pasien yang memiliki hiperemis luas didapatkan 73.7% pasien memiliki derajat dispepsia sedang-berat dan ini menunjukkan adanya hubungan yang bermakna antara luas hiperemis dengan derajat dispepsia pada pasien dispepsia fungsional dengan nilai kemaknaan 0.031 (p<0.05). Disimpulkan bahwa penderita yang mengalami derajat dispepsia sedang – berat memiliki daerah hiperemis luas.Kata kunci: dispepsia fungsional, lesi hiperemis di gaster, skor dispepsia AbstractFunctional dyspepsia is diagnosed if esophagogastroduodenoscopy does not show structural abnormalities explaining these symptoms. Many of etiologies that still less understanding to explain the pathogenesis can influence mucosal surface of stomach and make hyperemic lesion in the stomach that influent dyspepsia level. The objective of this study was to determine the relationship between hyperemic lesion in the stomach and dyspepsia level. This study was conducted in  Dr. M. Djamil Padang hospital from Juli until Oktober 2014. From 35 subjects were taken by inclusion and exclusion criteria and using consecutive sampling non probability. The subjects were interviewed using dyspepsia score to determine the dyspepsia level. The endoscopy will remain the initial investigation of choice for seeing the mucosal surface of gaster. The result showed from 33 samples that had hyperemic lesion 57.6% had moderate-severe dyspepsia level and there is no significant correlation of hyperemic lesion finding in the gaster with dyspepsia level but from 19 samples that had wide hyperemic lesion 73.7% had moderate-severe dyspepsia level and it showed it had significant correlation between both variables and the significant score is 0.031 (p<0.05). The conclusion is the subjects with intermediate – severe dyspepsia level have wide area of hyperemic lesion.Keywords: functional dyspepsia, hyperemic lesion in the stomach, dyspepsia score
Hubungan antara Indeks Massa Tubuh dengan Kadar Nitrit Oksid pada Masyarakat Etnik Minangkabau di Kota Padang Nidia Purwadianti; Fadil Oenzil; Delmi Sulastri
Jurnal Kesehatan Andalas Vol 4, No 2 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i2.255

Abstract

AbstrakObesitas merupakan masalah kesehatan yang kompleks dengan penyebab multifaktorial. Obesitas berkaitan erat dengan peningkatan risiko sejumlah komplikasi seperti hipertensi. Salah satu mekanisme yang menghubungkan obesitas dengan hipertensi adalah disfungsi endotel sebagai akibat penurunan kadar nitrit oksid (NO). Pengukuran Indeks Massa Tubuh (IMT) merupakan salah satu indikator untuk menentukan obesitas. .Tujuan penelitian ini ialah menentukan hubungan IMT dengan kadar nitrit oksid pada masyarakat etnik Minangkabau. Desain penelitian adalah studi potong lintang dengan populasi masyarakat etnik Minangkabau usia 30 – 65 tahun di 4 kecamatan terpilih di Kota Padang. Jumlah subjek sebanyak 130 orang. Data responden merupakan data sekunder yang dianalisis menggunakan uji korelasi Pearson dan uji beda rerata dengan metode independent sample t-test. Hasil penelitian pada kelompok obesitas diperoleh p-value = 0,982 dengan r = -0,003. Pada kelompok tidak obesitas didapatkan p-value = 0,924 dan r = -0,013. Berdasarkan hasil tersebut dapat disimpulkan bahwa tidak terdapat hubungan yang bermakna antara IMT dengan kadar NO. Kadar nitrit oksid rerata pada responden obesitas adalah 28,37±17,45 μmol/L dan tidak obesitas adalah 23,91±11,55 μmol/L dengan p-value=0,084. Terdapat perbedaan rerata kadar NO kelompok obesitas dan tidak obesitas pada masyarakat etnik Minangkabau di Kota Padang namun tidak bermakna secara statistik. Diharapkan penelitian lebih lanjut dengan mempertimbangkan faktor lain yang mempengaruhi kadar NO selain IMT.Kata kunci: indeks massa tubuh, kadar nitrit oksid, obesitas AbstractObesity is a complex health problem with multifactorial causes. Obesity is strongly related to risk increase of many complications such as hypertension. One of the mechanisms that links obesity and hypertension is endhotelial disfunction due to nitric oxide (NO) level decrease. Body Mass Index (BMI) measurement is one of the indicators to determine obesity. The objective of this study was to determine correlation between BMI and NO level in Minangkabau ethnic group. The research design was cross sectional study, the population was Minangkabau ethnic group in the age group of 30-65 years old from 4 selected districts in Padang. The total subjects were 130. The secondary data were analyzed by using Pearson correlation and mean difference test by using independent sample test method. The results obtained in obese groupare p-value=0.982 and r= -0.003. In non-obese group p-value = 0.924 and r = -0.013.Those findings suggest that there is no significant correlation between BMI and NO level. Mean NO level of obese group was 28.37±17.45 μmol/L and 23.91±11.55 μmol/L for non-obese group, p-value=0.084. It indicates that there is no significant correlation between obesity and NO level on Minangkabau ethnic group in Padang. It is suggested that other researchers conduct further research by considering other factors influencing NO level besides BMI.Keywords: body mass index, nitric oxide, obesity
Hubungan Aktivitas Fisik dengan Kadar Nitric Oxide (NO) Plasma pada Masyarakat di Kota Padang Ghozi Natul Isral; Afriwardi Afriwardi; Delmi Sulastri
Jurnal Kesehatan Andalas Vol 3, No 2 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i2.77

