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Mustofa Mustofa
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Journal : Mandala of Health : A Scientific Journal

 1 
THE EFFECT OF SALIVARY TESTOSTERONE LEVELS ON HEART RATE VARIBILITY ON STUDENTS OF MEDICAL FACULTY OF JENDRAL SOEDIRMAN UNIVERSITY Widad Nurul Nadiyah; Mustofa Mustofa; Wahyu Djatmiko; Rizak Tiara Yusan
Mandala Of Health Vol 15 No 1 (2022): Mandala Of Health
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (406.082 KB) | DOI: 10.20884/1.mandala.2022.15.1.6352

Abstract

Testosterone is a steroid hormone produced by Leydig cells in testis. Testosterone levels can be measured through a saliva sampel. Testosterone have effect in the cardiovascular system. Testosterone can affect cardiac contractility and has a cardioprotective role in maintaining the autonomic balance of the heart. Cardiac autonomic activity can be assessed by Heart Rate Varibility (HRV). This study aims to determine the effect of salivary testosterone levels on HRV in FK Unsoed students. This study was an analytic observational study with a cross sectional approach. The number of subjects in this study were 31 students who were taken by consecutive sampling, with inclusion criteria, namely male gender, age 17-25 years, agreed to the informed consent, BMI 18,5-24,9 kg/m2, body temperature 36,5-37,5 ℃, and low to moderate level of physical activity. Testosterone levels were measured using the Salimetrics ELISA method. HRV were measured using a POLAR M400 heart rate monitor and the Welltory application with the result of HRV parameters in the form of SDNN. The data normality test used the Saphiro-Wilk test. Bivariate analysis used Pearson’s correlative parametric test. The subjects of the study had a low mean testosterone saliva levels, namely 12,38±3,70 pg/mL and a low mean SDNN of 56,74±19,70 ms. The results of the Pearson correlation test of testosterone with SDNN shows the value of r = 0,147 and the value of p = 0,429, so it can be concluded that there is no correlation between testosterone saliva levels and HRV in SDNN parameters.
CORRELATION OF SALIVARY TESTOSTERONE LEVELS WITH EXTROVERTED PERSONALITY IN STUDENTS OF THE FACULTY OF MEDICINE JENDERAL SOEDIRMAN UNIVERSITY Ahmad Firdaus Firman Maulana; Mustofa Mustofa; Khusnul Muflikhah
Mandala Of Health Vol 15 No 1 (2022): Mandala Of Health
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.903 KB) | DOI: 10.20884/1.mandala.2022.15.1.6354

Abstract

Testosterone is the main male sex hormone produced by Leydig cells in the testis. Measurement of testosterone levels can use saliva samples. Testosterone has many roles in reproductive and non-reproductive functions, such as behavior. Behavior includes aggressive and dominant traits. Aggressive behavior has a relationship with extrovert personality. This study aims to determine the correlation of salivary testosterone levels with extroverted personality in students of the Faculty of Medicine Jenderal Soedirman University. This study is observational with a cross-sectional study design. The number of subjects in this study was 26 students taken with consecutive sampling, with inclusion criteria of male aged 17-25 years, agreed to informed consent, BMI 18-24,9 kg/m2, didn’t smoke, and didn’t consume alcohol. Testosterone level was measured with a Salimetrics ELISA kit. Measurement of extrovert personality using the MBTI questionnaire. The normality test of the data used the Saphiro-Wilk test and bivariate analysis using the Pearson correlative parametric test. The results of measurements on the subjects obtained salivary testosterone levels 11,64±2,51 pg/mL and extrovert personality 41,02±19,74 %. The results of the Pearson correlation test salivary testosterone with extroverted personality values obtained p = 0,007 and r = 0,517 which means that there is a significant correlation between salivary testosterone levels and extrovert personality. The conclusion of this study is there is a correlation between salivary testosterone levels and extrovert personality in students of the Faculty of Medicine Jenderal Soedirman University.
Co-Authors A.M. Wara Kusharwanti agus prasetyo aji Ahmad Firdaus Firman Maulana Ahmad Khoirul Fata Ahmad Mahfudzi Mafrudlo Andi Idhan Andi Namirah Muh. Syuaib AS Andre Yasip Hastadi Ane Tika Wahyuni Ani Nurfaizah anis wihdayanti Ardiansyah Ardiansyah Arina Selawati Arya Indra Madani Asri Widowati atiq fauziyah Aula Ahmad Hafidh Saiful Fikri Bambang Winarno Dhaniel Hutagalung Djoko Wahyono Dzicky Rifqi Fuadi Eko Surjadi Eman Singgih Endang Darmawan Eva Agistiawati Evi Mulyani Fatrilia Rasyi Radita Fetri Wahyuningsih Fitranto Arjadi FX Pudjo Wibowo Ghizela Fineartha Fauzi Gusli Chidir Heni Komalasari Ibrahim Arifin IGP Suryadarma Ilham Nur Leksono Intan Qori Lutfiyani Iqmal Tahir Iskandar Iskandar Isnatin Miladiyah Jumina Jumina Khusnul Muflikhah Kristian Selleng Mainatul Ilmi Maryanto Masarrang Masduki Asbari Muhammad Izzatul Faqih Muhammad Roestam Afandi Musriatun Napiah Nasrudin Nasrudin Nita Kusumawardani Noor Hafizah Nur Signa Aini Gumilas Nurasiah Nurasiah nurul latifah Purwanto Purwanto Raafi Aditya Nugraha Rachma Darma Astuti Rachmad Syafa'at Rachmawati Darma Astuti Rahmat Yanuar Rahmawati Dharma Astuti Ratna Asmah riyanta aribawa Rizak Tiara Yusan Rokhani Rokhani Roni Mohamad Sari Dewi Shehona Abdul Gufron Siti Maesaroh Sofia Mubarika H Sri Haryanti Sucipto Basuki Sulastri Sulastri Sumani Sumani Sundari Juni Astuti Supriyadi Supriyadi Susiana Candrawati Titi Rohimah Tri Murti Andayani TRI WIDIASTUTI Wahyu Djatmiko Widad Nurul Nadiyah Wijoyo Wijoyo Wiwiek Fatchurohmah Yadi Janwari Yasir Mahaseng Yayah Yulia Yayuk Dwi Rahayu Yudhi Wibowo Yuli Asmi Rahman Yusnaini Arifin Zuhratul Aini Mansur