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Perry Boy Chandra Siahaan
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Computer Science & IT Dentistry Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Other

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Journal : Jurnal Biogenerasi

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PERBANDINGAN UJI DIAGNOSTIK GENEXPERT MTB/RIF DENGAN KULTUR SENSITIVITAS ANTIBIOTIK DALAM MENDETEKSI RESISTENSI RIFAMPICIN Mycobacterium tuberculosis PADA PASIEN TB PARU DI RSUP H. ADAM MALIK MEDAN Nurbaity Situmorang; Perry Boy Chandra Siahaan; Suharsih; Dewi Novina Sukapiring
Jurnal Biogenerasi Vol. 7 No. 2 (2022): Jurnal Biogenerasi Vol 7 Nomor 2 tahun 2022
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v7i2.1912

Abstract

WHO recommends GeneXpert Mycobacterium tuberculosis; Rifampicin as an initial examination for the diagnose of drug-resistant tuberculosis and drug-sensitive tuberculosis in pulmonary TB patients. The GeneXpert MTB/RIF examination is a molecular examination method with Nucleic Acid Amplification Technology (NAAT) which can diagnose TB and resistance to Rifampicin within 2 hours. The aims of this study is to determine the comparison of GeneXpert MTB/Rif Diagnostic Test with Drug Sensitivity Culture in Detecting Rifampicin M. tuberculosis resistance in TB patients at H. Adam Malik Hospital, Medan. The sample in this study was the entire population of suspected pulmonary TB at H. Adam Malik Hospital Medan who had MTB examination results. Post; rif. res. The sample size was using total sampling, namely the sampling technique where the number of samples was the same as the population, namely 128 patients in 2020. The results of the Rifampicin TCM Antibiotic Test were found that 128 people had Rifampicin Resistant results. Based on the percentage of the results of the MGIT Antibiotic Sensitivity Test, 125 people were found to have Rifampicin Resistant results and 3 people had Rifampicin Sensitive results. Based on the results, it can be seen that the sensitivity value of the TCM tool to DST MGIT culture is 97.7%. The Conclusions of these Research is the ability of the GeneXpert MTB/Rif method to detect rifampin resistance can be used as a screening tool to diagnose rifampin-resistant TB.
Co-Authors Abdul Wahab Agung Nugroho Andry Simanullang Andry Simanullang Ayu Sibagariang Bara Mega Nawawi Buenita Buenita Buenita Sinurat Devita Butar Butar Dewi Novina Sukapiring Dheanissa Syalwa Khabija Irawan Diah Ayu Souchi Eka Lolita Eliyanti Pakpahan Eka Lolita Eliyanti Pakpahan Elisa Christy Simanjuntak Elvia Grace Damanik Eva Ellya Sibagariang Eva Flourentina Kusumawardani Eva Flourentina Kusumawardani Eva Flourentina Kusumawardani Febriyanti Febriyanti Firman Firdauz Saputra Grace Silvany Purba Gunarto Sinaga Hamidah Rizki Hartono Hartono Hartono Hartono Herbert Wau Herlina Natalina Hutasoit Hiswani Hiswani Imanuel Sibero Johannes Bastira Ginting Junaita Lambuena Br Sitorus Junita Sitorus Laila Apriani Hasanah Harahap Laila Apriani Hasanah Harahap Lisa Kristin Karolina Zendrato Zendrato Lukman Nurhakim Mafe Robbi Simanjuntak Mafe Robbi Simanjuntak Mardi Fadilah Mardi Fadillah Margaretha Febrina Br Ginting Margaretha Febrina Ginting Mariana Natalie Bangun Masryna Siagian Meutia Paradhiba Meutia Paradhiba NASRIANTI SYAM Nasrianti Syam Nurbaity Situmorang Nurul Wahyuni Onetusfifi Putra Onetusfifsi Putra Pahala J Simangunsong Pahala Maringan J Simangunsong Putranto Manalu Putri Yunita Pane Rafael Ginting Rahayu Lubis Rapael Ginting Ridho Afriansyah P Rihan Wirda Asdani Risya Yoela Sinaga Rubi Rimonda Rubi Rimonda Rubi Rimonda Santy Deasy Siregar Suharsih Sylvira Rianda Tariana Ginting Tarianna Ginting Victor Trismanjaya Hulu Vince Prima Waruwu Yosephin Putri C Manalu Yuna Asima Ria Lumban Gaol