Abstract

AbstrakNitric oxide merupakan faktor relaksan yang disentesis oleh endotel pembuluh darah yang kadarnya dapat dipengaruhi oleh aktivitas fisik. Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik dengan kadar NO plasma pada masyarakat di kota Padang. Penelitian ini merupakan penelitian dengan data sekunder dari penelitian Delmi Sulastri dkk dalam “Pengaruh Asupan Antioksidan terhadap ekspresi Gen eNOS3 pada penderita Hipertensi Etnik Minangkabau”. Subyek penelitian adalah semua responden penelitian Delmi Sulastri dkk dalam “Pengaruh Asupan Antioksidan terhadap ekspresi Gen eNOS3 pada Penderita Hipertensi Etnik Minangkabau” berjumlah 130 orang yang dinilai aktivitas fisiknya dengan menggunakan kuisioner Baecke dkk. dan dilakukan pemeriksaan kadar NO plasma. Hasil penelitian menunjukkan bahwa sebagian besar responden memiliki tingkat aktivitas fisik ringan dan NO plasma rendah dengan dengan rerata 26,3±15,2 μmol/L. Dari analisis data didapatkan bahwa responden dengan aktivitas fisik ringan lebih banyak memiliki kadar NO plasma rendah (61,7%) dibandingkan kadar NO plasma normal (38,3%). Dari analisis statistik uji Chi-Square didapatkan nilai p = 0,007 yang berarti terdapat hubungan bermakna antara aktivitas fisik dengan kadar NO plasma (p<0,05). Kesimpulan penelitian ini adalah sebagian besar masyarakat di kota Padang memiliki tingkat aktivitas fisik ringan dan kadar NO plasma rendah. Dari uji statistik menunjukkan bahwa terdapat hubungan bermakna antara aktivitas fisik dengan kadar NO plasma pada masyarakat di kota Padang.Kata kunci: Aktivitas fisik, NOAbstractNitric oxide is relaxan factor that is synthesized by endothelial cell of blood vessel. From previous research showed that plasma NO level influenced by physical activity. The purpose of this study is to know correlation between physical activity with plasma NO level to Padang city people. The research is a research with secondary data by Delmi Sulastri et al., in “The Influence Of Antioksidan Intake to eNOS3 Gene Ekspression In Hypertension Patients In Minangkabau Ethnicity”. Participant of this research is all participant of Delmi Sulastri et al. research in “The Influence Of Antioksidan Intake to eNOS3 Gene Ekspression In Hypertension Patients In Minangkabau Ethnicity” with 130 participant. All participant were observed their physical activity using Baecke et al. quitionaire and were examined plasma NO level. Result of this study showed that most of responden have low physical activity level and low NO plasma level,with mean 26,3±15,2 μmol/L. From data analysis shows that subject with mild physical activity more had low plasma NO level (61,7%) than normal plasma NO level (38,3%). Then, from data analysis with Chi-Square test, found p value = 0,007. It mean, there is significant correlation between physical activity with NO plasma level (p<0.05). The summary of this study is most of Padang city people have mild physical activity level and low NO plasma level. From data statistics analysis showed that there is significant correlation betweeen physical activity with NO plasma level to people in Padang city.Keywords:Physical activity, NO
Hubungan Derajat Keasaman Cairan Lambung dengan Derajat Dispepsia pada Pasien Dispepsia Fungsional Emil Prasetyo Muhammad; Arina Widya Murni; Delmi Sulastri; Saptino Miro
Jurnal Kesehatan Andalas Vol 5, No 2 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i2.524

