MARTHA ARDIARIA
Department Of Nutrition Science, Faculty Of Medicine, Universitas Diponegoro, Jl. Prof. Sudarto No.13, Tembalang, Semarang 50275

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Efek integrated nutrition programme terhadap profil lipid dan komposisi tubuh pada remaja obes Martha Ardiaria; Erin Ratna Kustanti; Ria Purnawian Sulistiani; Etika Ratna Noer
Jurnal Gizi Klinik Indonesia Vol 15, No 3 (2019): Januari
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.31594

Abstract

The effect of integrated nutrition programme on lipid profile and body composition among adolescent obesityBackground: Obesity is a serious public health issue increasingly in the adolescent. Obesity in adolescence will continue into adulthood and lead to later health problems. The adolescent has high food dense calories which high fat and low in fiber that can trigger obesity. Integrated Nutrition Programme (INP) is an intervention model for obesity with an emphasis on a low-calorie diet, low fat, high fiber, moderate physical activity, and nutrition counseling.Objective: This study aimed to evaluate the effect of INP on lipid profile and body composition in obese adolescents.Methods: Quasi-experimental study pre-post trial design with a total of subjects 18 obese adolescents. Duration of intervention in subjects for four weeks with a hypocaloric diet, low fat, high fiber, and prepared by a dietician. Moderate exercise and dietary counseling were conducted on the subject regularly. Bodyweight (BW) and waist circumference (WC) were monitored once a week. Food record intake is done before and during the intervention.Results: The mean weight loss of 1.55 kg. There is a difference in mean BW, WC, and BMI (p<0.01), whereas there were no significant differences in lipid profiles and body composition between before and after the intervention.Conclusions: INP can significantly affect weight loss, BMI, and WC as well as a significant increase in physical activity.
Irregular menstrual cycles as a risk factor of type 2 diabetes mellitus in women of childbearing age Dhea Aghestya; Nurmasari Widyastuti; Martha Ardiaria; Fillah Fithra Dieny
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 1, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss1.art5

Abstract

Background: Irregular menstrual cycles are a risk factor for developing type 2 diabetes mellitus (DM) in women. Objective: This study aimed to evaluate irregular menstrual cycles as a risk factor of type 2 DM in women of childbearing age with body fat percentage, waist-hip ratio, diet quality, and physical activity as confounding factors.Methods: This was a case-control study. Its subjects were subjects with type 2 diabetes mellitus (n=31) and subjects without any clinical evidence of abnormal glucose regulation (n=31) who attended Puskesmas (Community Health Centre) Rowosari, Tembalang, Semarang with over 30 years of age. Based on their menstrual cycles, they were divided into two groups: women with irregular menstrual cycles, and those with regular menstrual cycles. Cochran Mantel-Haenszel test was used to control their confounding factors. Results: There was an association between irregular menstrual cycles and type 2 DM (p<0.05) with a 7.2 greater risk on women of childbearing age (OR = 7.2, 95% CI=2.18-23.75). By the Cochran Mantel-Haenszel test, the association was still significant; women with over percentage of body fat and central obese with irregular menstrual cycle had 4,85 times and 4,37 times of sequentially greater risk on type 2 DM (OR = 4.85, 95% CI=0.98-23.95 vs OR = 4.37, 95% CI=0.93-20.51).Conclusion: The irregular menstrual cycles was a risk factor of type 2 DM, especially in obese women of childbearing age.
PERBEDAAN EFEK SEDUHAN KULIT DAN JUS BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUS) TERHADAP KADAR KOLESTEROL LDL SERUM TIKUS SPRAGUE DAWLEY DISLIPIDEMIA Rani Puspita; Martha Ardiaria; Ahmad Syauqy
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.451 KB) | DOI: 10.14710/dmj.v5i4.15815

