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All Journal Pharmaciana: Jurnal Kefarmasian KOVALEN: Jurnal Riset Kimia Lantanida Journal Jurnal Kesehatan Bakti Tunas Husada Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Journal of Pharmacopolium KLOROFIL: Jurnal Ilmu Biologi dan Terapan Dalton : Jurnal Pendidikan Kimia dan Ilmu Kimia JFL : Jurnal Farmasi Lampung Holistik Jurnal Kesehatan Minda Baharu JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) JURNAL FARMASIMED (JFM) Jurnal Pengabdian Kepada Masyarakat MEMBANGUN NEGERI Jurnal Kesehatan Poltekkes Kemenkes RI Pangkalpinang Community Development Journal: Jurnal Pengabdian Masyarakat SPIN: Jurnal Kimia & Pendidikan Kimia KLOROFIL: Jurnal Ilmu Biologi dan Terapan JURNAL KESEHATAN: JURNAL ILMIAH MULTI SCIENCES Sahabat Sosial: Jurnal Pengabdian Masyarakat International Journal of Health Sciences
MAURITZ PANDAPOTAN MARPAUNG
Universitas Kader Bangsa
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Analisis Efek Konsentrasi Ekstrak Etanol Daun Senggani (Melastoma malabathricum L.) sebagai Antibakteri Staphylococcus aureus Nurhayat, Nurhayat; Yuliar, Yuliar; Marpaung, Mauritz Pandapotan
JURNAL KESEHATAN POLTEKKES KEMENKES RI PANGKALPINANG Vol 8, No 1 (2020): JKP Juni 2020
Publisher : Poltekkes Kemenkes Pangkalpinang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32922/jkp.v8i1.115

Abstract

Latar belakang: Tanaman Senggani mempunyai banyak potensi sebagai pengobatan seperti antipiretik, analgesik, diuretik, dan antibakteri. Tujuan:untuk menganalisis efek konsentrasi ekstrak etanol daun senggani sebagai antibakteri Staphylococcus aureus. Metode: Daun senggani diekstraksi dengan perendaman dalam etanol 96%. Diameter zona hambat bakteri diukur dengan menggunakan metode difusi agar melalui lima perlakuan yaitu kontrol positif (kloramfenikol), kontrol negatif (NaCMC), dan ekstrak daun senggani konsentrasi 20%, 40%, 60%, dan 80%.Data yang dihasilkan dianalisis dengan metode statistik Kruskal-Wallis dan uji lanjut post hoc Mann Whitney. Hasil: Rata-rata diameter zona hambat pertumbuhan bakteri yang dihasilkan pada ekstrak 20% sebesar 12,5±1,00 mm; ekstrak 40% sebesar 14,75±0,96 mm; ekstrak 60% sebesar 17±0,82 mm; dan ekstrak 80% sebesar 19,5±1,00 mm.Hasil uji Kruskal-Wallis menunjukkan ada pengaruh antara rata-rata diameter zona hambat pertumbuhan bakteri Staphylococcus aureus dengan kelompok larutan uji (p
AKTIVITAS ANTIBAKTERI DAN ANTIJAMUR EKSTRAK BATANG AKAR KUNING (Fibraurea chloroleuca Miers) TERHADAP Escherichia coli, Staphylococcus aureus DAN Candida albicans Santoso, Udi; Utari, Medriana; Marpaung, Mauritz Pandapotan
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 20, No 2 (2020)
Publisher : STIKes Bakti Tunas Husada Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v20i2.611

Abstract

Akar kuning merupakan tanaman yang memiliki banyak khasiat khususnya bagian batang dalam pengobatan seperti antidiabetes, antiinflamasi, antikanker, dan antibiotik. Tujuan penelitian ini untuk menentukan aktivitas ekstrak batang akar kuning sebagai antibakteri terhadap Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923 dan antijamur terhadap Candida albicans 10231. Penelitian ini menggunakan metode difusi cakram dengan konsentrasi ekstrak yaitu 10%, 15%, dan 20%. Kontrol positif uji antibakteri dan antijamur masing-masing adalah amoksisilin dan ketokonazol dengan CMC sebagai kontrol negatif. Hasil penelitian menunjukkan rata-rata diameter hambat tertinggi terhadap pertumbuhan bakteri Escherichia coli dan Staphylococcus aureus terdapat pada ekstrak 20% masing-masing sebesar 26,5 mm dan 21,5 mm. Untuk rata-rata diameter hambat tertinggi terhadap pertumbuhan jamur Candida albicans terdapat pada ekstrak akar kuning 15% sebesar 23,2 mm. Kesimpulan dari penelitian adalah ekstrak batang akar kuning mempunyai aktivitas sebagai antibakteri terhadap Escherichia coli, Staphylococcus aureus dan antijamur terhadap Candida albicans. 
PENENTUAN PARAMETER SPESIFIK DAN NONSPESIFIK EKSTRAK KENTAL ETANOL BATANG AKAR KUNING (Fibraurea chloroleuca Miers) Marpaung, Mauritzs Pandapotan; Septiyani, Anggun
Journal of Pharmacopolium Vol 3, No 2 (2020)
Publisher : P3M STIKes Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jop.v3i2.622