Abstract

AbstrakHipersekresi asam lambung dianggap penting sebagai salah satu mekanisme patologis dispepsia fungsional. Hipersekresi asam lambung dapat meningkatkan sekresi pepsin yang dapat menimbulkan kerusakan mukosa lambung pada dispepsia fungsional. Tujuan penelitian ini adalah menentukan hubungan derajat keasaman cairan lambung dengan derajat dispepsia yang dialami pasien dispepsia fungsional. Penelitian ini merupakan studi analitik dengan disain cross sectional yang dilakukan pada 35 sampel pasien dispepsia fungsional dengan teknik consecutive sampling di RSUP DR. M.Djamil Padang mulai Juli sampai Oktober 2014. Analisis data dilakukan secara komputerisasi menggunakan uji chi-square. Hasil penelitian didapatkan 51.4% pasien dispepsia fungsional memiliki derajat keasaman cairan lambung hyperacidity, 57.1% menderita dispepsia derajat sedang-berat, dan menunjukkan hubungan yang cukup kuat dengan tarif signifikansi (p) 0.029 (p < 0.05). Terdapat hubungan bermakna antara derajat keasaman cairan lambung dengan derajat dispepsia pada pasien dispepsia fungsional. Peningkatan derajat keasaman cairan lambung berbanding lurus dengan derajat dispepsia pada pasien dispepsia fungsional.Kata kunci: keasaman cairan lambung, derajat dispepsia, dispepsia fungsional AbstractGastric acid hypersecretion is considered important as one of the pathological mechanisms of functional dyspepsia. Gastric acid hypersecretion can increase the secretion of pepsin which can cause gastric mucosal damage in functional dyspepsia. The objective of this study was to determine the correlation of gastric juice acidity with dyspepsia level experienced by functional dyspepsia patients.This study was a analytic study with cross sectional design applied on 35 samples of functional dyspepsia patients with non-probability consecutive sampling technique at RSUP DR. M. Djamil Padang from July to October 2014. The data were computerized analyzed using chi-square test. The results showed 51.4% of patients with functional dyspepsia had hyperacidity gastric juice, 57.1% had moderate-to-severe dyspepsia level, and show a strong enough correlation with the rate of significance  0.029 (p < 0.05).There was a significant correlation between the gastric juice acidity with dyspepsia level of functional dyspepsia patients. Increase of gastric juice acidity is proportional to the dyspepsia level in functional dyspepsia patients.Keywords::gastric juice acidity, dyspepsia level, functional dyspepsia
Korelasi Kadar Hemoglobin dengan Kadar Nitric Oxide pada Preeklamsia dan Kehamilan Normal Siska Helina; Ariadi Ariadi; Delmi Sulastri
Jurnal Kesehatan Andalas Vol 4, No 3 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i3.368