Abstract

Latar Belakang : Dislipidemia adalah keadaan ketidaknormalan kadar lemak dalam darah. Buah naga merah (Hylocereus polyrhizus) mengandung polifenol, antioksidan dan serat dalam jumlah tinggi. Polifenol mempunyai kemampuan dalam menurunkan kadar kolesterol LDL pada manusia dan tikus.Tujuan : Mengetahui perbedaan efek seduhan kulit dan jus buah naga merah terhadap kadar kolesterol LDL serum tikus Sprague dawley dislipidemia.Metode : Penelitian ini merupakan penelitian eksperimental dengan desain pre and posttest control group design. Sampel adalah 24 ekor tikus Sprague dawley dengan kriteria tertentu, dibagi secara acak menjadi 4 kelompok yaitu kelompok kontrol negatif yang hanya diberi pakan standar, kontrol positif diberikan pakan standar dan pakan tinggi kolesterol, dua kelompok perlakuan diberikan pakan standar, pakan tinggi kolesterol, seduhan kulit 9,08g/200gbb tikus dan jus buah naga merah 1,53g/200gbb tikus, pemberian intervensi diberikan selama 14 hari. Kadar LDL diperiksa dengan metode CHOD-PAP dan GPO-PAP. Data dianalisis dengan uji Paired t-test dan AnovaHasil : Tidak terdapat perbedaan bermakna sebelum dan setelah intervensi pada kelompok K(-). Namun terdapat perbedaan bermakna sebelum dan sesudah intervensi pada kelompok K(+), P1, dan P2. Pemberian seduhan kulit dan jus buah naga mera selama 14 hari dapat menurunkan kadar LDL (43,33 ± 3,65) dan (27.56±8,01). Setelah intervensi terdapat perbedaan rerata kadar LDL antar kelompok p=0,000 kecuali K(-) dengan seduhan kulit p=0,640.Simpulan : Pemberian seduhan kulit dengan dosis 9,08g/2000gbb tikus dan jus buah naga merah 1,53g/200gbb tikus selama 14 hari dapat menurunkan kadar LDL pada tikus sprague dawley jantan sebesar 43,33 ± 3,65 dan 27.56±8,01.
PERBEDAAN EFEK SEDUHAN KULIT DAN JUS BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP KADAR TRIGLISERIDA SERUM TIKUS Sprague dawley DISLIPIDEMIA I Dewa Gede Angga Pramana; Martha Ardiaria; Ahmad Syauqy
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.333 KB) | DOI: 10.14710/dmj.v5i4.14461

Abstract

Latar Belakang : Dislipidemia merupakan abnormalitas profil lipid dalam serum, salah satunya adalah peningkatan kadar trigliserida serum. Buah naga merah (Hylocereus polyrhizus) terbukti memperbaiki profil lipid karena adanya kandungan fenolat dan flavonoid. Kulit buah naga merah mengandung kandungan gizi seperti karbohidrat, lemak, protein, serat dan senyawa betasianin.Tujuan : Mengetahui perbedaan efek pemberian seduhan kulit dan jus daging buah naga merah terhadap kadar trigliserida serum tikus Sprague dawley dislipidemia.Metode : Jenis penelitian adalah true experimental dengan pre and post test with control group design. Sampel adalah tikus jantan Sprague dawley usia 10 minggu, diinduksi dislipidemia dengan telur puyuh dan asam kolat. Pada kelompok K(-) diberi pakan standar, kelompok K(+) diberi pakan tinggi kolesterol, kelompok P1 diberi seduhan kulit buah naga merah dan kelompok P2 diberi jus buah naga merah. Kadar trigliserida serum diperiksa dengan metode CHOD-PAP dan GPO-PAP. Data kemudian dianalisis menggunakan uji paired t test dan one way ANOVA.Hasil : Terdapat perbedaan bermakna sebelum dan setelah intervensi pada kelompok K(-), K(+), P1 dan P2. Pemberian seduhan kulit selama 14 hari dapat menurunkan kadar trigliserida sebesar 53,61 mg/dl (SD= 4,06) sedangkan jus buah naga merah dapat menurunkan kadar trigliserida sebesar 36,99 mg/dl (SD= 8,14). Setelah intervensi terdapat perbedaan rerata kadar trigliserida antar kelompok p=0,000 kecuali K(-) dengan seduhan kulit p=1,000.Simpulan : Pemberian seduhan kulit buah naga merah dan jus daging buah naga merah selama 14 hari dengan dosis 9,08 g/200 gbb tikus dan 1,53 g/200 gbb tikus dapat menurunkan kadar trigliserida serum masing-masing sebesar 53,61 mg/dl (SD= 4,06) dan 36,99 mg/dl (SD= 8,14) pada tikus Sprague dawley dislipidemia.