Abstract

PENENTUAN KADAR FLAVONOID DARI EKSTRAK KULIT SALAK (Salacca zalacca. Reinw) BERDASARKAN PERBEDAAN PENGERINGAN SIMPLISIA Robbiyan Robbiyan; Mauritz Marpaung Pandapotan; Riza Apriani
Lantanida Journal Vol 9, No 1 (2021)
Publisher : UIN AR-RANIRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/lj.v9i1.8498

Abstract

The skin of the thorny palm has been empirically recognized by some people as a traditional medicine for beauty, antimicrobial, and antidiabetic. Compounds that act as treatment in the skin of the thorny palm is flavonoids. The study aims to determine the total flavonoid of the thorny palm rind extract based on differences in the drying of simplicia. The simplicia drying method used was oven-dry, direct sunlight, indirect sunlight, and air dry and fresh samples as control. Extraction using the maceration method with ethanol p.a. solvent. Determination of total flavonoid levels from the extract of thorny palm rind using the UV-Vis spectrophotometric method with quercetin standard solution. The qualitative test results showed that the skin of the thorny palm contains flavonoids after the addition of 1% AlCl3. The total flavonoid content in the fresh sample was 0.00342%, direct sunlight was 0.00350%, oven-dry was 0.00340%, dry air was 0.00357%, and indirect sunlight was 0.00361%. Therefore, it can be concluded that the highest flavonoid content in the extract of thorny palm rind is found in the indirect sun drying method.
Analisis Efek Konsentrasi Ekstrak Etanol Daun Senggani (Melastoma malabathricum L.) sebagai Antibakteri Staphylococcus aureus Nurhayat Nurhayat; Yuliar Yuliar; Mauritz Pandapotan Marpaung
JURNAL KESEHATAN POLTEKKES KEMENKES RI PANGKALPINANG Vol 8, No 1 (2020): JKP Juni 2020
Publisher : Poltekkes Kemenkes Pangkalpinang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32922/jkp.v8i1.115

Abstract

Latar belakang: Tanaman Senggani mempunyai banyak potensi sebagai pengobatan seperti antipiretik, analgesik, diuretik, dan antibakteri. Tujuan:untuk menganalisis efek konsentrasi ekstrak etanol daun senggani sebagai antibakteri Staphylococcus aureus. Metode: Daun senggani diekstraksi dengan perendaman dalam etanol 96%. Diameter zona hambat bakteri diukur dengan menggunakan metode difusi agar melalui lima perlakuan yaitu kontrol positif (kloramfenikol), kontrol negatif (NaCMC), dan ekstrak daun senggani konsentrasi 20%, 40%, 60%, dan 80%.Data yang dihasilkan dianalisis dengan metode statistik Kruskal-Wallis dan uji lanjut post hoc Mann Whitney. Hasil: Rata-rata diameter zona hambat pertumbuhan bakteri yang dihasilkan pada ekstrak 20% sebesar 12,5±1,00 mm; ekstrak 40% sebesar 14,75±0,96 mm; ekstrak 60% sebesar 17±0,82 mm; dan ekstrak 80% sebesar 19,5±1,00 mm.Hasil uji Kruskal-Wallis menunjukkan ada pengaruh antara rata-rata diameter zona hambat pertumbuhan bakteri Staphylococcus aureus dengan kelompok larutan uji (p
Effect of virgin coconut oil (VCO) on the physical stability of sweet potato leaf extract (Ipomoea batatas (L.) Lam) creams and antibacterial activity test against Staphylococcus aureus ATCC 25923 Mauritz Pandapotan Marpaung; Dani Prasetyo
Pharmaciana Vol 11, No 1 (2021): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (471.87 KB) | DOI: 10.12928/pharmaciana.v11i1.18575