Abstract

Abstrak Aktivasi sel endotel atau disfungsi endotel menjadi faktor utama patogenesis preeklamsia. Mekanisme ini ditandai dengan penurunan ketersedian Nitric Oxide (NO). Disfungsi endotel pada hipertensi diperkirakan berkaitan dengan konsentrasi hemoglobin. Tujuan penelitian ini adalah menentukan korelasi kadar hemoglobin dengan kadarNO pada preeklamsia dan kehamilan normal. Desain penelitian ini adalah analitik cross sectional, dilaksanakan di RSUP Dr. M. Djamil Padang dan RST Reksodiwiryo Padang dari 13 Mei sampai13 Juli 2014. Pemeriksaan kadar hemoglobin dilakukan di laboratorium Patologi Klinik RSUP Dr. M. Djamil Padang dan kadar NO di laboratorium Biomedik Fakultas Kedokteran UNAND Padang. Populasi penelitian ini adalah seluruh ibu hamil yang datang ke RSUP Dr. M. Djamil Padang dan RST Reksodiwiryo Padang. Sampel dipilih secara consecutive sampling jumlah sampel 17 orang kehamilan preeklamsia dan 18 kehamilan normal. Hasil penelitian menunjukkan pada preeklamsia kadar hemoglobin 12,39 ± 2,10gr/dl dan NO 29,88 ± 9,47µmol, sedangkan pada kehamilan normal 11,18 ± 0,98gr/dl dan NO 84,22 ± 54,26 µmol. Uji statistik menunjukkan ada korelasi positif yang bermakna (p = 0,02) antara kadar hemoglobin dan kadar NO pada preeklamsia. Tidah ada korelasi antara kadar hemoglobin dengan kadar NO pada kehamilan normal (p = 0,52). Kesimpulan dalam penelitian ini adalah peningkatan kadar hemoglobin cenderung meningkatkan kadar NO pada preeklamsia dan peningkatan kadar hemoglobin tidak mempengaruhi kadar NO pada kehamilan normal.Kata kunci:  hemoglobin, nitric oxide, preeklamsia, kehamilan normal Abstract Endothelial cell activation or dysfunction becomes a major factor pathogenesis of preeclampsia. This mechanism is characterized by the decrease of Nitric Oxide (NO) level. Endothelial dysfunction in hypertension is related to haemoglobin concentration, especially its role in vascular function. The objective of this study was to determine the correlation between haemoglobin level and NO level in preeclampsia and normal pregnancy. In this study, cross-sectional analytic design was used to determine relationship between haemoglobin and NO levels. Thisresearch was conducted in the clinic, emergency room, and delivery room of Dr. M. Djamil Hospital Padang and Reksodiwiryo Hospital in Padang from 13 th  May to 13 th  July 2014.  Haemoglobin levels were tested in clinical pathology laboratory of Dr. M. Djamil Padang Hospital and NO levels were tested in biomedical laboratory of Medicine faculty ofAndalas University. In this study, 17 preeclampsia pregnancies and 18 normal pregnancies were taken into samples in the hospitals, where the sample numbers were determined by using consecutive sampling method. The results show that in preeclampsia haemoglobin level is 12.39 ± 2.10g/dl and NO level is 29.88 ± 9.47 µmol, while in normalpregnancy, haemoglobin level is 11.18 ± 0.98g/dl and NO is 84.22 ± 54.26µmol respectively. Statistically there is positive significant correlation between haemoglobin level to NO level in preeclampsia (p = 0.02). There is no correlation between haemoglobin level to NO level in normal pregnancy (p = 0.52).  It can be concluded that haemoglobin level is inversely related to nitric oxide level in preeclampsia group. In normal pregnancy group, haemoglobin level is not associated to nitric oxide level.Keywords:  haemoglobin, nitric oxide, preeclampsia, normal pregnancy
Co-Authors Abd. Rasyid Syamsuri Afriwardi Afriwardi Amrina Amran Annisaul Husna Aprima Yona Amir Ariadi Ariadi Arina Widya Murni Arni Amir Desmawati Desmawati Elmatris Elmatris Emil Prasetyo Muhammad Eryati Darwin Eva Decroli Fadil Oenzil Fathiyyatul Khaira Ghozi Natul Isral Haslan Muhaimin Lubis Husnil Kadri Intan, Shinta Ayu Khairan Nisa Maretha Antya Tamimi Masrul Mayetti - Mifthahul Jannah Muhammad Rayyan Rifqi Nidia Purwadianti Noni Humaira Nur Afrainin Syah Nur Indrawaty Lipoeto Nuzulia Irawati Pudia M. Indika Rahmani Welan Rahmat Feryadi Rahmi Nurjannah Rahmi Ramadhani Rima Semiarty Rinaldiansyah Rinaldiansyah Rizki Nur Amalia Rona Firmana Putri Ryan Rhiveldi Keswani Saptino Miro Sidhi Sidhi Siska Helina Steffi Olivia Padriyani Susilasastri Susilasastri Try Rahmi Lussii Karsuita Tuti Gusra Ulya Uti Fasrini Vaulinne Basyir Vokal Furkano Yashinta Octavian Gita Setyanda Yuniar Lestari Yusrawati - Yusri Dianne Jurnalis