Abstract

VCO (virgin coconut oil) has benefits for skin health such as softening the skin, maintaining skin health, and protecting the skin from radiation and free radicals. VCO as one of the raw materials for making cream preparations can affect its physical stability. This study aimed to analyze the effect of VCO on the physical stability of sweet potato leaf extract creams and antibacterial activity test against Staphylococcus aureus ATCC 25923. The creams were made with five formulas namely base, extract cream 2%, and VCO 1%, 3%, 5% added to the extract cream 2% respectively. Physical stability test included storage for six weeks at room temperature. Stability parameters were organoleptic observation, homogeneity, pH, spreadability, adhesivity, and cream type. Statistical analysis was carried out with the Anova and Kruskal Wallis tests. The organoleptic test results of the cream extract showed a distinctive odor, green color, with semisolid and homogeneous texture. Increasing the concentration of VCO will increase the spreadability of extract cream but did not affect pH and adhesion. The conclusion of this study was that extract cream 2% without the addition of VCO was the most stable cream formulation. Besides that, all the cream formulas did not show antibacterial activity against Staphylococcus aureus ATCC 25923.
Penentuan Aktivitas Antioksidan dan Kandungan Flavonoid Total Ekstrak Daun Papasan (Coccinia grandis L.) Berdasarkan Perbedaan Pelarut Polar : Determination of Antioxidant Activity and Total Flavonoid Contents Extract of Papasan Leaves (Coccinia grandis L.) Based on The Differences Polar Solvents Meliani Sari; Rani Nareza Ulfa; Mauritz Pandapotan Marpaung; Purnama
KOVALEN: Jurnal Riset Kimia Vol. 7 No. 1 (2021): Edisi April
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2021.v7.i1.15437

Abstract

Papasan leaves have several properties, including antihyperglycemic, diabetes, antipyretic and antioxidant. Minor metabolite compounds that have the potential as antioxidants from this plant are flavonoids, alkaloids, saponins, and tannins. This study's purpose to determine the antioxidant activity and the flavonoid total contents of Papasan (Coccinia grandis L.) leaf extract based on the differences in polar solvents. The polar solvents used were ethanol, methanol, and water. Extraction used by maceration and dekokta. The antioxidant activity and the flavonoid total contents were established by UV-Vis spectrophotometry according to the decrease in absorbance at a maximum wavelength of 515 nm by the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Determination of antioxidant activity and the flavonoid total contents were excluded on quercetin comparisons. The values of IC50 and the flavonoid total contents in the ethanol extract respectively were 287.92 ppm and 49.825 mg QE/g while the IC50 values and total flavonoid levels in the extract of methanol were 73.29 ppm and 50.415 mg QE/g. In the extract of the water, the value of IC50 was 39.80 ppm and the total flavonoid contents were 50.415 mg QE/g. The conclusions of these studies were that the most antioxidant activity was found in water extract, while water and methanol extract had the same and highest levels of total flavonoids.
Analisis Parameter Spesifik dan Nonspesifik Simplisia Daun Bawang Merah (Allium cepa L.): Analysis of Specific and Nonspecific Parameters of Shallot (Allium cepa L.) Leaves Simplicia Neneng Dwi Yana; Burhanudin Gummay; Mauritz Pandapotan Marpaung
KOVALEN: Jurnal Riset Kimia Vol. 8 No. 1 (2022): April Edition
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2022.v8.i1.15741

Abstract

Shallots are natural ingredients that are used as food enhancers for food and traditional medicines. This study aimed to analyze the specific and non-specific parameters of shallot (Allium cepa L.) Simplicia. Analysis of simplicia specific parameters in the form of material identity, organoleptic, macroscopic, and microscopic examination, levels of water-soluble extracts and ethanol soluble extracts while non-specifically in the form of a percentage of drying loss, water content, total ash, acid insoluble ash, and water-insoluble ash. The results of the research on specific parameters gave a yellowish-green simplicia color, a distinctive odor, in the form of powder, macroscopic examination of leeks elongated cylindrical, small round and hollow like a pipe, blunt leaf base, pointed leaf tip, green color, microscopic examination contained cover cells, gaps and epidermal cells, the levels for water-soluble extracts were 8.81±2.12%, the levels of ethanol-soluble compounds were 5.64±2.91%. The results of the study of non-specific parameters, the percentage of drying shrinkage was 0.89±0.57%, water content was 0.89±0.34%, total ash was 12.97±0.34%, acid-insoluble ash was 6.44±2.12%, and the water-insoluble ash content was 8.03±0.84%.
Penyuluhan Pemanfaatan Tanaman Obat Tradisional di Desa Telang Sari, Provinsi Sumatera Selatan Mauritz Pandapotan Marpaung; Dani Prasetyo
JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) VOL. 6 NOMOR 1 MARET 2022 JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat)
Publisher : Lembaga Publikasi Ilmiah dan Penerbitan (LPIP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.915 KB) | DOI: 10.30595/jppm.v6i1.7031

Abstract

Tanaman obat tradisional adalah tanaman yang yang diyakini secara turun-temurun untuk dimanfaatkan dan diolah secara tradisional sebagai pencegahan maupun pengobatan suatu penyakit.Oleh sebab itu perlu dilakukan sosialisasi melalui penyuluhan mengenai tujuan dan manfaat dari tanaman obat tradisional pada masyarakat khususnya di pedesaan. Pada kegiatan pengabdian pada masyarakat ini dilakukan penyuluhan di Desa Telang Sari, Kecamatan Tanjung Lago, Kabupaten Banyuasin, Provinsi Sumatera Selatan.Tujuan penyuluhan ini adalah memberikan pengetahuan dan pengalaman mengenai pemanfaatan tanaman tradisional. Penyuluhan ini dimulai dengan pemberian kuesioner, penyampaian materi, workshop, dan tanya jawab antara masyarakat dengan pemateri. Pada penyampaian materi menggunakan metode ceramah dengan bantuan slide powerpoint. Selain itu, pada workshop diperlihatkan cara membuat ramuan dari beberapa tanaman obat tradisional. Berdasarkan hasil penyuluhan ini menunjukkan masyarakat Desa Telang Sari mengetahui manfaat dari tanaman obat tradisional. Selain itu, masyarakat juga mengetahui cara membuat ramuan dari beberapa tanaman obat tradisional.
PENENTUAN KADAR ALKALOID TOTAL EKSTRAK AKAR KUNING (Fibraurea chloroleuca Miers) BERDASARKAN PERBEDAAN KONSENTRASI ETANOL DENGAN METODE SPEKTROFOTOMETRI UV-VIS Septia Wahyuni; Mauritz Pandapotan Marpaung
Dalton : Jurnal Pendidikan Kimia dan Ilmu Kimia Vol 3, No 2 (2020): (November) Dalton : Jurnal Pendidikan Kimia dan Ilmu Kimia
Publisher : Universitas Islam Kalimantan MAB Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (455.237 KB) | DOI: 10.31602/dl.v3i2.3911

Abstract

Akar kuning (Fibraurea chloroleuca Miers) dengan senyawa metabolit sekunder yang terkandung di dalamnya merupakan salah satu tanaman yang berpotensi sebagai tanaman obat tradisional untuk mengobati berbagai penyakit. Tujuan penelitian ini adalah menentukan kadar alkaloid total ekstrak akar kuning dengan perbedaan konsentrasi pelarut etanol yaitu 50%, 70%, dan 96%. Proses ekstraksi menggunakan metode maserasi dan ekstrak diuapkan dengan rotary evaporator pada suhu 40oC. Identifikasi alkaloid pada ekstrak menggunakan pereaksi Wagner, Mayer dan Dragendorff dan kadar alkaloid total dilakukan dengan metode spektrofotometri UV-Vis. Hasil penelitian menunjukkan identifikasi alkaloid dengan semua pereaksi dinyatakan positif mengandung alkaloid pada ekstrak. Hasil kadar alkaloid total ekstrak akar kuning dengan pelarut etanol 50% sebesar 0,6939 ± 0,2439%, dengan pelarut etanol 70% sebesar 0,6607 ± 0,2117% dan pelarut etanol 96% sebesar 0,7826 ± 0,3004%. Berdasarkan hasil penelitian, ekstrak akar kuning dengan konsentrasi pelarut etanol 96% menunjukkan kadar alkaloid yang tertinggi.
Co-Authors Alaiya Zulfana Avievi Albertus Ata Maran Aldise Indah Nurdevi Andi Alim, Andi Andi Bintang Arif Setiawansyah Baso Intang Sappaile Burhanudin Gummay Citra Azhariat Malasari Dani Prasetyo Dani Prasetyo Desna Ayu Wijayanti Devi Oktaria Diah Ayu Setiawati Dito Anurogo Ferry WF Waangsir Fitrah Fitrah Gusti Rusmayadi I Putu Agus Dharma Hita Jamisten Sigalinging Jasiyah, Rabiyatul Kamaruddin, Ilham Karlina Angga Pradhita Mayadiana Suwarma, Dina Meillisa Carlen Mainassy Meliani Sari Misbahul Munir Muhammad syafri Muntasir, Muntasir Musiana Musiana Muslimin Neneng Dwi Yana Neti Sulami Nia Agustina Niken Ayu Larasati Nurhaedah Nurhaedah Nurhayat Nurhayat Nurhayat Nurhayat, Nurhayat Purnama Purnama Purnama Rahmat Pannyiwi Rahmawati Rahmawati Rani Nareza Ulfa Rante, Anshar Ranti Ranti Ratna Ayu Dewi Rezqiqah Aulia Rahmat Rina Swita Esther Sitindaon Riza Apriani Robbiyan Robbiyan Romelan Romelan Rukmi Juwita Rusli Rusli Safridha Kemala Putri Saifullah Saifullah Santoso, Udi Septi Wulandari Septia Wahyuni Septiyani, Anggun Sitti Hasnah Sulfiani Sulfiani Susiyanti Susiyanti Syah, Setiawan Putra Tri Indah Utari, Medriana Waoma, Samalua Wensi Sapitri Weraman, Pius Wira Darma Yuliar Yuliar Yuliar Yuliar Yusrianto Yusrianto Zulkifli Halid